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PMC:7565665 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 197-205 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T2 225-235 Body_part denotes organelles http://purl.org/sig/ont/fma/fma63832
T3 288-296 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T4 436-444 Body_part denotes lysosome http://purl.org/sig/ont/fma/fma63836
T5 571-575 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T6 705-709 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T7 1025-1033 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T8 1152-1156 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T9 1434-1438 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T10 1608-1612 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T11 1789-1793 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T12 1938-1942 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T13 2213-2219 Body_part denotes mucosa http://purl.org/sig/ont/fma/fma85355
T14 2485-2501 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T15 2496-2501 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T16 2608-2613 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T17 2645-2658 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T18 3049-3053 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T19 3206-3214 Body_part denotes lysosome http://purl.org/sig/ont/fma/fma63836
T20 3852-3859 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T21 3876-3880 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T22 4009-4017 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T23 4048-4055 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T24 4096-4104 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T25 4152-4160 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T26 4245-4253 Body_part denotes lysosome http://purl.org/sig/ont/fma/fma63836
T27 4331-4338 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T28 4367-4377 Body_part denotes organelles http://purl.org/sig/ont/fma/fma63832
T29 4653-4661 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T30 4753-4760 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T31 4823-4844 Body_part denotes endoplasmic reticulum http://purl.org/sig/ont/fma/fma63842
T32 4846-4848 Body_part denotes ER http://purl.org/sig/ont/fma/fma63842
T33 5044-5051 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T34 5960-5968 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T35 6313-6315 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T36 6594-6596 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T37 6657-6661 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T38 6751-6755 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T39 7039-7043 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T40 7622-7627 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T41 8203-8214 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T42 8216-8218 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T43 8232-8236 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T44 8355-8357 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T45 8673-8681 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T46 8741-8745 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T47 9093-9108 Body_part denotes plasma membrane http://purl.org/sig/ont/fma/fma63841
T48 9110-9112 Body_part denotes PM http://purl.org/sig/ont/fma/fma63841
T49 9265-9269 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T50 9313-9317 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T51 9533-9538 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T52 9890-9894 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T53 10235-10240 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T54 10281-10297 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T55 10292-10297 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T56 10299-10310 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T57 10312-10321 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T58 10327-10338 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T59 10460-10465 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T60 10482-10487 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T61 10496-10501 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T62 10514-10532 Body_part denotes regulatory T cells http://purl.org/sig/ont/fma/fma84070
T63 10527-10532 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T64 10549-10554 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T65 10618-10627 Body_part denotes platelets http://purl.org/sig/ont/fma/fma62851
T66 10729-10737 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T67 10793-10797 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T68 10897-10901 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T69 11304-11306 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T70 12309-12313 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T71 12582-12590 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T72 12814-12819 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T73 12911-12922 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T74 13002-13019 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T75 13826-13831 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T76 14401-14412 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T77 14567-14587 Body_part denotes alveolar macrophages http://purl.org/sig/ont/fma/fma83023
T78 14800-14818 Body_part denotes lipopolysaccharide http://purl.org/sig/ont/fma/fma82785
T79 14820-14823 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T80 14913-14916 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T81 14954-14958 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T82 15027-15030 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T83 15054-15058 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T84 15164-15182 Body_part denotes respiratory system http://purl.org/sig/ont/fma/fma7158
T85 15525-15540 Body_part denotes dendritic cells http://purl.org/sig/ont/fma/fma273565
T86 15535-15540 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T87 15552-15561 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T88 15800-15817 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T89 16014-16019 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T90 16091-16095 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T91 16113-16115 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T92 16179-16181 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T93 16359-16361 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T94 16462-16464 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T95 16591-16593 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T96 16647-16655 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T97 16786-16788 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T98 17209-17211 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T99 17315-17317 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T100 17339-17343 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T101 18296-18303 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T102 18365-18378 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T103 18402-18407 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T104 18635-18649 Body_part denotes autophagosomes http://purl.org/sig/ont/fma/fma0326100
T105 18653-18662 Body_part denotes lysosomes http://purl.org/sig/ont/fma/fma63836
T106 19310-19321 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T107 19775-19782 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T108 20052-20063 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T109 20242-20244 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T110 20334-20336 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T111 20513-20515 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T112 20663-20665 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T113 20975-20983 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T114 21190-21192 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T115 21253-21255 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T116 21450-21454 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T117 21472-21478 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T118 21546-21550 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T119 21970-21974 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195
T120 22058-22062 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T121 22442-22445 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T122 22587-22590 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T123 22605-22609 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T124 22667-22670 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T125 22687-22691 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T126 22725-22729 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T127 22746-22755 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852
T128 22811-22820 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T129 22822-22826 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T130 22822-22824 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T131 23125-23128 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T132 23137-23141 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T133 23336-23339 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T134 23354-23358 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T135 23501-23505 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T136 23533-23541 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T137 23638-23642 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T138 23965-23970 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T139 23980-23988 Body_part denotes neonates http://purl.org/sig/ont/fma/fma292381
T140 24142-24146 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T141 24253-24266 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T142 24279-24292 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T143 24309-24322 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T144 24350-24354 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T145 24471-24479 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T146 24942-24946 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T147 25162-25166 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T148 25211-25219 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T149 25445-25448 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T150 25559-25579 Body_part denotes alveolar macrophages http://purl.org/sig/ont/fma/fma83023
T151 25600-25603 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T152 25732-25735 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T153 25775-25784 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T154 25819-25824 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T155 25921-25925 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T156 26136-26139 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T157 26182-26186 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T158 26182-26184 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T159 26207-26211 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T160 26396-26400 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T161 26396-26398 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T162 26475-26479 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T163 26496-26499 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T164 27353-27361 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T165 27400-27404 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T166 27463-27467 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T167 27641-27645 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T168 27746-27752 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T169 27786-27793 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T170 27842-27863 Body_part denotes endoplasmic reticulum http://purl.org/sig/ont/fma/fma63842
T171 27865-27867 Body_part denotes ER http://purl.org/sig/ont/fma/fma63842
T172 27950-27963 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T173 28033-28041 Body_part denotes lysosome http://purl.org/sig/ont/fma/fma63836
T174 28125-28129 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T175 28399-28404 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T176 28742-28746 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T177 30188-30196 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T178 30260-30264 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T179 30634-30638 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T180 30997-31006 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T181 31037-31045 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T182 31132-31137 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T183 31269-31293 Body_part denotes gastrointestinal systems http://purl.org/sig/ont/fma/fma71132
T184 31464-31469 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T185 31480-31493 Body_part denotes organ systems http://purl.org/sig/ont/fma/fma7149
T186 31480-31485 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T187 31575-31579 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T188 32050-32054 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T189 32200-32204 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T190 32205-32212 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T191 32470-32478 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T192 32552-32559 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T193 32560-32590 Body_part denotes microtubule-associated protein http://purl.org/sig/ont/fma/fma67847
T194 32765-32769 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T195 32793-32798 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T196 32820-32828 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T197 32976-32978 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T198 33132-33140 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T199 33192-33196 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T200 33236-33241 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T201 33289-33293 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T202 33487-33489 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T203 33498-33502 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T204 33727-33729 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T205 33760-33767 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T206 34082-34084 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T207 34158-34160 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T208 34204-34209 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T209 34315-34317 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T210 34424-34426 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T211 34759-34765 Body_part denotes dynein http://purl.org/sig/ont/fma/fma62228
T212 34819-34823 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T213 34824-34831 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T214 34947-34963 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T215 34958-34963 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T216 34975-34977 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T217 35030-35043 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T218 35183-35185 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T219 35293-35297 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T220 35333-35338 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T221 35375-35387 Body_part denotes goblet cells http://purl.org/sig/ont/fma/fma13148
T222 35382-35387 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T223 35528-35533 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T224 35550-35552 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T225 35597-35604 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T226 35667-35674 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T227 35735-35743 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T228 35744-35746 Body_part denotes A1 http://purl.org/sig/ont/fma/fma66592
T229 35798-35802 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T230 35871-35876 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T231 35926-35930 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T232 35931-35937 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T233 35970-35972 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T234 36211-36213 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T235 36305-36310 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T236 36473-36477 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T237 36570-36575 Body_part denotes mucus http://purl.org/sig/ont/fma/fma66938
T238 36764-36768 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T239 37359-37370 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T240 37653-37664 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T241 37757-37760 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T242 37841-37852 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T243 37917-37922 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T244 38006-38011 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T245 38173-38184 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T246 38217-38222 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T247 38320-38324 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T248 38494-38498 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T249 38711-38726 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T250 38722-38726 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T251 38907-38922 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T252 38918-38922 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T253 38938-38951 Body_part denotes myofibroblast http://purl.org/sig/ont/fma/fma0326458
T254 39034-39038 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T255 39131-39135 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T256 39272-39284 Body_part denotes neutrophilic http://purl.org/sig/ont/fma/fma62860
T257 39315-39323 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T258 39449-39453 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T259 39501-39509 Body_part denotes collagen http://purl.org/sig/ont/fma/fma63891
T260 39551-39571 Body_part denotes extracellular matrix http://purl.org/sig/ont/fma/fma9672
T261 39652-39656 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T262 39772-39776 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T263 39826-39830 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T264 39930-39938 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T265 39939-39941 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T266 40026-40028 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T267 40140-40144 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T268 40145-40155 Body_part denotes fibroblast http://purl.org/sig/ont/fma/fma63877
T269 40187-40189 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T270 40225-40233 Body_part denotes collagen http://purl.org/sig/ont/fma/fma63891
T271 40273-40278 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T272 40432-40434 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T273 40721-40723 Body_part denotes A2 http://purl.org/sig/ont/fma/fma66595
T274 40735-40739 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T275 40740-40756 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T276 40751-40756 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T277 40885-40889 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T278 41092-41096 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T279 41097-41108 Body_part denotes fibroblasts http://purl.org/sig/ont/fma/fma63877
T280 41198-41202 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T281 41236-41247 Body_part denotes fibroblasts http://purl.org/sig/ont/fma/fma63877
T282 41850-41852 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T283 41928-41933 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T284 42229-42231 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T285 42397-42412 Body_part denotes plasma membrane http://purl.org/sig/ont/fma/fma63841
T286 42414-42416 Body_part denotes PM http://purl.org/sig/ont/fma/fma63841
T287 42514-42516 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T288 42787-42791 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T289 42909-42914 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T290 43435-43448 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T291 43590-43600 Body_part denotes phagosomal http://purl.org/sig/ont/fma/fma83022
T292 43637-43646 Body_part denotes lysosomes http://purl.org/sig/ont/fma/fma63836
T293 43968-43977 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T294 44075-44086 Body_part denotes cytoplasmic http://purl.org/sig/ont/fma/fma66835
T295 44212-44221 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T296 44230-44234 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T297 44230-44232 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T298 44240-44242 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T299 44404-44410 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T300 44919-44923 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T301 44965-44978 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T302 45079-45084 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T303 45100-45105 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T304 45114-45119 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T305 45123-45128 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T306 45130-45141 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T307 45147-45156 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T308 45192-45207 Body_part denotes dendritic cells http://purl.org/sig/ont/fma/fma273565
T309 45202-45207 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T310 45255-45258 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T311 45393-45398 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T312 45402-45405 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T313 45631-45636 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T314 45840-45851 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T315 45903-45912 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T316 45985-45988 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T317 45996-45999 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T318 46004-46007 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T319 46025-46034 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T320 46149-46160 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T321 46366-46377 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T322 46399-46404 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T323 46480-46496 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T324 46491-46496 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T325 46501-46505 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T326 46515-46526 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T327 46634-46645 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T328 46647-46658 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T329 46739-46751 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T330 46739-46743 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T331 46945-46956 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T332 47054-47064 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T333 47129-47133 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T334 47134-47140 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T335 47213-47216 Body_part denotes LPS http://purl.org/sig/ont/fma/fma82785
T336 47273-47280 Body_part denotes histone http://purl.org/sig/ont/fma/fma74413
T337 47481-47491 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T338 47564-47575 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T339 47648-47655 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T340 47846-47856 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T341 48113-48115 Body_part denotes PM http://purl.org/sig/ont/fma/fma63841
T342 48188-48192 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T343 48385-48389 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T344 48486-48490 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T345 49206-49211 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T346 49399-49404 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T347 49695-49697 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T348 49787-49789 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T349 49846-49848 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T350 49857-49868 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T351 49931-49944 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T352 50044-50046 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T353 50315-50319 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T354 50551-50562 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T355 50619-50630 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T356 50730-50741 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T357 50804-50815 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T358 51101-51105 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T359 51396-51404 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T360 51428-51444 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T361 51439-51444 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T362 51540-51545 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T363 51730-51735 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T364 52202-52207 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T365 52388-52390 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T366 52429-52431 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T367 52591-52596 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T368 53239-53243 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T369 53247-53251 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T370 53341-53345 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T371 53481-53485 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195
T372 53631-53635 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T373 53636-53638 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T374 54579-54581 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T375 54623-54631 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T376 54871-54875 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T377 54876-54882 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T378 55164-55166 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T379 55382-55384 Body_part denotes PM http://purl.org/sig/ont/fma/fma63841
T380 55501-55505 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T381 55664-55669 Body_part denotes mucus http://purl.org/sig/ont/fma/fma66938
T382 55949-55951 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T383 56181-56183 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T384 56504-56506 Body_part denotes PM http://purl.org/sig/ont/fma/fma63841
T385 56527-56529 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T386 56845-56847 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T387 56998-57003 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T388 57029-57031 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T389 57243-57245 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T390 57495-57499 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T391 57560-57562 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T392 57861-57865 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T393 58355-58360 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T394 58658-58662 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T395 58791-58795 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195
T396 58925-58929 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T397 59245-59249 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T398 59430-59434 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T399 59516-59520 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T400 59521-59527 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T401 59747-59749 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T402 59801-59803 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T403 60072-60085 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T404 60143-60145 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T405 60248-60252 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T406 60469-60471 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T407 60806-60813 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T408 61294-61298 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T409 61436-61438 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T410 61723-61725 Body_part denotes PM http://purl.org/sig/ont/fma/fma63841
T411 61823-61825 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T412 61830-61832 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T413 61870-61879 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T414 62015-62023 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T415 62251-62253 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T416 62436-62444 Body_part denotes lysosome http://purl.org/sig/ont/fma/fma63836
T417 62484-62486 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T418 62572-62574 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T419 62832-62843 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T420 63024-63026 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T421 63341-63345 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T422 63496-63500 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T423 63626-63630 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T424 63706-63714 Body_part denotes Thymosin http://purl.org/sig/ont/fma/fma67128
T425 63837-63839 Body_part denotes PM http://purl.org/sig/ont/fma/fma63841
T426 64745-64747 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T427 64827-64832 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T428 65364-65374 Body_part denotes fibroblast http://purl.org/sig/ont/fma/fma63877
T429 65403-65428 Body_part denotes alveolar epithelial cells http://purl.org/sig/ont/fma/fma62499
T430 65423-65428 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T431 65487-65489 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T432 65544-65552 Body_part denotes collagen http://purl.org/sig/ont/fma/fma63891
T433 65574-65579 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T434 65737-65741 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T435 67483-67494 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T436 67560-67571 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T437 67615-67626 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T438 68361-68368 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T439 68385-68400 Body_part denotes plasma membrane http://purl.org/sig/ont/fma/fma63841
T440 69724-69729 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T441 71557-71568 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T442 71727-71747 Body_part denotes alveolar macrophages http://purl.org/sig/ont/fma/fma83023
T443 71886-71897 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T444 71967-71978 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T445 72269-72282 Body_part denotes autophagosome http://purl.org/sig/ont/fma/fma0326100
T446 72517-72522 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T447 72682-72693 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T448 73878-73882 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T449 74742-74747 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T450 74907-74909 Body_part denotes A1 http://purl.org/sig/ont/fma/fma66592
T451 76189-76193 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T452 79940-79947 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T453 79973-79977 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T454 80096-80100 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T455 80393-80397 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T456 80534-80539 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T457 80622-80627 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T458 80857-80862 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T459 81078-81093 Body_part denotes plasma membrane http://purl.org/sig/ont/fma/fma63841
T460 81224-81228 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T461 81513-81517 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T462 81695-81699 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T463 81732-81745 Body_part denotes Autophagosome http://purl.org/sig/ont/fma/fma0326100
T464 81746-81755 Body_part denotes lysosomal http://purl.org/sig/ont/fma/fma63836
T465 81944-81948 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T466 82385-82393 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T467 82818-82822 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 571-575 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 705-709 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T3 1152-1156 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T4 1434-1438 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 1608-1612 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T6 1789-1793 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T7 1938-1942 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T8 2213-2219 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T9 2645-2658 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T10 3049-3053 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T11 6657-6661 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T12 6751-6755 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T13 7039-7043 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T14 8232-8236 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T15 8741-8745 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T16 9265-9269 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T17 9890-9894 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T18 10793-10797 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T19 10897-10901 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T20 12309-12313 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T21 13002-13019 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T22 14954-14958 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T23 15054-15058 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T24 15164-15182 Body_part denotes respiratory system http://purl.obolibrary.org/obo/UBERON_0001004
T25 15800-15817 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T26 16091-16095 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T27 17339-17343 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T28 21450-21454 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T29 21472-21478 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T30 21546-21550 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T31 21970-21974 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T32 22058-22062 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T33 22605-22609 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T34 22687-22691 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T35 22725-22729 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T36 23137-23141 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T37 23354-23358 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T38 23501-23505 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T39 23638-23642 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T40 24142-24146 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T41 24350-24354 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T42 24942-24946 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T43 25162-25166 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T44 25921-25925 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T45 26207-26211 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T46 26475-26479 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T47 27400-27404 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T48 27463-27467 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T49 27641-27645 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T50 30260-30264 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T51 30634-30638 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T52 31480-31485 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T53 31575-31579 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T54 32050-32054 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T55 32200-32204 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T56 33192-33196 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T57 33289-33293 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T58 33498-33502 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T59 34230-34236 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T60 34819-34823 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T61 35926-35930 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T62 35931-35937 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T63 36473-36477 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T64 36570-36575 Body_part denotes mucus http://purl.obolibrary.org/obo/UBERON_0000912
T65 36764-36768 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T66 38494-38498 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T67 39034-39038 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T68 39131-39135 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T69 39449-39453 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T70 39652-39656 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T71 39772-39776 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T72 39826-39830 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T73 40140-40144 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T74 40735-40739 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T75 40885-40889 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T76 41092-41096 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T77 42787-42791 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T78 44404-44410 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T79 44919-44923 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T80 44965-44978 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T81 46501-46505 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T82 47129-47133 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T83 47134-47140 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T84 48188-48192 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T85 48385-48389 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T86 48486-48490 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T87 50315-50319 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T88 51101-51105 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T89 53239-53243 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T90 53247-53251 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T91 53341-53345 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T92 53481-53485 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T93 53631-53635 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T94 54871-54875 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T95 54876-54882 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T96 55501-55505 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T97 55664-55669 Body_part denotes mucus http://purl.obolibrary.org/obo/UBERON_0000912
T98 57495-57499 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T99 57861-57865 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T100 58658-58662 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T101 58791-58795 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T102 58925-58929 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T103 59245-59249 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T104 59430-59434 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T105 59516-59520 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T106 59521-59527 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T107 60248-60252 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T108 61294-61298 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T109 63341-63345 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T110 63496-63500 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T111 63626-63630 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T112 65737-65741 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T113 69724-69729 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T114 73878-73882 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T115 76189-76193 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T116 79973-79977 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T117 80096-80100 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T118 80393-80397 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T119 81513-81517 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T120 81944-81948 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T121 82818-82822 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 93-101 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 571-584 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T3 594-631 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T4 614-631 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T5 633-637 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T6 640-655 Disease denotes cystic fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T7 657-659 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T8 662-691 Disease denotes idiopathic pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0008345
T9 673-691 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T10 693-696 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T12 699-716 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T14 710-716 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T15 718-721 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T16 724-759 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T17 730-759 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T18 761-765 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T19 772-796 Disease denotes coronavirus disease-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T20 798-806 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T21 1152-1164 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T22 1265-1280 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T23 1271-1280 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T24 1434-1447 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T25 1498-1513 Disease denotes cystic fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T26 1608-1620 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T27 1789-1802 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T28 1852-1856 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T29 1858-1860 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T30 1862-1865 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T31 1866-1870 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T32 1875-1883 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 1938-1951 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T34 2378-2388 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T35 2975-3012 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T36 2995-3012 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T37 3014-3018 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T38 3021-3036 Disease denotes cystic fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T39 3038-3040 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T40 3043-3060 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T42 3054-3060 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T43 3062-3065 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T44 3068-3103 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T45 3074-3103 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T46 3105-3109 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T47 3116-3140 Disease denotes coronavirus disease-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T48 3142-3150 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 3381-3390 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T50 3714-3716 Disease denotes PN http://purl.obolibrary.org/obo/MONDO_0011405
T51 3909-3911 Disease denotes PN http://purl.obolibrary.org/obo/MONDO_0011405
T52 3948-3951 Disease denotes UPS http://purl.obolibrary.org/obo/MONDO_0002142
T53 4382-4392 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T54 4477-4479 Disease denotes PN http://purl.obolibrary.org/obo/MONDO_0011405
T55 4957-4972 Disease denotes cystic fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T56 5088-5090 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T57 5222-5224 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T58 5329-5331 Disease denotes PN http://purl.obolibrary.org/obo/MONDO_0011405
T59 5416-5442 Disease denotes neurodegenerative diseases http://purl.obolibrary.org/obo/MONDO_0005559
T60 5479-5499 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T61 5508-5510 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T62 5515-5519 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T63 5541-5563 Disease denotes Respiratory infections http://purl.obolibrary.org/obo/MONDO_0024355
T64 5689-5693 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T65 5694-5703 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T66 6006-6010 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T67 6011-6020 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T68 6227-6249 Disease denotes respiratory infections http://purl.obolibrary.org/obo/MONDO_0024355
T69 6489-6499 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T70 6729-6742 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T71 6751-6763 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T72 6851-6861 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T73 6907-6909 Disease denotes PN http://purl.obolibrary.org/obo/MONDO_0011405
T74 7044-7057 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T75 7287-7291 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T76 7292-7301 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T77 7768-7789 Disease denotes Klebsiella pneumoniae http://purl.obolibrary.org/obo/MONDO_0030602
T78 7867-7876 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T79 7882-7902 Disease denotes Chlamydia pneumoniae http://purl.obolibrary.org/obo/MONDO_0025598
T80 8096-8115 Disease denotes viral infections in http://purl.obolibrary.org/obo/MONDO_0005108
T81 8652-8656 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T82 8662-8671 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T83 8716-8720 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T84 8726-8734 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 8741-8753 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T86 8848-8860 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T87 8866-8875 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T88 8910-8912 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T89 8914-8916 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T90 8922-8938 Disease denotes genetic disorder http://purl.obolibrary.org/obo/MONDO_0003847
