PMC:7571312 / 13863-14100 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T84592","span":{"begin":5,"end":7},"obj":"http://purl.obolibrary.org/obo/CLO_0008307"}],"text":"n of P2 and amine capping structural elements provided inhibitors 4 and 38–50.\nScheme 3 Preparation of Hydroxymethylketone Derivatives\n(i) 4 M HCl/dioxane, (ii) Boc-Leu-OH, HATU, NMM, DMF, 0 °C, (iii) HATU, 4-MeO-2-indolecarboxylic acid"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T212","span":{"begin":5,"end":7},"obj":"Chemical"},{"id":"T213","span":{"begin":12,"end":17},"obj":"Chemical"},{"id":"T214","span":{"begin":55,"end":65},"obj":"Chemical"},{"id":"T215","span":{"begin":144,"end":147},"obj":"Chemical"},{"id":"T216","span":{"begin":148,"end":155},"obj":"Chemical"},{"id":"T217","span":{"begin":162,"end":165},"obj":"Chemical"},{"id":"T218","span":{"begin":166,"end":169},"obj":"Chemical"},{"id":"T221","span":{"begin":185,"end":188},"obj":"Chemical"},{"id":"T222","span":{"begin":216,"end":237},"obj":"Chemical"},{"id":"T223","span":{"begin":233,"end":237},"obj":"Chemical"}],"attributes":[{"id":"A212","pred":"chebi_id","subj":"T212","obj":"http://purl.obolibrary.org/obo/CHEBI_33472"},{"id":"A213","pred":"chebi_id","subj":"T213","obj":"http://purl.obolibrary.org/obo/CHEBI_32952"},{"id":"A214","pred":"chebi_id","subj":"T214","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A215","pred":"chebi_id","subj":"T215","obj":"http://purl.obolibrary.org/obo/CHEBI_17883"},{"id":"A216","pred":"chebi_id","subj":"T216","obj":"http://purl.obolibrary.org/obo/CHEBI_46923"},{"id":"A217","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_48502"},{"id":"A218","pred":"chebi_id","subj":"T218","obj":"http://purl.obolibrary.org/obo/CHEBI_15603"},{"id":"A219","pred":"chebi_id","subj":"T218","obj":"http://purl.obolibrary.org/obo/CHEBI_25017"},{"id":"A220","pred":"chebi_id","subj":"T218","obj":"http://purl.obolibrary.org/obo/CHEBI_30006"},{"id":"A221","pred":"chebi_id","subj":"T221","obj":"http://purl.obolibrary.org/obo/CHEBI_17741"},{"id":"A222","pred":"chebi_id","subj":"T222","obj":"http://purl.obolibrary.org/obo/CHEBI_38610"},{"id":"A223","pred":"chebi_id","subj":"T223","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"n of P2 and amine capping structural elements provided inhibitors 4 and 38–50.\nScheme 3 Preparation of Hydroxymethylketone Derivatives\n(i) 4 M HCl/dioxane, (ii) Boc-Leu-OH, HATU, NMM, DMF, 0 °C, (iii) HATU, 4-MeO-2-indolecarboxylic acid"}

{"project":"LitCovid-sentences","denotations":[{"id":"T73","span":{"begin":79,"end":135},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"n of P2 and amine capping structural elements provided inhibitors 4 and 38–50.\nScheme 3 Preparation of Hydroxymethylketone Derivatives\n(i) 4 M HCl/dioxane, (ii) Boc-Leu-OH, HATU, NMM, DMF, 0 °C, (iii) HATU, 4-MeO-2-indolecarboxylic acid"}

{"project":"LitCovid-PubTator","denotations":[{"id":"362","span":{"begin":5,"end":7},"obj":"Chemical"},{"id":"363","span":{"begin":12,"end":17},"obj":"Chemical"},{"id":"365","span":{"begin":104,"end":123},"obj":"Chemical"},{"id":"384","span":{"begin":162,"end":165},"obj":"Gene"},{"id":"385","span":{"begin":144,"end":147},"obj":"Chemical"},{"id":"386","span":{"begin":148,"end":155},"obj":"Chemical"},{"id":"387","span":{"begin":174,"end":178},"obj":"Chemical"},{"id":"388","span":{"begin":180,"end":183},"obj":"Chemical"},{"id":"389","span":{"begin":185,"end":188},"obj":"Chemical"},{"id":"390","span":{"begin":202,"end":206},"obj":"Chemical"},{"id":"391","span":{"begin":208,"end":237},"obj":"Chemical"}],"attributes":[{"id":"A362","pred":"tao:has_database_id","subj":"362","obj":"MESH:C020845"},{"id":"A363","pred":"tao:has_database_id","subj":"363","obj":"MESH:D000588"},{"id":"A384","pred":"tao:has_database_id","subj":"384","obj":"Gene:91653"},{"id":"A385","pred":"tao:has_database_id","subj":"385","obj":"MESH:D006851"},{"id":"A386","pred":"tao:has_database_id","subj":"386","obj":"MESH:C025223"},{"id":"A387","pred":"tao:has_database_id","subj":"387","obj":"MESH:C472082"},{"id":"A388","pred":"tao:has_database_id","subj":"388","obj":"MESH:C035596"},{"id":"A389","pred":"tao:has_database_id","subj":"389","obj":"MESH:D004126"},{"id":"A390","pred":"tao:has_database_id","subj":"390","obj":"MESH:C472082"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"n of P2 and amine capping structural elements provided inhibitors 4 and 38–50.\nScheme 3 Preparation of Hydroxymethylketone Derivatives\n(i) 4 M HCl/dioxane, (ii) Boc-Leu-OH, HATU, NMM, DMF, 0 °C, (iii) HATU, 4-MeO-2-indolecarboxylic acid"}