PMC:7571312 / 13460-13809 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T27962","span":{"begin":32,"end":35},"obj":"http://purl.obolibrary.org/obo/CLO_0002526"},{"id":"T47002","span":{"begin":56,"end":58},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"}],"text":"Alternatively, fully elaborated CMK derivatives such as 35 were reacted with benzoylformic acid followed by methanolysis to generate HMK final products such as 36.36 Alkylation of the terminal hydroxyl was achieved under microwave-assisted conditions in the presence of silver (I) oxide to afford alkoxymethylketone inhibitors, as illustrated by 37."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T204","span":{"begin":91,"end":95},"obj":"Chemical"},{"id":"T205","span":{"begin":193,"end":201},"obj":"Chemical"},{"id":"T207","span":{"begin":270,"end":276},"obj":"Chemical"},{"id":"T209","span":{"begin":281,"end":286},"obj":"Chemical"},{"id":"T211","span":{"begin":316,"end":326},"obj":"Chemical"}],"attributes":[{"id":"A204","pred":"chebi_id","subj":"T204","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A205","pred":"chebi_id","subj":"T205","obj":"http://purl.obolibrary.org/obo/CHEBI_29191"},{"id":"A206","pred":"chebi_id","subj":"T205","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A207","pred":"chebi_id","subj":"T207","obj":"http://purl.obolibrary.org/obo/CHEBI_30512"},{"id":"A208","pred":"chebi_id","subj":"T207","obj":"http://purl.obolibrary.org/obo/CHEBI_9141"},{"id":"A209","pred":"chebi_id","subj":"T209","obj":"http://purl.obolibrary.org/obo/CHEBI_25741"},{"id":"A210","pred":"chebi_id","subj":"T209","obj":"http://purl.obolibrary.org/obo/CHEBI_29356"},{"id":"A211","pred":"chebi_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"}],"text":"Alternatively, fully elaborated CMK derivatives such as 35 were reacted with benzoylformic acid followed by methanolysis to generate HMK final products such as 36.36 Alkylation of the terminal hydroxyl was achieved under microwave-assisted conditions in the presence of silver (I) oxide to afford alkoxymethylketone inhibitors, as illustrated by 37."}

{"project":"LitCovid-sentences","denotations":[{"id":"T71","span":{"begin":0,"end":349},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Alternatively, fully elaborated CMK derivatives such as 35 were reacted with benzoylformic acid followed by methanolysis to generate HMK final products such as 36.36 Alkylation of the terminal hydroxyl was achieved under microwave-assisted conditions in the presence of silver (I) oxide to afford alkoxymethylketone inhibitors, as illustrated by 37."}

{"project":"LitCovid-PubTator","denotations":[{"id":"358","span":{"begin":77,"end":95},"obj":"Chemical"},{"id":"359","span":{"begin":193,"end":201},"obj":"Chemical"},{"id":"360","span":{"begin":270,"end":286},"obj":"Chemical"},{"id":"361","span":{"begin":297,"end":315},"obj":"Chemical"}],"attributes":[{"id":"A358","pred":"tao:has_database_id","subj":"358","obj":"MESH:C012482"},{"id":"A359","pred":"tao:has_database_id","subj":"359","obj":"MESH:D017665"},{"id":"A360","pred":"tao:has_database_id","subj":"360","obj":"MESH:C040225"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Alternatively, fully elaborated CMK derivatives such as 35 were reacted with benzoylformic acid followed by methanolysis to generate HMK final products such as 36.36 Alkylation of the terminal hydroxyl was achieved under microwave-assisted conditions in the presence of silver (I) oxide to afford alkoxymethylketone inhibitors, as illustrated by 37."}