T91 9161-9163 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T92 9196-9206 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T93 9219-9231 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T94 9310-9312 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T95 9637-9642 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T96 9775-9784 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T97 9788-9790 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T98 9879-9881 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T99 9890-9902 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T100 10255-10265 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T101 10790-10792 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T102 10798-10810 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T103 10902-10912 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T104 11418-11422 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T105 11667-11671 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T106 11826-11828 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T107 11833-11837 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T108 11886-11896 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T109 12091-12093 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T110 12095-12099 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T111 12101-12104 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T112 12105-12109 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T113 12114-12122 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T114 12188-12198 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T115 12203-12221 Disease denotes immune dysfunction http://purl.obolibrary.org/obo/MONDO_0005046
T116 12309-12321 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T117 12394-12415 Disease denotes Respiratory Infection http://purl.obolibrary.org/obo/MONDO_0024355
T118 12406-12415 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T119 12823-12833 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T120 13347-13367 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T121 13438-13450 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T122 13455-13467 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T123 13510-13522 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T124 13527-13539 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T125 13798-13810 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T126 13959-13971 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T127 13998-14022 Disease denotes Streptococcus pneumoniae http://purl.obolibrary.org/obo/MONDO_0005972
T128 14027-14037 Disease denotes pneumoniae http://purl.obolibrary.org/obo/MONDO_0005249
T129 14101-14110 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T130 14148-14157 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T131 14324-14334 Disease denotes pneumoniae http://purl.obolibrary.org/obo/MONDO_0005249
T132 14335-14344 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T133 14497-14506 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T134 14641-14662 Disease denotes Klebsiella pneumoniae http://purl.obolibrary.org/obo/MONDO_0030602
T135 14927-14939 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T136 14959-14965 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T137 15059-15065 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T138 15132-15152 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T139 15320-15329 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T140 15650-15654 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T141 16243-16245 Disease denotes EB http://purl.obolibrary.org/obo/MONDO_0006541
T142 17416-17426 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T143 17486-17496 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T144 17697-17706 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T145 17859-17868 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T146 18041-18074 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T147 18088-18096 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T148 18541-18551 Disease denotes Legionella http://purl.obolibrary.org/obo/MONDO_0005824
T149 18878-18887 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T150 19091-19103 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T151 19221-19233 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T152 19639-19641 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T153 20009-20011 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T154 20163-20165 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T155 20486-20490 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T156 20821-20841 Disease denotes Respiratory Diseases http://purl.obolibrary.org/obo/MONDO_0005087
T157 21030-21040 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T158 21123-21143 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T159 21464-21470 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T160 21546-21559 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T161 21569-21573 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T162 21574-21583 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T163 21602-21631 Disease denotes idiopathic pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0008345
T164 21613-21631 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T165 21633-21636 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T167 21964-21981 Disease denotes Acute Lung Injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T169 21975-21981 Disease denotes Injury http://purl.obolibrary.org/obo/MONDO_0021178
T170 21983-21986 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T171 22052-22069 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T173 22063-22069 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T174 22429-22432 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T175 22447-22467 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T176 22599-22616 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T178 22610-22616 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T179 22621-22633 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T180 22692-22698 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T181 23142-23148 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T182 23348-23367 Disease denotes acute lung injuries http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T184 23506-23512 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T185 23632-23649 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T187 23643-23649 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T188 23797-23800 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T189 23830-23856 Disease denotes bronchopulmonary dysplasia http://purl.obolibrary.org/obo/MONDO_0019091
T190 23858-23861 Disease denotes BPD http://purl.obolibrary.org/obo/MONDO_0001156|http://purl.obolibrary.org/obo/MONDO_0019091
T192 24006-24009 Disease denotes BPD http://purl.obolibrary.org/obo/MONDO_0001156|http://purl.obolibrary.org/obo/MONDO_0019091
T194 24147-24153 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T195 24355-24361 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T196 24533-24536 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T197 24616-24619 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T198 24648-24683 Disease denotes Acute Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T199 24654-24683 Disease denotes Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T200 24685-24689 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T201 24712-24715 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T202 24732-24767 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T203 24738-24767 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T204 24772-24776 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T205 24856-24860 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T206 24899-24903 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T207 25022-25025 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T208 25322-25325 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T209 25326-25330 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T210 25464-25467 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T211 25468-25472 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T212 25869-25872 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T213 25873-25877 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T214 25926-25932 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T215 25959-25963 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T216 26030-26033 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T217 26156-26160 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T218 26511-26514 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T219 26515-26519 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T220 26596-26599 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T221 26600-26604 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T222 26721-26724 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T223 26725-26729 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T224 26860-26864 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T225 26914-26922 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T226 26949-26957 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T227 27223-27231 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T228 27244-27260 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T229 27277-27285 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T230 27308-27316 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T231 27328-27338 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T232 27379-27388 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T233 27453-27457 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T234 27463-27475 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T235 27542-27550 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T236 27632-27640 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T237 27641-27653 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T238 27690-27708 Disease denotes immune dysfunction http://purl.obolibrary.org/obo/MONDO_0005046
T239 27735-27743 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T240 28103-28111 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T241 28272-28280 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T242 28340-28348 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T243 28654-28670 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T244 29019-29027 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T245 29223-29231 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T246 29308-29312 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T247 29401-29409 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T248 29613-29633 Disease denotes rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0008383
T249 29624-29633 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T250 29635-29642 Disease denotes malaria http://purl.obolibrary.org/obo/MONDO_0005136
T251 29822-29830 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T252 29886-29894 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T253 30167-30171 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T254 30177-30186 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T255 30235-30239 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T256 30245-30253 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T257 30260-30272 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T258 30356-30360 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T259 30431-30439 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T260 30442-30452 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T261 30634-30647 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T262 30699-30707 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T263 30791-30799 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T264 30908-30916 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T265 30935-30943 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T266 31142-31146 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T267 31163-31171 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T268 31580-31592 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T269 31698-31707 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T270 31776-31784 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T271 31867-31871 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T272 32055-32061 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T273 32066-32070 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T274 32071-32080 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T275 32218-32222 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T276 32223-32232 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T277 32851-32860 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T278 32937-32941 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T279 32942-32951 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T280 33019-33028 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T281 33213-33217 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T282 33218-33227 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T283 33354-33358 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T284 33359-33368 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T285 33498-33510 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T286 33553-33557 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T287 33558-33567 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T288 34435-34439 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T289 34440-34449 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T290 34657-34661 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T291 34662-34671 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T292 34835-34839 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T293 35435-35444 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T294 35943-35947 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T295 36130-36134 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T296 36374-36378 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T297 36416-36431 Disease denotes Cystic Fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T298 36432-36447 Disease denotes Cystic fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T299 36453-36485 Disease denotes chronic obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0005002
T300 36461-36485 Disease denotes obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0002267
T301 36473-36485 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T302 36515-36525 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T303 36769-36781 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T304 37150-37152 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T305 37268-37270 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T306 37287-37297 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T307 37356-37358 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T308 37421-37423 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T309 37451-37471 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T310 37650-37652 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T311 37838-37840 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T312 37996-37998 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T313 38170-38172 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T314 38473-38475 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T315 38494-38506 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T316 38564-38567 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T318 38568-38571 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T320 38760-38763 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T322 38971-38974 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T324 39657-39663 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T325 39777-39783 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T326 39826-39838 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T327 39952-39955 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T329 40208-40220 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T330 40497-40500 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T332 40885-40897 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T333 41018-41036 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T334 41114-41117 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T336 41232-41235 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T338 41327-41330 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T340 41372-41375 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T342 41666-41669 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T344 41948-41950 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T345 42316-42320 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T346 42321-42330 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T347 42582-42586 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T348 42587-42596 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T349 42787-42799 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T350 42906-42908 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T351 43301-43304 Disease denotes LAP http://purl.obolibrary.org/obo/MONDO_0007877
T352 43471-43474 Disease denotes LAP http://purl.obolibrary.org/obo/MONDO_0007877
T353 44411-44417 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T354 44742-44754 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T355 44924-44930 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T356 45649-45658 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T357 45797-45807 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T358 46070-46072 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T359 46146-46148 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T360 46308-46310 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T361 46664-46666 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T362 46884-46886 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T363 46942-46944 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T364 47166-47178 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T365 48058-48068 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T366 48148-48166 Disease denotes immune dysfunction http://purl.obolibrary.org/obo/MONDO_0005046
T367 48188-48200 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T368 48344-48364 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T369 48373-48377 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T370 48382-48384 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T371 48644-48660 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T372 48923-48943 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T373 49015-49025 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T374 49240-49260 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T375 49428-49438 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T376 49482-49484 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T377 49647-49657 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T378 50315-50328 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T379 50337-50339 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T380 50344-50348 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T381 50450-50459 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T382 50482-50484 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T383 50850-50859 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T384 50885-50897 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T385 51062-51074 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T386 51138-51154 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T387 51945-51954 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T388 52282-52284 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T389 52332-52336 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T390 52578-52580 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T391 52585-52589 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T392 52763-52783 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T393 53461-53494 Disease denotes Chronic Obstructive Lung Diseases http://purl.obolibrary.org/obo/MONDO_0005002
T394 53806-53813 Disease denotes obesity http://purl.obolibrary.org/obo/MONDO_0011122
T395 53914-53917 Disease denotes RNS http://purl.obolibrary.org/obo/MONDO_0009821|http://purl.obolibrary.org/obo/MONDO_0019105
T397 54249-54253 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T398 54254-54263 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T399 54304-54313 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T400 54317-54321 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T401 54418-54420 Disease denotes EB http://purl.obolibrary.org/obo/MONDO_0006541
T402 54918-54922 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T403 55013-55022 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T404 55489-55513 Disease denotes obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0002267
T405 55501-55513 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T406 55530-55532 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T407 55817-55827 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T408 55887-55889 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T409 56006-56016 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T410 56294-56298 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T411 56400-56404 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T412 56595-56599 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T413 56600-56609 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T414 56709-56711 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T415 56716-56720 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T416 56721-56730 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T417 57104-57108 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T418 57109-57118 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T419 57332-57336 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T420 57337-57346 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T421 57495-57508 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T422 57736-57739 Disease denotes ASM http://purl.obolibrary.org/obo/MONDO_0020333
T423 57858-57860 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T424 57861-57873 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T425 57899-57911 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T426 57970-57979 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T427 58029-58031 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T428 58142-58145 Disease denotes ASM http://purl.obolibrary.org/obo/MONDO_0020333
T429 58221-58224 Disease denotes ASM http://purl.obolibrary.org/obo/MONDO_0020333
T430 58321-58330 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T431 58335-58347 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T432 58364-58366 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T433 58574-58583 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T434 58638-58670 Disease denotes chronic obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0005002
T435 58646-58670 Disease denotes obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0002267
T436 58658-58670 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T437 58771-58804 Disease denotes Chronic Obstructive Lung Diseases http://purl.obolibrary.org/obo/MONDO_0005002
T438 58905-58938 Disease denotes chronic obstructive lung diseases http://purl.obolibrary.org/obo/MONDO_0005002
T439 58973-58983 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T440 59225-59258 Disease denotes chronic obstructive lung diseases http://purl.obolibrary.org/obo/MONDO_0005002
T441 59430-59443 Disease denotes lung diseases http://purl.obolibrary.org/obo/MONDO_0005275
T442 59553-59569 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T443 59847-59856 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T444 60253-60259 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T445 60265-60269 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T446 60270-60279 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T447 61122-61126 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T448 61127-61136 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T449 61282-61306 Disease denotes obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0002267
T450 61294-61306 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T451 61506-61510 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T452 61511-61520 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T453 61765-61769 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T454 61770-61779 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T455 63200-63204 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T456 63205-63214 Disease denotes emphysema http://purl.obolibrary.org/obo/MONDO_0004849
T457 63338-63340 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T458 63341-63353 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T459 63379-63388 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T460 63485-63487 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T461 63501-63511 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T462 63777-63779 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T463 64114-64116 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T464 64280-64282 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T465 64669-64671 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T466 64896-64900 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T467 64905-64907 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T468 64916-64926 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T469 65010-65023 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T470 65024-65028 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T471 65033-65035 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T472 65130-65133 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T474 65241-65244 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T476 65329-65332 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T478 65527-65539 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T479 65717-65749 Disease denotes chronic obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0005002
T480 65725-65749 Disease denotes obstructive lung disease http://purl.obolibrary.org/obo/MONDO_0002267
T481 65737-65749 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T482 65996-66000 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T483 66206-66208 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T484 66430-66432 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T485 67237-67247 Disease denotes cystinosis http://purl.obolibrary.org/obo/MONDO_0016239
T486 67840-67842 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T487 67939-67941 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T488 68014-68027 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T489 68868-68870 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T490 69006-69019 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T491 69020-69022 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T492 69031-69033 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T493 69150-69170 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T494 69291-69301 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T495 69418-69438 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T496 70993-71003 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T497 71214-71224 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T498 71572-71574 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T499 72405-72415 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T500 72496-72498 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T501 72507-72509 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T502 72906-72916 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T503 73170-73189 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T504 73650-73670 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T505 73854-73863 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T506 74139-74155 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T507 74187-74203 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T508 74487-74497 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T509 74521-74532 Disease denotes common cold http://purl.obolibrary.org/obo/MONDO_0005709
T510 74581-74583 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T511 74594-74600 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T512 74615-74619 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T513 75445-75464 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T514 75770-75774 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T515 75795-75816 Disease denotes respiratory infection http://purl.obolibrary.org/obo/MONDO_0024355
T516 75807-75816 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T517 75829-75837 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T518 75973-75981 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T519 76189-76201 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T520 77022-77030 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T521 77386-77394 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T522 77873-77893 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T523 78252-78272 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T524 78282-78298 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T525 78748-78758 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T526 78893-78913 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T527 79970-79972 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T528 79973-79985 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T529 80084-80109 Disease denotes obstructive lung diseases http://purl.obolibrary.org/obo/MONDO_0002267
T530 80268-80270 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T531 80393-80405 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T532 80462-80477 Disease denotes cystic fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T533 80592-80611 Disease denotes bacterial infection http://purl.obolibrary.org/obo/MONDO_0005113
T534 80602-80611 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T535 80676-80713 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T536 80696-80713 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T537 80715-80719 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T538 80751-80766 Disease denotes cystic fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T539 80768-80770 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T540 81327-81337 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T541 81513-81525 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T542 81559-81569 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T543 81582-81598 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T544 81607-81615 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T545 81903-81915 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T546 81944-81956 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T547 82100-82124 Disease denotes coronavirus disease-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T548 82126-82134 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T549 82842-82846 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T550 82848-82850 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T551 82852-82887 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T552 82858-82887 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T553 82889-82893 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T554 82896-82925 Disease denotes idiopathic pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0008345
T555 82907-82925 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T556 82927-82930 Disease denotes IPF http://purl.obolibrary.org/obo/MONDO_0002429|http://purl.obolibrary.org/obo/MONDO_0008345
T558 82937-82945 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 436-444 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosome
T2 571-575 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T3 571-575 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T4 705-709 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T5 705-709 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T6 1152-1156 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T7 1152-1156 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T8 1434-1438 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T9 1434-1438 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T10 1498-1549 http://purl.obolibrary.org/obo/PR_000001044 denotes cystic fibrosis transmembrane conductance regulator
T11 1551-1555 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T12 1608-1612 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T13 1608-1612 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T14 1789-1793 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T15 1789-1793 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T16 1938-1942 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T17 1938-1942 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T18 2131-2132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T19 2206-2212 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T20 2213-2219 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
T21 2223-2224 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T22 2279-2287 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T23 2289-2294 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T24 2389-2398 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T25 2389-2398 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T26 2478-2484 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T27 2485-2495 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T28 2496-2501 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T29 2608-2613 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T30 2645-2658 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T31 2716-2717 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T32 3049-3053 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T33 3049-3053 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T34 3153-3154 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T35 3206-3214 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosome
T36 3225-3226 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T37 3430-3431 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T38 3876-3880 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T39 4069-4070 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T40 4173-4174 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41 4245-4253 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosome
T42 4408-4416 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T43 4421-4428 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T44 4485-4486 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T45 4585-4604 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular components
T46 4914-4915 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 4957-5008 http://purl.obolibrary.org/obo/PR_000001044 denotes cystic fibrosis transmembrane conductance regulator
T48 5010-5014 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T49 5138-5141 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T50 5212-5213 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T51 5269-5271 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T52 5573-5574 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 6657-6661 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T54 6657-6661 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T55 6751-6755 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T56 6751-6755 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T57 6987-6988 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 7039-7043 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T59 7039-7043 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T60 7359-7360 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T61 7455-7458 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T62 7622-7627 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T63 7720-7721 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 7855-7856 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T65 7945-7955 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T66 8120-8127 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T67 8232-8236 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T68 8232-8236 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T69 8291-8296 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T70 8304-8306 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T71 8322-8323 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72 8358-8360 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T73 8401-8406 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T74 8741-8745 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T75 8741-8745 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T76 8920-8921 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T77 8958-8962 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T78 9010-9018 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T79 9039-9043 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T80 9081-9085 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T81 9093-9099 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T82 9100-9108 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T83 9250-9251 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 9265-9269 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T85 9265-9269 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T86 9313-9323 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T87 9370-9374 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T88 9410-9411 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89 9462-9472 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T90 9521-9530 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T91 9531-9538 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T92 9543-9544 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T93 9546-9555 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T94 9581-9582 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 9624-9628 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T96 9680-9681 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T97 9682-9692 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T98 9735-9739 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T99 9759-9762 http://purl.obolibrary.org/obo/CLO_0001547 denotes a P
T100 9805-9806 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T101 9826-9827 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T102 9890-9894 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T103 9890-9894 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T104 9918-9926 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T105 9947-9951 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T106 9974-9975 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 10093-10094 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T108 10161-10165 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T109 10194-10203 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T110 10235-10240 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T111 10274-10280 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T112 10281-10291 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T113 10292-10297 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T114 10312-10321 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T115 10384-10385 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T116 10400-10408 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T117 10409-10413 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T118 10460-10465 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T119 10475-10478 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T120 10475-10478 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T121 10480-10487 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T122 10489-10492 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T123 10494-10501 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T124 10503-10506 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T125 10507-10512 http://purl.obolibrary.org/obo/PR_000001350 denotes FoxP3
T126 10514-10532 http://purl.obolibrary.org/obo/CL_0000815 denotes regulatory T cells
T127 10534-10540 http://purl.obolibrary.org/obo/CL_0000792 denotes T regs
T128 10547-10554 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T129 10561-10562 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T130 10598-10602 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T131 10738-10748 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T132 10772-10773 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T133 10793-10797 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T134 10793-10797 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T135 10872-10873 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T136 10897-10901 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T137 10897-10901 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T138 10937-10938 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T139 10981-10985 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T140 11034-11038 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T141 11113-11123 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T142 11286-11290 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T143 11331-11335 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T144 11336-11344 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T145 11373-11379 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T146 11492-11496 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T147 11747-11750 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T148 11785-11789 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T149 12003-12004 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T150 12139-12144 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T151 12309-12313 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T152 12309-12313 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T153 12543-12562 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular components
T154 12643-12662 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular components
T155 12685-12686 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T156 12814-12819 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T157 12902-12910 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T158 13044-13047 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T159 13194-13201 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T160 13396-13397 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T161 13826-13831 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T162 14158-14167 http://purl.obolibrary.org/obo/CLO_0001658 denotes activates
T163 14250-14253 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T164 14540-14550 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T165 14751-14754 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T166 14787-14796 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T167 14835-14836 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T168 14866-14874 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T169 14892-14900 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T170 14954-14958 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T171 14954-14958 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T172 14988-14998 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T173 15054-15058 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T174 15054-15058 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T175 15164-15182 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory system
T176 15191-15194 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T177 15330-15335 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T178 15411-15416 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T179 15468-15471 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T180 15511-15521 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T181 15525-15540 http://purl.obolibrary.org/obo/CL_0000451 denotes dendritic cells
T182 15615-15620 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T183 16014-16019 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T184 16243-16245 http://purl.obolibrary.org/obo/CLO_0002867 denotes EB
T185 16254-16255 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T186 16427-16437 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T187 16665-16666 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T188 17045-17048 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T189 17142-17144 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T190 17178-17179 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T191 17234-17235 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T192 17339-17343 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T193 17339-17343 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T194 17552-17561 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T195 17552-17561 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T196 17707-17712 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T197 17869-17872 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T198 18149-18157 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T199 18330-18333 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T200 18402-18407 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T201 18532-18539 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T202 18583-18586 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T203 18653-18662 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomes
T204 18676-18684 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T205 18981-18984 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T206 19002-19003 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T207 19024-19032 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T208 19104-19107 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T209 19234-19237 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T210 19253-19261 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T211 19387-19396 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T212 19387-19396 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T213 19413-19419 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T214 19494-19498 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T215 19499-19502 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T216 19584-19588 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T217 19706-19710 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T218 19763-19767 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T219 19908-19912 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T220 19984-19991 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T221 20083-20087 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T222 20135-20139 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T223 20193-20197 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T224 20207-20210 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T225 20299-20303 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T226 20345-20349 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T227 20438-20439 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T228 20560-20564 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T229 20705-20706 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T230 20724-20728 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T231 20842-20843 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T232 21294-21303 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremely
