PMC:7571312 / 113974-114490 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7571312","sourcedb":"PMC","sourceid":"7571312","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7571312","text":"m, 4H), 1.67–1.53 (m, 4H), 0.88 (s, 9H); MS (ESI+) for C21H35N3O6m/z 426 (M + H). HRMS (ESI+) calcd for C21H35N3O6+H1 426.2599, found 426.2604.\n\n4-Methoxy-N-((1S)-1-{[((1S)-3-methoxy-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}-3-methylbutyl)-1H-indole-2-carboxamide (48)\nA solution of N-((1S)-1-{[((1S)-3-hydroxy-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}-3-methylbutyl)-4-methoxy-1H-indole-2-carboxamide (185 mg, 0.39 mmol), iodomethane (0.12 mL, 2.0 mmol), and silver(I","divisions":[{"label":"title","span":{"begin":145,"end":292}}],"tracks":[{"project":"LitCovid-PD-CLO","denotations":[{"id":"T63","span":{"begin":41,"end":43},"obj":"http://purl.obolibrary.org/obo/CLO_0007874"},{"id":"T64","span":{"begin":74,"end":79},"obj":"http://purl.obolibrary.org/obo/CLO_0007706"},{"id":"T65","span":{"begin":289,"end":291},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T66","span":{"begin":293,"end":294},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T63","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T31599","span":{"begin":41,"end":43},"obj":"Chemical"},{"id":"T89775","span":{"begin":175,"end":182},"obj":"Chemical"},{"id":"T65814","span":{"begin":185,"end":188},"obj":"Chemical"},{"id":"T51895","span":{"begin":219,"end":225},"obj":"Chemical"},{"id":"T17086","span":{"begin":226,"end":232},"obj":"Chemical"},{"id":"T87780","span":{"begin":233,"end":238},"obj":"Chemical"},{"id":"T18055","span":{"begin":239,"end":247},"obj":"Chemical"},{"id":"T38903","span":{"begin":249,"end":262},"obj":"Chemical"},{"id":"T38323","span":{"begin":264,"end":273},"obj":"Chemical"},{"id":"T35868","span":{"begin":264,"end":266},"obj":"Chemical"},{"id":"T54851","span":{"begin":267,"end":273},"obj":"Chemical"},{"id":"T25452","span":{"begin":276,"end":287},"obj":"Chemical"},{"id":"T96709","span":{"begin":295,"end":303},"obj":"Chemical"},{"id":"T78225","span":{"begin":327,"end":334},"obj":"Chemical"},{"id":"T53284","span":{"begin":337,"end":340},"obj":"Chemical"},{"id":"T68087","span":{"begin":371,"end":377},"obj":"Chemical"},{"id":"T34247","span":{"begin":378,"end":384},"obj":"Chemical"},{"id":"T10126","span":{"begin":385,"end":390},"obj":"Chemical"},{"id":"T17616","span":{"begin":391,"end":399},"obj":"Chemical"},{"id":"T42313","span":{"begin":401,"end":414},"obj":"Chemical"},{"id":"T23058","span":{"begin":418,"end":425},"obj":"Chemical"},{"id":"T46947","span":{"begin":426,"end":435},"obj":"Chemical"},{"id":"T8538","span":{"begin":426,"end":428},"obj":"Chemical"},{"id":"T48591","span":{"begin":429,"end":435},"obj":"Chemical"},{"id":"T47040","span":{"begin":438,"end":449},"obj":"Chemical"},{"id":"T81598","span":{"begin":471,"end":482},"obj":"Chemical"},{"id":"T54246","span":{"begin":508,"end":514},"obj":"Chemical"}],"attributes":[{"id":"A62720","pred":"chebi_id","subj":"T31599","obj":"http://purl.obolibrary.org/obo/CHEBI_73613"},{"id":"A93197","pred":"chebi_id","subj":"T89775","obj":"http://purl.obolibrary.org/obo/CHEBI_32772"},{"id":"A23255","pred":"chebi_id","subj":"T89775","obj":"http://purl.obolibrary.org/obo/CHEBI_44520"},{"id":"A32218","pred":"chebi_id","subj":"T65814","obj":"http://purl.obolibrary.org/obo/CHEBI_46629"},{"id":"A88071","pred":"chebi_id","subj":"T51895","obj":"http://purl.obolibrary.org/obo/CHEBI_32875"},{"id":"A84467","pred":"chebi_id","subj":"T51895","obj":"http://purl.obolibrary.org/obo/CHEBI_29309"},{"id":"A83976","pred":"chebi_id","subj":"T17086","obj":"http://purl.obolibrary.org/obo/CHEBI_26308"},{"id":"A90311","pred":"chebi_id","subj":"T87780","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A43932","pred":"chebi_id","subj":"T18055","obj":"http://purl.obolibrary.org/obo/CHEBI_23019"},{"id":"A59720","pred":"chebi_id","subj":"T38903","obj":"http://purl.obolibrary.org/obo/CHEBI_30359"},{"id":"A38046","pred":"chebi_id","subj":"T38323","obj":"http://purl.obolibrary.org/obo/CHEBI_16881"},{"id":"A60191","pred":"chebi_id","subj":"T35868","obj":"http://purl.obolibrary.org/obo/CHEBI_49637"},{"id":"A27842","pred":"chebi_id","subj":"T54851","obj":"http://purl.obolibrary.org/obo/CHEBI_35581"},{"id":"A38590","pred":"chebi_id","subj":"T25452","obj":"http://purl.obolibrary.org/obo/CHEBI_23004"},{"id":"A57535","pred":"chebi_id","subj":"T25452","