PMC:7565665 / 64567-64838 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T426","span":{"begin":178,"end":180},"obj":"Body_part"},{"id":"T427","span":{"begin":260,"end":265},"obj":"Body_part"}],"attributes":[{"id":"A426","pred":"fma_id","subj":"T426","obj":"http://purl.org/sig/ont/fma/fma284995"},{"id":"A427","pred":"fma_id","subj":"T427","obj":"http://purl.org/sig/ont/fma/fma68877"}],"text":"Similarly, our recent studies validated cysteamine’s extensive repertoire of protective mechanisms in CF, and demonstrated for the first time that cysteamine was able to control CS-induced lipophagy impairment and the resulting ceramide accumulation in murine lungs [22]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T465","span":{"begin":102,"end":104},"obj":"Disease"}],"attributes":[{"id":"A465","pred":"mondo_id","subj":"T465","obj":"http://purl.obolibrary.org/obo/MONDO_0009061"}],"text":"Similarly, our recent studies validated cysteamine’s extensive repertoire of protective mechanisms in CF, and demonstrated for the first time that cysteamine was able to control CS-induced lipophagy impairment and the resulting ceramide accumulation in murine lungs [22]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T762","span":{"begin":260,"end":265},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T763","span":{"begin":267,"end":269},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"}],"text":"Similarly, our recent studies validated cysteamine’s extensive repertoire of protective mechanisms in CF, and demonstrated for the first time that cysteamine was able to control CS-induced lipophagy impairment and the resulting ceramide accumulation in murine lungs [22]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T17243","span":{"begin":147,"end":157},"obj":"Chemical"},{"id":"T137","span":{"begin":178,"end":180},"obj":"Chemical"},{"id":"T8987","span":{"begin":228,"end":236},"obj":"Chemical"}],"attributes":[{"id":"A72621","pred":"chebi_id","subj":"T17243","obj":"http://purl.obolibrary.org/obo/CHEBI_17141"},{"id":"A87014","pred":"chebi_id","subj":"T17243","obj":"http://purl.obolibrary.org/obo/CHEBI_58029"},{"id":"A73529","pred":"chebi_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/CHEBI_73462"},{"id":"A28340","pred":"chebi_id","subj":"T8987","obj":"http://purl.obolibrary.org/obo/CHEBI_17761"},{"id":"A58129","pred":"chebi_id","subj":"T8987","obj":"http://purl.obolibrary.org/obo/CHEBI_52639"}],"text":"Similarly, our recent studies validated cysteamine’s extensive repertoire of protective mechanisms in CF, and demonstrated for the first time that cysteamine was able to control CS-induced lipophagy impairment and the resulting ceramide accumulation in murine lungs [22]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1610","span":{"begin":253,"end":259},"obj":"Species"},{"id":"1614","span":{"begin":40,"end":50},"obj":"Chemical"},{"id":"1615","span":{"begin":147,"end":157},"obj":"Chemical"},{"id":"1616","span":{"begin":228,"end":236},"obj":"Chemical"}],"attributes":[{"id":"A1610","pred":"tao:has_database_id","subj":"1610","obj":"Tax:10090"},{"id":"A1614","pred":"tao:has_database_id","subj":"1614","obj":"MESH:D003543"},{"id":"A1615","pred":"tao:has_database_id","subj":"1615","obj":"MESH:D003543"},{"id":"A1616","pred":"tao:has_database_id","subj":"1616","obj":"MESH:D002518"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Similarly, our recent studies validated cysteamine’s extensive repertoire of protective mechanisms in CF, and demonstrated for the first time that cysteamine was able to control CS-induced lipophagy impairment and the resulting ceramide accumulation in murine lungs [22]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T865","span":{"begin":189,"end":198},"obj":"http://purl.obolibrary.org/obo/GO_0061724"}],"text":"Similarly, our recent studies validated cysteamine’s extensive repertoire of protective mechanisms in CF, and demonstrated for the first time that cysteamine was able to control CS-induced lipophagy impairment and the resulting ceramide accumulation in murine lungs [22]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T334","span":{"begin":0,"end":271},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Similarly, our recent studies validated cysteamine’s extensive repertoire of protective mechanisms in CF, and demonstrated for the first time that cysteamine was able to control CS-induced lipophagy impairment and the resulting ceramide accumulation in murine lungs [22]."}