T233 21450-21454 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T234 21450-21454 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T235 21546-21550 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T236 21546-21550 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T237 21970-21974 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T238 21970-21974 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T239 22058-22062 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T240 22058-22062 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T241 22526-22527 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T242 22566-22567 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T243 22605-22609 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T244 22605-22609 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T245 22687-22691 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T246 22687-22691 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T247 22725-22729 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T248 22725-22729 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T249 22997-23007 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T250 23092-23095 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T251 23137-23141 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T252 23137-23141 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T253 23171-23181 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T254 23188-23189 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T255 23190-23199 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T256 23354-23358 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T257 23354-23358 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T258 23501-23505 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T259 23501-23505 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T260 23517-23518 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T261 23638-23642 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T262 23638-23642 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T263 23726-23733 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T264 23889-23890 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T265 23965-23970 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T266 23974-23979 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T267 24080-24081 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T268 24142-24146 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T269 24142-24146 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T270 24350-24354 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T271 24350-24354 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T272 24378-24384 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T273 24788-24791 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T274 24811-24812 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T275 24942-24946 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T276 24942-24946 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T277 25036-25037 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T278 25162-25166 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T279 25162-25166 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T280 25224-25239 http://purl.obolibrary.org/obo/PR_000010543 denotes myeloperoxidase
T281 25241-25244 http://purl.obolibrary.org/obo/PR_000010543 denotes MPO
T282 25273-25274 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T283 25382-25383 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T284 25654-25663 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T285 25693-25696 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T286 25819-25824 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T287 25879-25882 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T288 25921-25925 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T289 25921-25925 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T290 25977-25987 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T291 26004-26007 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T292 26047-26048 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T293 26207-26211 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T294 26207-26211 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T295 26240-26248 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arterial
T296 26240-26248 http://www.ebi.ac.uk/efo/EFO_0000814 denotes arterial
T297 26288-26289 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T298 26338-26348 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T299 26415-26416 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T300 26475-26479 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T301 26475-26479 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T302 26642-26645 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T303 26651-26652 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T304 26969-26972 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T305 27012-27013 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T306 27288-27293 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T307 27400-27404 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T308 27400-27404 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T309 27463-27467 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T310 27463-27467 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T311 27599-27600 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T312 27641-27645 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T313 27641-27645 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T314 27713-27714 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T315 27801-27806 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T316 27910-27915 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T317 28033-28041 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosome
T318 28125-28135 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T319 28157-28162 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T320 28236-28237 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T321 28399-28404 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T322 28560-28567 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T323 28613-28616 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T324 28641-28642 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T325 28700-28705 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T326 28706-28709 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T327 28742-28746 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T328 28863-28864 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T329 29194-29195 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T330 29462-29463 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T331 29846-29849 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T332 30260-30264 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T333 30260-30264 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T334 30296-30297 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T335 30598-30603 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T336 30634-30638 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T337 30634-30638 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T338 30957-30967 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T339 31060-31061 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T340 31132-31137 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T341 31464-31469 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T342 31480-31493 http://purl.obolibrary.org/obo/UBERON_0000467 denotes organ systems
T343 31540-31543 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T344 31575-31579 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T345 31575-31579 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T346 31609-31610 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T347 31709-31712 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T348 31926-31927 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T349 31974-31980 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T350 32050-32054 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T351 32050-32054 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T352 32134-32139 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T353 32194-32199 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T354 32200-32204 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T355 32200-32204 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T356 32793-32798 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T357 33066-33067 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T358 33192-33196 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T359 33192-33196 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T360 33236-33241 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T361 33289-33293 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T362 33289-33293 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T363 33390-33391 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T364 33498-33502 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T365 33498-33502 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T366 33858-33859 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T367 34068-34069 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T368 34127-34128 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T369 34204-34209 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T370 34230-34236 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T371 34284-34287 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T372 34361-34371 http://purl.obolibrary.org/obo/CL_0000234 denotes phagocytic
T373 34639-34640 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T374 34819-34823 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T375 34819-34823 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T376 34947-34957 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T377 34958-34963 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T378 35243-35246 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T379 35293-35303 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T380 35311-35317 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T381 35333-35338 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T382 35346-35352 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T383 35382-35387 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T384 35456-35459 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T385 35528-35533 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T386 35623-35624 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T387 35798-35802 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T388 35831-35832 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T389 35871-35876 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T390 35926-35930 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T391 35926-35930 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T392 35982-35985 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T393 36090-36093 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T394 36120-36121 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T395 36305-36310 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T396 36451-36452 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T397 36473-36477 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T398 36473-36477 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T399 36618-36624 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T400 36673-36674 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T401 36721-36725 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T402 36764-36768 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T403 36764-36768 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T404 36880-36884 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T405 37000-37004 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T406 37392-37402 http://purl.obolibrary.org/obo/CL_0000234 denotes phagocytic
T407 37403-37411 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T408 37525-37526 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T409 37569-37570 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T410 37638-37646 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T411 37917-37922 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T412 37944-37945 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T413 37984-37992 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T414 38006-38011 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T415 38022-38023 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T416 38085-38087 http://purl.obolibrary.org/obo/CLO_0051741 denotes c1
T417 38123-38124 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T418 38217-38222 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T419 38320-38324 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T420 38366-38367 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T421 38443-38444 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T422 38494-38498 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T423 38494-38498 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T424 38575-38576 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T425 38711-38721 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T426 38722-38726 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T427 38744-38745 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T428 38799-38809 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T429 38880-38881 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T430 38907-38917 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T431 38918-38922 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T432 39010-39011 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T433 39034-39038 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T434 39034-39038 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T435 39131-39135 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T436 39131-39135 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T437 39249-39250 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T438 39449-39453 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T439 39449-39453 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T440 39501-39509 http://purl.obolibrary.org/obo/CHEBI_3815 denotes collagen
T441 39572-39577 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T442 39652-39656 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T443 39652-39656 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T444 39772-39776 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T445 39772-39776 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T446 39826-39830 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T447 39826-39830 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T448 39976-39977 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T449 40140-40144 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T450 40140-40144 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T451 40145-40155 http://purl.obolibrary.org/obo/CL_0000057 denotes fibroblast
T452 40225-40233 http://purl.obolibrary.org/obo/CHEBI_3815 denotes collagen
T453 40273-40278 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T454 40418-40419 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T455 40665-40666 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T456 40721-40723 http://purl.obolibrary.org/obo/CLO_0001562 denotes A2
T457 40735-40756 http://purl.obolibrary.org/obo/CL_0000082 denotes lung epithelial cells
T458 40885-40889 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T459 40885-40889 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T460 40949-40959 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T461 41086-41091 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T462 41092-41096 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T463 41092-41096 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T464 41097-41108 http://purl.obolibrary.org/obo/CL_0000057 denotes fibroblasts
T465 41196-41202 http://purl.obolibrary.org/obo/CLO_0001020 denotes a cell
T466 41236-41247 http://purl.obolibrary.org/obo/CL_0000057 denotes fibroblasts
T467 41290-41291 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T468 41703-41707 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T469 41760-41764 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T470 41768-41769 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T471 41804-41812 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T472 41905-41909 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T473 41928-41933 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T474 42020-42024 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T475 42057-42061 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T476 42240-42244 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T477 42385-42389 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T478 42397-42403 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T479 42404-42412 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T480 42449-42453 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T481 42681-42685 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T482 42717-42718 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T483 42787-42791 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T484 42787-42791 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T485 42909-42914 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T486 42933-42942 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T487 42946-42947 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T488 42948-42957 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T489 43046-43050 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T490 43417-43418 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T491 43426-43434 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T492 43601-43609 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T493 43637-43646 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomes
T494 43708-43709 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T495 43897-43907 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T496 44073-44074 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T497 44178-44187 http://purl.obolibrary.org/obo/CLO_0001658 denotes activates
T498 44243-44245 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T499 44278-44288 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T500 44352-44362 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T501 44469-44470 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T502 44506-44516 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T503 44520-44521 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T504 44620-44630 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T505 44783-44784 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T506 44797-44798 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T507 44847-44848 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T508 44885-44895 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T509 44919-44923 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T510 44919-44923 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T511 44965-44978 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T512 45079-45084 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T513 45093-45096 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T514 45098-45105 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T515 45107-45110 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T516 45112-45119 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T517 45121-45128 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T518 45147-45156 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T519 45192-45207 http://purl.obolibrary.org/obo/CL_0000451 denotes dendritic cells
T520 45316-45324 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T521 45386-45389 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T522 45391-45398 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T523 45629-45636 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T524 45688-45689 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T525 45832-45836 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T526 46025-46034 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T527 46054-46058 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T528 46175-46179 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T529 46191-46194 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T530 46225-46229 http://purl.obolibrary.org/obo/CL_0000792 denotes Treg
T531 46252-46253 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T532 46318-46321 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T533 46352-46362 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T534 46399-46404 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T535 46454-46461 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T536 46473-46479 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T537 46480-46505 http://purl.obolibrary.org/obo/CL_0000082 denotes epithelial cells and lung
T538 46568-46569 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T539 46620-46630 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T540 46692-46702 http://purl.obolibrary.org/obo/CL_0000234 denotes phagocytic
T541 46739-46743 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T542 46867-46871 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T543 47046-47049 http://purl.obolibrary.org/obo/PR_000010543 denotes MPO
T544 47075-47077 http://purl.obolibrary.org/obo/CLO_0008149 denotes NE
T545 47129-47133 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T546 47129-47133 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T547 47159-47165 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T548 47225-47228 http://purl.obolibrary.org/obo/PR_000010543 denotes MPO
T549 47399-47403 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T550 47421-47422 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T551 47434-47438 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T552 47459-47460 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T553 47492-47502 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T554 47556-47560 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T555 47781-47785 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T556 47806-47810 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T557 47857-47867 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T558 47876-47886 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T559 47897-47898 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T560 47971-47975 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T561 48101-48105 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T562 48188-48192 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T563 48188-48192 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T564 48240-48244 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T565 48385-48389 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T566 48474-48475 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T567 48486-48490 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T568 48486-48490 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T569 48866-48867 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T570 49092-49093 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T571 49169-49170 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T572 49192-49201 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colonizes
T573 49206-49211 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T574 49372-49376 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T575 49399-49404 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T576 49513-49516 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T577 49722-49726 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T578 49746-49747 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T579 49809-49813 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T580 49831-49832 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T581 49982-49986 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T582 49999-50001 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T583 50069-50073 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T584 50116-50118 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T585 50265-50267 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T586 50277-50281 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T587 50315-50319 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T588 50315-50319 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T589 50420-50421 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T590 50474-50477 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3–5
T591 50531-50534 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T592 50572-50573 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T593 50642-50646 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T594 50658-50666 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T595 50799-50803 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T596 50839-50840 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T597 50945-50949 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T598 50991-50999 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T599 51101-51105 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T600 51101-51105 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T601 51156-51160 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T602 51218-51219 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T603 51257-51261 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T604 51332-51337 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T605 51428-51438 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T606 51439-51444 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T607 51456-51460 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T608 51465-51466 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T609 51540-51545 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T610 51547-51550 http://purl.obolibrary.org/obo/CLO_0054057 denotes 181
T611 51577-51581 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T612 51680-51681 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T613 51725-51729 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T614 51730-51735 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T615 51785-51786 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T616 51819-51823 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T617 51929-51935 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T618 51956-51960 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T619 52133-52137 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T620 52202-52207 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T621 52256-52259 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T622 52299-52303 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T623 52364-52368 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T624 52442-52445 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T625 52530-52532 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T626 52538-52542 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T627 52591-52596 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T628 52859-52863 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T629 52874-52877 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T630 52932-52940 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T631 52962-52969 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T632 53011-53012 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T633 53051-53055 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T634 53106-53107 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T635 53149-53161 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colonization
T636 53205-53209 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T637 53341-53345 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T638 53341-53345 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T639 53413-53417 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T640 53481-53485 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T641 53481-53485 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T642 53536-53543 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T643 53573-53574 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T644 53701-53703 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T645 53862-53870 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T646 53874-53878 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T647 54054-54055 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T648 54418-54420 http://purl.obolibrary.org/obo/CLO_0002867 denotes EB
T649 54510-54519 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T650 54537-54538 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T651 54827-54829 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T652 54865-54870 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T653 54871-54875 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T654 54871-54875 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T655 55033-55035 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T656 55063-55064 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T657 55260-55262 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T658 55309-55310 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T659 55368-55372 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T660 55454-55461 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T661 55501-55505 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T662 55501-55505 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T663 55557-55558 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T664 55582-55586 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T665 55890-55897 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T666 56050-56051 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T667 56068-56076 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T668 56094-56098 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T669 56106-56113 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T670 56150-56154 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T671 56274-56278 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T672 56380-56384 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T673 56492-56496 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T674 56675-56676 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T675 56811-56812 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T676 56833-56837 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T677 56959-56960 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T678 56988-56989 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T679 57009-57013 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T680 57254-57258 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T681 57361-57363 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T682 57404-57408 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T683 57495-57499 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T684 57495-57499 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T685 57711-57715 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T686 57740-57750 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T687 57761-57769 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T688 57793-57795 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T689 57830-57833 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T690 57861-57865 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T691 57861-57865 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T692 58018-58025 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T693 58105-58115 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T694 58169-58177 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T695 58246-58252 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T696 58355-58360 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T697 58424-58428 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T698 58454-58455 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T699 58658-58662 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T700 58658-58662 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T701 58791-58795 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T702 58791-58795 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T703 58835-58839 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T704 58858-58859 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T705 58925-58929 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T706 58925-58929 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T707 59155-59159 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T708 59181-59182 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T709 59245-59249 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T710 59245-59249 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T711 59430-59434 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T712 59430-59434 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T713 59516-59520 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T714 59516-59520 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T715 59684-59688 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T716 59701-59704 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T717 59889-59895 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T718 59949-59950 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T719 60014-60015 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T720 60248-60252 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T721 60248-60252 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T722 60427-60431 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T723 60489-60493 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T724 60582-60588 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T725 61083-61084 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T726 61294-61298 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T727 61294-61298 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T728 61447-61451 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T729 61626-61636 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T730 61711-61715 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T731 61751-61752 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T732 61910-61914 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T733 62092-62098 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T734 62209-62215 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T735 62219-62220 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T736 62262-62266 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T737 62326-62332 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T738 62436-62444 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosome
T739 62738-62740 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T740 62746-62747 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T741 62847-62848 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T742 63095-63097 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T743 63281-63284 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T744 63341-63345 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T745 63341-63345 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T746 63496-63500 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T747 63496-63500 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T748 63626-63630 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T749 63626-63630 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T750 63697-63704 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T751 63825-63829 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T752 63841-63848 http://purl.obolibrary.org/obo/CLO_0009381 denotes 203]. T
T753 63990-63994 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T754 64193-64194 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T755 64254-64257 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T756 64270-64276 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T757 64356-64361 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T758 64405-64406 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T759 64464-64468 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T760 64491-64492 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T761 64520-64524 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T762 64827-64832 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T763 64834-64836 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T764 65072-65075 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T765 65104-65105 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T766 65364-65374 http://purl.obolibrary.org/obo/CL_0000057 denotes fibroblast
T767 65412-65422 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T768 65423-65428 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T769 65446-65447 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T770 65544-65552 http://purl.obolibrary.org/obo/CHEBI_3815 denotes collagen
T771 65574-65579 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T772 65687-65688 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T773 65737-65741 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T774 65737-65741 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T775 66744-66748 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T776 66808-66809 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T777 66857-66858 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T778 66946-66950 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T779 66976-66977 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T780 67037-67040 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T781 67510-67514 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T782 67543-67547 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T783 67699-67700 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T784 67774-67775 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T785 67809-67813 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T786 67883-67895 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colonization
T787 68047-68048 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T788 68107-68108 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T789 68323-68327 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T790 68385-68391 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T791 68392-68400 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T792 68479-68483 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T793 68575-68579 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T794 68619-68623 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T795 68787-68788 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T796 68973-68976 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T797 69192-69196 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T798 69591-69599 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T799 69724-69729 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T800 69724-69729 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T801 69811-69815 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T802 69839-69841 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T803 69919-69923 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T804 70125-70130 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T805 70143-70144 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T806 70237-70241 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T807 70896-70904 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T808 70933-70934 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T809 71138-71146 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T810 71405-71413 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T811 71545-71553 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T812 71635-71636 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T813 71674-71675 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T814 71690-71691 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T815 71808-71809 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T816 71939-71943 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T817 71951-71959 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T818 72028-72031 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T819 72137-72141 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T820 72165-72166 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T821 72196-72197 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T822 72218-72219 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T823 72517-72522 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T824 72556-72557 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T825 72772-72776 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T826 72831-72834 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T827 72846-72850 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T828 73136-73141 http://purl.obolibrary.org/obo/UBERON_0001456 denotes faced
T829 73308-73316 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T830 73399-73400 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T831 73478-73486 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T832 73509-73517 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T833 73576-73583 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Viruses
T834 73593-73594 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T835 73709-73716 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T836 73766-73774 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T837 73785-73793 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T838 73889-73896 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T839 73994-74001 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T840 74032-74039 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T841 74077-74078 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T842 74218-74219 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T843 74251-74256 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T844 74394-74397 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T845 74438-74439 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T846 74540-74541 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T847 74742-74747 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T848 74990-74991 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T849 75150-75153 http://purl.obolibrary.org/obo/CLO_0001195 denotes 219
T850 75336-75337 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T851 75387-75394 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T852 75525-75532 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T853 75607-75614 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T854 75699-75706 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T855 75789-75794 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T856 75910-75922 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T857 75936-75937 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T858 75966-75971 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T859 75984-75987 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T860 76027-76028 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T861 76189-76193 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T862 76189-76193 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T863 76273-76278 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T864 76571-76572 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T865 76822-76823 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T866 76871-76874 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T867 76979-76980 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T868 77036-77039 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T869 77130-77135 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T870 77181-77182 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T871 77211-77216 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T872 77371-77372 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T873 77433-77434 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T874 77493-77494 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T875 77564-77571 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T876 77825-77829 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T877 78119-78127 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T878 78183-78184 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T879 78552-78553 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T880 78640-78641 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T881 79007-79008 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T882 79068-79069 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T883 79222-79223 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T884 79935-79939 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T885 79973-79977 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T886 79973-79977 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T887 80096-80100 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T888 80096-80100 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T889 80117-80118 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T890 80178-80185 http://purl.obolibrary.org/obo/CLO_0009985 denotes focuses
T891 80271-80274 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T892 80393-80397 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T893 80393-80397 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T894 80462-80513 http://purl.obolibrary.org/obo/PR_000001044 denotes cystic fibrosis transmembrane conductance regulator
T895 80515-80519 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T896 80545-80554 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T897 80615-80621 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T898 80622-80627 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T899 80670-80674 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T900 80733-80737 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T901 80745-80749 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T902 80837-80845 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T903 80857-80862 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T904 80903-80910 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T905 80928-80936 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T906 81010-81014 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T907 81078-81084 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T908 81085-81093 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T909 81352-81353 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T910 81513-81517 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T911 81513-81517 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T912 81623-81628 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T913 81695-81699 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T914 81746-81755 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomal
T915 81770-81771 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T916 81808-81815 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T917 81944-81948 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T918 81944-81948 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T919 82354-82358 http://purl.obolibrary.org/obo/PR_000001044 denotes CFTR
T920 82419-82420 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T921 82818-82822 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T922 82818-82822 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 197-205 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T2 288-296 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T3 1025-1033 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T4 3714-3716 Chemical denotes PN http://purl.obolibrary.org/obo/CHEBI_74754
T5 3852-3859 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T6 3909-3911 Chemical denotes PN http://purl.obolibrary.org/obo/CHEBI_74754
T7 4009-4017 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T8 4048-4055 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T9 4096-4104 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T10 4152-4160 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T11 4331-4338 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T12 4351-4357 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T13 4477-4479 Chemical denotes PN http://purl.obolibrary.org/obo/CHEBI_74754
T14 4653-4661 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T15 4663-4669 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T16 4753-4760 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T17 5044-5051 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T18 5329-5331 Chemical denotes PN http://purl.obolibrary.org/obo/CHEBI_74754
