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PMC:7571312 / 17288-17622
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T71020","span":{"begin":210,"end":218},"obj":"Body_part"}],"attributes":[{"id":"A7931","pred":"fma_id","subj":"T71020","obj":"http://purl.org/sig/ont/fma/fma13478"}],"text":"We can conclude that this water must be an acceptor to His41 as one of the water hydrogens is engaged with acceptor electrons on the side chain of Asp187, and the second hydrogen engages a terminating acceptor backbone carbonyl on Asp176 through a short network that includes the side chains of an internal, neutral His164 and Thr175."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T75567","span":{"begin":187,"end":188},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T94234","span":{"begin":246,"end":247},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"We can conclude that this water must be an acceptor to His41 as one of the water hydrogens is engaged with acceptor electrons on the side chain of Asp187, and the second hydrogen engages a terminating acceptor backbone carbonyl on Asp176 through a short network that includes the side chains of an internal, neutral His164 and Thr175."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T296","span":{"begin":26,"end":31},"obj":"Chemical"},{"id":"T297","span":{"begin":43,"end":51},"obj":"Chemical"},{"id":"T298","span":{"begin":75,"end":80},"obj":"Chemical"},{"id":"T299","span":{"begin":107,"end":115},"obj":"Chemical"},{"id":"T300","span":{"begin":170,"end":178},"obj":"Chemical"},{"id":"T301","span":{"begin":201,"end":209},"obj":"Chemical"},{"id":"T302","span":{"begin":219,"end":227},"obj":"Chemical"}],"attributes":[{"id":"A296","pred":"chebi_id","subj":"T296","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A297","pred":"chebi_id","subj":"T297","obj":"http://purl.obolibrary.org/obo/CHEBI_15339"},{"id":"A298","pred":"chebi_id","subj":"T298","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_15339"},{"id":"A300","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_49637"},{"id":"A301","pred":"chebi_id","subj":"T301","obj":"http://purl.obolibrary.org/obo/CHEBI_15339"},{"id":"A302","pred":"chebi_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/CHEBI_23019"}],"text":"We can conclude that this water must be an acceptor to His41 as one of the water hydrogens is engaged with acceptor electrons on the side chain of Asp187, and the second hydrogen engages a terminating acceptor backbone carbonyl on Asp176 through a short network that includes the side chains of an internal, neutral His164 and Thr175."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T112","span":{"begin":0,"end":334},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We can conclude that this water must be an acceptor to His41 as one of the water hydrogens is engaged with acceptor electrons on the side chain of Asp187, and the second hydrogen engages a terminating acceptor backbone carbonyl on Asp176 through a short network that includes the side chains of an internal, neutral His164 and Thr175."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"481","span":{"begin":26,"end":31},"obj":"Chemical"},{"id":"482","span":{"begin":55,"end":60},"obj":"Chemical"},{"id":"483","span":{"begin":75,"end":80},"obj":"Chemical"},{"id":"484","span":{"begin":81,"end":90},"obj":"Chemical"},{"id":"485","span":{"begin":147,"end":153},"obj":"Chemical"},{"id":"486","span":{"begin":170,"end":178},"obj":"Chemical"},{"id":"487","span":{"begin":231,"end":237},"obj":"Chemical"},{"id":"488","span":{"begin":316,"end":322},"obj":"Chemical"},{"id":"489","span":{"begin":327,"end":333},"obj":"Chemical"}],"attributes":[{"id":"A481","pred":"tao:has_database_id","subj":"481","obj":"MESH:D014867"},{"id":"A483","pred":"tao:has_database_id","subj":"483","obj":"MESH:D014867"},{"id":"A484","pred":"tao:has_database_id","subj":"484","obj":"MESH:D006859"},{"id":"A486","pred":"tao:has_database_id","subj":"486","obj":"MESH:D006859"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"We can conclude that this water must be an acceptor to His41 as one of the water hydrogens is engaged with acceptor electrons on the side chain of Asp187, and the second hydrogen engages a terminating acceptor backbone carbonyl on Asp176 through a short network that includes the side chains of an internal, neutral His164 and Thr175."}