PMC:7571312 / 103841-105144 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T2 535-538 Body_part denotes gum http://purl.org/sig/ont/fma/fma59762

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T26 518-519 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 535-538 http://www.ebi.ac.uk/efo/EFO_0001925 denotes gum
T28 1156-1158 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T29 1192-1197 http://purl.obolibrary.org/obo/CLO_0007706 denotes M + H

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T28369 20-23 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T12835 54-60 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T80677 61-67 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T17859 75-82 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T7065 83-96 Chemical denotes 1H-indol-2-yl http://purl.obolibrary.org/obo/CHEBI_51611
T92099 83-85 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T43403 97-105 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T51598 109-126 Chemical denotes phenylalaninamide http://purl.obolibrary.org/obo/CHEBI_21371
T51479 209-216 Chemical denotes hydroxy http://purl.obolibrary.org/obo/CHEBI_43176
T4347 219-222 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T40276 253-259 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T95406 260-266 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T22791 267-272 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T65875 273-281 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T87134 283-296 Chemical denotes 3-methylbutyl http://purl.obolibrary.org/obo/CHEBI_30359
T13948 300-307 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T99354 308-317 Chemical denotes 1H-indole http://purl.obolibrary.org/obo/CHEBI_16881
T82374 308-310 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T58026 311-317 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_35581
T74351 320-331 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T67119 359-365 Chemical denotes chloro http://purl.obolibrary.org/obo/CHEBI_47853
T9916 368-371 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T4652 402-408 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T96724 409-415 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T40234 423-430 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T30605 431-444 Chemical denotes 1H-indol-2-yl http://purl.obolibrary.org/obo/CHEBI_51611
T90926 431-433 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T79164 445-453 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T74733 457-474 Chemical denotes phenylalaninamide http://purl.obolibrary.org/obo/CHEBI_21371
T42744 613-621 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T26550 622-637 Chemical denotes dichloromethane http://purl.obolibrary.org/obo/CHEBI_15767
T14781 703-705 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T83129 720-724 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T66087 753-755 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T96471 799-801 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T95809 844-846 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T63196 896-898 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T68027 922-924 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T38372 948-950 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T51455 974-976 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T5413 1000-1002 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T65537 1014-1016 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T28177 1028-1030 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T11461 1094-1096 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T25377 1113-1115 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T7201 1132-1134 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T7039 1156-1158 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T78859 1234-1237 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T577 0-131 Sentence denotes N-((1S)-3-Hydroxy-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)-N-[(4-methoxy-1H-indol-2-yl)carbonyl]-l-phenylalaninamide (42)
T578 132-539 Sentence denotes Following the procedure described for the preparation of N-((1S)-1-{[((1S)-3-hydroxy-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}-3-methylbutyl)-4-methoxy-1H-indole-2-carboxamide but substituting N-((1S)-3-chloro-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)-N-[(4-methoxy-1H-indol-2-yl)carbonyl]-l-phenylalaninamide and making noncritical variations provided a crude greenish gum.
T579 540-702 Sentence denotes This material was purified by Biotage flash chromatography, eluting with methanol/dichloromethane to afford the title compound as an off-white solid, 123 mg, 44%.
T580 703-1267 Sentence denotes 1H NMR (400 MHz, DMSO-d6) δ 11.50 (d, J = 2.0 Hz, 1H), 8.58 (dd, J = 8.2, 3.9 Hz, 2H), 7.63 (s, 1H), 7.35–7.43 (m, 2H), 7.31 (d, J = 1.8 Hz, 1H), 7.27 (t, J = 7.6 Hz, 2H), 7.17 (t, J = 7.3 Hz, 1H), 7.08 (t, J = 8.0 Hz, 1H), 6.98 (d, J = 8.1 Hz, 1H), 6.48 (d, J = 7.8 Hz, 1H), 5.06 (t, J = 6.1 Hz, 1H), 4.72 (m, 1H), 4.48 (m, 1H), 4.16 (m, 2H), 3.89 (s, 3H), 2.97–3.18 (m, 4H), 2.24–2.36 (m, 1H), 2.04–2.18 (m, 1H), 1.88–2.01 (m, 1H), 1.55–1.76 (m, 2H); MS (APCI+) for C27H30N4O6m/z 507.1 (M + H)+; anal. calcd for C27H30N4O6· 1.25 H2O: C, 61.29; H, 6.19; N, 10.59.
T581 1268-1303 Sentence denotes Found: C, 61.37; H, 6.06; N, 10.49.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1906 613-621 Chemical denotes methanol MESH:D000432
1907 622-637 Chemical denotes dichloromethane MESH:D008752
1908 1217-1227 Chemical denotes C27H30N4O6
1909 1234-1237 Chemical denotes H2O
1910 1239-1240 Chemical denotes C MESH:D002244
1911 1258-1259 Chemical denotes N MESH:D009584
1912 1275-1276 Chemical denotes C MESH:D002244
1913 1294-1295 Chemical denotes N MESH:D009584