T19 6313-6315 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T20 6594-6596 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T21 6907-6909 Chemical denotes PN http://purl.obolibrary.org/obo/CHEBI_74754
T22 8216-8218 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T24 8355-8357 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T26 8628-8633 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T27 9110-9112 Chemical denotes PM http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551
T30 9540-9542 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T33 9620-9622 Chemical denotes WT http://purl.obolibrary.org/obo/CHEBI_141450
T34 9677-9679 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T37 9823-9825 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T40 10076-10079 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T41 10675-10681 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T42 11074-11097 Chemical denotes reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_26523
T43 11083-11089 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T44 11099-11102 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T45 11304-11306 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T46 11438-11441 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T47 12564-12570 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T48 12582-12590 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T49 14800-14818 Chemical denotes lipopolysaccharide http://purl.obolibrary.org/obo/CHEBI_16412
T50 14820-14823 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T53 14847-14852 Chemical denotes toxin http://purl.obolibrary.org/obo/CHEBI_27026
T54 14913-14916 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T57 15027-15030 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T60 16113-16115 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T61 16179-16181 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T62 16243-16245 Chemical denotes EB http://purl.obolibrary.org/obo/CHEBI_53197
T63 16359-16361 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T64 16462-16464 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T65 16591-16593 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T66 16647-16655 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T67 16786-16788 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T68 17191-17200 Chemical denotes biomarker http://purl.obolibrary.org/obo/CHEBI_59163
T69 17209-17211 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T70 17315-17317 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T71 17946-17954 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T72 18187-18189 Chemical denotes TM http://purl.obolibrary.org/obo/CHEBI_55460|http://purl.obolibrary.org/obo/CHEBI_74861
T74 18296-18303 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T75 18699-18703 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T76 19775-19782 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T77 20242-20244 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T78 20334-20336 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T79 20413-20421 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T81 20458-20470 Chemical denotes sphingolipid http://purl.obolibrary.org/obo/CHEBI_26739
T82 20513-20515 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T83 20543-20546 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T84 20663-20665 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T85 21179-21182 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T86 21190-21192 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T87 21244-21247 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T88 21253-21255 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T89 21323-21326 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T90 21369-21376 Chemical denotes oxidant http://purl.obolibrary.org/obo/CHEBI_63248
T91 21377-21388 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T92 21741-21744 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T93 21825-21836 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T94 21837-21842 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T95 22442-22445 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T98 22587-22590 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T101 22667-22670 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T104 22822-22824 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T106 23035-23044 Chemical denotes rapamycin http://purl.obolibrary.org/obo/CHEBI_9168
T107 23125-23128 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T110 23185-23187 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T113 23302-23313 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T114 23314-23319 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T115 23336-23339 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T118 23390-23410 Chemical denotes autophagy inhibitors http://purl.obolibrary.org/obo/CHEBI_88230
T119 23400-23410 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T120 23533-23541 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T121 23723-23725 Chemical denotes WT http://purl.obolibrary.org/obo/CHEBI_141450
T122 24178-24195 Chemical denotes autophagy inducer http://purl.obolibrary.org/obo/CHEBI_138880
T123 24197-24206 Chemical denotes rapamycin http://purl.obolibrary.org/obo/CHEBI_9168
T124 24211-24225 Chemical denotes mTOR inhibitor http://purl.obolibrary.org/obo/CHEBI_68481
T125 24216-24225 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T126 24471-24479 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T127 25092-25101 Chemical denotes rapamycin http://purl.obolibrary.org/obo/CHEBI_9168
T128 25384-25394 Chemical denotes lipoxin A4 http://purl.obolibrary.org/obo/CHEBI_6498|http://purl.obolibrary.org/obo/CHEBI_67026
T130 25384-25391 Chemical denotes lipoxin http://purl.obolibrary.org/obo/CHEBI_6497
T131 25404-25414 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T132 25445-25448 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T135 25600-25603 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T138 25732-25735 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T141 25909-25911 Chemical denotes MV http://purl.obolibrary.org/obo/CHEBI_73616
T142 26136-26139 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T145 26145-26147 Chemical denotes MV http://purl.obolibrary.org/obo/CHEBI_73616
T146 26182-26184 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T148 26371-26373 Chemical denotes MV http://purl.obolibrary.org/obo/CHEBI_73616
T149 26396-26398 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T151 26496-26499 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T154 26500-26502 Chemical denotes MV http://purl.obolibrary.org/obo/CHEBI_73616
T155 27786-27793 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T156 28959-28964 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T157 28966-28976 Chemical denotes spermidine http://purl.obolibrary.org/obo/CHEBI_16610|http://purl.obolibrary.org/obo/CHEBI_57834
T159 29533-29538 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T160 29548-29566 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T161 30151-30156 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T162 32032-32040 Chemical denotes nicotine http://purl.obolibrary.org/obo/CHEBI_18723
T163 32470-32478 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T164 32552-32559 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T165 32583-32590 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T166 32976-32978 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T167 33039-33043 Chemical denotes GOLD http://purl.obolibrary.org/obo/CHEBI_59965
T168 33046-33048 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T169 33487-33489 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T170 33727-33729 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T171 33760-33767 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T172 34051-34066 Chemical denotes ethyl carbamate http://purl.obolibrary.org/obo/CHEBI_17967
T173 34051-34056 Chemical denotes ethyl http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801
T175 34057-34066 Chemical denotes carbamate http://purl.obolibrary.org/obo/CHEBI_13941
T176 34082-34084 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T177 34158-34160 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T178 34315-34317 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T179 34424-34426 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T180 34890-34899 Chemical denotes oligomers http://purl.obolibrary.org/obo/CHEBI_132554
T181 34975-34977 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T182 35123-35132 Chemical denotes oligomers http://purl.obolibrary.org/obo/CHEBI_132554
T183 35183-35185 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T184 35550-35552 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T185 35597-35604 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T186 35667-35674 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T187 35724-35734 Chemical denotes surfactant http://purl.obolibrary.org/obo/CHEBI_35195
T188 35735-35743 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T189 35970-35972 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T190 36211-36213 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T191 36787-36790 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T192 36894-36897 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T193 37712-37721 Chemical denotes bisulfite http://purl.obolibrary.org/obo/CHEBI_17137
T194 37757-37760 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T195 37914-37916 Chemical denotes WT http://purl.obolibrary.org/obo/CHEBI_141450
T196 38982-38991 Chemical denotes Bleomycin http://purl.obolibrary.org/obo/CHEBI_3139
T197 39021-39025 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T198 39113-39122 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T199 39204-39213 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T200 39403-39412 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T201 39633-39642 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T202 39754-39763 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T203 39939-39941 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T205 40026-40028 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T207 40187-40189 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T209 40248-40257 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T210 40364-40383 Chemical denotes autophagy inhibitor http://purl.obolibrary.org/obo/CHEBI_88230
T211 40374-40383 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T212 40432-40434 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T214 40685-40694 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T215 40928-40934 Chemical denotes torin1 http://purl.obolibrary.org/obo/CHEBI_84327
T216 41000-41009 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T217 41850-41852 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T218 42100-42103 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T219 42229-42231 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T220 42289-42297 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T222 42414-42416 Chemical denotes PM http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551
T225 42464-42484 Chemical denotes S-nitrosoglutathione http://purl.obolibrary.org/obo/CHEBI_145544|http://purl.obolibrary.org/obo/CHEBI_50091
T227 42486-42490 Chemical denotes GSNO http://purl.obolibrary.org/obo/CHEBI_50091
T228 42514-42516 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T229 42943-42945 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T232 44230-44232 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T234 44240-44242 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T236 44780-44782 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T239 45216-45223 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T240 45259-45261 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T241 45316-45324 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T242 45362-45369 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T243 45605-45612 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T244 45989-45991 Chemical denotes DQ http://purl.obolibrary.org/obo/CHEBI_73827
T245 46000-46002 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T246 46008-46010 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T247 46011-46020 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T248 46230-46238 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T249 46807-46815 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T250 47075-47077 Chemical denotes NE http://purl.obolibrary.org/obo/CHEBI_73824
T251 47213-47216 Chemical denotes LPS http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_52603|http://purl.obolibrary.org/obo/CHEBI_89981
T254 47273-47280 Chemical denotes histone http://purl.obolibrary.org/obo/CHEBI_15358
T255 47300-47309 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T256 47311-47342 Chemical denotes suberoylanilide hydroxamic acid http://purl.obolibrary.org/obo/CHEBI_45716
T257 47327-47342 Chemical denotes hydroxamic acid http://purl.obolibrary.org/obo/CHEBI_24650
T258 47338-47342 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T259 47344-47348 Chemical denotes SAHA http://purl.obolibrary.org/obo/CHEBI_45716
T260 47611-47633 Chemical denotes guanosine triphosphate http://purl.obolibrary.org/obo/CHEBI_15996
T261 47611-47620 Chemical denotes guanosine http://purl.obolibrary.org/obo/CHEBI_16750
T262 47621-47633 Chemical denotes triphosphate http://purl.obolibrary.org/obo/CHEBI_18036
T263 47635-47638 Chemical denotes GTP http://purl.obolibrary.org/obo/CHEBI_15996|http://purl.obolibrary.org/obo/CHEBI_37565
T265 47648-47655 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T266 47894-47896 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T269 48113-48115 Chemical denotes PM http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551
T43074 49695-49697 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T8893 49787-49789 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T58026 49846-49848 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T21089 49878-49895 Chemical denotes autophagy inducer http://purl.obolibrary.org/obo/CHEBI_138880
T13491 49896-49903 Chemical denotes fisetin http://purl.obolibrary.org/obo/CHEBI_42567
T13283 50044-50046 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T81041 50193-50200 Chemical denotes fisetin http://purl.obolibrary.org/obo/CHEBI_42567
T67493 50764-50781 Chemical denotes autophagy inducer http://purl.obolibrary.org/obo/CHEBI_138880
T41027 50782-50791 Chemical denotes rapamycin http://purl.obolibrary.org/obo/CHEBI_9168
T7474 52102-52110 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T10275 52234-52242 Chemical denotes Ceramide http://purl.obolibrary.org/obo/CHEBI_17761
T30736 52388-52390 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T20364 52429-52431 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T64376 52433-52441 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T29910 52647-52650 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T71035 52834-52842 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T14738 52986-52994 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T16243 53636-53638 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T23 53910-53913 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T70674 53914-53917 Chemical denotes RNS http://purl.obolibrary.org/obo/CHEBI_33697|http://purl.obolibrary.org/obo/CHEBI_62764
T1713 54418-54420 Chemical denotes EB http://purl.obolibrary.org/obo/CHEBI_53197
T67128 54579-54581 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T28 54623-54631 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T29 54696-54703 Chemical denotes nucleus http://purl.obolibrary.org/obo/CHEBI_33252
T82215 55164-55166 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T31 55365-55367 Chemical denotes WT http://purl.obolibrary.org/obo/CHEBI_141450
T32 55382-55384 Chemical denotes PM http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551
T35 55579-55581 Chemical denotes WT http://purl.obolibrary.org/obo/CHEBI_141450
T36 55620-55623 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T15409 55695-55703 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T39 55949-55951 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T23076 56181-56183 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T76840 56192-56195 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T52316 56504-56506 Chemical denotes PM http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551
T37185 56527-56529 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T75089 56734-56742 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T4881 56845-56847 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T36562 56881-56889 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T51 56998-57003 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T52 57029-57031 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T85135 57123-57131 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T55 57135-57151 Chemical denotes lactosylceramide http://purl.obolibrary.org/obo/CHEBI_134507
T56 57243-57245 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T23892 57272-57280 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T59 57560-57562 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T29907 57662-57670 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T29761 57770-57778 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T18081 57821-57829 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T20617 58091-58094 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T47039 58119-58123 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T51156 58178-58186 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T36635 58225-58235 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T90157 58278-58286 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T73 59747-59749 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T91727 59801-59803 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T38305 59937-59947 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T134 60143-60145 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T56457 60304-60314 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T80 60364-60375 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T73677 60391-60400 Chemical denotes mucolytic http://purl.obolibrary.org/obo/CHEBI_77034
T72726 60469-60471 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T49800 60658-60667 Chemical denotes dendrimer http://purl.obolibrary.org/obo/CHEBI_51338|http://purl.obolibrary.org/obo/CHEBI_61483
T62899 60825-60834 Chemical denotes dendrimer http://purl.obolibrary.org/obo/CHEBI_51338|http://purl.obolibrary.org/obo/CHEBI_61483
T47656 60841-60846 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T15350 61032-61042 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T54058 61055-61064 Chemical denotes dendrimer http://purl.obolibrary.org/obo/CHEBI_51338|http://purl.obolibrary.org/obo/CHEBI_61483
T77653 61342-61346 Chemical denotes GSNO http://purl.obolibrary.org/obo/CHEBI_50091
T90481 61374-61392 Chemical denotes nitric oxide donor http://purl.obolibrary.org/obo/CHEBI_50566
T28575 61374-61386 Chemical denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480
T41830 61381-61386 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T97 61387-61392 Chemical denotes donor http://purl.obolibrary.org/obo/CHEBI_17891
T18880 61436-61438 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T99 61569-61573 Chemical denotes GSNO http://purl.obolibrary.org/obo/CHEBI_50091
T100 61622-61625 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T38467 61723-61725 Chemical denotes PM http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551
T23686 61823-61825 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T105 61830-61832 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T44313 62099-62103 Chemical denotes GSNO http://purl.obolibrary.org/obo/CHEBI_50091
T97111 62174-62178 Chemical denotes GSNO http://purl.obolibrary.org/obo/CHEBI_50091
T108 62251-62253 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T109 62297-62307 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T111 62312-62316 Chemical denotes GSNO http://purl.obolibrary.org/obo/CHEBI_50091
T112 62388-62393 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T54131 62403-62414 Chemical denotes gemfibrozil http://purl.obolibrary.org/obo/CHEBI_5296
T17954 62416-62419 Chemical denotes GEM http://purl.obolibrary.org/obo/CHEBI_5296
T48946 62460-62467 Chemical denotes fisetin http://purl.obolibrary.org/obo/CHEBI_42567
T116 62484-62486 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T117 62572-62574 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T16262 62706-62709 Chemical denotes GEM http://purl.obolibrary.org/obo/CHEBI_5296
T83227 62710-62717 Chemical denotes fisetin http://purl.obolibrary.org/obo/CHEBI_42567
T14089 62980-62991 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T9718 62992-62999 Chemical denotes fisetin http://purl.obolibrary.org/obo/CHEBI_42567
T93835 63024-63026 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T87765 63275-63280 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T5256 63460-63469 Chemical denotes rapamycin http://purl.obolibrary.org/obo/CHEBI_9168
T13696 63697-63704 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T67833 63837-63839 Chemical denotes PM http://purl.obolibrary.org/obo/CHEBI_141444|http://purl.obolibrary.org/obo/CHEBI_16410|http://purl.obolibrary.org/obo/CHEBI_53551
T129 64181-64191 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T27730 64202-64213 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T79502 64214-64218 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T133 64539-64549 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T17243 64714-64724 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T137 64745-64747 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T8987 64795-64803 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T140 64978-64986 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T96107 65487-65489 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T144 65509-65518 Chemical denotes bleomycin http://purl.obolibrary.org/obo/CHEBI_22907
T70425 66819-66827 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T55907 67027-67031 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T147 67169-67179 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T9752 67181-67191 Chemical denotes Cysteamine http://purl.obolibrary.org/obo/CHEBI_17141
T150 67211-67215 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T60258 67276-67287 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T152 67328-67337 Chemical denotes mucolytic http://purl.obolibrary.org/obo/CHEBI_77034
T153 67426-67436 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T58412 68049-68053 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T85472 68161-68171 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T158 68258-68268 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T55491 68361-68368 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T7519 68491-68501 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T44863 68751-68761 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T28868 68885-68894 Chemical denotes dendrimer http://purl.obolibrary.org/obo/CHEBI_51338|http://purl.obolibrary.org/obo/CHEBI_61483
T31667 69246-69257 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T19153 69286-69289 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T4318 69515-69524 Chemical denotes rapamycin http://purl.obolibrary.org/obo/CHEBI_9168
T84057 69665-69672 Chemical denotes fisetin http://purl.obolibrary.org/obo/CHEBI_42567
T42004 69703-69714 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T15814 70360-70371 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T63851 70515-70517 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T174 70519-70530 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T66577 70714-70716 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T99338 70717-70728 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T70909 70811-70822 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T83059 70916-70919 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T72009 71115-71118 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T3847 71159-71162 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T45661 71178-71189 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T7261 71245-71256 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T16389 71401-71404 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T41546 71480-71490 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T46239 71541-71544 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T36363 71761-71771 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T73018 71867-71877 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T1111 72017-72027 Chemical denotes cysteamine http://purl.obolibrary.org/obo/CHEBI_17141|http://purl.obolibrary.org/obo/CHEBI_58029
T1375 72073-72076 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T41711 72226-72243 Chemical denotes autophagy inducer http://purl.obolibrary.org/obo/CHEBI_138880
T79487 72294-72296 Chemical denotes AR http://purl.obolibrary.org/obo/CHEBI_137238
T42919 72351-72353 Chemical denotes AR http://purl.obolibrary.org/obo/CHEBI_137238
T65482 72426-72437 Chemical denotes methicillin http://purl.obolibrary.org/obo/CHEBI_6827
T79994 72572-72574 Chemical denotes AR http://purl.obolibrary.org/obo/CHEBI_137238
T70610 72598-72609 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T48393 72902-72905 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T91062 72971-72976 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T29551 73221-73226 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T35255 73304-73307 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T204 73410-73421 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T11966 73474-73477 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T206 73807-73817 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T99783 73956-73965 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T208 74314-74323 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T57643 74426-74436 Chemical denotes budesonide http://purl.obolibrary.org/obo/CHEBI_3207
T86220 74440-74454 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T39526 74679-74689 Chemical denotes budesonide http://purl.obolibrary.org/obo/CHEBI_3207
T39935 74788-74797 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T213 74808-74818 Chemical denotes budesonide http://purl.obolibrary.org/obo/CHEBI_3207
T91389 74879-74890 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T99571 74895-74909 Chemical denotes bafilomycin A1 http://purl.obolibrary.org/obo/CHEBI_22689
T87751 74941-74950 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T15725 74961-74971 Chemical denotes budesonide http://purl.obolibrary.org/obo/CHEBI_3207
T83295 75013-75026 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T78343 75036-75050 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T7124 75266-75271 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T221 76063-76073 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T75469 76094-76105 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T223 76675-76680 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T224 76899-76909 Chemical denotes spermidine http://purl.obolibrary.org/obo/CHEBI_16610|http://purl.obolibrary.org/obo/CHEBI_57834
T226 76914-76931 Chemical denotes autophagy inducer http://purl.obolibrary.org/obo/CHEBI_138880
T28856 76934-76941 Chemical denotes MK-2206 http://purl.obolibrary.org/obo/CHEBI_67271
T55676 76934-76936 Chemical denotes MK http://purl.obolibrary.org/obo/CHEBI_74706
T27210 76950-76959 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T230 76990-77000 Chemical denotes stabilizer http://purl.obolibrary.org/obo/CHEBI_77966
T231 77098-77107 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T63795 77260-77265 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T233 77410-77420 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T89564 77593-77603 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T235 77783-77788 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T11038 78056-78061 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T237 78115-78118 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T238 78168-78178 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T75877 78248-78251 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T20047 78401-78406 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T57792 78626-78635 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T52731 78744-78747 Chemical denotes MDR http://purl.obolibrary.org/obo/CHEBI_53218
T40974 78840-78851 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T81365 78856-78866 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T4284 78989-78994 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T90594 79281-79283 Chemical denotes NV http://purl.obolibrary.org/obo/CHEBI_73825
T32793 79487-79489 Chemical denotes NV http://purl.obolibrary.org/obo/CHEBI_73825
T6664 79854-79856 Chemical denotes NV http://purl.obolibrary.org/obo/CHEBI_73825
T36631 79940-79947 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T14237 79987-79989 Chemical denotes NV http://purl.obolibrary.org/obo/CHEBI_73825
T21034 80040-80044 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T252 80111-80113 Chemical denotes NV http://purl.obolibrary.org/obo/CHEBI_73825
T253 80534-80539 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T10396 80807-80830 Chemical denotes reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_26523
T73114 80816-80822 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T39296 80832-80835 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T23627 80975-80978 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T70793 81045-81053 Chemical denotes ceramide http://purl.obolibrary.org/obo/CHEBI_17761|http://purl.obolibrary.org/obo/CHEBI_52639
T95168 81460-81463 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T27764 82385-82393 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T33920 82575-82586 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T60874 82637-82646 Chemical denotes mucolytic http://purl.obolibrary.org/obo/CHEBI_77034

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id tao:has_standard_notation
2 77-88 Species denotes Respiratory Tax:12814
3 93-101 Disease denotes COVID-19 MESH:C000657245
26 1498-1549 Gene denotes cystic fibrosis transmembrane conductance regulator Gene:1080
27 1551-1555 Gene denotes CFTR Gene:1080
28 513-524 Species denotes respiratory Tax:12814
29 1342-1353 Species denotes respiratory Tax:12814
30 571-584 Disease denotes lung diseases MESH:D008171
31 594-631 Disease denotes chronic obstructive pulmonary disease MESH:D029424
32 633-637 Disease denotes COPD MESH:D029424
33 640-655 Disease denotes cystic fibrosis MESH:D003550
34 662-691 Disease denotes idiopathic pulmonary fibrosis MESH:D054990
35 699-716 Disease denotes acute lung injury MESH:D055371
36 724-759 Disease denotes acute respiratory distress syndrome MESH:D012128
37 761-765 Disease denotes ARDS MESH:D012128
38 772-796 Disease denotes coronavirus disease-2019 MESH:C000657245
39 798-806 Disease denotes COVID-19 MESH:C000657245
40 1152-1164 Disease denotes lung disease MESH:D008171
41 1265-1280 Disease denotes viral infection MESH:D001102
42 1434-1447 Disease denotes lung diseases MESH:D008171
43 1608-1620 Disease denotes lung disease MESH:D008171
44 1789-1802 Disease denotes lung diseases MESH:D008171
45 1852-1856 Disease denotes COPD MESH:D029424
46 1866-1870 Disease denotes ARDS MESH:D012128
47 1875-1883 Disease denotes COVID-19 MESH:C000657245
61 2042-2053 Species denotes respiratory Tax:12814
62 2946-2957 Species denotes respiratory Tax:12814
63 1938-1951 Disease denotes lung diseases MESH:D008171
64 1984-1993 Disease denotes mortality MESH:D003643
65 2185-2190 Disease denotes death MESH:D003643
66 2975-3012 Disease denotes chronic obstructive pulmonary disease MESH:D029424
67 3014-3018 Disease denotes COPD MESH:D029424
68 3021-3036 Disease denotes cystic fibrosis MESH:D003550
69 3043-3060 Disease denotes acute lung injury MESH:D055371
70 3068-3103 Disease denotes acute respiratory distress syndrome MESH:D012128
71 3105-3109 Disease denotes ARDS MESH:D012128
72 3116-3140 Disease denotes coronavirus disease-2019 MESH:C000657245
73 3142-3150 Disease denotes COVID-19 MESH:C000657245
89 4957-5008 Gene denotes cystic fibrosis transmembrane conductance regulator Gene:1080
90 5010-5014 Gene denotes CFTR Gene:1080
91 5329-5331 Gene denotes PN Gene:79650
92 4477-4479 Gene denotes PN Gene:79650
93 3909-3911 Gene denotes PN Gene:79650
94 3714-3716 Gene denotes PN Gene:79650
95 4351-4357 Chemical denotes lipids MESH:D008055
96 4663-4669 Chemical denotes lipids MESH:D008055
97 3381-3390 Disease denotes infection MESH:D007239
98 4571-4584 Disease denotes dysfunctional MESH:D009461
99 5030-5043 Disease denotes dysfunctional MESH:D009461
100 5399-5414 Disease denotes proteinopathies MESH:C563476
101 5416-5442 Disease denotes neurodegenerative diseases MESH:D019636
102 5479-5499 Disease denotes respiratory diseases MESH:D012140
103 5515-5519 Disease denotes COPD MESH:D029424
114 6296-6311 Gene denotes cigarette smoke Gene:1431
115 6313-6315 Gene denotes CS Gene:1431
116 5627-5634 Species denotes tobacco Tax:4097
117 5837-5844 Species denotes tobacco Tax:4097
118 5541-5563 Disease denotes Respiratory infections MESH:D012141
119 5689-5703 Disease denotes COPD-emphysema MESH:D029424
120 6006-6020 Disease denotes COPD-emphysema MESH:D029424
121 6227-6249 Disease denotes respiratory infections MESH:D012141
122 6325-6375 Disease denotes phagocytosis defects involves autophagy impairment MESH:D006331
123 6489-6499 Disease denotes infections MESH:D007239
131 6907-6909 Gene denotes PN Gene:79650
132 6594-6596 Gene denotes CS Gene:1431
133 6729-6739 Disease denotes infections MESH:D007239
134 6751-6763 Disease denotes lung disease MESH:D008171
135 6841-6861 Disease denotes pulmonary infections MESH:D012141
136 7039-7054 Disease denotes lung infections MESH:D012141
137 7287-7301 Disease denotes COPD-emphysema MESH:D029424
142 7501-7523 Species denotes Pseudomonas aeruginosa Tax:287
143 7525-7538 Species denotes P. aeruginosa Tax:287
144 7586-7599 Species denotes P. aeruginosa Tax:287
145 7615-7621 Species denotes murine Tax:10090
171 7653-7672 Gene denotes autophagy-related 7 Gene:74244
172 7674-7678 Gene denotes ATG7 Gene:74244
173 8203-8222 Gene denotes interleukin (IL)-17 Gene:16171
174 8355-8360 Gene denotes IL-22 Gene:50616
175 7742-7748 Species denotes murine Tax:10090
176 7768-7789 Species denotes Klebsiella pneumoniae Tax:573
177 7882-7902 Species denotes Chlamydia pneumoniae Tax:83558
178 7906-7910 Species denotes mice Tax:10090
179 7963-7967 Species denotes mice Tax:10090
180 8250-8254 Species denotes mice Tax:10090
181 8269-8296 Species denotes respiratory syncytial virus Tax:12814
182 8484-8535 Species denotes Middle East respiratory syndrome (MERS) coronavirus Tax:1335626
183 8652-8661 Species denotes SARS-COV2 Tax:2697049
184 7804-7815 Species denotes respiratory Tax:12814
185 8298-8301 Species denotes RSV Tax:12814
186 8370-8373 Species denotes RSV Tax:12814
187 7857-7876 Disease denotes pulmonary infection MESH:D012141
188 8016-8025 Disease denotes mortality MESH:D003643
189 8096-8112 Disease denotes viral infections MESH:D001102
190 8173-8193 Disease denotes autophagy deficiency MESH:C564093
191 8255-8263 Disease denotes infected MESH:D007239
192 8662-8671 Disease denotes infection MESH:D007239
193 8716-8720 Disease denotes ARDS MESH:D012128
194 8726-8734 Disease denotes COVID-19 MESH:C000657245
195 8741-8753 Disease denotes lung disease MESH:D008171
217 8958-8962 Gene denotes CFTR Gene:1080
218 9039-9043 Gene denotes CFTR Gene:1080
219 9081-9085 Gene denotes CFTR Gene:1080
220 9370-9374 Gene denotes CFTR Gene:12638
221 9540-9544 Gene denotes NFκB Gene:18033
222 9624-9628 Gene denotes CFTR Gene:12638
223 9637-9660 Gene denotes tumor necrosis factor α Gene:7124
224 9662-9666 Gene denotes TNFα Gene:7124
225 9677-9681 Gene denotes NFκB Gene:18033
226 9735-9739 Gene denotes CFTR Gene:12638
227 9823-9827 Gene denotes NFκB Gene:18033
228 9947-9951 Gene denotes CFTR Gene:12638
229 9337-9341 Species denotes mice Tax:10090
230 9791-9795 Species denotes mice Tax:10090
231 8848-8860 Disease denotes inflammation MESH:D007249
232 8866-8875 Disease denotes infection MESH:D007239
233 8922-8938 Disease denotes genetic disorder MESH:D030342
234 9196-9206 Disease denotes infections MESH:D007239
235 9219-9231 Disease denotes inflammation MESH:D007249
236 9764-9784 Disease denotes aeruginosa infection MESH:D011552
237 9890-9902 Disease denotes lung disease MESH:D008171
248 10409-10413 Gene denotes CFTR Gene:1080
249 10489-10492 Gene denotes CD4 Gene:920
250 10503-10506 Gene denotes CD4 Gene:920
251 10507-10512 Gene denotes FoxP3 Gene:50943
252 10646-10710 Gene denotes transient receptor potential cation channel subfamily C member 6 Gene:7225
253 10712-10717 Gene denotes TRPC6 Gene:7225
254 10147-10165 Disease denotes dysfunctional CFTR MESH:D009461
255 10255-10265 Disease denotes infections MESH:D007239
256 10598-10614 Disease denotes CFTR dysfunction MESH:D009461
257 10790-10810 Disease denotes CF-lung inflammation MESH:D011014
274 10981-10985 Gene denotes CFTR Gene:1080
275 11127-11145 Gene denotes transglutaminase-2 Gene:7052
276 11147-11152 Gene denotes TGM-2 Gene:7052
277 11179-11187 Gene denotes Beclin-1 Gene:8678
278 11286-11290 Gene denotes CFTR Gene:1080
279 11304-11306 Gene denotes CS Gene:1431
280 11331-11335 Gene denotes CFTR Gene:1080
281 11074-11097 Chemical denotes reactive oxygen species MESH:D017382
282 11099-11102 Chemical denotes ROS MESH:D017382
283 11438-11441 Chemical denotes ROS MESH:D017382
284 10897-10912 Disease denotes lung infections MESH:D012141
285 11034-11058 Disease denotes CFTR loss or dysfunction MESH:D006474
286 11255-11282 Disease denotes genetic loss or dysfunction MESH:D030342
287 11418-11422 Disease denotes COPD MESH:D029424
288 11492-11508 Disease denotes CFTR dysfunction MESH:D009461
289 11667-11671 Disease denotes COPD MESH:D029424
301 12062-12073 Species denotes respiratory Tax:12814
302 12339-12350 Species denotes respiratory Tax:12814
303 11785-11801 Disease denotes CFTR dysfunction MESH:D009461
304 11833-11837 Disease denotes COPD MESH:D029424
305 11872-11896 Disease denotes opportunistic infections MESH:D009894
306 12095-12099 Disease denotes COPD MESH:D029424
307 12105-12109 Disease denotes ARDS MESH:D012128
308 12114-12122 Disease denotes COVID-19 MESH:C000657245
309 12178-12198 Disease denotes pulmonary infections MESH:D012141
310 12203-12221 Disease denotes immune dysfunction MESH:D007154
311 12309-12321 Disease denotes lung disease MESH:D008171
313 12394-12415 Disease denotes Respiratory Infection MESH:D012141
319 13002-13013 Species denotes respiratory Tax:12814
320 12564-12570 Chemical denotes lipids MESH:D008055
321 12529-12542 Disease denotes dysfunctional MESH:D009461
322 12629-12642 Disease denotes dysfunctional MESH:D009461
323 12823-12833 Disease denotes infections MESH:D007239
333 13424-13450 Species denotes Mycobacterium tuberculosis Tax:1773
334 13452-13467 Species denotes M. tuberculosis Tax:1773
335 13524-13539 Species denotes M. tuberculosis Tax:1773
336 13795-13810 Species denotes M. tuberculosis Tax:1773
337 13956-13971 Species denotes M. tuberculosis Tax:1773
338 13814-13825 Species denotes respiratory Tax:12814
339 13335-13367 Disease denotes respiratory bacterial infections MESH:D012141
340 13510-13522 Disease denotes tuberculosis MESH:D014376
341 13585-13595 Disease denotes granulomas MESH:D006099
356 13998-14022 Species denotes Streptococcus pneumoniae Tax:1313
357 14024-14037 Species denotes S. pneumoniae Tax:1313
358 14321-14334 Species denotes S. pneumoniae Tax:1313
359 14591-14613 Species denotes Pseudomonas aeruginosa Tax:287
360 14615-14628 Species denotes P. aeruginosa Tax:287
361 14641-14662 Species denotes Klebsiella pneumoniae Tax:573
362 14800-14818 Chemical denotes lipopolysaccharide MESH:D008070
363 14101-14110 Disease denotes pneumonia MESH:D011014
364 14148-14157 Disease denotes infection MESH:D007239
365 14335-14344 Disease denotes infection MESH:D007239
366 14497-14506 Disease denotes pneumonia MESH:D011014
367 14927-14939 Disease denotes inflammation MESH:D007249
368 14954-14965 Disease denotes lung injury MESH:D055370
369 15054-15065 Disease denotes lung injury MESH:D055370
377 15320-15335 Species denotes influenza virus Tax:11308
378 15650-15659 Species denotes SARS-CoV2 Tax:2697049
379 15164-15175 Species denotes respiratory Tax:12814
380 15594-15605 Species denotes respiratory Tax:12814
381 15800-15811 Species denotes respiratory Tax:12814
382 15622-15625 Species denotes RSV Tax:12814
383 15142-15152 Disease denotes infections MESH:D007239
403 16222-16245 Gene denotes transcription factor-EB Gene:7942
404 16247-16251 Gene denotes TFEB Gene:7942
405 16339-16343 Gene denotes TFEB Gene:7942
406 16403-16407 Gene denotes TFEB Gene:7942
407 16497-16501 Gene denotes TFEB Gene:7942
408 16660-16663 Gene denotes p62 Gene:51164
409 17315-17317 Gene denotes CS Gene:1431
410 16786-16788 Gene denotes CS Gene:1431
411 16096-16111 Gene denotes cigarette smoke Gene:1431
412 17209-17211 Gene denotes CS Gene:1431
413 16591-16593 Gene denotes CS Gene:1431
414 16462-16464 Gene denotes CS Gene:1431
415 16359-16361 Gene denotes CS Gene:1431
416 16179-16181 Gene denotes CS Gene:1431
417 16113-16115 Gene denotes CS Gene:1431
418 15952-15965 Disease denotes dysfunctional MESH:D009461
419 16311-16324 Disease denotes dysfunctional MESH:D009461
420 16998-17019 Disease denotes pulmonary dysfunction MESH:D011660
421 17416-17426 Disease denotes infections MESH:D007239
431 18182-18186 Gene denotes PLP2 Gene:5355
432 18307-18311 Gene denotes NSP6 Gene:43740578
433 17697-17712 Species denotes influenza virus Tax:11308
434 18041-18086 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
435 18088-18096 Species denotes SARS-CoV Tax:694009
436 18316-18329 Species denotes coronaviruses Tax:11118
437 18424-18435 Species denotes coronavirus Tax:11118
438 17859-17868 Species denotes Influenza Tax:11320
439 17809-17846 Disease denotes impairment via aggresome accumulation MESH:D060825
449 19088-19103 Species denotes M. tuberculosis Tax:1773
450 19218-19233 Species denotes M. tuberculosis Tax:1773
451 19413-19419 Species denotes humans Tax:9606
452 18541-18564 Disease denotes Legionella pneumophilia MESH:D007877
453 18569-18581 Disease denotes pneumophilia
454 18626-18634 Disease denotes infected MESH:D007239
455 18786-18798 Disease denotes pneumophilia
456 18878-18887 Disease denotes infection MESH:D007239
457 18964-18976 Disease denotes pneumophilia
467 19494-19498 Gene denotes CFTR Gene:1080
468 19584-19588 Gene denotes CFTR Gene:1080
469 19706-19710 Gene denotes CFTR Gene:1080
470 19763-19767 Gene denotes CFTR Gene:1080
471 19908-19912 Gene denotes CFTR Gene:1080
472 20083-20087 Gene denotes CFTR Gene:1080
473 19688-19696 Species denotes patients Tax:9606
474 19995-20003 Species denotes patients Tax:9606
475 20069-20082 Disease denotes dysfunctional MESH:D009461
491 20193-20197 Gene denotes CFTR Gene:1080
492 20560-20564 Gene denotes CFTR Gene:1080
493 20334-20336 Gene denotes CS Gene:1431
494 20663-20665 Gene denotes CS Gene:1431
495 20513-20515 Gene denotes CS Gene:1431
496 20242-20244 Gene denotes CS Gene:1431
497 20491-20499 Species denotes patients Tax:9606
498 20413-20421 Chemical denotes ceramide MESH:D002518
499 20543-20546 Chemical denotes ROS MESH:D017382
500 20135-20151 Disease denotes CFTR dysfunction MESH:D009461
501 20299-20315 Disease denotes CFTR dysfunction MESH:D009461
502 20345-20361 Disease denotes CFTR dysfunction MESH:D009461
503 20450-20482 Disease denotes altered sphingolipid homeostasis MESH:D013106
504 20486-20490 Disease denotes COPD MESH:D029424
505 20724-20740 Disease denotes CFTR dysfunction MESH:D009461
507 20821-20841 Disease denotes Respiratory Diseases MESH:D012140
520 21190-21192 Gene denotes CS Gene:1431
521 21253-21255 Gene denotes CS Gene:1431
522 21179-21182 Chemical denotes ROS MESH:D017382
523 21244-21247 Chemical denotes ROS MESH:D017382
524 21323-21326 Chemical denotes ROS MESH:D017382
525 21741-21744 Chemical denotes ROS MESH:D017382
526 21030-21040 Disease denotes infections MESH:D007239
527 21123-21143 Disease denotes respiratory diseases MESH:D012140
528 21450-21470 Disease denotes lung cellular injury MESH:D055370
529 21546-21559 Disease denotes lung diseases MESH:D008171
530 21569-21583 Disease denotes COPD-emphysema MESH:D029424
531 21602-21631 Disease denotes idiopathic pulmonary fibrosis MESH:D054990
533 21964-21981 Disease denotes Acute Lung Injury MESH:D055371
571 22822-22827 Gene denotes IL-1β Gene:16175
572 22832-22836 Gene denotes TNFα Gene:21926
573 23015-23044 Gene denotes mammalian target of rapamycin Gene:2475
574 23046-23050 Gene denotes mTOR Gene:2475
575 23185-23189 Gene denotes NFκB Gene:4790
576 23533-23569 Gene denotes proteins interacting with C-kinase 1 Gene:18693
577 23571-23576 Gene denotes PICK1 Gene:18693
578 23686-23689 Gene denotes CLP Gene:12950
579 24211-24215 Gene denotes mTOR Gene:2475
580 24488-24492 Gene denotes Atg7 Gene:74244
581 24494-24498 Gene denotes Atg5 Gene:11793
582 24503-24508 Gene denotes Atg4a Gene:666468
583 22702-22706 Species denotes mice Tax:10090
584 23581-23585 Species denotes mice Tax:10090
585 23762-23768 Species denotes murine Tax:10090
586 23974-23979 Species denotes human Tax:9606
587 24435-24439 Species denotes mice Tax:10090
588 24197-24206 Chemical denotes rapamycin MESH:D020123
589 22052-22069 Disease denotes acute lung injury MESH:D055371
590 22447-22467 Disease denotes bacterial infections MESH:D001424
591 22469-22478 Disease denotes hyperoxia MESH:D018496
592 22480-22486 Disease denotes sepsis MESH:D018805
593 22599-22616 Disease denotes acute lung injury MESH:D055371
594 22621-22633 Disease denotes inflammation MESH:D007249
595 22687-22698 Disease denotes lung injury MESH:D055370
596 22725-22735 Disease denotes lung edema MESH:D004487
597 22771-22782 Disease denotes hemorrhages MESH:D006470
598 23137-23148 Disease denotes lung injury MESH:D055370
599 23348-23367 Disease denotes acute lung injuries MESH:D055371
600 23486-23492 Disease denotes sepsis MESH:D018805
601 23501-23512 Disease denotes lung injury MESH:D055370
602 23638-23649 Disease denotes lung injury MESH:D055370
603 23700-23706 Disease denotes sepsis MESH:D018805
604 23779-23788 Disease denotes hyperoxia MESH:D018496
605 23830-23856 Disease denotes bronchopulmonary dysplasia MESH:D001997
606 24142-24153 Disease denotes lung injury MESH:D055370
607 24350-24361 Disease denotes lung injury MESH:D055370
610 24648-24683 Disease denotes Acute Respiratory Distress Syndrome MESH:D012128
611 24685-24689 Disease denotes ARDS MESH:D012128
643 25031-25034 Gene denotes CLP Gene:12950
644 25224-25239 Gene denotes myeloperoxidase Gene:17523
645 25241-25244 Gene denotes MPO Gene:17523
646 25384-25403 Gene denotes lipoxin A4 receptor Gene:681706
647 25638-25643 Gene denotes MAPK1 Gene:5594
648 25648-25653 Gene denotes MAPK8 Gene:5599
649 25687-25691 Gene denotes mTOR Gene:2475
650 26182-26187 Gene denotes IL-1β Gene:3552
651 26396-26401 Gene denotes IL-1β Gene:3552
652 25005-25011 Species denotes murine Tax:10090
653 25476-25480 Species denotes rats Tax:10116
654 25815-25818 Species denotes rat Tax:10116
655 26868-26876 Species denotes patients Tax:9606
656 25092-25101 Chemical denotes rapamycin MESH:D020123
657 24732-24767 Disease denotes acute respiratory distress syndrome MESH:D012128
658 24772-24776 Disease denotes ARDS MESH:D012128
659 24856-24860 Disease denotes ARDS MESH:D012128
660 24899-24903 Disease denotes ARDS MESH:D012128
661 24968-24973 Disease denotes death MESH:D003643
662 25307-25313 Disease denotes sepsis MESH:D018805
663 25326-25330 Disease denotes ARDS MESH:D012128
664 25457-25472 Disease denotes septic ALI/ARDS MESH:D012128
665 25873-25877 Disease denotes ARDS MESH:D012128
666 25921-25932 Disease denotes lung injury MESH:D055370
667 25959-25963 Disease denotes ARDS MESH:D012128
668 26156-26160 Disease denotes ARDS MESH:D012128
669 26450-26459 Disease denotes hypoxemia MESH:D000860
670 26515-26519 Disease denotes ARDS MESH:D012128