obj":"http://purl.obolibrary.org/obo/CHEBI_37622"},{"id":"A74636","pred":"chebi_id","subj":"T96709","obj":"http://purl.obolibrary.org/obo/CHEBI_75958"},{"id":"A88282","pred":"chebi_id","subj":"T78225","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A51208","pred":"chebi_id","subj":"T53284","obj":"http://purl.obolibrary.org/obo/CHEBI_46629"},{"id":"A70131","pred":"chebi_id","subj":"T68087","obj":"http://purl.obolibrary.org/obo/CHEBI_32875"},{"id":"A94985","pred":"chebi_id","subj":"T68087","obj":"http://purl.obolibrary.org/obo/CHEBI_29309"},{"id":"A54864","pred":"chebi_id","subj":"T34247","obj":"http://purl.obolibrary.org/obo/CHEBI_26308"},{"id":"A57880","pred":"chebi_id","subj":"T10126","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A9308","pred":"chebi_id","subj":"T17616","obj":"http://purl.obolibrary.org/obo/CHEBI_23019"},{"id":"A5749","pred":"chebi_id","subj":"T42313","obj":"http://purl.obolibrary.org/obo/CHEBI_30359"},{"id":"A23904","pred":"chebi_id","subj":"T23058","obj":"http://purl.obolibrary.org/obo/CHEBI_32772"},{"id":"A52043","pred":"chebi_id","subj":"T23058","obj":"http://purl.obolibrary.org/obo/CHEBI_44520"},{"id":"A59044","pred":"chebi_id","subj":"T46947","obj":"http://purl.obolibrary.org/obo/CHEBI_16881"},{"id":"A91171","pred":"chebi_id","subj":"T8538","obj":"http://purl.obolibrary.org/obo/CHEBI_49637"},{"id":"A25059","pred":"chebi_id","subj":"T48591","obj":"http://purl.obolibrary.org/obo/CHEBI_35581"},{"id":"A17319","pred":"chebi_id","subj":"T47040","obj":"http://purl.obolibrary.org/obo/CHEBI_23004"},{"id":"A8935","pred":"chebi_id","subj":"T47040","obj":"http://purl.obolibrary.org/obo/CHEBI_37622"},{"id":"A8064","pred":"chebi_id","subj":"T81598","obj":"http://purl.obolibrary.org/obo/CHEBI_39282"},{"id":"A44620","pred":"chebi_id","subj":"T54246","obj":"http://purl.obolibrary.org/obo/CHEBI_30512"},{"id":"A28199","pred":"chebi_id","subj":"T54246","obj":"http://purl.obolibrary.org/obo/CHEBI_9141"},{"subj":"T31599","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T89775","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T65814","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T51895","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T17086","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T87780","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T18055","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T38903","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T38323","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T35868","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T54851","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T25452","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T96709","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T78225","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T53284","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T68087","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T34247","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T10126","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T17616","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T42313","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T23058","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T46947","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T8538","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T48591","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T47040","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T81598","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T54246","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T616","span":{"begin":82,"end":143},"obj":"Sentence"},{"id":"T617","span":{"begin":145,"end":292},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T616","pred":"source","obj":"LitCovid-sentences"},{"subj":"T617","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"2028","span":{"begin":104,"end":114},"obj":"Chemical"},{"id":"2029","span":{"begin":82,"end":86},"obj":"Disease"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"attributes":[{"subj":"2028","pred":"source","obj":"LitCovid-PubTator"},{"subj":"2029","pred":"source","obj":"LitCovid-PubTator"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-CLO","color":"#ec9793","default":true},{"id":"LitCovid-PD-CHEBI","color":"#93a9ec"},{"id":"LitCovid-sentences","color":"#c3ec93"},{"id":"LitCovid-PubTator","color":"#ec93dd"}]}]}}