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PMC:7571312 / 17892-18333 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T29395 156-161 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T77718 228-233 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T39660 329-334 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T54465 405-409 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T44584 410-415 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T3 405-409 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T56 85-89 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T35747 36-38 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T36376 148-155 http://purl.obolibrary.org/obo/CLO_0009526 denotes Vero 76
T60100 156-161 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T41307 220-227 http://purl.obolibrary.org/obo/CLO_0009526 denotes Vero 76
T44344 228-233 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T95747 271-279 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T41737 324-328 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T58120 324-328 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T23029 329-334 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T96607 399-404 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T31340 405-409 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T79444 405-409 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T79987 410-415 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T305 4-24 Chemical denotes 2,6-dichlorobenzoate http://purl.obolibrary.org/obo/CHEBI_48624
T306 110-119 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T307 261-270 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T9 289-300 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T10 352-358 http://purl.obolibrary.org/obo/GO_0140352 denotes efflux
T11 352-358 http://purl.obolibrary.org/obo/GO_0140115 denotes efflux

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T116 0-441 Sentence denotes The 2,6-dichlorobenzoate derivative 22 displays the highest levels of potency in the SARS CoV-1 3CLpro and in antiviral cytopathic effect assays in Vero 76 cells (EC50 = 0.29 ± 0.19 μM).39 We note here that the assay in Vero 76 cells provided data establishing antiviral activity, but the translation of potency measured in Vero cells, which have high efflux potential, to the potency achievable in human lung cells was unknown (vide infra).

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
497 85-93 Species denotes SARS CoV Tax:694009
498 399-404 Species denotes human Tax:9606
500 4-24 Chemical denotes 2,6-dichlorobenzoate