671 26600-26604 Disease denotes ARDS MESH:D012128
672 26725-26729 Disease denotes ARDS MESH:D012128
673 26860-26864 Disease denotes ARDS MESH:D012128
675 26914-26922 Disease denotes COVID-19 MESH:C000657245
697 27781-27785 Gene denotes NSP6 Gene:43740578
698 28077-28081 Gene denotes PLP2 Gene:5355
699 26949-26959 Species denotes SARS-CoV-2 Tax:2697049
700 27223-27233 Species denotes SARS-CoV-2 Tax:2697049
701 27277-27287 Species denotes SARS-CoV-2 Tax:2697049
702 27542-27552 Species denotes SARS-CoV-2 Tax:2697049
703 27735-27745 Species denotes SARS-CoV-2 Tax:2697049
704 28103-28111 Species denotes SARS-CoV Tax:694009
705 28116-28124 Species denotes MERS-CoV Tax:1335626
706 28272-28282 Species denotes SARS-CoV-2 Tax:2697049
707 28340-28350 Species denotes SARS-CoV-2 Tax:2697049
708 28490-28503 Species denotes coronaviruses Tax:11118
709 27244-27260 Disease denotes viral infections MESH:D001102
710 27308-27316 Disease denotes COVID-19 MESH:C000657245
711 27379-27388 Disease denotes pneumonia MESH:D011014
712 27400-27411 Disease denotes lung damage MESH:D008171
713 27453-27475 Disease denotes ARDS-like lung disease MESH:D012128
714 27495-27504 Disease denotes mortality MESH:D003643
715 27632-27640 Disease denotes COVID-19 MESH:C000657245
716 27641-27653 Disease denotes lung disease MESH:D008171
717 27690-27708 Disease denotes immune dysfunction MESH:D007154
741 29019-29029 Species denotes SARS-CoV-2 Tax:2697049
742 29308-29317 Species denotes SARS-COV2 Tax:2697049
743 30015-30066 Species denotes Middle East respiratory syndrome (MERS) coronavirus Tax:1335626
744 30167-30176 Species denotes SARS-COV2 Tax:2697049
745 28966-28976 Chemical denotes spermidine MESH:D013095
746 28978-28985 Chemical denotes MK02206
747 28991-29002 Chemical denotes niclosamide MESH:D009534
748 29548-29566 Chemical denotes hydroxychloroquine MESH:D006886
749 29568-29571 Chemical denotes HCQ MESH:D006886
750 29786-29789 Chemical denotes HCQ MESH:D006886
751 28654-28670 Disease denotes viral infections MESH:D001102
752 29223-29231 Disease denotes COVID-19 MESH:C000657245
753 29401-29409 Disease denotes COVID-19 MESH:C000657245
754 29613-29633 Disease denotes rheumatoid arthritis MESH:D001172
755 29635-29642 Disease denotes malaria MESH:D008288
756 29822-29830 Disease denotes COVID-19 MESH:C000657245
757 29886-29894 Disease denotes COVID-19 MESH:C000657245
758 30177-30186 Disease denotes infection MESH:D007239
759 30235-30239 Disease denotes ARDS MESH:D012128
760 30245-30253 Disease denotes COVID-19 MESH:C000657245
761 30260-30272 Disease denotes lung disease MESH:D008171
762 30356-30360 Disease denotes ARDS MESH:D012128
763 30431-30452 Disease denotes SARS-CoV-2 infections MESH:C000657245
776 30699-30709 Species denotes SARS-CoV-2 Tax:2697049
777 30908-30918 Species denotes SARS-CoV-2 Tax:2697049
778 30634-30647 Disease denotes lung diseases MESH:D008171
779 30791-30799 Disease denotes COVID-19 MESH:C000657245
780 30935-30943 Disease denotes COVID-19 MESH:C000657245
781 31142-31146 Disease denotes ARDS MESH:D012128
782 31163-31171 Disease denotes COVID-19 MESH:C000657245
783 31269-31293 Disease denotes gastrointestinal systems MESH:D005767
784 31575-31592 Disease denotes lung inflammation MESH:D011014
785 31698-31707 Disease denotes infection MESH:D007239
786 31776-31784 Disease denotes COVID-19 MESH:C000657245
787 31815-31824 Disease denotes mortality MESH:D003643
789 31867-31871 Disease denotes COPD MESH:D029424
829 32530-32533 Gene denotes p62 Gene:51164
830 32612-32616 Gene denotes LC3B Gene:81631
831 33433-33437 Gene denotes TFEB Gene:7942
832 33755-33759 Gene denotes TFEB Gene:7942
833 33945-33949 Gene denotes TFEB Gene:7942
834 34109-34113 Gene denotes TFEB Gene:7942
835 34260-34264 Gene denotes TFEB Gene:7942
836 34477-34481 Gene denotes TFEB Gene:7942
837 34719-34730 Gene denotes bicaudal D1 Gene:636
838 34732-34737 Gene denotes BICD1 Gene:636
839 34886-34889 Gene denotes p62 Gene:51164
840 34995-35000 Gene denotes BICD1 Gene:12121
841 35079-35084 Gene denotes BICD1 Gene:12121
842 35090-35093 Gene denotes p62 Gene:67665
843 35119-35122 Gene denotes p62 Gene:67665
844 35174-35179 Gene denotes BICD1 Gene:12121
845 32134-32139 Species denotes human Tax:9606
846 32194-32199 Species denotes human Tax:9606
847 32788-32792 Species denotes mice Tax:10090
848 33337-33343 Species denotes murine Tax:10090
849 34840-34848 Species denotes patients Tax:9606
850 34967-34971 Species denotes mice Tax:10090
851 32032-32040 Chemical denotes nicotine MESH:D009538
852 34051-34066 Chemical denotes ethyl carbamate MESH:D014520
853 32050-32061 Disease denotes lung injury MESH:D055370
854 32066-32080 Disease denotes COPD-emphysema MESH:D029424
855 32218-32232 Disease denotes COPD-emphysema MESH:D029424
856 32851-32860 Disease denotes emphysema MESH:D004646
857 32937-32951 Disease denotes COPD-emphysema MESH:D029424
858 33019-33028 Disease denotes emphysema MESH:D004646
859 33213-33227 Disease denotes COPD-emphysema MESH:D029424
860 33354-33368 Disease denotes COPD-emphysema MESH:D029424
861 33498-33510 Disease denotes lung disease MESH:D008171
862 33553-33567 Disease denotes COPD-emphysema MESH:D029424
863 34025-34039 Disease denotes hepatotoxicity MESH:D056486
864 34178-34186 Disease denotes toxicity MESH:D064420
865 34435-34449 Disease denotes COPD-emphysema MESH:D029424
866 34657-34671 Disease denotes COPD-emphysema MESH:D029424
867 34835-34839 Disease denotes COPD MESH:D029424
884 35605-35609 Gene denotes Atg5 Gene:11793
885 35675-35709 Gene denotes secretoglobulin family 1A member 1 Gene:22287
886 35711-35718 Gene denotes SCGB1A1 Gene:22287
887 35744-35752 Gene denotes A1 and D Gene:21423
888 35754-35760 Gene denotes Sftpa1 Gene:20387
889 35765-35770 Gene denotes Sftpd Gene:20390
890 35844-35851 Gene denotes SCGB1A1 Gene:7356
891 36211-36213 Gene denotes CS Gene:1431
892 35970-35972 Gene denotes CS Gene:1431
893 35550-35552 Gene denotes CS Gene:1431
894 35569-35573 Species denotes Mice Tax:10090
895 35435-35444 Disease denotes infection MESH:D007239
896 35784-35797 Disease denotes abnormal club MESH:D010005
897 35943-35947 Disease denotes COPD MESH:D029424
898 36130-36134 Disease denotes COPD MESH:D029424
899 36374-36378 Disease denotes COPD MESH:D029424
901 36416-36431 Disease denotes Cystic Fibrosis MESH:D003550
923 36721-36725 Gene denotes CFTR Gene:1080
924 36880-36884 Gene denotes CFTR Gene:1080
925 36937-36945 Gene denotes Beclin-1 Gene:8678
926 37000-37004 Gene denotes CFTR Gene:1080
927 37010-37013 Gene denotes p62 Gene:51164
928 37014-37019 Gene denotes HDAC6 Gene:10013
929 37829-37834 Gene denotes Atg12 Gene:9140
930 36898-36901 Gene denotes TG2 Gene:21817
931 37424-37432 Species denotes patients Tax:9606
932 37481-37494 Species denotes P. aeruginosa Tax:287
933 37499-37523 Species denotes Burkholderia cenocepacia Tax:95486
934 37525-37539 Species denotes B. cenocepacia Tax:95486
935 36787-36790 Chemical denotes ROS MESH:D017382
936 36894-36897 Chemical denotes ROS MESH:D017382
937 36432-36447 Disease denotes Cystic fibrosis MESH:D003550
938 36453-36485 Disease denotes chronic obstructive lung disease MESH:D029424
939 36515-36525 Disease denotes infections MESH:D007239
940 36618-36636 Disease denotes airway obstruction MESH:D000402
941 36764-36781 Disease denotes lung inflammation MESH:D011014
942 37287-37297 Disease denotes infections MESH:D007239
943 37451-37471 Disease denotes bacterial infections MESH:D001424
948 38081-38084 Gene denotes Mir Gene:220972
949 38088-38096 Gene denotes Mir17-92 Gene:407975
950 38366-38380 Species denotes B. cenocepacia Tax:95486
951 38494-38506 Disease denotes lung disease MESH:D008171
982 39154-39159 Gene denotes Atg4b Gene:66615
983 39617-39621 Gene denotes LC3B Gene:67443
984 39623-39627 Gene denotes LC3B Gene:67443
985 40075-40083 Gene denotes Beclin-1 Gene:8678
986 40125-40130 Gene denotes TGFβ1 Gene:7040
987 39170-39174 Species denotes mice Tax:10090
988 39231-39235 Species denotes mice Tax:10090
989 39360-39364 Species denotes mice Tax:10090
990 39424-39428 Species denotes mice Tax:10090
991 39599-39603 Species denotes mice Tax:10090
992 39842-39846 Species denotes mice Tax:10090
993 39956-39962 Species denotes murine Tax:10090
994 40266-40272 Species denotes murine Tax:10090
995 38982-38991 Chemical denotes Bleomycin MESH:D001761
996 39113-39122 Chemical denotes bleomycin MESH:D001761
997 39204-39213 Chemical denotes bleomycin MESH:D001761
998 39403-39412 Chemical denotes bleomycin MESH:D001761
999 39633-39642 Chemical denotes bleomycin MESH:D001761
1000 39754-39763 Chemical denotes bleomycin MESH:D001761
1001 40248-40257 Chemical denotes bleomycin MESH:D001761
1002 40338-40353 Chemical denotes 3-methyladinine
1003 40355-40358 Chemical denotes 3MA
1004 38654-38667 Disease denotes dysfunctional MESH:D009461
1005 39034-39047 Disease denotes lung fibrosis MESH:D005355
1006 39131-39144 Disease denotes lung fibrosis MESH:D005355
1007 39454-39462 Disease denotes fibrosis MESH:D005355
1008 39652-39663 Disease denotes lung injury MESH:D055370
1009 39772-39783 Disease denotes lung injury MESH:D055370
1010 39817-39838 Disease denotes fibrotic lung disease MESH:D008171
1011 40208-40220 Disease denotes inflammation MESH:D007249
1024 40713-40723 Gene denotes annexin A2 Gene:302
1025 40725-40730 Gene denotes ANXA2 Gene:302
1026 40806-40810 Gene denotes TFEB Gene:7942
1027 40944-40948 Gene denotes TFEB Gene:7942
1028 41086-41091 Species denotes human Tax:9606
1029 41118-41126 Species denotes patients Tax:9606
1030 41670-41678 Species denotes patients Tax:9606
1031 40685-40694 Chemical denotes bleomycin MESH:D001761
1032 41000-41009 Chemical denotes bleomycin MESH:D001761
1033 40876-40897 Disease denotes fibrotic lung disease MESH:D008171
1034 41018-41036 Disease denotes pulmonary fibrosis MESH:D011658
1035 41203-41208 Disease denotes death MESH:D003643
1037 41703-41707 Gene denotes CFTR Gene:1080
1061 41760-41764 Gene denotes CFTR Gene:1080
1062 41850-41852 Gene denotes CS Gene:1431
1063 41905-41909 Gene denotes CFTR Gene:12638
1064 42020-42024 Gene denotes CFTR Gene:12638
1065 42057-42061 Gene denotes CFTR Gene:12638
1066 42108-42116 Gene denotes Beclin-1 Gene:56208
1067 42385-42389 Gene denotes CFTR Gene:12638
1068 42449-42453 Gene denotes CFTR Gene:12638
1069 42681-42685 Gene denotes CFTR Gene:12638
1070 42943-42947 Gene denotes NFκB Gene:4790
1071 43579-43582 Gene denotes LC3 Gene:84557
1072 42104-42107 Gene denotes TG2 Gene:21817
1073 42514-42516 Gene denotes CS Gene:1431
1074 42229-42231 Gene denotes CS Gene:1431
1075 41920-41924 Species denotes mice Tax:10090
1076 42289-42297 Chemical denotes ceramide MESH:D002518
1077 42464-42484 Chemical denotes S-nitrosoglutathione MESH:D026422
1078 42486-42490 Chemical denotes GSNO
1079 42240-42256 Disease denotes CFTR dysfunction MESH:D009461
1080 42316-42330 Disease denotes COPD-emphysema MESH:D029424
1081 42582-42596 Disease denotes COPD-emphysema MESH:D029424
1082 42779-42799 Disease denotes chronic lung disease MESH:D055370
1083 43046-43062 Disease denotes CFTR dysfunction MESH:D009461
1097 44230-44235 Gene denotes IL-1β Gene:3552
1098 44240-44245 Gene denotes IL-18 Gene:3606
1099 44565-44569 Gene denotes LC3B Gene:81631
1100 44573-44581 Gene denotes Beclin-1 Gene:8678
1101 44591-44596 Gene denotes NLRP3 Gene:114548
1102 44780-44784 Gene denotes NFκB Gene:4790
1103 45093-45096 Gene denotes CD4 Gene:920
1104 45107-45110 Gene denotes CD8 Gene:925
1105 45386-45389 Gene denotes CD8 Gene:925
1106 44742-44754 Disease denotes inflammation MESH:D007249
1107 44919-44930 Disease denotes lung injury MESH:D055370
1108 45649-45658 Disease denotes infection MESH:D007239
1109 45797-45807 Disease denotes infections MESH:D007239
1135 45832-45836 Gene denotes CFTR Gene:1080
1136 46054-46058 Gene denotes CFTR Gene:1080
1137 46867-46871 Gene denotes CFTR Gene:1080
1138 47046-47049 Gene denotes MPO Gene:4353
1139 47054-47073 Gene denotes neutrophil elastase Gene:1991
1140 47225-47228 Gene denotes MPO Gene:4353
1141 47399-47403 Gene denotes CFTR Gene:1080
1142 47434-47438 Gene denotes CFTR Gene:1080
1143 47556-47560 Gene denotes CFTR Gene:1080
1144 47656-47662 Gene denotes Rab27a Gene:5873
1145 47781-47785 Gene denotes CFTR Gene:1080
1146 47806-47810 Gene denotes CFTR Gene:1080
1147 47894-47898 Gene denotes NFκB Gene:4790
1148 46225-46229 Chemical denotes Treg
1149 46270-46273 Chemical denotes Th2
1150 46807-46815 Chemical denotes chloride MESH:D002712
1151 47311-47342 Chemical denotes suberoylanilide hydroxamic acid MESH:D000077337
1152 47611-47633 Chemical denotes guanosine triphosphate MESH:D006160
1153 47635-47638 Chemical denotes GTP MESH:D006160
1154 46175-46190 Disease denotes CFTR deficiency MESH:D007153
1155 46308-46317 Disease denotes CF defect MESH:D003550
1156 46942-46956 Disease denotes CF neutrophils MESH:D003550
1157 47166-47178 Disease denotes inflammation MESH:D007249
1158 47202-47216 Disease denotes aeruginosa LPS MESH:C536528
1159 47677-47704 Disease denotes impaired granule exocytosis MESH:C531691
1165 47971-47975 Gene denotes CFTR Gene:1080
1166 48101-48105 Gene denotes CFTR Gene:1080
1167 48058-48068 Disease denotes infections MESH:D007239
1168 48148-48166 Disease denotes immune dysfunction MESH:D007154
1169 48188-48200 Disease denotes lung disease MESH:D008171
1171 48240-48244 Gene denotes CFTR Gene:1080
1180 48322-48330 Species denotes patients Tax:9606
1181 48705-48712 Species denotes patient Tax:9606
1182 48901-48909 Species denotes patients Tax:9606
1183 48344-48364 Disease denotes respiratory diseases MESH:D012140
1184 48373-48377 Disease denotes COPD MESH:D029424
1185 48644-48660 Disease denotes viral infections MESH:D001102
1186 48820-48829 Disease denotes mortality MESH:D003643
1187 48923-48943 Disease denotes respiratory diseases MESH:D012140
1205 49372-49376 Gene denotes CFTR Gene:1080
1206 49809-49813 Gene denotes CFTR Gene:1080
1207 49982-49986 Gene denotes CFTR Gene:1080
1208 50069-50073 Gene denotes CFTR Gene:1080
1209 50277-50281 Gene denotes CFTR Gene:1080
1210 49294-49307 Species denotes P. aeruginosa Tax:287
1211 49468-49476 Species denotes patients Tax:9606
1212 50101-50114 Species denotes P. aeruginosa Tax:287
1213 50358-50371 Species denotes P. aeruginosa Tax:287
1214 50193-50200 Chemical denotes fisetin MESH:C017875
1215 49015-49025 Disease denotes infections MESH:D007239
1216 49240-49260 Disease denotes respiratory diseases MESH:D012140
1217 49417-49438 Disease denotes aeruginosa infections MESH:D011552
1218 49636-49657 Disease denotes aeruginosa infections MESH:D011552
1219 49722-49738 Disease denotes CFTR dysfunction MESH:D009461
1220 50315-50328 Disease denotes lung diseases MESH:D008171
1221 50344-50348 Disease denotes COPD MESH:D029424
1233 50642-50646 Gene denotes CFTR Gene:1080
1234 50799-50803 Gene denotes CFTR Gene:1080
1235 50945-50949 Gene denotes CFTR Gene:1080
1236 50420-50430 Species denotes B. cepacia Tax:292
1237 50485-50493 Species denotes patients Tax:9606
1238 50572-50582 Species denotes B. cepacia Tax:292
1239 50782-50791 Chemical denotes rapamycin MESH:D020123
1240 50436-50459 Disease denotes opportunistic infection MESH:D009894
1241 50842-50859 Disease denotes cepacia infection MESH:D019121
1242 50885-50897 Disease denotes inflammation MESH:D007249
1243 51062-51074 Disease denotes inflammation MESH:D007249
1259 51156-51160 Gene denotes CFTR Gene:1080
1260 51257-51261 Gene denotes CFTR Gene:12638
1261 51456-51460 Gene denotes CFTR Gene:1080
1262 51577-51581 Gene denotes CFTR Gene:1080
1263 51725-51729 Gene denotes CFTR Gene:1080
1264 51819-51823 Gene denotes CFTR Gene:1080
1265 51272-51276 Species denotes mice Tax:10090
1266 51357-51361 Species denotes mice Tax:10090
1267 51504-51514 Species denotes rhinovirus Tax:12059
1268 51760-51770 Species denotes rhinovirus Tax:12059
1269 51416-51427 Species denotes respiratory Tax:12814
1270 51291-51294 Species denotes RSV Tax:12814
1271 51138-51154 Disease denotes viral infections MESH:D001102
1272 51277-51285 Disease denotes infected MESH:D007239
1273 51490-51498 Disease denotes infected MESH:D007239
1285 51956-51960 Gene denotes CFTR Gene:1080
1286 52133-52137 Gene denotes CFTR Gene:1080
1287 52299-52303 Gene denotes CFTR Gene:1080
1288 52388-52390 Gene denotes CS Gene:1431
1289 52285-52293 Species denotes patients Tax:9606
1290 52337-52345 Species denotes patients Tax:9606
1291 52102-52110 Chemical denotes ceramide MESH:D002518
1292 52234-52242 Chemical denotes Ceramide MESH:D002518
1293 51945-51954 Disease denotes infection MESH:D007239
1294 52332-52336 Disease denotes COPD MESH:D029424
1295 52364-52380 Disease denotes CFTR dysfunction MESH:D009461
1308 52474-52477 Gene denotes p62 Gene:51164
1309 52538-52542 Gene denotes CFTR Gene:1080
1310 52859-52863 Gene denotes CFTR Gene:1080
1311 52429-52431 Gene denotes CS Gene:1431
1312 52433-52441 Chemical denotes ceramide MESH:D002518
1313 52647-52650 Chemical denotes ROS MESH:D017382
1314 52834-52842 Chemical denotes ceramide MESH:D002518
1315 52986-52994 Chemical denotes ceramide MESH:D002518
1316 52585-52589 Disease denotes COPD MESH:D029424
1317 52763-52783 Disease denotes respiratory diseases MESH:D012140
1318 53051-53067 Disease denotes CFTR dysfunction MESH:D009461
1319 53191-53209 Disease denotes dysfunctional CFTR MESH:D009461
1322 53413-53417 Gene denotes CFTR Gene:1080
1323 53461-53494 Disease denotes Chronic Obstructive Lung Diseases MESH:D029424
1400 53874-53878 Gene denotes CFTR Gene:1080
1401 54397-54420 Gene denotes transcription factor-EB Gene:7942
1402 54422-54426 Gene denotes TFEB Gene:7942
1403 54618-54622 Gene denotes TFEB Gene:7942
1404 54971-54975 Gene denotes TFEB Gene:7942
1405 55092-55096 Gene denotes TFEB Gene:7942
1406 55164-55166 Gene denotes CS Gene:1431
1407 55232-55236 Gene denotes TFEB Gene:7942
1408 55368-55372 Gene denotes CFTR Gene:1080
1409 55582-55586 Gene denotes CFTR Gene:1080
1410 56094-56098 Gene denotes CFTR Gene:1080
1411 56492-56496 Gene denotes CFTR Gene:1080
1412 56833-56837 Gene denotes CFTR Gene:1080
1413 56845-56847 Gene denotes CS Gene:1431
1414 57009-57013 Gene denotes CFTR Gene:1080
1415 57404-57408 Gene denotes CFTR Gene:1080
1416 57711-57715 Gene denotes CFTR Gene:1080
1417 57736-57739 Gene denotes ASM Gene:6609
1418 58119-58140 Gene denotes acid sphingomyelinase Gene:6609
1419 58142-58145 Gene denotes ASM Gene:6609
1420 58221-58224 Gene denotes ASM Gene:20597
1421 58424-58428 Gene denotes CFTR Gene:1080
1422 56181-56183 Gene denotes CS Gene:1431
1423 57560-57562 Gene denotes CS Gene:1431
1424 57243-57245 Gene denotes CS Gene:1431
1425 57029-57031 Gene denotes CS Gene:1431
1426 56527-56529 Gene denotes CS Gene:1431
1427 55949-55951 Gene denotes CS Gene:1431
1428 54579-54581 Gene denotes CS Gene:1431
1429 53636-53638 Gene denotes CS Gene:1431
1430 54865-54870 Species denotes human Tax:9606
1431 58032-58036 Species denotes mice Tax:10090
1432 58041-58049 Species denotes patients Tax:9606
1433 58367-58371 Species denotes mice Tax:10090
1434 53910-53913 Chemical denotes ROS MESH:D017382
1435 53914-53917 Chemical denotes RNS MESH:D011886
1436 55620-55623 Chemical denotes ROS MESH:D017382
1437 55695-55703 Chemical denotes ceramide MESH:D002518
1438 56734-56742 Chemical denotes ceramide MESH:D002518
1439 56881-56889 Chemical denotes ceramide MESH:D002518
1440 56998-57003 Chemical denotes lipid MESH:D008055
1441 57123-57131 Chemical denotes ceramide MESH:D002518
1442 57135-57151 Chemical denotes lactosylceramide MESH:C009744
1443 57272-57280 Chemical denotes ceramide MESH:D002518
1444 57662-57670 Chemical denotes ceramide MESH:D002518
1445 57770-57778 Chemical denotes ceramide MESH:D002518
1446 57821-57829 Chemical denotes ceramide MESH:D002518
1447 58091-58094 Chemical denotes ROS MESH:D017382
1448 58178-58186 Chemical denotes ceramide MESH:D002518
1449 58278-58286 Chemical denotes ceramide MESH:D002518
1450 53806-53813 Disease denotes obesity MESH:D009765
1451 54249-54263 Disease denotes COPD-emphysema MESH:D029424
1452 54304-54313 Disease denotes emphysema MESH:D004646
1453 54317-54321 Disease denotes COPD MESH:D029424
1454 54918-54922 Disease denotes COPD MESH:D029424
1455 55013-55022 Disease denotes emphysema MESH:D004646
1456 55489-55513 Disease denotes obstructive lung disease MESH:D008173
1457 55807-55827 Disease denotes pulmonary infections MESH:D012141
1458 56150-56166 Disease denotes CFTR dysfunction MESH:D009461
1459 56274-56290 Disease denotes CFTR dysfunction MESH:D009461
1460 56294-56298 Disease denotes COPD MESH:D029424
1461 56380-56396 Disease denotes CFTR dysfunction MESH:D009461
1462 56400-56404 Disease denotes COPD MESH:D029424
1463 56595-56609 Disease denotes COPD-emphysema MESH:D029424
1464 56716-56730 Disease denotes COPD-emphysema MESH:D029424
1465 57104-57118 Disease denotes COPD-emphysema MESH:D029424
1466 57254-57270 Disease denotes CFTR dysfunction MESH:D009461
1467 57332-57346 Disease denotes COPD-emphysema MESH:D029424
1468 57495-57508 Disease denotes lung diseases MESH:D008171
1469 57858-57873 Disease denotes CF lung disease MESH:D003550
1470 57899-57911 Disease denotes inflammation MESH:D007249
1471 57959-57979 Disease denotes aeruginosa infection MESH:D011552
1472 58321-58330 Disease denotes infection MESH:D007239
1473 58335-58347 Disease denotes inflammation MESH:D007249
1474 58574-58583 Disease denotes infection MESH:D007239
1475 58638-58670 Disease denotes chronic obstructive lung disease MESH:D029424
1477 58771-58804 Disease denotes Chronic Obstructive Lung Diseases MESH:D029424
1500 60427-60431 Gene denotes CFTR Gene:1080
1501 59313-59319 Species denotes murine Tax:10090
1502 59784-59790 Species denotes murine Tax:10090
1503 59937-59947 Chemical denotes cysteamine MESH:D003543
1504 59984-59994 Chemical denotes aminothiol
1505 60304-60314 Chemical denotes cysteamine MESH:D003543
1506 61032-61042 Chemical denotes cysteamine MESH:D003543
1507 58835-58851 Disease denotes CFTR dysfunction MESH:D009461
1508 58905-58938 Disease denotes chronic obstructive lung diseases MESH:D029424
1509 58973-58983 Disease denotes infections MESH:D007239
1510 59049-59058 Disease denotes mortality MESH:D003643
1511 59155-59171 Disease denotes CFTR dysfunction MESH:D009461
1512 59225-59258 Disease denotes chronic obstructive lung diseases MESH:D029424
1513 59430-59443 Disease denotes lung diseases MESH:D008171
1514 59553-59569 Disease denotes viral infections MESH:D001102
1515 59684-59700 Disease denotes CFTR dysfunction MESH:D009461
1516 59833-59856 Disease denotes aeruginosa co-infection MESH:D060085
1517 60248-60259 Disease denotes lung injury MESH:D055370
1518 60265-60279 Disease denotes COPD-emphysema MESH:D029424
1519 60489-60505 Disease denotes CFTR dysfunction MESH:D009461
1520 61122-61136 Disease denotes COPD-emphysema MESH:D029424
1521 61282-61306 Disease denotes obstructive lung disease MESH:D008173
1550 61711-61715 Gene denotes CFTR Gene:1080
1551 61910-61914 Gene denotes CFTR Gene:12638
1552 62262-62266 Gene denotes CFTR Gene:12638
1553 62587-62591 Gene denotes TFEB Gene:7942
1554 62722-62726 Gene denotes TFEB Gene:7942
1555 61436-61438 Gene denotes CS Gene:1431
1556 61584-61599 Gene denotes cigarette smoke Gene:1431
1557 61780-61786 Species denotes murine Tax:10090
1558 62934-62947 Species denotes P. aeruginosa Tax:287
1559 63070-63083 Species denotes P. aeruginosa Tax:287
1560 61342-61346 Chemical denotes GSNO
1561 61374-61386 Chemical denotes nitric oxide MESH:D009569
1562 61569-61573 Chemical denotes GSNO
1563 62099-62103 Chemical denotes GSNO
1564 62174-62178 Chemical denotes GSNO
1565 62297-62307 Chemical denotes cysteamine MESH:D003543
1566 62312-62316 Chemical denotes GSNO
1567 62403-62414 Chemical denotes gemfibrozil MESH:D015248
1568 62416-62419 Chemical denotes GEM MESH:D015248
1569 62706-62709 Chemical denotes GEM MESH:D015248
1570 62710-62717 Chemical denotes fisetin MESH:C017875
1571 62992-62999 Chemical denotes fisetin MESH:C017875
1572 61447-61463 Disease denotes CFTR dysfunction MESH:D009461
1573 61506-61520 Disease denotes COPD-emphysema MESH:D029424
1574 61765-61779 Disease denotes COPD-emphysema MESH:D029424
1575 62871-62891 Disease denotes phagocytosis defects MESH:D000014
1576 63035-63054 Disease denotes phagocytosis defect MESH:D000014
1577 63200-63214 Disease denotes COPD-emphysema MESH:D029424
1602 63720-63723 Gene denotes Tα1 Gene:134864
1603 63825-63829 Gene denotes CFTR Gene:1080
1604 63847-63850 Gene denotes Tα1 Gene:134864
1605 63990-63994 Gene denotes CFTR Gene:1080
1606 64464-64468 Gene denotes CFTR Gene:1080
1607 64520-64524 Gene denotes CFTR Gene:1080
1608 64356-64361 Species denotes human Tax:9606
1609 64440-64448 Species denotes patients Tax:9606
1610 64820-64826 Species denotes murine Tax:10090
1611 63460-63469 Chemical denotes rapamycin MESH:D020123
1612 64181-64191 Chemical denotes cysteamine MESH:D003543
1613 64539-64549 Chemical denotes cysteamine MESH:D003543
1614 64607-64617 Chemical denotes cysteamine MESH:D003543
1615 64714-64724 Chemical denotes cysteamine MESH:D003543
1616 64795-64803 Chemical denotes ceramide MESH:D002518
1617 64978-64986 Chemical denotes ceramide MESH:D002518
1618 63330-63353 Disease denotes chronic CF lung disease MESH:D003550
1619 63369-63388 Disease denotes pulmonary infection MESH:D012141
1620 63496-63511 Disease denotes lung infections MESH:D012141
1621 63626-63639 Disease denotes lung toxicity MESH:D008171
1622 64896-64900 Disease denotes COPD MESH:D029424
1623 64905-64926 Disease denotes CF-related infections MESH:D003550
1624 65000-65020 Disease denotes pulmonary infections MESH:D012141
1625 65024-65028 Disease denotes COPD MESH:D029424
1630 65594-65602 Gene denotes Beclin-1 Gene:56208
1631 65567-65573 Species denotes murine Tax:10090
1632 65509-65518 Chemical denotes bleomycin MESH:D001761
1633 65527-65539 Disease denotes inflammation MESH:D007249
1637 65848-65855 Species denotes patient Tax:9606
1638 65717-65749 Disease denotes chronic obstructive lung disease MESH:D029424
1639 65856-65865 Disease denotes mortality MESH:D003643
1646 66744-66748 Gene denotes CFTR Gene:1080
1647 65982-65990 Species denotes patients Tax:9606
1648 66180-66187 Species denotes patient Tax:9606
1649 66355-66363 Species denotes patients Tax:9606
1650 66638-66646 Species denotes patients Tax:9606
1651 65996-66000 Disease denotes COPD MESH:D029424
1668 66946-66950 Gene denotes CFTR Gene:1080
1669 67510-67514 Gene denotes CFTR Gene:1080
1670 67543-67547 Gene denotes CFTR Gene:1080
1671 67701-67709 Gene denotes Beclin-1 Gene:8678
1672 67809-67813 Gene denotes CFTR Gene:1080
1673 67456-67469 Species denotes P. aeruginosa Tax:287
1674 67681-67694 Species denotes P. aeruginosa Tax:287
1675 67843-67851 Species denotes patients Tax:9606
1676 67922-67935 Species denotes P. aeruginosa Tax:287
1677 67942-67950 Species denotes patients Tax:9606
1678 67169-67179 Chemical denotes cysteamine MESH:D003543
1679 67181-67191 Chemical denotes Cysteamine MESH:D003543
1680 67426-67436 Chemical denotes cysteamine MESH:D003543
1681 67237-67247 Disease denotes cystinosis MESH:D003554
1682 67872-67895 Disease denotes aeruginosa colonization MESH:D003110
1683 68003-68024 Disease denotes aeruginosa infections MESH:D011552
1699 68323-68327 Gene denotes CFTR Gene:1080
1700 68479-68483 Gene denotes CFTR Gene:1080
1701 68575-68579 Gene denotes CFTR Gene:1080
1702 68619-68623 Gene denotes CFTR Gene:1080
1703 68704-68717 Species denotes P. aeruginosa Tax:287
1704 68949-68962 Species denotes P. aeruginosa Tax:287
1705 69034-69042 Species denotes patients Tax:9606
1706 68161-68171 Chemical denotes cysteamine MESH:D003543
1707 68258-68268 Chemical denotes cysteamine MESH:D003543
1708 68751-68761 Chemical denotes cysteamine MESH:D003543
1709 68872-68882 Chemical denotes Cysteamine MESH:D003543
1710 69006-69016 Disease denotes infections MESH:D007239
1711 69150-69170 Disease denotes respiratory diseases MESH:D012140
1712 69192-69208 Disease denotes CFTR dysfunction MESH:D009461
1713 69291-69301 Disease denotes infections MESH:D007239
1720 69811-69815 Gene denotes CFTR Gene:1080
1721 69919-69923 Gene denotes CFTR Gene:1080
1722 70125-70130 Species denotes human Tax:9606
1723 69515-69524 Chemical denotes rapamycin MESH:D020123
1724 69665-69672 Chemical denotes fisetin MESH:C017875
1725 69418-69438 Disease denotes respiratory diseases MESH:D012140
1734 70237-70241 Gene denotes CFTR Gene:1080
1735 70413-70421 Species denotes patients Tax:9606
1736 70774-70782 Species denotes patients Tax:9606
1737 70839-70846 Species denotes patient Tax:9606
1738 70854-70861 Species denotes patient Tax:9606
1739 70957-70965 Species denotes patients Tax:9606
1740 70993-71003 Disease denotes infections MESH:D007239
1741 71214-71224 Disease denotes infections MESH:D007239
1752 71939-71943 Gene denotes CFTR Gene:1080
1753 72137-72141 Gene denotes CFTR Gene:1080
1754 71575-71583 Species denotes patients Tax:9606
1755 71674-71688 Species denotes B. cenocepacia Tax:95486
1756 71690-71704 Species denotes B. multivorans Tax:87883
1757 71710-71723 Species denotes P. aeruginosa Tax:287
1758 71480-71490 Chemical denotes cysteamine MESH:D003543
1759 71761-71771 Chemical denotes cysteamine MESH:D003543
1760 71867-71877 Chemical denotes cysteamine MESH:D003543
1761 72017-72027 Chemical denotes cysteamine MESH:D003543
1771 72772-72776 Gene denotes CFTR Gene:1080
1772 72448-72469 Species denotes Staphylococcus aureus Tax:1280
1773 72474-72487 Species denotes P. aeruginosa Tax:287
1774 72556-72570 Species denotes B. cenocepacia Tax:95486
1775 72294-72299 Chemical denotes AR-13
1776 72351-72353 Chemical denotes AR MESH:D001128
1777 72426-72437 Chemical denotes methicillin MESH:D008712
1778 72572-72577 Chemical denotes AR-13
1779 72673-72681 Disease denotes infected MESH:D007239
1783 72846-72850 Gene denotes CFTR Gene:1080
1784 72906-72916 Disease denotes infections MESH:D007239
1785 73170-73189 Disease denotes respiratory disease MESH:D012140
1791 73628-73636 Species denotes patients Tax:9606
1792 73650-73670 Disease denotes respiratory diseases MESH:D012140
1793 73854-73863 Disease denotes infection MESH:D007239
1794 74139-74155 Disease denotes viral infections MESH:D001102
1795 74187-74203 Disease denotes viral infections MESH:D001102
1814 74499-74509 Species denotes Rhinovirus Tax:12059
1815 74718-74728 Species denotes rhinovirus Tax:12059
1816 74732-74740 Species denotes patients Tax:9606
1817 75102-75112 Species denotes rhinovirus Tax:12059
1818 75230-75240 Species denotes rhinovirus Tax:12059
1819 75423-75431 Species denotes patients Tax:9606
1820 74426-74436 Chemical denotes budesonide MESH:D019819
1821 74679-74689 Chemical denotes budesonide MESH:D019819
1822 74808-74818 Chemical denotes budesonide MESH:D019819
1823 74879-74890 Chemical denotes chloroquine MESH:D002738
1824 74895-74909 Chemical denotes bafilomycin A1 MESH:C040929
1825 74961-74971 Chemical denotes budesonide MESH:D019819
1826 75013-75026 Chemical denotes dexamethasone MESH:D003907
1827 74476-74497 Disease denotes rhinovirus infections MESH:D007239
1828 74528-74532 Disease denotes cold MESH:D000067390
1829 74594-74600 Disease denotes asthma MESH:D001249
1830 74615-74619 Disease denotes COPD MESH:D029424
1831 75445-75464 Disease denotes respiratory disease MESH:D012140
1850 76946-76949 Gene denotes AKT Gene:207
1851 76981-76989 Gene denotes Beclin-1 Gene:8678
1852 75752-75769 Species denotes novel coronavirus Tax:2697049
1853 75770-75779 Species denotes SARS-CoV2 Tax:2697049
1854 75789-75794 Species denotes human Tax:9606
1855 75973-75983 Species denotes SARS-CoV-2 Tax:2697049
1856 76082-76092 Chemical denotes remdesevir
1857 76094-76105 Chemical denotes favipiravir MESH:C462182
1858 76899-76909 Chemical denotes spermidine MESH:D013095
1859 76934-76941 Chemical denotes MK-2206 MESH:C548887
1860 76966-76977 Chemical denotes niclosamide MESH:D009534
1861 75795-75816 Disease denotes respiratory infection MESH:D012141
1862 75829-75837 Disease denotes COVID-19 MESH:C000657245
1863 76004-76010 Disease denotes deaths MESH:D003643
1864 76189-76201 Disease denotes lung disease MESH:D008171
1865 76401-76410 Disease denotes mortality MESH:D003643
1866 77022-77030 Disease denotes COVID-19 MESH:C000657245
1867 77386-77394 Disease denotes COVID-19 MESH:C000657245
1879 77825-77829 Gene denotes CFTR Gene:1080
1880 77963-77971 Species denotes patients Tax:9606
1881 79254-79262 Species denotes patients Tax:9606
1882 79155-79166 Species denotes respiratory Tax:12814
1883 77873-77893 Disease denotes respiratory diseases MESH:D012140
1884 77949-77958 Disease denotes mortality MESH:D003643
1885 78252-78272 Disease denotes bacterial infections MESH:D001424
1886 78282-78298 Disease denotes viral infections MESH:D001102
1887 78748-78758 Disease denotes infections MESH:D007239
1888 78893-78913 Disease denotes respiratory diseases MESH:D012140
1889 79241-79250 Disease denotes mortality MESH:D003643
1895 79935-79939 Gene denotes CFTR Gene:1080
1896 80165-80172 Gene denotes BIOTECH Gene:57449
1897 80225-80236 Species denotes respiratory Tax:12814
1898 79970-79985 Disease denotes CF lung disease MESH:D003550
1899 80096-80109 Disease denotes lung diseases MESH:D008171
2790 80462-80513 Gene denotes cystic fibrosis transmembrane conductance regulator Gene:1080
2791 80515-80519 Gene denotes CFTR Gene:1080
2792 80670-80674 Gene denotes CFTR Gene:1080
2793 80733-80737 Gene denotes CFTR Gene:1080
2794 80745-80749 Gene denotes CFTR Gene:1080
2795 81154-81162 Gene denotes Beclin-1 Gene:8678
2796 81169-81177 Gene denotes Beclin-1 Gene:8678
2797 81642-81646 Gene denotes ACE2 Gene:59272
2798 81656-81663 Gene denotes TMPRSS2 Gene:7113
2799 81109-81112 Gene denotes TG2 Gene:21817
2800 81607-81617 Species denotes SARS-CoV-2 Tax:2697049
2801 80363-80374 Species denotes respiratory Tax:12814
2802 80534-80539 Chemical denotes lipid MESH:D008055
2803 80807-80830 Chemical denotes reactive oxygen species MESH:D017382
2804 80832-80835 Chemical denotes ROS MESH:D017382
2805 81045-81053 Chemical denotes ceramide MESH:D002518
2806 81460-81463 Chemical denotes ROS MESH:D017382
2807 80393-80405 Disease denotes lung disease MESH:D008171
2808 80592-80611 Disease denotes bacterial infection MESH:D001424
2809 80676-80713 Disease denotes chronic obstructive pulmonary disease MESH:D029424
2810 80715-80719 Disease denotes COPD MESH:D029424
2811 80751-80766 Disease denotes cystic fibrosis MESH:D003550
2812 81505-81525 Disease denotes chronic lung disease MESH:D055370
2813 81559-81569 Disease denotes infections MESH:D007239
2814 81582-81598 Disease denotes viral infections MESH:D001102
2815 81903-81915 Disease denotes inflammation MESH:D007249
2816 81944-81956 Disease denotes lung disease MESH:D008171
2817 81004-81014 Mutation denotes ΔF508 CFTR c.508DELTA>CFTR
2829 82070-82081 Species denotes respiratory Tax:12814
2830 82519-82530 Species denotes respiratory Tax:12814
2831 82100-82124 Disease denotes coronavirus disease-2019 MESH:C000657245
2832 82126-82134 Disease denotes COVID-19 MESH:C000657245
2833 82228-82249 Disease denotes pulmonary pathologies MESH:D008171
2834 82340-82358 Disease denotes dysfunctional CFTR MESH:D009461
2835 82842-82846 Disease denotes COPD MESH:D029424
2836 82852-82887 Disease denotes acute respiratory distress syndrome MESH:D012128
2837 82889-82893 Disease denotes ARDS MESH:D012128
2838 82896-82925 Disease denotes idiopathic pulmonary fibrosis MESH:D054990
2839 82937-82945 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 571-584 Phenotype denotes lung diseases http://purl.obolibrary.org/obo/HP_0002088
T2 594-631 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T3 633-637 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T4 673-691 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T5 699-716 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T6 718-721 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T7 730-750 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T8 1144-1164 Phenotype denotes chronic lung disease http://purl.obolibrary.org/obo/HP_0006528
T9 1422-1447 Phenotype denotes restrictive lung diseases http://purl.obolibrary.org/obo/HP_0002091
T10 1608-1620 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T11 1777-1802 Phenotype denotes restrictive lung diseases http://purl.obolibrary.org/obo/HP_0002091
T12 1852-1856 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T13 1862-1865 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T14 1926-1951 Phenotype denotes restrictive lung diseases http://purl.obolibrary.org/obo/HP_0002091
T15 2975-3012 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T16 3014-3018 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T17 3043-3060 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T18 3062-3065 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T19 3074-3094 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T20 3155-3163 Phenotype denotes plethora http://purl.obolibrary.org/obo/HP_0001050
T21 5416-5442 Phenotype denotes neurodegenerative diseases http://purl.obolibrary.org/obo/HP_0002180
T22 5515-5519 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T23 5541-5563 Phenotype denotes Respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T24 5689-5693 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T25 5694-5703 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T26 5942-5958 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T27 6006-6010 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T28 6011-6020 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T29 6217-6249 Phenotype denotes recurrent respiratory infections http://purl.obolibrary.org/obo/HP_0002205
T30 6489-6512 Phenotype denotes infections or recurrent http://purl.obolibrary.org/obo/HP_0002719
T31 6743-6763 Phenotype denotes chronic lung disease http://purl.obolibrary.org/obo/HP_0006528
T32 6841-6861 Phenotype denotes pulmonary infections http://purl.obolibrary.org/obo/HP_0006532
T33 7287-7291 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T34 7292-7301 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T35 7779-7789 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T36 7857-7876 Phenotype denotes pulmonary infection http://purl.obolibrary.org/obo/HP_0006532
T37 7892-7902 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T38 8673-8687 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T39 8741-8753 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T40 8830-8846 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T41 9637-9642 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T42 9890-9902 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T43 11418-11422 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T44 11543-11559 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T45 11667-11671 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T46 11833-11837 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T47 11872-11896 Phenotype denotes opportunistic infections http://purl.obolibrary.org/obo/HP_0031690
T48 12095-12099 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T49 12101-12104 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T50 12178-12198 Phenotype denotes pulmonary infections http://purl.obolibrary.org/obo/HP_0006532
T51 12309-12321 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T52 12394-12415 Phenotype denotes Respiratory Infection http://purl.obolibrary.org/obo/HP_0011947
T53 13585-13595 Phenotype denotes granulomas http://purl.obolibrary.org/obo/HP_0032252
T54 14012-14022 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T55 14027-14037 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T56 14101-14110 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T57 14324-14334 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T58 14497-14506 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T59 14652-14662 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T60 20486-20490 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T61 20957-20973 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T62 21020-21040 Phenotype denotes recurrent infections http://purl.obolibrary.org/obo/HP_0002719
T63 21534-21559 Phenotype denotes restrictive lung diseases http://purl.obolibrary.org/obo/HP_0002091
T64 21569-21573 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T65 21574-21583 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T66 21613-21631 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T67 21964-21981 Phenotype denotes Acute Lung Injury http://www.orpha.net/ORDO/Orphanet_178320
T68 21983-21986 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T69 22052-22069 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T70 22149-22165 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T71 22429-22432 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T72 22480-22486 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T73 22599-22616 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T74 22725-22735 Phenotype denotes lung edema http://purl.obolibrary.org/obo/HP_0100598
T75 23348-23367 Phenotype denotes acute lung injuries http://www.orpha.net/ORDO/Orphanet_178320
T76 23486-23492 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T77 23632-23649 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T78 23700-23706 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T79 23797-23800 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T80 23858-23861 Phenotype denotes BPD http://purl.obolibrary.org/obo/HP_0012076
T81 24006-24009 Phenotype denotes BPD http://purl.obolibrary.org/obo/HP_0012076
T82 24533-24536 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T83 24616-24619 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T84 24654-24674 Phenotype denotes Respiratory Distress http://purl.obolibrary.org/obo/HP_0002098
T85 24712-24715 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T86 24738-24758 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T87 25022-25025 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T88 25307-25313 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T89 25322-25325 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T90 25464-25467 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T91 25869-25872 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T92 26030-26033 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T93 26450-26459 Phenotype denotes hypoxemia http://purl.obolibrary.org/obo/HP_0012418
T94 26511-26514 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T95 26596-26599 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T96 26721-26724 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T97 27353-27367 Phenotype denotes cytokine-storm http://purl.obolibrary.org/obo/HP_0033041
T98 27379-27388 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T99 27463-27475 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T100 27641-27653 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T101 29613-29633 Phenotype denotes rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0001370
T102 30188-30202 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T103 30260-30272 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T104 30634-30647 Phenotype denotes lung diseases http://purl.obolibrary.org/obo/HP_0002088
T105 31037-31051 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T106 31867-31871 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T107 32066-32070 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T108 32071-32080 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T109 32218-32222 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T110 32223-32232 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T111 32851-32860 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T112 32937-32941 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T113 32942-32951 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T114 33019-33028 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T115 33213-33217 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T116 33218-33227 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T117 33354-33358 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T118 33359-33368 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T119 33498-33510 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T120 33553-33557 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T121 33558-33567 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T122 33590-33606 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T123 34004-34020 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T124 34435-34439 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T125 34440-34449 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T126 34657-34661 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T127 34662-34671 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T128 34835-34839 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T129 35943-35947 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T130 36130-36134 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T131 36374-36378 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T132 36461-36485 Phenotype denotes obstructive lung disease http://purl.obolibrary.org/obo/HP_0006536
T133 36505-36525 Phenotype denotes recurrent infections http://purl.obolibrary.org/obo/HP_0002719
T134 36548-36564 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T135 37279-37297 Phenotype denotes chronic infections http://purl.obolibrary.org/obo/HP_0031035
T136 37325-37341 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T137 37442-37471 Phenotype denotes prone to bacterial infections http://purl.obolibrary.org/obo/HP_0002718
T138 38494-38506 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T139 39826-39838 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T140 40885-40897 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T141 41018-41036 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T142 42271-42287 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T143 42316-42320 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T144 42321-42330 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T145 42561-42577 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T146 42582-42586 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T147 42587-42596 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T148 42779-42799 Phenotype denotes chronic lung disease http://purl.obolibrary.org/obo/HP_0006528
T149 42886-42902 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T150 46570-46578 Phenotype denotes plethora http://purl.obolibrary.org/obo/HP_0001050
T151 48180-48200 Phenotype denotes chronic lung disease http://purl.obolibrary.org/obo/HP_0006528
T152 48373-48377 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T153 50307-50328 Phenotype denotes chronic lung diseases http://purl.obolibrary.org/obo/HP_0006528
T154 50344-50348 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T155 50436-50459 Phenotype denotes opportunistic infection http://purl.obolibrary.org/obo/HP_0031690
T156 52332-52336 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T157 52585-52589 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T158 53332-53354 Phenotype denotes decrease lung function http://purl.obolibrary.org/obo/HP_0005952
T159 53469-53494 Phenotype denotes Obstructive Lung Diseases http://purl.obolibrary.org/obo/HP_0006536
T160 53806-53813 Phenotype denotes obesity http://purl.obolibrary.org/obo/HP_0001513
T161 54105-54121 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T162 54249-54253 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T163 54254-54263 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T164 54304-54313 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T165 54317-54321 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T166 54918-54922 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T167 55013-55022 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T168 55489-55513 Phenotype denotes obstructive lung disease http://purl.obolibrary.org/obo/HP_0006536
T169 55646-55662 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T170 55807-55827 Phenotype denotes pulmonary infections http://purl.obolibrary.org/obo/HP_0006532
T171 56214-56230 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T172 56294-56298 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T173 56400-56404 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T174 56551-56567 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T175 56595-56599 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T176 56600-56609 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T177 56716-56720 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T178 56721-56730 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T179 57104-57108 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T180 57109-57118 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T181 57332-57336 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T182 57337-57346 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T183 57487-57508 Phenotype denotes chronic lung diseases http://purl.obolibrary.org/obo/HP_0006528
