PMC:7565665 / 79265-80304 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T452","span":{"begin":675,"end":682},"obj":"Body_part"},{"id":"T453","span":{"begin":708,"end":712},"obj":"Body_part"},{"id":"T454","span":{"begin":831,"end":835},"obj":"Body_part"}],"attributes":[{"id":"A452","pred":"fma_id","subj":"T452","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A453","pred":"fma_id","subj":"T453","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A454","pred":"fma_id","subj":"T454","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T116","span":{"begin":708,"end":712},"obj":"Body_part"},{"id":"T117","span":{"begin":831,"end":835},"obj":"Body_part"}],"attributes":[{"id":"A116","pred":"uberon_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A117","pred":"uberon_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T527","span":{"begin":705,"end":707},"obj":"Disease"},{"id":"T528","span":{"begin":708,"end":720},"obj":"Disease"},{"id":"T529","span":{"begin":819,"end":844},"obj":"Disease"},{"id":"T530","span":{"begin":1003,"end":1005},"obj":"Disease"}],"attributes":[{"id":"A527","pred":"mondo_id","subj":"T527","obj":"http://purl.obolibrary.org/obo/MONDO_0009061"},{"id":"A528","pred":"mondo_id","subj":"T528","obj":"http://purl.obolibrary.org/obo/MONDO_0005275"},{"id":"A529","pred":"mondo_id","subj":"T529","obj":"http://purl.obolibrary.org/obo/MONDO_0002267"},{"id":"A530","pred":"mondo_id","subj":"T530","obj":"http://purl.obolibrary.org/obo/MONDO_0017319"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T884","span":{"begin":670,"end":674},"obj":"http://purl.obolibrary.org/obo/PR_000001044"},{"id":"T885","span":{"begin":708,"end":712},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T886","span":{"begin":708,"end":712},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T887","span":{"begin":831,"end":835},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T888","span":{"begin":831,"end":835},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T889","span":{"begin":852,"end":853},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T890","span":{"begin":913,"end":920},"obj":"http://purl.obolibrary.org/obo/CLO_0009985"},{"id":"T891","span":{"begin":1006,"end":1009},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T90594","span":{"begin":16,"end":18},"obj":"Chemical"},{"id":"T32793","span":{"begin":222,"end":224},"obj":"Chemical"},{"id":"T6664","span":{"begin":589,"end":591},"obj":"Chemical"},{"id":"T36631","span":{"begin":675,"end":682},"obj":"Chemical"},{"id":"T14237","span":{"begin":722,"end":724},"obj":"Chemical"},{"id":"T21034","span":{"begin":775,"end":779},"obj":"Chemical"},{"id":"T252","span":{"begin":846,"end":848},"obj":"Chemical"}],"attributes":[{"id":"A34460","pred":"chebi_id","subj":"T90594","obj":"http://purl.obolibrary.org/obo/CHEBI_73825"},{"id":"A87535","pred":"chebi_id","subj":"T32793","obj":"http://purl.obolibrary.org/obo/CHEBI_73825"},{"id":"A288","pred":"chebi_id","subj":"T6664","obj":"http://purl.obolibrary.org/obo/CHEBI_73825"},{"id":"A29222","pred":"chebi_id","subj":"T36631","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A12610","pred":"chebi_id","subj":"T14237","obj":"http://purl.obolibrary.org/obo/CHEBI_73825"},{"id":"A82254","pred":"chebi_id","subj":"T21034","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A73426","pred":"chebi_id","subj":"T252","obj":"http://purl.obolibrary.org/obo/CHEBI_73825"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1895","span":{"begin":670,"end":674},"obj":"Gene"},{"id":"1896","span":{"begin":900,"end":907},"obj":"Gene"},{"id":"1897","span":{"begin":960,"end":971},"obj":"Species"},{"id":"1898","span":{"begin":705,"end":720},"obj":"Disease"},{"id":"1899","span":{"begin":831,"end":844},"obj":"Disease"}],"attributes":[{"id":"A1895","pred":"tao:has_database_id","subj":"1895","obj":"Gene:1080"},{"id":"A1896","pred":"tao:has_database_id","subj":"1896","obj":"Gene:57449"},{"id":"A1897","pred":"tao:has_database_id","subj":"1897","obj":"Tax:12814"},{"id":"A1898","pred":"tao:has_database_id","subj":"1898","obj":"MESH:D003550"},{"id":"A1899","pred":"tao:has_database_id","subj":"1899","obj":"MESH:D008171"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T219","span":{"begin":708,"end":720},"obj":"Phenotype"},{"id":"T220","span":{"begin":819,"end":844},"obj":"Phenotype"}],"attributes":[{"id":"A219","pred":"hp_id","subj":"T219","obj":"http://purl.obolibrary.org/obo/HP_0002088"},{"id":"A220","pred":"hp_id","subj":"T220","obj":"http://purl.obolibrary.org/obo/HP_0006536"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1005","span":{"begin":75,"end":81},"obj":"http://purl.obolibrary.org/obo/GO_0060361"},{"id":"T1006","span":{"begin":670,"end":674},"obj":"http://purl.obolibrary.org/obo/GO_0005260"},{"id":"T1007","span":{"begin":675,"end":693},"obj":"http://purl.obolibrary.org/obo/GO_0016485"},{"id":"T1008","span":{"begin":939,"end":950},"obj":"http://purl.obolibrary.org/obo/GO_0006412"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}

{"project":"LitCovid-sentences","denotations":[{"id":"T420","span":{"begin":0,"end":15},"obj":"Sentence"},{"id":"T421","span":{"begin":16,"end":225},"obj":"Sentence"},{"id":"T422","span":{"begin":226,"end":377},"obj":"Sentence"},{"id":"T423","span":{"begin":379,"end":386},"obj":"Sentence"},{"id":"T424","span":{"begin":387,"end":565},"obj":"Sentence"},{"id":"T425","span":{"begin":567,"end":588},"obj":"Sentence"},{"id":"T426","span":{"begin":589,"end":721},"obj":"Sentence"},{"id":"T427","span":{"begin":722,"end":845},"obj":"Sentence"},{"id":"T428","span":{"begin":846,"end":1039},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Acknowledgments\nNV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV. We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.\n\nFunding\nThe funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.\n\nConflicts of Interest\nNV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease. NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases. NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests."}