PMC:7565665 / 52977-53183 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T632","span":{"begin":34,"end":35},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T633","span":{"begin":74,"end":78},"obj":"http://purl.obolibrary.org/obo/PR_000001044"},{"id":"T634","span":{"begin":129,"end":130},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T635","span":{"begin":172,"end":184},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"}],"text":"As such, ceramide accumulation as a result of either inherent or acquired CFTR dysfunction leads to autophagy impairment causing a diminished immune response and bacterial colonization or viral replication."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T14738","span":{"begin":9,"end":17},"obj":"Chemical"}],"attributes":[{"id":"A9960","pred":"chebi_id","subj":"T14738","obj":"http://purl.obolibrary.org/obo/CHEBI_17761"},{"id":"A2793","pred":"chebi_id","subj":"T14738","obj":"http://purl.obolibrary.org/obo/CHEBI_52639"}],"text":"As such, ceramide accumulation as a result of either inherent or acquired CFTR dysfunction leads to autophagy impairment causing a diminished immune response and bacterial colonization or viral replication."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1315","span":{"begin":9,"end":17},"obj":"Chemical"},{"id":"1318","span":{"begin":74,"end":90},"obj":"Disease"}],"attributes":[{"id":"A1315","pred":"tao:has_database_id","subj":"1315","obj":"MESH:D002518"},{"id":"A1318","pred":"tao:has_database_id","subj":"1318","obj":"MESH:D009461"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"As such, ceramide accumulation as a result of either inherent or acquired CFTR dysfunction leads to autophagy impairment causing a diminished immune response and bacterial colonization or viral replication."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T716","span":{"begin":74,"end":78},"obj":"http://purl.obolibrary.org/obo/GO_0005260"},{"id":"T717","span":{"begin":100,"end":109},"obj":"http://purl.obolibrary.org/obo/GO_0016236"},{"id":"T718","span":{"begin":100,"end":109},"obj":"http://purl.obolibrary.org/obo/GO_0006914"},{"id":"T719","span":{"begin":142,"end":157},"obj":"http://purl.obolibrary.org/obo/GO_0006955"},{"id":"T720","span":{"begin":188,"end":205},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T721","span":{"begin":188,"end":205},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"As such, ceramide accumulation as a result of either inherent or acquired CFTR dysfunction leads to autophagy impairment causing a diminished immune response and bacterial colonization or viral replication."}

{"project":"LitCovid-sentences","denotations":[{"id":"T283","span":{"begin":0,"end":206},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"As such, ceramide accumulation as a result of either inherent or acquired CFTR dysfunction leads to autophagy impairment causing a diminished immune response and bacterial colonization or viral replication."}