T184 57861-57873 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T185 58543-58559 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T186 58564-58583 Phenotype denotes recurrent infection http://purl.obolibrary.org/obo/HP_0002719
T187 58646-58670 Phenotype denotes obstructive lung disease http://purl.obolibrary.org/obo/HP_0006536
T188 58779-58804 Phenotype denotes Obstructive Lung Diseases http://purl.obolibrary.org/obo/HP_0006536
T189 58913-58938 Phenotype denotes obstructive lung diseases http://purl.obolibrary.org/obo/HP_0006536
T190 58963-58983 Phenotype denotes recurrent infections http://purl.obolibrary.org/obo/HP_0002719
T191 59233-59258 Phenotype denotes obstructive lung diseases http://purl.obolibrary.org/obo/HP_0006536
T192 59422-59443 Phenotype denotes chronic lung diseases http://purl.obolibrary.org/obo/HP_0006528
T193 59466-59482 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T194 60178-60194 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T195 60265-60269 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T196 60270-60279 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T197 61122-61126 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T198 61127-61136 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T199 61282-61306 Phenotype denotes obstructive lung disease http://purl.obolibrary.org/obo/HP_0006536
T200 61506-61510 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T201 61511-61520 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T202 61765-61769 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T203 61770-61779 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T204 62627-62643 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T205 63200-63204 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T206 63205-63214 Phenotype denotes emphysema http://purl.obolibrary.org/obo/HP_0002097
T207 63341-63353 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T208 63369-63388 Phenotype denotes pulmonary infection http://purl.obolibrary.org/obo/HP_0006532
T209 64896-64900 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T210 65000-65020 Phenotype denotes pulmonary infections http://purl.obolibrary.org/obo/HP_0006532
T211 65024-65028 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T212 65725-65749 Phenotype denotes obstructive lung disease http://purl.obolibrary.org/obo/HP_0006536
T213 65996-66000 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T214 74127-74155 Phenotype denotes severity of viral infections http://purl.obolibrary.org/obo/HP_0031691
T215 74594-74600 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T216 74615-74619 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T217 75795-75816 Phenotype denotes respiratory infection http://purl.obolibrary.org/obo/HP_0011947
T218 76189-76201 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T219 79973-79985 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T220 80084-80109 Phenotype denotes obstructive lung diseases http://purl.obolibrary.org/obo/HP_0006536
T221 80393-80405 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T222 80676-80713 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T223 80715-80719 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T224 81505-81525 Phenotype denotes chronic lung disease http://purl.obolibrary.org/obo/HP_0006528
T225 81944-81956 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T226 82042-82058 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T227 82842-82846 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T228 82858-82878 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T229 82907-82925 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 0-9 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T2 0-9 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T3 36-51 http://purl.obolibrary.org/obo/GO_0006955 denotes Immune Response
T4 146-166 http://purl.obolibrary.org/obo/GO_0019725 denotes cellular homeostasis
T5 155-166 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T6 180-189 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T7 323-343 http://purl.obolibrary.org/obo/GO_0019725 denotes cellular homeostasis
T8 332-343 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T9 426-435 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T10 426-435 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T11 547-559 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T12 835-844 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T13 835-844 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T14 1065-1074 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T15 1065-1074 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T16 1079-1098 http://purl.obolibrary.org/obo/GO_0090398 denotes cellular senescence
T17 1119-1131 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T18 1265-1280 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T19 1498-1549 http://purl.obolibrary.org/obo/GO_0005260 denotes cystic fibrosis transmembrane conductance regulator
T20 1551-1555 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T21 1557-1572 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T22 1684-1693 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T23 1684-1693 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T24 1738-1750 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T25 2725-2740 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T26 2896-2905 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T27 2896-2905 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T28 3196-3205 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T29 3196-3205 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T30 3233-3253 http://purl.obolibrary.org/obo/GO_0044248 denotes cellular degradation
T31 3242-3253 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T32 3449-3458 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T33 3449-3458 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T34 3468-3477 http://purl.obolibrary.org/obo/GO_0098792 denotes xenophagy
T35 3579-3588 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T36 3579-3588 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T37 3597-3611 http://purl.obolibrary.org/obo/GO_0016236 denotes macroautophagy
T38 3985-3996 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T39 4121-4131 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T40 4195-4216 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostatic processes
T41 4235-4244 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T42 4235-4244 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T43 4277-4288 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T44 4513-4533 http://purl.obolibrary.org/obo/GO_0019725 denotes cellular homeostasis
T45 4522-4533 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T46 4861-4872 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T47 4873-4888 http://purl.obolibrary.org/obo/GO_0036503 denotes (ERAD) pathways
T48 4874-4878 http://purl.obolibrary.org/obo/GO_0030433 denotes ERAD
T49 4904-4908 http://purl.obolibrary.org/obo/GO_0030433 denotes ERAD
T50 4957-5008 http://purl.obolibrary.org/obo/GO_0005260 denotes cystic fibrosis transmembrane conductance regulator
T51 5010-5014 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T52 5072-5084 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T53 5179-5200 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T54 5225-5237 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T55 5655-5660 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T56 5783-5792 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T57 5783-5792 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T58 5969-5978 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T59 5969-5978 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T60 6021-6033 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T61 6325-6337 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T62 6355-6364 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T63 6355-6364 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T64 6662-6667 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T65 6788-6793 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T66 6914-6923 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T67 6914-6923 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T68 7237-7246 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T69 7237-7246 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T70 7302-7314 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T71 7343-7352 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T72 7343-7352 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T73 7445-7454 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T74 7445-7454 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T75 7564-7573 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T76 7564-7573 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T77 7653-7662 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T78 7653-7662 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T79 7690-7699 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T80 7690-7699 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T81 7912-7921 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T82 7912-7921 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T83 7981-7990 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T84 7981-7990 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T85 8063-8072 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T86 8063-8072 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T87 8096-8112 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T88 8149-8158 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T89 8149-8158 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T90 8173-8182 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T91 8173-8182 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T92 8440-8449 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T93 8440-8449 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T94 8607-8616 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T95 8607-8616 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T96 8693-8705 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T97 8797-8806 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T98 8797-8806 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T99 8848-8860 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T100 8958-8962 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T101 9039-9043 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T102 9081-9085 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T103 9219-9231 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T104 9370-9374 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T105 9546-9555 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T106 9624-9628 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T107 9643-9651 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T108 9643-9651 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T109 9643-9651 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T110 9643-9651 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T111 9735-9739 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T112 9837-9858 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T113 9863-9875 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T114 9947-9951 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T115 10009-10034 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T116 10076-10091 http://purl.obolibrary.org/obo/GO_0006811 denotes ion transporter
T117 10161-10165 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T118 10194-10212 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T119 10194-10203 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T120 10221-10234 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T121 10409-10413 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T122 10598-10602 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T123 10729-10748 http://purl.obolibrary.org/obo/GO_0030168 denotes platelet activation
T124 10798-10810 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T125 10856-10865 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T126 10856-10865 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T127 10981-10985 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T128 10995-11004 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T129 10995-11004 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T130 11034-11038 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T131 11213-11222 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T132 11213-11222 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T133 11286-11290 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T134 11331-11335 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T135 11492-11496 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T136 11561-11570 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T137 11561-11570 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T138 11572-11591 http://purl.obolibrary.org/obo/GO_0090398 denotes cellular senescence
T139 11603-11612 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T140 11603-11612 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T141 11627-11648 http://purl.obolibrary.org/obo/GO_0120197 denotes mucociliary clearance
T142 11724-11733 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T143 11724-11733 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T144 11785-11789 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T145 11920-11930 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T146 12025-12034 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T147 12025-12034 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T148 12165-12174 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T149 12165-12174 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T150 12264-12273 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T151 12264-12273 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T152 12322-12334 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T153 12383-12392 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T154 12383-12392 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T155 12429-12438 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T156 12429-12438 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T157 12495-12515 http://purl.obolibrary.org/obo/GO_0019725 denotes cellular homeostasis
T158 12504-12515 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T159 12664-12673 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T160 12664-12673 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T161 12786-12795 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T162 12786-12795 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T163 12838-12847 http://purl.obolibrary.org/obo/GO_0098792 denotes xenophagy
T164 12875-12900 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T165 12960-12969 http://purl.obolibrary.org/obo/GO_0000423 denotes mitophagy
T166 12960-12969 http://purl.obolibrary.org/obo/GO_0000422 denotes mitophagy
T167 13034-13043 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T168 13034-13043 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T169 13257-13266 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T170 13257-13266 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T171 13283-13295 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T172 13369-13378 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T173 13369-13378 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T174 13407-13422 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T175 13558-13573 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T176 13760-13769 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T177 13760-13769 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T178 13865-13874 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T179 13865-13874 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T180 13912-13935 http://purl.obolibrary.org/obo/GO_0001845 denotes phagolysosome formation
T181 13926-13935 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T182 14172-14181 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T183 14172-14181 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T184 14212-14227 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T185 14288-14297 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T186 14288-14297 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T187 14385-14397 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T188 14438-14447 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T189 14438-14447 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T190 14478-14493 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T191 14554-14563 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T192 14554-14563 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T193 14685-14696 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T194 14774-14783 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T195 14774-14783 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T196 14927-14939 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T197 15002-15011 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T198 15002-15011 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T199 15015-15030 http://purl.obolibrary.org/obo/GO_0032496 denotes response to LPS
T200 15075-15084 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T201 15075-15084 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T202 15113-15128 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T203 15363-15372 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T204 15363-15372 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T205 15458-15467 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T206 15458-15467 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T207 15575-15590 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T208 15683-15692 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T209 15683-15692 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T210 15721-15736 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T211 15837-15846 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T212 15837-15846 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T213 15885-15894 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T214 15885-15894 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T215 16042-16051 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T216 16042-16051 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T217 16130-16135 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T218 16222-16242 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T219 16222-16235 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T220 16263-16272 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T221 16263-16272 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T222 16387-16399 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T223 16441-16450 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T224 16441-16450 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T225 16473-16482 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T226 16473-16482 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T227 16677-16686 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T228 16677-16686 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T229 16738-16747 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T230 16738-16747 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T231 16801-16810 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T232 16801-16810 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T233 16894-16903 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T234 16894-16903 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T235 17024-17033 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T236 17024-17033 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T237 17264-17273 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T238 17264-17273 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T239 17344-17349 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T240 17376-17385 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T241 17376-17385 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T242 17457-17466 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T243 17457-17466 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T244 17536-17545 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T245 17536-17545 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T246 17608-17617 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T247 17608-17617 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T248 17771-17780 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T249 17799-17808 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T250 17799-17808 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T251 17904-17913 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T252 17904-17913 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T253 17977-17992 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T254 18128-18137 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T255 18237-18246 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T256 18237-18246 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T257 18463-18472 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T258 18463-18472 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T259 18746-18755 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T260 18923-18932 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T261 18923-18932 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T262 19137-19160 http://purl.obolibrary.org/obo/GO_0001845 denotes phagolysosome formation
T263 19151-19160 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T264 19293-19302 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T265 19293-19302 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T266 19430-19439 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T267 19430-19439 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T268 19494-19498 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T269 19527-19536 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T270 19527-19536 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T271 19584-19588 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T272 19706-19710 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T273 19763-19767 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T274 19908-19912 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T275 19922-19931 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T276 19922-19931 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T277 20083-20087 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T278 20135-20139 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T279 20182-20191 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T280 20182-20191 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T281 20193-20197 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T282 20299-20303 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T283 20345-20349 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T284 20382-20391 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T285 20382-20391 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T286 20471-20482 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T287 20560-20564 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T288 20610-20619 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T289 20610-20619 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T290 20724-20728 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T291 20759-20768 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T292 20759-20768 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T293 20796-20805 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T294 20796-20805 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T295 20885-20894 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T296 20885-20894 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T297 20984-20993 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T298 20984-20993 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T299 20995-21014 http://purl.obolibrary.org/obo/GO_0090398 denotes cellular senescence
T300 21073-21085 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T301 21495-21507 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T302 21783-21792 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T303 21783-21792 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T304 21902-21911 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T305 21902-21911 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T306 21943-21952 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T307 21943-21952 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T308 22111-22120 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T309 22111-22120 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T310 22167-22176 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T311 22167-22176 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T312 22372-22381 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T313 22372-22381 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T314 22543-22552 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T315 22543-22552 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T316 22621-22633 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T317 22909-22918 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T318 22909-22918 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T319 23070-23079 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T320 23070-23079 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T321 23190-23199 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T322 23276-23285 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T323 23276-23285 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T324 23390-23399 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T325 23390-23399 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T326 23454-23463 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T327 23454-23463 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T328 23605-23614 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T329 23605-23614 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T330 23864-23873 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T331 23864-23873 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T332 23938-23947 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T333 23938-23947 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T334 24067-24076 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T335 24067-24076 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T336 24178-24187 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T337 24178-24187 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T338 24279-24303 http://purl.obolibrary.org/obo/GO_0097352 denotes autophagosome maturation
T339 24461-24470 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T340 24461-24470 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T341 24603-24612 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T342 24603-24612 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T343 24627-24636 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T344 24627-24636 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T345 24778-24787 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T346 24778-24787 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T347 25069-25078 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T348 25069-25078 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T349 25294-25303 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T350 25294-25303 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T351 25514-25533 http://purl.obolibrary.org/obo/GO_0043066 denotes inhibited apoptosis
T352 25524-25533 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T353 25524-25533 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T354 25546-25555 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T355 25546-25555 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T356 25584-25603 http://purl.obolibrary.org/obo/GO_0032496 denotes response to the LPS
T357 25654-25663 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T358 25798-25807 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T359 25798-25807 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T360 26084-26093 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T361 26084-26093 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T362 26274-26283 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T363 26274-26283 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T364 26583-26592 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T365 26583-26592 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T366 26695-26704 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T367 26695-26704 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T368 26797-26806 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T369 26797-26806 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T370 26901-26910 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T371 26901-26910 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T372 27113-27122 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T373 27113-27122 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T374 27244-27260 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T375 27565-27574 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T376 27565-27574 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T377 27927-27936 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T378 27927-27936 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T379 27995-28006 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T380 28193-28202 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T381 28207-28216 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T382 28207-28216 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T383 28248-28257 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T384 28248-28257 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T385 28360-28369 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T386 28360-28369 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T387 28457-28472 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T388 28571-28580 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T389 28571-28580 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T390 28654-28670 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T391 28748-28757 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T392 28748-28757 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T393 28940-28949 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T394 28940-28949 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T395 29049-29058 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T396 29049-29058 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T397 29329-29338 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T398 29329-29338 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T399 29512-29521 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T400 29512-29521 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T401 29594-29609 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T402 29729-29748 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostatic process
T403 29749-29758 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T404 29749-29758 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T405 30130-30139 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T406 30130-30139 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T407 30212-30224 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T408 30317-30326 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T409 30317-30326 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T410 30386-30395 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T411 30386-30395 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T412 30659-30668 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T413 30659-30668 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T414 30747-30756 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T415 30747-30756 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T416 30850-30872 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T417 30892-30904 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T418 31178-31199 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T419 31414-31423 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T420 31414-31423 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T421 31431-31452 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T422 31520-31529 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T423 31520-31529 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T424 31580-31592 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T425 31627-31636 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T426 31627-31636 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T427 31660-31681 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T428 31846-31855 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T429 31846-31855 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T430 31901-31910 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T431 31901-31910 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T432 32165-32174 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T433 32165-32174 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T434 32259-32268 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T435 32259-32268 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T436 32542-32551 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T437 32542-32551 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T438 32667-32676 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T439 32667-32676 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T440 32770-32779 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T441 32912-32921 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T442 32912-32921 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T443 33197-33202 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T444 33294-33299 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T445 33306-33311 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T446 33450-33459 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T447 33450-33459 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T448 33620-33629 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T449 33620-33629 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T450 33645-33654 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T451 33860-33880 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T452 33860-33873 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T453 33908-33917 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T454 33908-33917 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T455 33959-33968 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T456 33959-33968 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T457 34114-34123 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T458 34114-34123 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T459 34274-34283 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T460 34274-34283 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T461 34326-34345 http://purl.obolibrary.org/obo/GO_0090398 denotes cellular senescence
T462 34514-34523 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T463 34514-34523 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T464 34602-34611 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T465 34602-34611 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T466 34672-34684 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T467 35030-35054 http://purl.obolibrary.org/obo/GO_0097352 denotes autophagosome maturation
T468 35194-35203 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T469 35194-35203 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T470 35233-35242 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T471 35233-35242 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T472 35446-35455 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T473 35446-35455 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T474 35587-35596 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T475 35587-35596 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T476 35913-35922 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T477 35913-35922 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T478 36073-36082 http://purl.obolibrary.org/obo/GO_0000423 denotes mitophagy
T479 36073-36082 http://purl.obolibrary.org/obo/GO_0000422 denotes mitophagy
T480 36135-36147 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T481 36222-36231 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T482 36222-36231 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T483 36395-36404 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T484 36395-36404 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T485 36721-36725 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T486 36769-36781 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T487 36800-36809 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T488 36800-36809 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T489 36880-36884 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T490 37000-37004 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T491 37049-37058 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T492 37049-37058 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T493 37126-37135 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T494 37126-37135 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T495 37153-37165 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T496 37255-37264 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T497 37255-37264 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T498 37757-37772 http://purl.obolibrary.org/obo/GO_0006306 denotes DNA methylation
T499 37761-37772 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T500 37974-37983 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T501 37974-37983 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T502 38135-38166 http://purl.obolibrary.org/obo/GO_0010507 denotes negative regulator of autophagy
T503 38157-38166 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T504 38157-38166 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T505 38310-38319 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T506 38310-38319 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T507 38320-38335 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T508 38430-38439 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T509 38430-38439 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T510 38507-38519 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T511 38543-38552 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T512 38543-38552 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T513 38644-38649 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T514 38668-38677 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T515 38668-38677 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T516 38764-38776 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T517 38853-38862 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T518 38853-38862 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T519 38938-38967 http://purl.obolibrary.org/obo/GO_0036446 denotes myofibroblast differentiation
T520 39100-39109 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T521 39100-39109 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T522 39315-39334 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T523 39741-39750 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T524 39741-39750 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T525 40094-40103 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T526 40094-40103 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T527 40145-40169 http://purl.obolibrary.org/obo/GO_0048144 denotes fibroblast proliferation
T528 40208-40220 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T529 40364-40373 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T530 40364-40373 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T531 40447-40456 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T532 40447-40456 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T533 40538-40547 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T534 40538-40547 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T535 40848-40857 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T536 40848-40857 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T537 40898-40910 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T538 40969-40978 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T539 40969-40978 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T540 41044-41053 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T541 41044-41053 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T542 41162-41171 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T543 41162-41171 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T544 41198-41208 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T545 41265-41274 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T546 41265-41274 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T547 41331-41343 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T548 41376-41388 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T549 41390-41399 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T550 41390-41399 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T551 41640-41649 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T552 41640-41649 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T553 41684-41693 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T554 41684-41693 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T555 41703-41707 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T556 41712-41727 http://purl.obolibrary.org/obo/GO_0006955 denotes Immune Response
T557 41760-41764 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T558 41862-41871 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T559 41862-41871 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T560 41905-41909 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T561 41992-42001 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T562 41992-42001 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T563 42020-42024 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T564 42057-42061 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T565 42071-42080 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T566 42071-42080 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T567 42197-42206 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T568 42197-42206 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T569 42240-42244 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T570 42331-42343 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T571 42385-42389 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T572 42449-42453 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T573 42525-42534 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T574 42525-42534 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T575 42681-42685 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T576 42690-42699 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T577 42690-42699 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T578 42948-42957 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T579 42980-42989 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T580 42980-42989 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T581 43046-43050 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T582 43108-43117 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T583 43108-43117 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T584 43127-43138 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T585 43190-43199 http://purl.obolibrary.org/obo/GO_0098792 denotes xenophagy
T586 43287-43299 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T587 43356-43370 http://purl.obolibrary.org/obo/GO_0016236 denotes macroautophagy
T588 43404-43413 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T589 43660-43671 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T590 43685-43694 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T591 43685-43694 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T592 43786-43812 http://purl.obolibrary.org/obo/GO_0008306 denotes conditions and in response
T593 43837-43846 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T594 43837-43846 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T595 43883-43896 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T596 43923-43932 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T597 44456-44465 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T598 44456-44465 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T599 44536-44545 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T600 44536-44545 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T601 44660-44670 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T602 44688-44697 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T603 44688-44697 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T604 44742-44754 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T605 44826-44835 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T606 44826-44835 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T607 44871-44884 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T608 44991-45000 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T609 44991-45000 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T610 45216-45251 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen processing and presentation
T611 45362-45382 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen presentation
T612 45429-45438 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T613 45429-45438 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T614 45506-45521 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T615 45577-45586 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T616 45577-45586 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T617 45605-45625 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen presentation
T618 45697-45721 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune response
T619 45706-45721 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T620 45778-45787 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T621 45778-45787 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T622 45832-45836 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T623 46054-46058 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T624 46175-46179 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T625 46281-46296 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T626 46807-46825 http://purl.obolibrary.org/obo/GO_0006821 denotes chloride transport
T627 46816-46825 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T628 46867-46871 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T629 47166-47178 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T630 47399-47403 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T631 47434-47438 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T632 47481-47502 http://purl.obolibrary.org/obo/GO_0042119 denotes neutrophil activation
T633 47556-47560 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T634 47694-47704 http://purl.obolibrary.org/obo/GO_0006887 denotes exocytosis
T635 47781-47785 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T636 47806-47810 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T637 47846-47867 http://purl.obolibrary.org/obo/GO_0042119 denotes neutrophil activation
