PMC:7571312 / 115766-116672 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T72 284-285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 859-861 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T74 898-903 http://purl.obolibrary.org/obo/CLO_0007706 denotes M – H

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T54398 77-83 Chemical denotes chloro http://purl.obolibrary.org/obo/CHEBI_47853
T34240 86-89 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T22447 120-126 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T32734 127-133 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T16199 134-139 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T54946 140-148 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T29365 150-163 Chemical denotes 3-methylbutyl http://purl.obolibrary.org/obo/CHEBI_30359
T13674 167-174 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T74571 175-184 Chemical denotes 1H-indole http://purl.obolibrary.org/obo/CHEBI_16881
T80619 175-177 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T24048 178-184 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_35581
T3894 187-198 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T27297 216-222 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581
T2161 225-240 Chemical denotes carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575
T56450 236-240 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T39246 378-386 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T33818 387-402 Chemical denotes dichloromethane http://purl.obolibrary.org/obo/CHEBI_15767
T20847 468-470 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T74007 485-489 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T16982 506-508 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T63708 532-534 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T2955 558-560 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T44220 603-605 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T9758 629-631 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T33550 643-645 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T69327 669-671 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T40756 745-747 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T90580 764-766 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T82858 783-785 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T32498 859-861 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T624 0-304 Sentence denotes Following the procedure described for the preparation of N-((1S)-1-{[((1S)-3-chloro-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}-3-methylbutyl)-4-methoxy-1H-indole-2-carboxamide but substituting indole-2-carboxylic acid and making noncritical variations provided a crude orange foam.
T625 305-467 Sentence denotes This material was purified by Biotage flash chromatography, eluting with methanol/dichloromethane to afford the title compound as an off-white solid, 1.75 g, 82%.
T626 468-906 Sentence denotes 1H NMR (400 MHz, DMSO-d6) δ 11.58 (s, 1H), 8.64 (d, J = 7.8 Hz, 1H), 8.50 (d, J = 7.8 Hz, 1H), 7.55–7.69 (m, 2H), 7.42 (d, J = 8.3 Hz, 1H), 7.26 (d, J = 1.5 Hz, 1H), 7.16 (m, 1H), 7.02 (t, J = 7.5 Hz, 1H), 4.53–4.66 (m, 2H), 4.39–4.52 (m, 2H), 2.94–3.18 (m, 2H), 2.22–2.35 (m, 1H), 2.03–2.16 (m, 1H), 1.89–2.02 (m, 1H), 1.45–1.82 (m, 5H), 0.93 (d, J = 6.3 Hz, 3H), 0.88 (d, J = 6.3 Hz, 3H); MS (APCI−) for C23H29N4O4Cl m/z 459.1 (M – H)−.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2049 216-240 Chemical denotes indole-2-carboxylic acid MESH:C058980
2050 378-386 Chemical denotes methanol MESH:D000432
2051 387-402 Chemical denotes dichloromethane MESH:D008752