PMC:7565665 / 62286-62549 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T416","span":{"begin":150,"end":158},"obj":"Body_part"},{"id":"T417","span":{"begin":198,"end":200},"obj":"Body_part"}],"attributes":[{"id":"A416","pred":"fma_id","subj":"T416","obj":"http://purl.org/sig/ont/fma/fma63836"},{"id":"A417","pred":"fma_id","subj":"T417","obj":"http://purl.org/sig/ont/fma/fma284995"}],"text":"Apart from cysteamine and GSNO, we also tested the potential of other FDA-approved autophagy-inducing drugs, such as gemfibrozil (GEM), which induces lysosome formation, and fisetin, in controlling CS-induced autophagy dysfunction and hampered pathogen clearance."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T737","span":{"begin":40,"end":46},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T738","span":{"begin":150,"end":158},"obj":"http://purl.obolibrary.org/obo/GO_0005764"}],"text":"Apart from cysteamine and GSNO, we also tested the potential of other FDA-approved autophagy-inducing drugs, such as gemfibrozil (GEM), which induces lysosome formation, and fisetin, in controlling CS-induced autophagy dysfunction and hampered pathogen clearance."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T109","span":{"begin":11,"end":21},"obj":"Chemical"},{"id":"T111","span":{"begin":26,"end":30},"obj":"Chemical"},{"id":"T112","span":{"begin":102,"end":107},"obj":"Chemical"},{"id":"T54131","span":{"begin":117,"end":128},"obj":"Chemical"},{"id":"T17954","span":{"begin":130,"end":133},"obj":"Chemical"},{"id":"T48946","span":{"begin":174,"end":181},"obj":"Chemical"},{"id":"T116","span":{"begin":198,"end":200},"obj":"Chemical"}],"attributes":[{"id":"A99217","pred":"chebi_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/CHEBI_17141"},{"id":"A71432","pred":"chebi_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/CHEBI_58029"},{"id":"A30980","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_50091"},{"id":"A74383","pred":"chebi_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A34654","pred":"chebi_id","subj":"T54131","obj":"http://purl.obolibrary.org/obo/CHEBI_5296"},{"id":"A96669","pred":"chebi_id","subj":"T17954","obj":"http://purl.obolibrary.org/obo/CHEBI_5296"},{"id":"A92604","pred":"chebi_id","subj":"T48946","obj":"http://purl.obolibrary.org/obo/CHEBI_42567"},{"id":"A79532","pred":"chebi_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/CHEBI_73462"}],"text":"Apart from cysteamine and GSNO, we also tested the potential of other FDA-approved autophagy-inducing drugs, such as gemfibrozil (GEM), which induces lysosome formation, and fisetin, in controlling CS-induced autophagy dysfunction and hampered pathogen clearance."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1565","span":{"begin":11,"end":21},"obj":"Chemical"},{"id":"1566","span":{"begin":26,"end":30},"obj":"Chemical"},{"id":"1567","span":{"begin":117,"end":128},"obj":"Chemical"},{"id":"1568","span":{"begin":130,"end":133},"obj":"Chemical"}],"attributes":[{"id":"A1565","pred":"tao:has_database_id","subj":"1565","obj":"MESH:D003543"},{"id":"A1567","pred":"tao:has_database_id","subj":"1567","obj":"MESH:D015248"},{"id":"A1568","pred":"tao:has_database_id","subj":"1568","obj":"MESH:D015248"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Apart from cysteamine and GSNO, we also tested the potential of other FDA-approved autophagy-inducing drugs, such as gemfibrozil (GEM), which induces lysosome formation, and fisetin, in controlling CS-induced autophagy dysfunction and hampered pathogen clearance."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T836","span":{"begin":83,"end":92},"obj":"http://purl.obolibrary.org/obo/GO_0016236"},{"id":"T837","span":{"begin":83,"end":92},"obj":"http://purl.obolibrary.org/obo/GO_0006914"},{"id":"T838","span":{"begin":159,"end":168},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T839","span":{"begin":209,"end":218},"obj":"http://purl.obolibrary.org/obo/GO_0016236"},{"id":"T840","span":{"begin":209,"end":218},"obj":"http://purl.obolibrary.org/obo/GO_0006914"}],"text":"Apart from cysteamine and GSNO, we also tested the potential of other FDA-approved autophagy-inducing drugs, such as gemfibrozil (GEM), which induces lysosome formation, and fisetin, in controlling CS-induced autophagy dysfunction and hampered pathogen clearance."}

{"project":"LitCovid-sentences","denotations":[{"id":"T323","span":{"begin":0,"end":263},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Apart from cysteamine and GSNO, we also tested the potential of other FDA-approved autophagy-inducing drugs, such as gemfibrozil (GEM), which induces lysosome formation, and fisetin, in controlling CS-induced autophagy dysfunction and hampered pathogen clearance."}