T638 47957-47966 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T639 47957-47966 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T640 47971-47975 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T641 48019-48049 http://purl.obolibrary.org/obo/GO_0050776 denotes regulating the immune response
T642 48034-48049 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T643 48101-48105 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T644 48129-48138 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T645 48129-48138 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T646 48201-48213 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T647 48230-48239 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T648 48230-48239 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T649 48240-48244 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T650 48644-48660 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T651 49031-49040 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T652 49031-49040 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T653 49106-49118 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T654 49372-49376 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T655 49443-49452 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T656 49443-49452 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T657 49550-49559 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T658 49550-49559 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T659 49582-49591 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T660 49582-49591 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T661 49722-49726 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T662 49809-49813 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T663 49878-49887 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T664 49878-49887 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T665 49945-49956 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T666 49982-49986 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T667 50069-50073 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T668 50168-50177 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T669 50168-50177 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T670 50277-50281 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T671 50282-50291 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T672 50282-50291 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T673 50642-50646 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T674 50764-50773 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T675 50764-50773 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T676 50799-50803 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T677 50885-50897 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T678 50945-50949 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T679 50960-50969 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T680 50960-50969 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T681 51062-51074 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T682 51138-51154 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T683 51156-51160 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T684 51161-51170 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T685 51161-51170 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T686 51257-51261 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T687 51456-51460 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T688 51577-51581 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T689 51582-51593 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy’s
T690 51582-51593 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy’s
T691 51702-51711 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T692 51702-51711 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T693 51725-51729 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T694 51819-51823 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T695 51834-51843 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T696 51834-51843 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T697 51956-51960 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T698 51961-51970 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T699 51961-51970 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T700 52133-52137 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T701 52138-52147 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T702 52138-52147 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T703 52299-52303 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T704 52364-52368 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T705 52508-52517 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T706 52508-52517 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T707 52538-52542 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T708 52543-52552 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T709 52543-52552 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T710 52660-52680 http://purl.obolibrary.org/obo/GO_0019725 denotes cellular homeostasis
T711 52669-52680 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T712 52725-52737 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T713 52859-52863 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T714 52864-52873 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T715 52864-52873 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T716 53051-53055 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T717 53077-53086 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T718 53077-53086 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T719 53119-53134 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T720 53165-53182 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T721 53165-53182 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T722 53205-53209 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T723 53214-53223 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T724 53214-53223 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T725 53413-53417 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T726 53419-53428 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T727 53419-53428 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T728 53445-53457 http://purl.obolibrary.org/obo/GO_0009405 denotes Pathogenesis
T729 53511-53520 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T730 53511-53520 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T731 53793-53798 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T732 53874-53878 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T733 54001-54010 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T734 54001-54010 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T735 54123-54142 http://purl.obolibrary.org/obo/GO_0090398 denotes cellular senescence
T736 54148-54157 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T737 54148-54157 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T738 54397-54417 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T739 54397-54410 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T740 54440-54449 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T741 54440-54449 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T742 54510-54519 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T743 54738-54747 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T744 54738-54747 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T745 54759-54779 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T746 54759-54772 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T747 54804-54813 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T748 54804-54813 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T749 55107-55119 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T750 55195-55204 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T751 55195-55204 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T752 55368-55372 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T753 55514-55526 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T754 55582-55586 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T755 55725-55746 http://purl.obolibrary.org/obo/GO_0120197 denotes mucociliary clearance
T756 56094-56098 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T757 56150-56154 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T758 56274-56278 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T759 56380-56384 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T760 56405-56417 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T761 56492-56496 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T762 56569-56578 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T763 56569-56578 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T764 56610-56622 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T765 56833-56837 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T766 57009-57013 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T767 57040-57049 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T768 57040-57049 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T769 57071-57080 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T770 57071-57080 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T771 57209-57218 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T772 57209-57218 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T773 57254-57258 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T774 57295-57304 http://purl.obolibrary.org/obo/GO_0061724 denotes lipophagy
T775 57347-57359 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T776 57390-57399 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T777 57390-57399 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T778 57404-57408 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T779 57571-57580 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T780 57571-57580 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T781 57630-57639 http://purl.obolibrary.org/obo/GO_0061724 denotes lipophagy
T782 57711-57715 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T783 57899-57911 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T784 57913-57922 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T785 57913-57922 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T786 58335-58347 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T787 58424-58428 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T788 58429-58438 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T789 58429-58438 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T790 58671-58683 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T791 58689-58698 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T792 58689-58698 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T793 58739-58751 http://purl.obolibrary.org/obo/GO_0009405 denotes Pathogenesis
T794 58825-58834 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T795 58825-58834 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T796 58835-58839 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T797 58889-58901 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T798 59145-59154 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T799 59145-59154 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T800 59155-59159 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T801 59259-59271 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T802 59358-59367 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T803 59358-59367 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T804 59484-59493 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T805 59484-59493 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T806 59495-59514 http://purl.obolibrary.org/obo/GO_0090398 denotes cellular senescence
T807 59553-59569 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T808 59674-59683 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T809 59674-59683 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T810 59684-59688 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T811 60039-60048 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T812 60039-60048 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T813 60072-60095 http://purl.obolibrary.org/obo/GO_0000045 denotes autophagosome formation
T814 60086-60095 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T815 60151-60156 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T816 60196-60205 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T817 60196-60205 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T818 60207-60226 http://purl.obolibrary.org/obo/GO_0090398 denotes cellular senescence
T819 60427-60431 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T820 60489-60493 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T821 61447-61451 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T822 61472-61481 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T823 61472-61481 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T824 61521-61533 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T825 61641-61650 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T826 61641-61650 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T827 61711-61715 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T828 61899-61908 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T829 61910-61914 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T830 61925-61937 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T831 61973-61982 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T832 61973-61982 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T833 62262-62266 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T834 62267-62276 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T835 62267-62276 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T836 62369-62378 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T837 62369-62378 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T838 62445-62454 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T839 62495-62504 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T840 62495-62504 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T841 62592-62601 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T842 62592-62601 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T843 62645-62654 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T844 62645-62654 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T845 62807-62816 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T846 62807-62816 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T847 62871-62883 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T848 62961-62970 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T849 62961-62970 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T850 63035-63047 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T851 63128-63137 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T852 63128-63137 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T853 63254-63263 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T854 63254-63263 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T855 63825-63829 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T856 63918-63927 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T857 63918-63927 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T858 63990-63994 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T859 64125-64134 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T860 64125-64134 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T861 64224-64233 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T862 64224-64233 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T863 64464-64468 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T864 64520-64524 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T865 64756-64765 http://purl.obolibrary.org/obo/GO_0061724 denotes lipophagy
T866 65050-65059 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T867 65050-65059 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T868 65166-65175 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T869 65166-65175 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T870 65245-65257 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T871 65309-65318 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T872 65309-65318 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T873 65333-65345 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T874 65349-65384 http://purl.obolibrary.org/obo/GO_2000269 denotes regulating the fibroblast apoptosis
T875 65364-65384 http://purl.obolibrary.org/obo/GO_0044346 denotes fibroblast apoptosis
T876 65375-65384 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T877 65375-65384 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T878 65527-65539 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T879 65613-65622 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T880 65613-65622 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T881 65641-65650 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T882 65641-65650 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T883 65750-65762 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T884 66699-66708 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T885 66699-66708 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T886 66744-66748 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T887 66749-66758 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T888 66749-66758 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T889 66946-66950 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T890 66951-66960 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T891 66951-66960 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T892 67070-67079 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T893 67070-67079 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T894 67308-67317 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T895 67308-67317 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T896 67510-67514 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T897 67543-67547 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T898 67737-67746 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T899 67737-67746 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T900 67809-67813 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T901 67818-67827 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T902 67818-67827 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T903 68072-68087 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T904 68323-68327 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T905 68479-68483 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T906 68528-68537 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T907 68528-68537 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T908 68575-68579 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T909 68619-68623 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T910 68624-68633 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T911 68624-68633 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T912 69192-69196 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T913 69370-69379 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T914 69370-69379 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T915 69536-69545 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T916 69536-69545 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T917 69746-69755 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T918 69746-69755 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T919 69811-69815 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T920 69816-69825 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T921 69816-69825 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T922 69869-69878 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T923 69869-69878 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T924 69919-69923 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T925 69924-69933 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T926 69924-69933 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T927 70237-70241 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T928 70242-70251 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T929 70242-70251 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T930 71366-71375 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T931 71366-71375 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T932 71837-71846 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T933 71837-71846 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T934 71939-71943 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T935 72137-72141 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T936 72142-72151 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T937 72142-72151 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T938 72226-72235 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T939 72226-72235 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T940 72269-72292 http://purl.obolibrary.org/obo/GO_0000045 denotes autophagosome formation
T941 72283-72292 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T942 72772-72776 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T943 72777-72786 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T944 72777-72786 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T945 72846-72850 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T946 72851-72860 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T947 72851-72860 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T948 73270-73279 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T949 73270-73279 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T950 73356-73371 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T951 74044-74053 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T952 74044-74053 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T953 74139-74155 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T954 74187-74203 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T955 74270-74279 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T956 74270-74279 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T957 74830-74839 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T958 74830-74839 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T959 74853-74862 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T960 74853-74862 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T961 75121-75130 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T962 75121-75130 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T963 75247-75256 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T964 75247-75256 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T965 75311-75320 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T966 75311-75320 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T967 75484-75493 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T968 75484-75493 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T969 75501-75516 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T970 75658-75667 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T971 75658-75667 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T972 75950-75971 http://purl.obolibrary.org/obo/GO_0009615 denotes response to the virus
T973 76647-76656 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T974 76647-76656 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T975 76800-76811 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T976 76914-76923 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T977 76914-76923 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T978 77149-77158 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T979 77149-77158 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T980 77276-77285 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T981 77276-77285 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T982 77330-77339 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T983 77330-77339 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T984 77698-77707 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T985 77698-77707 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T986 77764-77773 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T987 77764-77773 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T988 77825-77829 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T989 77830-77839 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T990 77830-77839 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T991 78037-78046 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T992 78037-78046 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T993 78196-78205 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T994 78196-78205 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T995 78282-78298 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T996 78376-78385 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T997 78376-78385 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T998 78460-78471 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T999 78496-78505 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T1000 78496-78505 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T1001 78665-78674 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T1002 78665-78674 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T1003 78968-78977 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T1004 78968-78977 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T1005 79340-79346 http://purl.obolibrary.org/obo/GO_0060361 denotes Flight
T1006 79935-79939 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T1007 79940-79958 http://purl.obolibrary.org/obo/GO_0016485 denotes protein-processing
T1008 80204-80215 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T1009 80406-80418 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T1010 80462-80513 http://purl.obolibrary.org/obo/GO_0005260 denotes cystic fibrosis transmembrane conductance regulator
T1011 80515-80519 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T1012 80564-80579 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T1013 80670-80674 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T1014 80733-80737 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T1015 80745-80749 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T1016 81010-81014 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T1017 81229-81238 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T1018 81279-81288 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T1019 81378-81389 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T1020 81408-81423 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T1021 81460-81473 http://purl.obolibrary.org/obo/GO_1903409 denotes ROS formation
T1022 81464-81473 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T1023 81582-81598 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T1024 81839-81848 http://purl.obolibrary.org/obo/GO_0098792 denotes xenophagy
T1025 81903-81915 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T1026 81921-81933 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T1027 81968-81977 http://purl.obolibrary.org/obo/GO_0016236 denotes Autophagy
T1028 81968-81977 http://purl.obolibrary.org/obo/GO_0006914 denotes Autophagy
T1029 82141-82150 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T1030 82141-82150 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T1031 82320-82329 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T1032 82320-82329 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T1033 82354-82358 http://purl.obolibrary.org/obo/GO_0005260 denotes CFTR
T1034 82764-82780 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 57135-57151 GlycoEpitope denotes lactosylceramide http://www.glycoepitope.jp/epitopes/EP0078

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-115 Sentence denotes Autophagy Augmentation to Alleviate Immune Response Dysfunction, and Resolve Respiratory and COVID-19 Exacerbations
T2 117-125 Sentence denotes Abstract
T3 126-317 Sentence denotes The preservation of cellular homeostasis requires the synthesis of new proteins (proteostasis) and organelles, and the effective removal of misfolded or impaired proteins and cellular debris.
T4 318-453 Sentence denotes This cellular homeostasis involves two key proteostasis mechanisms, the ubiquitin proteasome system and the autophagy–lysosome pathway.
T5 454-808 Sentence denotes These catabolic pathways have been known to be involved in respiratory exacerbations and the pathogenesis of various lung diseases, such as chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), idiopathic pulmonary fibrosis (IPF), acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and coronavirus disease-2019 (COVID-19).
T6 809-1165 Sentence denotes Briefly, proteostasis and autophagy processes are known to decline over time with age, cigarette or biomass smoke exposure, and/or influenced by underlying genetic factors, resulting in the accumulation of misfolded proteins and cellular debris, elevating apoptosis and cellular senescence, and initiating the pathogenesis of acute or chronic lung disease.
T7 1166-1448 Sentence denotes Moreover, autophagic dysfunction results in an impaired microbial clearance, post-bacterial and/or viral infection(s) which contribute to the initiation of acute and recurrent respiratory exacerbations as well as the progression of chronic obstructive and restrictive lung diseases.
T8 1449-1621 Sentence denotes In addition, the autophagic dysfunction-mediated cystic fibrosis transmembrane conductance regulator (CFTR) immune response impairment further exacerbates the lung disease.
T9 1622-1884 Sentence denotes Recent studies demonstrate the therapeutic potential of novel autophagy augmentation strategies, in alleviating the pathogenesis of chronic obstructive or restrictive lung diseases and exacerbations such as those commonly seen in COPD, CF, ALI/ARDS and COVID-19.
T10 1886-1888 Sentence denotes 1.
T11 1889-1901 Sentence denotes Introduction
T12 1902-2201 Sentence denotes Chronic obstructive and restrictive lung diseases are among the leading causes of mortality worldwide, where acute or recurrent episodes of respiratory exacerbations are not only responsible for significant health care costs and a poor quality of life, but also an increased risk of death [1,2,3,4].
T13 2202-2399 Sentence denotes The airway mucosa is a primary route of entry for pathogenic microorganisms (bacteria, virus and/or fungi) and represents an important barrier in preventing the entry of these infectious organisms.
T14 2400-2839 Sentence denotes In the event that the pathogen evades this mucociliary defense mechanism, the airway epithelial cells utilize complex pathogen clearance mechanisms to restrict the life-threatening exacerbations, where these cells work in collaboration with our immune system, involving both innate and adaptive responses, to launch a robust immune response against the invading pathogens, which if successful, results in pathogen elimination or clearance.
T15 2840-3152 Sentence denotes Thus, providing proof-of-concept evidence in support of autophagy augmentation strategies for alleviating respiratory exacerbations in chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and coronavirus disease-2019 (COVID-19).
T16 3153-3406 Sentence denotes A plethora of studies have identified the “autophagy-lysosome pathway”, a major cellular degradation system, as one of the important mechanisms involved in regulating the immune-mediated pathogen clearance mechanisms in several infection models [5,6,7].
T17 3407-3566 Sentence denotes Evidence suggests that a specific form of autophagy, called “xenophagy”, is responsible for the elimination of bacterial, viral or fungal pathogens [7,8,9,10].
T18 3567-3881 Sentence denotes In general, autophagy (mainly macroautophagy) is one of the two components of the cellular homeostatic machinery called the “proteostasis network (PN)” [11,12,13,14], which could be termed as the “master regulator of cellular well-being”, as it regulates all the processes involved in protein turnover in the cell.
T19 3882-4217 Sentence denotes The other component of the PN is the ubiquitin-proteasome system (UPS), which deals primarily with the degradation of cellular proteins [15,16,17,18,19] which allows protein turnover and a replacement of misfolded proteins, as well as the regulation of vital regulatory proteins involved in a variety of cellular homeostatic processes.
T20 4218-4448 Sentence denotes In contrast, the autophagy-lysosome pathway can handle the degradation of much broader and larger cargo, such as protein aggregates, lipids, damaged organelles, or infectious agents such as bacteria and viruses [9,20,21,22,23,24].
T21 4449-4701 Sentence denotes These two components of the PN play a vital role in maintaining cellular homeostasis by facilitating the removal of these dysfunctional cellular components while maintaining or replenishing the levels of proteins, lipids, etc., via synthetic machinery.
T22 4702-4889 Sentence denotes Other proteostatic mechanisms include the unfolded protein response (UPR), small ubiquitin-like modifier (SUMO), and the endoplasmic reticulum (ER)-associated degradation (ERAD) pathways.
T23 4890-5099 Sentence denotes Both SUMO and ERAD have a role in the trafficking of the misfolded cystic fibrosis transmembrane conductance regulator (CFTR), which is the dysfunctional protein responsible for the pathogenesis of CF [25,26].
T24 5100-5273 Sentence denotes Furthermore, the dysregulation of UPR has been shown to lead to an exaggerated inflammatory response that plays a role in CF pathogenesis progression and exacerbations [27].
T25 5274-5540 Sentence denotes Therefore, it is evident that any dysregulation of the PN components leads to severe life-threatening diseases that includes proteinopathies, neurodegenerative diseases, age-related disorders, and chronic respiratory diseases such as CF and COPD [11,13,15,28,29,30].
T26 5541-5745 Sentence denotes Respiratory infections serve as a trigger for disease exacerbation, while exposure to tobacco, biomass smoke, and aging, are the leading causes for COPD-emphysema development and progression [4,31,32,33].
T27 5746-6073 Sentence denotes We and others have demonstrated that autophagy impairment is the key central mechanism for tobacco, biomass smoke or e-cigarette vapor (eCV) exposure and the age-related induction of inflammatory-oxidative stress, alveolar apoptosis and senescence, leading to COPD-emphysema pathogenesis and progression [33,34,35,36,37,38,39].
T28 6074-6278 Sentence denotes Additionally, the above-described causative mechanisms also hamper the pathogen clearance, and thus make the individual more prone to acute or recurrent respiratory infections or exacerbations [35,39,40].
T29 6279-6538 Sentence denotes Mechanistically, cigarette smoke (CS)-induced phagocytosis defects involves autophagy impairment, which blunts the clearance and promotes the survival of disease-causing pathogens, thereby facilitating chronic infections or recurrent exacerbations [34,35,36].
T30 6539-6778 Sentence denotes In addition, we recently demonstrated that exposure to CS and other noxious environmental agents promotes accelerated lung aging, which is another important factor contributing to increased infections in chronic lung disease subjects [33].
T31 6779-6893 Sentence denotes In fact, aging per se is responsible for an increased risk of pulmonary infections due to the decline of immunity.
T32 6894-7131 Sentence denotes Notably, the PN and autophagy are known to decrease over time with age, and therefore, serve a crucial role in determining the increased risk of lung infections in the elderly, by virtue of hampered pathogen clearance mechanisms [13,41].
T33 7132-7342 Sentence denotes Therefore, several studies, including our recent reports, demonstrate the therapeutic potential of novel autophagy augmentation strategies for controlling COPD-emphysema pathogenesis and progression [22,42,43].
T34 7343-7638 Sentence denotes Autophagy plays a crucial role in the elimination of pathogens, and the pharmacological disruption of autophagy has been shown to impair host defense against Pseudomonas aeruginosa (P. aeruginosa), while the induction of autophagy facilitates P. aeruginosa clearance from murine lungs [5,44,45].
T35 7639-7836 Sentence denotes Additionally, autophagy-related 7 (ATG7)-dependent autophagy is reported to have a significant role in murine host resistance to Klebsiella pneumoniae, an important respiratory track pathogen [46].
T36 7837-8078 Sentence denotes Similarly, during a pulmonary infection with Chlamydia pneumoniae in mice, autophagy restricts inflammasome activation, while mice deficient in autophagy demonstrate an increased mortality, highlighting the protective role of autophagy [47].
T37 8079-8159 Sentence denotes Immunity against viral infections in the airways is also regulated by autophagy.
T38 8160-8308 Sentence denotes For example, autophagy deficiency promotes interleukin (IL)-17-mediated lung pathology in mice infected with respiratory syncytial virus (RSV) [48].
T39 8309-8455 Sentence denotes Furthermore, a recent study demonstrates that IL-22 inhibits RSV production by blocking the virus-mediated suppression of cellular autophagy [49].
T40 8456-8754 Sentence denotes Moreover, recent studies on Middle East respiratory syndrome (MERS) coronavirus [50] provide proof-of-concept evidence on the therapeutic potential of autophagy modulating drugs for combating the SARS-COV2 infection, cytokine storm, and pathogenesis of severe ARDS-like COVID-19 fatal lung disease.
T41 8755-8913 Sentence denotes Another elaborately studied example where autophagy regulates inflammatory-oxidative stress, inflammation, and infection-mediated disease exacerbations is CF.
T42 8914-9298 Sentence denotes CF is a genetic disorder, wherein the ΔF508-CFTR is the most common mutation leading to lack of membrane-resident functional CFTR, where the absence of the functional CFTR on the plasma membrane (PM) deteriorates the pathogen clearance ability in CF subjects, leading to persistent infections and chronic inflammation, culminating into a catastrophic lung function decline [51,52,53].
T43 9299-9570 Sentence denotes Studies in CF cell lines and knockout mice suggest that the absence of CFTR by itself is sufficient to promote a pro-inflammatory milieu, at least in part, by the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) signaling [54,55,56,57].
T44 9571-9745 Sentence denotes Moreover, a transient transfection of wild type (WT)-CFTR reduced tumor necrosis factor α (TNFα)-mediated NFκB activation, confirming the anti-inflammatory role of CFTR [55].
T45 9746-9911 Sentence denotes Furthermore, a P. aeruginosa infection in CF mice leads to a more pronounced NFκB-mediated inflammatory response and pathogenesis of CF-related lung disease [51,58].
T46 9912-10092 Sentence denotes Thus, membrane-resident functional CFTR is demonstrated to be a critical regulator of innate and adaptive immune responses, in addition to its classical role as an ion transporter.
T47 10093-10344 Sentence denotes A recent comprehensive article summarizes the role of dysfunctional CFTR in the controlling cellular signaling pathways used by innate immune cells for combating infections such as airway epithelial cells, neutrophils, monocytes, and macrophages [59].
T48 10345-10560 Sentence denotes Additionally, we and others have shown a clear role of membrane-CFTR in regulating the function of adaptive immune cells, such as CD3+ T cells, CD4+ T cells, CD4+FoxP3+ regulatory T cells (T regs), and B cells [59].
T49 10561-10849 Sentence denotes A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60].
T50 10850-11016 Sentence denotes Thus, autophagy plays a vital role in limiting lung infections, and it is evident that a complete or partial absence of functional CFTR leads to autophagy impairment.
T51 11017-11239 Sentence denotes Mechanistically, CFTR loss or dysfunction results in the reactive oxygen species (ROS)-mediated activation of transglutaminase-2 (TGM-2), and inactivation of the Beclin-1 complex, thereby causing autophagy impairment [61].
T52 11240-11477 Sentence denotes Apart from the genetic loss or dysfunction of CFTR, exposure to CS also leads to decreased CFTR activity and expression in vitro, in animal models and in smokers with or without COPD, primarily via ROS-dependent mechanisms [22,42,62,63].
T53 11478-11672 Sentence denotes This acquired CFTR dysfunction results in increased inflammatory-oxidative stress, apoptosis, cellular senescence, defective autophagy, and impaired mucociliary clearance, all hallmarks of COPD.
T54 11673-11988 Sentence denotes To summarize, we and others have demonstrated that autophagy augmentation has the potential to not only control CFTR dysfunction-mediated pathologies in CF and COPD, but also allows the clearance of opportunistic infections while balancing immune regulation to avoid recurrent exacerbations and disease progression.
T55 11989-12128 Sentence denotes This provides a potential to tailor autophagy augmentation for acute and respiratory exacerbations in CF, COPD, ALI/ARDS and COVID-19, etc.
T56 12129-12378 Sentence denotes Hence, we focus here on the role of autophagy in pulmonary infections and immune dysfunction, where the therapeutic potential of novel autophagy augmenting strategies to alleviate lung disease pathogenesis and respiratory exacerbations is discussed.
T57 12380-12382 Sentence denotes 2.
T58 12383-12428 Sentence denotes Autophagy, Respiratory Infection and Immunity
T59 12429-12602 Sentence denotes Autophagy is the proteostatic process that helps maintain healthy cellular homeostasis by degrading dysfunctional cellular components, lipids, misfolded proteins, etc. [64].
T60 12603-12749 Sentence denotes In addition to processing dysfunctional cellular components, autophagy also plays a critical role in immunity and the clearance of pathogens [64].
T61 12750-12994 Sentence denotes When working at optimal levels, the autophagy pathway can clear cells of infections via xenophagy, participate in innate and adaptive immune responses, activate macrophages, and remove damaged mitochondria via mitophagy [8,9,20,61,64,65,66,67].
T62 12995-13213 Sentence denotes In the respiratory tract specifically, autophagy has even been shown to dictate the length of cilia in the mucociliary escalator that is responsible for the mechanical clearing of pathogens from the airways [68,69,70].
T63 13214-13317 Sentence denotes However, the dysfunction and inhibition of autophagy can lead to the pathogenesis of various illnesses.
T64 13318-13423 Sentence denotes When it comes to respiratory bacterial infections, autophagy is necessary for a complete immune response.
T65 13424-13523 Sentence denotes Mycobacterium tuberculosis (M. tuberculosis) is an intercellular pathogen that causes tuberculosis.
T66 13524-13694 Sentence denotes M. tuberculosis evades the body’s immune response by forming granulomas and blocks phagolysosome trafficking to inhibit the intracellular killing of pathogens [71,72,73].
T67 13695-13982 Sentence denotes Recently, studies have demonstrated the importance of functional autophagy in targeting and killing M. tuberculosis in respiratory cells by showing that the induction of autophagy pathways overcomes the inhibition of phagolysosome formation to effectively kill M. tuberculosis [6,74,75].
T68 13983-14236 Sentence denotes In the case of Streptococcus pneumoniae (S. pneumoniae), which is the most common pathogen causing community acquired pneumonia [76], studies have demonstrated that infection activates the autophagy pathway as part of the body’s immune response [77,78].
T69 14237-14507 Sentence denotes Recently, it has been shown that this induction of autophagy makes the clearance of S. pneumoniae infection more effective by enhancing the rate of phagocytosis by neutrophils [78], demonstrating that autophagy is necessary for an effective immune response in pneumonia.
T70 14508-14734 Sentence denotes Studies have also exhibited the activation of autophagy in alveolar macrophages by Pseudomonas aeruginosa (P. aeruginosa) [5,79] and Klebsiella pneumoniae [46,79] to induce the degradation of these pathogens in phagolysosomes.
T71 14735-14901 Sentence denotes Moreover, there has been evidence that autophagy is activated by lipopolysaccharide (LPS), which is a bacterial toxin on the outer membrane of Gram-negative bacteria.
T72 14902-15074 Sentence denotes Typically, LPS can cause inflammation that leads to lung injury [80,81]; however, the activation of autophagy in response to LPS was shown to attenuate lung injury [82,83].
T73 15075-15300 Sentence denotes Autophagy is not only integral to the immune response to bacterial infections within the respiratory system, but it has been demonstrated to play an important role in the response to viral pathogens as well [8,9,20,65,84,85].
T74 15301-15457 Sentence denotes In the case of the influenza virus, studies have demonstrated autophagy is similarly induced to attenuate the virus and limit its replication [84,85,86,87].
T75 15458-15671 Sentence denotes Autophagy has also been shown to be essential in the activation of dendritic cells to produce cytokines and mount an immune response to respiratory synovial virus (RSV) [88,89], MERS [50] and SARS-CoV2 [90,91,92].
T76 15672-15818 Sentence denotes Therefore, autophagy is an essential part of the immune response against bacterial and viral pathogens attempting to invade the respiratory tract.
T77 15820-15822 Sentence denotes 3.
T78 15823-15858 Sentence denotes Mechanisms of Autophagy Dysfunction
T79 15859-16006 Sentence denotes Despite the importance of autophagy, there are many conditions where this process can become dysfunctional, leading to various pathological states.
T80 16007-16147 Sentence denotes In the lungs, the major sources of autophagy dysfunction includes first- and second-hand cigarette smoke (CS) exposure and aging [35,62,93].
T81 16148-16291 Sentence denotes Studies have demonstrated that CS exposure can decrease the expression of transcription factor-EB (TFEB), a master autophagy regulator [34,35].
T82 16292-16456 Sentence denotes This occurs by the dysfunctional processing of TFEB in response to CS, causing the perinuclear localization of TFEB which prevents the activation of autophagy [62].
T83 16457-16554 Sentence denotes This CS-induced autophagy impairment of TFEB leads to impaired bacterial clearance [22,33,34,35].
T84 16555-16756 Sentence denotes Furthermore, there is evidence that CS exposure increases the accumulation of ubiquitinated proteins and p62 (a marker of autophagy impairment) in aggresome bodies, further impairing autophagy [22,34].
T85 16757-16957 Sentence denotes These deleterious effects of CS exposure on autophagy have also been demonstrated to be present in eCV exposure, which similarly impairs autophagy through the accumulation of aggresome bodies [39,94].
T86 16958-17201 Sentence denotes Furthermore, increasing the severity of pulmonary dysfunction and autophagy impairment has been observed to statistically correlate directly with increased levels of aggresome bodies [36], demonstrating its potential as a prognostic biomarker.
T87 17202-17305 Sentence denotes Hence, CS exposure demonstrates a common, but preventable way autophagy can be impaired in individuals.
T88 17306-17432 Sentence denotes Notably, CS exposure accelerates lung aging, known to be initiated by autophagy decline, which can exacerbate infections [33].
T89 17433-17504 Sentence denotes In addition to smoking, autophagy can be impaired by infectious agents.
T90 17505-17648 Sentence denotes Due to the conserved nature of autophagy, many organisms have adapted and evolved mechanisms to impair autophagy in order to infect their host.
T91 17649-17858 Sentence denotes For example, studies have demonstrated that the influenza virus promotes its own survival by preventing autophagolysosome formation; thus, leading to autophagy impairment via aggresome accumulation [41,85,95].
T92 17859-17998 Sentence denotes Influenza has also been found to prevent the autophagy-dependent presentation of viral antigens necessary to mount an immune response [10].
