PMC:7565665 / 45956-46161 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T316","span":{"begin":29,"end":32},"obj":"Body_part"},{"id":"T317","span":{"begin":40,"end":43},"obj":"Body_part"},{"id":"T318","span":{"begin":48,"end":51},"obj":"Body_part"},{"id":"T319","span":{"begin":69,"end":78},"obj":"Body_part"},{"id":"T320","span":{"begin":193,"end":204},"obj":"Body_part"}],"attributes":[{"id":"A316","pred":"fma_id","subj":"T316","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A317","pred":"fma_id","subj":"T317","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A318","pred":"fma_id","subj":"T318","obj":"http://purl.org/sig/ont/fma/fma84079"},{"id":"A319","pred":"fma_id","subj":"T319","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A320","pred":"fma_id","subj":"T320","obj":"http://purl.org/sig/ont/fma/fma63261"}],"text":"The diminished expression of HLA-DQ and HLA-DR (MHC-II molecules) on monocytes derived from ΔF508-CFTR homozygous CF subjects [166], might explain the impaired pathogen clearance ability of CF macrophages."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T358","span":{"begin":114,"end":116},"obj":"Disease"},{"id":"T359","span":{"begin":190,"end":192},"obj":"Disease"}],"attributes":[{"id":"A358","pred":"mondo_id","subj":"T358","obj":"http://purl.obolibrary.org/obo/MONDO_0009061"},{"id":"A359","pred":"mondo_id","subj":"T359","obj":"http://purl.obolibrary.org/obo/MONDO_0009061"}],"text":"The diminished expression of HLA-DQ and HLA-DR (MHC-II molecules) on monocytes derived from ΔF508-CFTR homozygous CF subjects [166], might explain the impaired pathogen clearance ability of CF macrophages."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T526","span":{"begin":69,"end":78},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T527","span":{"begin":98,"end":102},"obj":"http://purl.obolibrary.org/obo/PR_000001044"}],"text":"The diminished expression of HLA-DQ and HLA-DR (MHC-II molecules) on monocytes derived from ΔF508-CFTR homozygous CF subjects [166], might explain the impaired pathogen clearance ability of CF macrophages."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T244","span":{"begin":33,"end":35},"obj":"Chemical"},{"id":"T245","span":{"begin":44,"end":46},"obj":"Chemical"},{"id":"T246","span":{"begin":52,"end":54},"obj":"Chemical"},{"id":"T247","span":{"begin":55,"end":64},"obj":"Chemical"}],"attributes":[{"id":"A244","pred":"chebi_id","subj":"T244","obj":"http://purl.obolibrary.org/obo/CHEBI_73827"},{"id":"A245","pred":"chebi_id","subj":"T245","obj":"http://purl.obolibrary.org/obo/CHEBI_73445"},{"id":"A246","pred":"chebi_id","subj":"T246","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A247","pred":"chebi_id","subj":"T247","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"}],"text":"The diminished expression of HLA-DQ and HLA-DR (MHC-II molecules) on monocytes derived from ΔF508-CFTR homozygous CF subjects [166], might explain the impaired pathogen clearance ability of CF macrophages."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1136","span":{"begin":98,"end":102},"obj":"Gene"}],"attributes":[{"id":"A1136","pred":"tao:has_database_id","subj":"1136","obj":"Gene:1080"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The diminished expression of HLA-DQ and HLA-DR (MHC-II molecules) on monocytes derived from ΔF508-CFTR homozygous CF subjects [166], might explain the impaired pathogen clearance ability of CF macrophages."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T623","span":{"begin":98,"end":102},"obj":"http://purl.obolibrary.org/obo/GO_0005260"}],"text":"The diminished expression of HLA-DQ and HLA-DR (MHC-II molecules) on monocytes derived from ΔF508-CFTR homozygous CF subjects [166], might explain the impaired pathogen clearance ability of CF macrophages."}

{"project":"LitCovid-sentences","denotations":[{"id":"T242","span":{"begin":0,"end":205},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The diminished expression of HLA-DQ and HLA-DR (MHC-II molecules) on monocytes derived from ΔF508-CFTR homozygous CF subjects [166], might explain the impaired pathogen clearance ability of CF macrophages."}