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PMC:7565665 / 61732-62116 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T411 91-93 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T412 98-100 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T413 138-147 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T414 283-291 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T453 33-37 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T454 38-47 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T731 19-20 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T732 178-182 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T733 360-366 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T23686 91-93 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T105 98-100 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T44313 367-371 Chemical denotes GSNO http://purl.obolibrary.org/obo/CHEBI_50091

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1551 178-182 Gene denotes CFTR Gene:12638
1557 48-54 Species denotes murine Tax:10090
1563 367-371 Chemical denotes GSNO
1574 33-47 Disease denotes COPD-emphysema MESH:D029424

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T202 33-37 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T203 38-47 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T828 167-176 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T829 178-182 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T830 193-205 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T831 241-250 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T832 241-250 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T321 0-384 Sentence denotes Furthermore, using a preclinical COPD-emphysema murine model, we demonstrated that chronic CS (Ch-CS) induced an increase in inflammatory cytokines in BALF, aggresome formation, CFTR-aggresome localization, oxidative/nitrosative stress, and apoptosis, and the emphysematous changes (alveolar airspace enlargement) were significantly improved by augmenting the airway GSNO levels [62].