T93 17999-18263 Sentence denotes Similarly, investigations have found that severe acute respiratory syndrome coronavirus (SARS-CoV) can inhibit autophagolysosome formation with trans membrane papain-like protease 2 (PLP2-TM) to provoke phagolysosome accumulation causing autophagy impairment [96].
T94 18264-18453 Sentence denotes Additionally, the nonstructural protein 6 (NSP6) of coronaviruses has also been observed to restrict autophagosome development to prevent cells from inhibiting coronavirus replication [97].
T95 18454-18540 Sentence denotes However, autophagy inhibition by pathogens is not something that is unique to viruses.
T96 18541-18764 Sentence denotes Legionella pneumophilia (L. pneumophilia) has been found to delay the progression of infected autophagosomes to lysosomes to allow the bacteria to develop an acid-tolerant state prior to autophagolysosome formation [98,99].
T97 18765-18904 Sentence denotes This delay allows L. pneumophilia to replicate in the acidic environment of the autophagolysosome [99] and cause infection within the host.
T98 18905-19087 Sentence denotes This mechanism of autophagy impairment is not unique to L. pneumophilia and has been observed as a common mechanism of bacteria to promote their invasion and replication [7,100,101].
T99 19088-19361 Sentence denotes M. tuberculosis has also been observed to impair phagolysosome formation; meanwhile, other studies have further demonstrated that M. tuberculosis has the ability to activate cellular pathways that inhibit autophagy within macrophages to promote intracellular survival [61].
T100 19362-19475 Sentence denotes Hence, there are various organisms that can infect humans and cause autophagy dysfunction for their own survival.
T101 19476-19556 Sentence denotes The expression of CFTR has been shown to influence autophagy as discussed above.
T102 19557-19725 Sentence denotes One mechanism of decreased CFTR expression is due to the genetic defects found in CF, where the most common mutation seen in these patients is ΔF508-CFTR [102,103,104].
T103 19726-19874 Sentence denotes Studies have demonstrated that ΔF508-CFTR causes protein misfolding that forms aggregates potentially impairing cellular proteostasis [20,42,53,61].
T104 19875-20017 Sentence denotes This dysfunction caused by ΔF508-CFTR includes autophagy dysfunction and decreases pathogen clearance in the airways of patients with CF [53].
T105 20018-20098 Sentence denotes Similar findings were observed in macrophages with dysfunctional CFTR [105,106].
T106 20099-20316 Sentence denotes Along with the genetic mechanism of CFTR dysfunction present in CF that can impair autophagy, CFTR function has been shown to be diminished by CS exposure [40,107,108,109], which is known as acquired CFTR dysfunction.
T107 20317-20512 Sentence denotes One mechanism of CS-induced CFTR dysfunction leading to impaired autophagy is through increased ceramide accumulation as a result of altered sphingolipid homeostasis in COPD patients [22,93,110].
T108 20513-20628 Sentence denotes CS exposure can also increase ROS which causes CFTR to accumulate in aggresome bodies and impair autophagy [42,62].
T109 20629-20791 Sentence denotes Thus, both genetic mechanisms and CS exposure or environmental factors play a critical role in CFTR dysfunction and the resulting autophagy impairment (Figure 1).
T110 20793-20795 Sentence denotes 4.
T111 20796-20841 Sentence denotes Autophagy Dysfunction in Respiratory Diseases
T112 20842-21165 Sentence denotes A number of recent studies have identified autophagy dysfunction as the central mechanism of elevated inflammatory-oxidative stress, alveolar apoptosis, cellular senescence, and recurrent infections, all of which contribute to the pathogenesis and progression of acute and chronic respiratory diseases [22,35,61,62,70,111].
T113 21166-21410 Sentence denotes The inherent ROS in the CS, and the resulting increase in cellular endogenous ROS post-CS exposure, symbiotically contribute to extremely high intracellular ROS levels, which creates an imbalance in the oxidant–antioxidant ratio [22,34,61,112].
T114 21411-21678 Sentence denotes This serves as the basic mechanism for lung cellular injury, tissue damage, and the pathogenesis of chronic obstructive or restrictive lung diseases, such as COPD-emphysema (obstructive) and idiopathic pulmonary fibrosis (IPF, restrictive) [37,38,61,113,114,115,116].
T115 21679-21936 Sentence denotes Several groups including ours have demonstrated that elevated ROS levels are the key upstream driver of autophagy dysfunction, as treatments with antioxidant drugs rescues the age-related, or smoke, or eCV exposure-induced autophagy defect [15,22,42,61,62].
T116 21938-21942 Sentence denotes 4.1.
T117 21943-21987 Sentence denotes Autophagy Defects in Acute Lung Injury (ALI)
T118 21988-22359 Sentence denotes Extensive studies utilizing both in vitro and in vivo models of acute lung injury have demonstrated the protective role of autophagy via regulating inflammatory-oxidative stress, apoptosis, and pathogen clearance mechanisms, even though there were some initial opposing studies [117,118,119], the subsequent detailed evaluation validates the protective role as discussed.
T119 22360-22507 Sentence denotes In general, autophagy is induced upon exposure to common triggers of ALI, such as LPS, bacterial infections, hyperoxia, sepsis, etc. [120,121,122].
T120 22508-22646 Sentence denotes There seems to be a consensus that autophagy indeed plays a protective role in LPS-induced acute lung injury and inflammation [82,83,123].
T121 22647-22975 Sentence denotes In support of this, LPS-mediated severe lung injury in mice, as quantified by lung edema, elevated leukocyte infiltrations, hemorrhages, and increased inflammatory cytokines (IL-1β and TNFα) in the bronchoalveolar lavage fluid (BALF), was further exacerbated by autophagy inhibition, thereby suggesting its protective role [82].
T122 22976-23210 Sentence denotes Mechanistically, the activation of the mammalian target of rapamycin (mTOR) and the resulting autophagy dysfunction has been implicated in promoting LPS-induced lung injury, possibly through the activation of NFκB signaling [124,125].
T123 23211-23453 Sentence denotes Further evidence comes from studies demonstrating the utility of autophagy inducers and/or antioxidant drugs in ameliorating LPS-induced acute lung injuries, while treatment with autophagy inhibitors reversed the beneficial effects [125,126].
T124 23454-23744 Sentence denotes Autophagy is also protective in sepsis-induced lung injury, as a deficiency of proteins interacting with C-kinase 1 (PICK1) in mice leads to defective autophagy, and more severe acute lung injury in the cecal ligation and puncture (CLP) model of sepsis, as compared to WT animals [120,127].
T125 23745-24016 Sentence denotes Additionally, in murine models of hyperoxia-induced ALI, which resembles features of bronchopulmonary dysplasia (BPD), autophagy is proposed as a protective mechanism, and markers of defective autophagy are found in the lungs of human neonates with established BPD [128].
T126 24017-24425 Sentence denotes Another recent study describes the suppression of autophagy as a critical mechanism of chronic parenteral nutrition-mediated lung injury, and treatment with the autophagy inducer, rapamycin (an mTOR inhibitor that initiates nucleation, autophagosome elongation, autophagosome maturation, and autophagosome termination), reversed the lung injury features in the animal model of parenteral nutrition [129,130].
T127 24426-24620 Sentence denotes Finally, mice deficient in crucial autophagy proteins such as Atg7, Atg5 and Atg4a demonstrate more severe ALI features [83,121,130,131], thus confirming the protective role of autophagy in ALI.
T128 24622-24626 Sentence denotes 4.2.
T129 24627-24690 Sentence denotes Autophagy Defects in Acute Respiratory Distress Syndrome (ARDS)
T130 24691-24777 Sentence denotes More severe forms of ALI may progress to acute respiratory distress syndrome, or ARDS.
T131 24778-24867 Sentence denotes Autophagy has been shown to play a critical role in regulating the outcome of ARDS [120].
T132 24868-24974 Sentence denotes The clinical manifestations of ARDS are very severe and may lead to rapid lung function decline and death.
T133 24975-25337 Sentence denotes Using one of most widely used murine models of ALI, the CLP, a recent study demonstrated that autophagy induction by rapamycin was able to improve the survival rate, histological scores, lung wet/dry ratios, PaO2/FiO2, and inflammatory cytokine and myeloperoxidase (MPO) levels in BALF, suggesting a protective role of autophagy in sepsis-induced ALI/ARDS [120].
T134 25338-25481 Sentence denotes In another study, the potential of BML-111, a lipoxin A4 receptor antagonist, was evaluated in controlling LPS-induced septic ALI/ARDS in rats.
T135 25482-25698 Sentence denotes The authors showed that BML-111 inhibited apoptosis and induced autophagy in alveolar macrophages, in response to the LPS challenge, via the suppression of MAPK1 and MAPK8 signaling and was independent of mTOR [132].
T136 25699-25884 Sentence denotes Moreover, BML-111 controlled the LPS-induced production of pro-inflammatory cytokines, and reduced apoptosis in the rat lungs, and thus warrants further investigation in ALI/ARDS [132].
T137 25885-26043 Sentence denotes Mechanical ventilation (MV)-induced lung injury is another severe form of ARDS, wherein the activation of inflammasome has been shown to mediate ALI symptoms.
T138 26044-26267 Sentence denotes In a recent article, starvation-induced autophagy augmentation was shown to protect against LPS- and MV-induced ARDS features by reducing IL-1β levels, decreasing lung permeability, and improving arterial oxygenation [133].
T139 26268-26526 Sentence denotes Thus, autophagy had a protective role in controlling the inflammasome activation and resolution of the MV-induced production of IL-1β, which plays a pathogenic role through inducing hypoxemia and increasing lung permeability in LPS/MV-induced ALI/ARDS [133].
T140 26527-26783 Sentence denotes Although some contrasting reports regarding the role of autophagy in ALI/ARDS were initially reported [134], there has been a consensus on the therapeutic advantage of autophagy augmentation in ALI/ARDS based on significant validation studies [64,120,122].
T141 26784-26877 Sentence denotes Thus, proper autophagy function is essential in attenuating the severity of ARDS in patients.
T142 26879-26883 Sentence denotes 4.3.
T143 26884-26936 Sentence denotes Critical Role of Autophagy in COVID-19 Exacerbations
T144 26937-27073 Sentence denotes The ongoing SARS-CoV-2 pandemic has severely impacted quality of life with a significant health care and socio-economic burden globally.
T145 27074-27272 Sentence denotes In general, the cellular endocytic and autophagy pathways contribute to viral entry and replication, and thus are obvious attractive targets against SARS-CoV-2 and other viral infections [90,91,92].
T146 27273-27511 Sentence denotes The SARS-CoV-2 virus, which causes COVID-19, is highly infectious and can cause cytokine-storm leading to pneumonia and severe lung damage in susceptible subjects by triggering an ARDS-like lung disease, with high-risk of mortality [135].
T147 27512-27709 Sentence denotes Recent evidence suggests that SARS-CoV-2 may inhibit autophagy, which we anticipate as a potential mechanism for severe COVID-19 lung disease due to impaired viral clearance and immune dysfunction.
T148 27710-27875 Sentence denotes In a recent study of the SARS-CoV-2 genome, researchers found that the NSP6 protein of the virus binds with greater affinity to the endoplasmic reticulum (ER) [136].
T149 27876-28048 Sentence denotes This genetic change may allow the virus to inhibit autophagy via impaired autophagosome processing, which prevents the degradation of viral particles by the lysosome [136].
T150 28049-28288 Sentence denotes There is also evidence that PLP2 is over-expressed in SARS-CoV and MERS-CoV cell lines that also allows the virus to inhibit autophagolysosomal formation and autophagy flux and is likely a method of autophagy inhibition in SARS-CoV-2 [96].
T151 28289-28540 Sentence denotes These studies suggest potential mechanism by which SARS-CoV-2 inhibits autophagy to infect or circumvent host cells pathogenic clearance pathways and limit an adequate immune response similar to other coronaviruses that warrants further investigation.
T152 28541-28685 Sentence denotes The elimination of viruses by autophagy (sometimes termed as virophagy) has been well described for a variety of viral infections [8,84,85,137].
T153 28686-28859 Sentence denotes Although, the virus has multiple ways of entry into the cell, autophagy augmentation provides strategic advantage in reducing viral load by promoting its clearance [90,137].
T154 28860-29048 Sentence denotes As a proof of concept, recent study demonstrated the utility of three different autophagy-inducing drugs, spermidine, MK02206, and niclosamide, in restricting SARS-CoV-2 propagation [138].
T155 29049-29238 Sentence denotes Autophagy induction and related upregulation of overall immunity helps combat exacerbations and is suggested as an immunity boosting strategy as a preventive measure against COVID-19 [139].
T156 29239-29491 Sentence denotes In addition to boosting immunity, dampening viral load, and allowing SARS-COV2 clearance, autophagy induction may provide strategic advantage in the treatment of COVID-19 and prevention of negative outcomes, which makes it a subject of ongoing studies.
T157 29492-29759 Sentence denotes In support of this, autophagy inhibiting drugs, such as hydroxychloroquine (HCQ) that help dampen the immune response in rheumatoid arthritis, malaria, and other illnesses but weakens cellular ability for viral clearance by the critical homeostatic process autophagy.
T158 29760-29982 Sentence denotes Despite early claims that HCQ may provide benefit in treating COVID-19 [90,91,92], it has since been deemed unsafe for use in COVID-19 treatment by the FDA based on randomized double blind placebo control trials [140,141].
T159 29983-30273 Sentence denotes In addition, earlier studies on Middle East respiratory syndrome (MERS) coronavirus [50] provide proof-of-concept data on therapeutic potential of autophagy modulating drugs to combat SARS-COV2 infection, cytokine storm, and the pathogenesis of severe ARDS-like COVID-19 fatal lung disease.
T160 30274-30604 Sentence denotes Prior studies showing a protective role of autophagy induction in other models of ARDS demonstrate the scope of autophagy augmenting strategies in combating SARS-CoV-2 infections (Figure 1) and thus is part of ongoing validation and rapid clinical development studies that may help limit the burden and spread of this novel virus.
T161 30605-30873 Sentence denotes As discussed above for other lung diseases, targeting autophagy to prevent the replication of SARS-CoV-2 is not the only potential benefit of autophagy augmentation for the treatment of COVID-19, but it may also allow the fine-tuning of optimal inflammatory responses.
T162 30874-31093 Sentence denotes As now known, the pathogenesis of SARS-CoV-2-mediated severe COVID-19 involves the activation of numerous pro-inflammatory cytokines as part of the aforementioned cytokine storm causing a hyper-inflammatory state [142].
T163 31094-31355 Sentence denotes In addition to the destruction of the lungs and ARDS associated with COVID-19, this inflammatory response can cause damage to the cardiovascular, nervous, renal, hepatic, and gastrointestinal systems with wide ranging immediate and long-term consequences [142].
T164 31356-31499 Sentence denotes In support of this, studies have demonstrated the role of autophagy in the inflammatory response within the lungs and other organ systems [61].
T165 31500-31620 Sentence denotes As mentioned above, autophagy induction has been demonstrated to attenuate lung inflammation when exposed to a pathogen.
T166 31621-31839 Sentence denotes Thus, autophagy induction to limit the inflammatory response, in addition to infection, has an immense therapeutic potential as an effective treatment for COVID-19 and decreasing the associated mortality and morbidity.
T167 31841-31845 Sentence denotes 4.4.
T168 31846-31871 Sentence denotes Autophagy Defects in COPD
T169 31872-32099 Sentence denotes We and others have described autophagy dysfunction as a prime causative factor utilizing in vitro and animal models of smoke- (cigarette and waterpipe) or eCV (nicotine)-induced lung injury and COPD-emphysema [33,34,39,94,109].
T170 32100-32389 Sentence denotes Moreover, these were validated in human subjects where defective autophagy was verified using human lung tissues from COPD-emphysema subjects, where classical autophagy impairment features, such as aggresome bodies, were associated with the severity and progression of the disease [22,36].
T171 32390-32694 Sentence denotes These aggresome bodies are perinuclear accumulations of misfolded or aggregated proteins, which are poly-ubiquitinated and co-localize with p62 and the autophagy protein microtubule-associated protein 1 light-chain-3B(+) (LC3B+) bodies, and are the key indicators of defective autophagy flux [33,36,143].
T172 32695-32993 Sentence denotes Additionally, we and others have also noted the increase in aggresome body formation in aged mice lungs that correlated with alveolar airspace enlargement (emphysema phenotype), indicating that age-related decline in autophagy contributes to COPD-emphysema development, similar to CS exposure [33].
T173 32994-33242 Sentence denotes Moreover, an increase in emphysema severity (GOLD 0-IV) in smokers with a minimal age difference [33] also correlated with an increase in alveolar senescence, indicating the presence of accelerated lung aging in severe COPD-emphysema subject lungs.
T174 33243-33369 Sentence denotes We further validate smoke-induced accelerated lung aging using aging markers and in vitro and murine models of COPD-emphysema.
T175 33370-33713 Sentence denotes In further studies, a clear mechanistic and protective role of TFEB, the master autophagy regulator, was observed in CS-induced lung disease models where other pathogenic features of COPD-emphysema, such as inflammatory-oxidative stress, senescence, apoptosis, and aggresome formation, were used for the validation of pathogenic roles [34,35].
T176 33714-33934 Sentence denotes In fact, the CS-induced sequestration of TFEB protein into aggresome bodies leads to its decreased availability, which prevents its function as a transcription factor to positively regulate the autophagy process [34,35].
T177 33935-34245 Sentence denotes Moreover, TFEB-mediated autophagy was shown to be protective against oxidative stress and hepatotoxicity induced by ethyl carbamate (a toxicant in CS) [144], suggesting that TFEB-autophagy is a protective mechanism against CS exposure-induced toxicity, not only in the lungs, but in other vital organs as well.
T178 34246-34461 Sentence denotes Additionally, TFEB-mediated autophagy has also been shown to control CS-induced cellular senescence, and bacterial phagocytic clearance, thus highlighting its protective role in CS-induced COPD-emphysema [22,34,35].
T179 34462-34685 Sentence denotes In addition to TFEB, other mechanistic mediators of autophagy have been shown to participate in the sequential dysfunction or impairment of autophagy processes, contributing as a key mediator of COPD-emphysema pathogenesis.
T180 34686-34906 Sentence denotes For example, increased levels of bicaudal D1 (BICD1), an adaptor for the dynein–dynactin motor complex, were found in the peripheral lung tissues of COPD patients, which was associated with increased p62 oligomers [145].
T181 34907-35218 Sentence denotes Additionally, the exposure of bronchial epithelial cells or mice to CS led to increased BICD1 levels, along with defective autophagosome maturation, and an accumulation of BICD1 with p62 and ubiquitin-associated p62-oligomers, thus confirming the mechanistic role of BICD1 in CS-induced autophagy defects [145].
T182 35219-35318 Sentence denotes Dysfunctional autophagy has also been associated with defects in specific cell types of the airway.
T183 35319-35445 Sentence denotes The secretory cells of the airway, such as the club and goblet cells, play an important role in host defense during infection.
T184 35446-35568 Sentence denotes Autophagy has been recently shown to be required to maintain the function of club cells, independent of CS exposure [146].
T185 35569-35820 Sentence denotes Mice deficient in autophagy protein Atg5, demonstrate a diminished expression of the host defense protein secretoglobulin family 1A member 1 (SCGB1A1) and surfactant proteins A1 and D (Sftpa1 and Sftpd), as well as abnormal club cell morphology [146].
T186 35821-35969 Sentence denotes Moreover, a diminished SCGB1A1 expression in club cells correlates with evidence of reduced autophagy in lung tissue from COPD former smokers [146].
T187 35970-36178 Sentence denotes CS exposure has also been demonstrated to cause the accumulation of damaged mitochondrial via impaired mitophagy, which has been demonstrated to play a role in COPD pathogenesis disease progression [147,148].
T188 36179-36388 Sentence denotes Thus, it can be postulated that CS-induced autophagy dysfunction would further deteriorate the structure and function of club cells, resulting in altered or diminished host defense mechanisms in COPD subjects.
T189 36390-36394 Sentence denotes 4.5.
T190 36395-36431 Sentence denotes Autophagy Defects in Cystic Fibrosis
T191 36432-36637 Sentence denotes Cystic fibrosis is a chronic obstructive lung disease which is marked by recurrent infections, chronic inflammatory-oxidative stress, and mucus overproduction that contributes to severe airway obstruction.
T192 36638-36826 Sentence denotes Initial seminal studies by Luciani A et al. established the link between defective CFTR and the presence of aggresome bodies, lung inflammation, and ROS-mediated autophagy inhibition [53].
T193 36827-37200 Sentence denotes We and others have not only validated that defective CFTR-mediated ROS-TG2 pathway drives the crosslinking of Beclin-1, which results in the accumulation of misfolded ΔF508-CFTR into p62+HDAC6+ aggresome bodies leading to autophagy dysfunction, but we have also demonstrated the key central role of autophagy in regulating CF pathogenesis and exacerbations [42,58,149,150].
T194 37201-37342 Sentence denotes These studies describe the specific role of defective autophagy in CF-related chronic infections and resulting inflammatory-oxidative stress.
T195 37343-37568 Sentence denotes In addition, CF macrophages demonstrate impaired phagocytic activity and thus CF patients are more prone to bacterial infections, such as P. aeruginosa and Burkholderia cenocepacia (B. cenocepacia) [45,51,58,106,151,152,153].
T196 37569-37665 Sentence denotes A recent study investigated the precise mechanism of weak autophagic activity in CF macrophages.
T197 37666-38018 Sentence denotes Using the technique of reduced representation bisulfite sequencing (RRBS) to determine the DNA methylation profile, the authors found that the promoter regions of Atg12 in CF macrophages are significantly more methylated as compared to the control WT cells, thereby elucidating a novel mechanism for reduced autophagy activity in CF immune cells [154].
T198 38019-38229 Sentence denotes In a separate study, an increased expression of the microRNA (Mir)c1/Mir17-92 cluster was identified as a potential negative regulator of autophagy in CF macrophages when compared to normal control cells [105].
T199 38230-38387 Sentence denotes Furthermore, the in vivo downregulation of Mir17 and Mir20a, partially restored autophagy gene expression and improved the clearance of B. cenocepacia [105].
T200 38388-38536 Sentence denotes These studies highlight the importance of autophagy as a key protective mechanism in CF exacerbation, and lung disease pathogenesis and progression.
T201 38538-38542 Sentence denotes 4.6.
T202 38543-38567 Sentence denotes Autophagy Defects in IPF
T203 38568-38678 Sentence denotes IPF is a chronic, progressive, and frequently fatal disease associated with aging and dysfunctional autophagy.
T204 38679-38981 Sentence denotes It is accepted that accelerated epithelial cell senescence plays a vital role in IPF pathogenesis by virtue of atypical epithelial–mesenchymal interactions, and insufficient autophagy is attributed as a mechanism of accelerated epithelial cell senescence and myofibroblast differentiation in IPF [155].
T205 38982-39048 Sentence denotes Bleomycin is widely used as a model of drug-induced lung fibrosis.
T206 39049-39187 Sentence denotes The first study to describe the protective role of autophagy in bleomycin-induced lung fibrosis used the Atg4b-deficient mice model [156].
T207 39188-39371 Sentence denotes After 7 days of bleomycin treatment, these mice demonstrated a significantly higher neutrophilic infiltration and inflammatory cytokine production as compared to untreated mice [156].
T208 39372-39584 Sentence denotes Additionally, after 28 days of bleomycin treatment, mice developed extensive lung fibrosis, which was accompanied by an elevated collagen deposition and deregulated expression of extracellular matrix genes [156].
T209 39585-39853 Sentence denotes Similarly, in mice deficient in LC3B (LC3B−/−), bleomycin-mediated lung injury and fibrotic changes were more pronounced, suggesting the protective role of autophagy in bleomycin-induced lung injury and the resulting development of fibrotic lung disease in mice [157].
T210 39854-39975 Sentence denotes Another recent study describes the protective role of the anti-inflammatory cytokine IL-37 in the IPF murine model [158].
T211 39976-40176 Sentence denotes A further mechanistic delve into the mechanism of IL-37-mediated protection showed that it induces Beclin-1-dependent autophagy while downregulating TGFβ1-mediated lung fibroblast proliferation [158].
T212 40177-40390 Sentence denotes Moreover, IL-37 also decreased inflammation and collagen deposition in bleomycin-treated murine lungs while the protective effect was reversed by treatment with 3-methyladinine (3MA), an autophagy inhibitor [158].
T213 40391-40501 Sentence denotes Thus, it is plausible that a decrease in IL-37-mediated autophagy might be involved in the progression of IPF.
T214 40502-40621 Sentence denotes Moreover, the protective effects of autophagy are apparent from this and the other mechanistic studies mentioned above.
T215 40622-40917 Sentence denotes Additional mechanistic evidence comes from a study that showed bleomycin directly binds to annexin A2 (ANXA2) in lung epithelial cells, thereby preventing the nuclear translocation of TFEB; thus, there is an inhibition of the autophagy flux resulting in fibrotic lung disease pathogenesis [159].
T216 40918-41043 Sentence denotes Moreover, torin1-mediated TFEB activation restores autophagy flux and ameliorates bleomycin-induced pulmonary fibrosis [159].
T217 41044-41349 Sentence denotes Autophagy dysfunction is also reported in human lung fibroblasts from IPF patients, and it is believed that defective autophagy is required to maintain a cell death-resistant phenotype in IPF fibroblasts, suggesting that autophagy dysfunction is a profibrotic mechanism and promotes IPF pathogenesis [64].
T218 41350-41551 Sentence denotes Hence, in age-related IPF pathogenesis, autophagy declines with age and the resulting imbalance of inflammatory-oxidative responses is anticipated to mediate the initiation of fibrotic pathophysiology.
T219 41552-41679 Sentence denotes However, further clinical evaluation is needed to evaluate the therapeutic potential of autophagy augmentation in IPF patients.
T220 41681-41683 Sentence denotes 5.
T221 41684-41739 Sentence denotes Autophagy-Mediated CFTR and Immune Response Dysfunction
T222 41740-41884 Sentence denotes The genetic loss of CFTR or a decrease in its expression and/or activity due to environmental insults such as CS leads to autophagy dysfunction.
T223 41885-42160 Sentence denotes An investigation of CFTR-deficient mice or cells isolated from CF subjects revealed an intrinsic defect in autophagy in the absence of CFTR, and the mechanism of defective CFTR-mediated autophagy impairment via the ROS-TG2-Beclin-1 pathway is well established [22,42,53,150].
T224 42161-42426 Sentence denotes Supporting studies demonstrate that autophagy augmentation restores CS-induced CFTR dysfunction, inflammatory-oxidative stress, ceramide accumulation, and COPD-emphysema pathogenesis by rescuing aggresome-bound mutant ΔF508-CFTR to the plasma membrane (PM) [22,35].
T225 42427-42611 Sentence denotes Conversely, restoring CFTR levels by S-nitrosoglutathione (GSNO) augmentation corrects CS-induced autophagy dysfunction, inflammatory-oxidative stress and COPD-emphysema features [62].
T226 42612-42812 Sentence denotes These findings not only highlight the intricate relationship between CFTR and autophagy but also provide a unique therapeutic opportunity to control exacerbations and chronic lung disease progression.
T227 42813-43013 Sentence denotes Several reports have suggested that the inherently elevated inflammatory-oxidative stress in CF cells, primarily due to activated NFκB signaling, could be dampened by autophagy augmentation [124,160].
T228 43014-43241 Sentence denotes Moreover, it’s conceivable that CFTR dysfunction leads to impaired pathogen clearance, as the autophagy-mediated degradation of both intracellular and extracellular pathogens (xenophagy) is well demonstrated [35,45,58,151,161].
T229 43242-43457 Sentence denotes An alternate mechanism called LC3-associated phagocytosis (LAP) is also described, which is similar to the normal macroautophagy pathway but does not involve the formation of a double membrane autophagosome [7,162].
T230 43458-43684 Sentence denotes Nonetheless, LAP assists in the processing of both intracellular and extracellular pathogens, through the recruitment of LC3 to the phagosomal membrane and subsequent delivery to lysosomes for terminal degradation [7,151,162].
T231 43685-43836 Sentence denotes Autophagy per se plays a very crucial role in regulating innate and adaptive immunity both in normal conditions and in response to pathogen challenges.
T232 43837-44050 Sentence denotes Autophagy directly governs key aspects of the innate immune activation, including the secretion of inflammatory mediators, such as cytokines, which are essential to combat different microbial pathogens [7,8,9,84].
T233 44051-44255 Sentence denotes The “inflammasome” is a cytoplasmic multiprotein complex that detects pathogenic microorganisms or other cellular stresses and activates potent pro-inflammatory cytokines such as IL-1β and IL-18 [87,133].
T234 44256-44427 Sentence denotes Although inflammasome activation is an early innate response to protect the host, its prolonged activation can lead to severe hyperinflammation and tissue injury [47,130].
T235 44428-44644 Sentence denotes Recent studies suggest that autophagy is a negative regulator of inflammasome activation as a deficiency of autophagy components such as LC3B or Beclin-1 promotes NLRP3-dependent inflammasome activation [47,130,133].
T236 44645-44948 Sentence denotes Apart from its regulation of inflammasome, autophagy also suppresses the overactivation of other inflammation-inducing factors such as NFκB, suggesting a general protective role of autophagy in keeping a check of uncontrolled innate immune activation that may contribute to lung injury [11,37,38,54,55].
T237 44949-45178 Sentence denotes In the adaptive immune system, functional autophagy is required for the survival, development, maturation, and function of immune cells such as CD4+ T cells, CD8+ T cells, B cells, neutrophils, and monocytes [7,9,84,163,164,165].
T238 45179-45347 Sentence denotes Moreover, in dendritic cells (DC’s), antigen processing and presentation to MHC-II is dependent on the autophagic generation of suitable peptides [9,20,88,163,164,165].
T239 45348-45569 Sentence denotes Additionally, antigen presentation to CD8+ T cells on MHC-I is also dependent on autophagy, thus implicating its indispensable role in generating an adequate immune response to bacterial and viral pathogens [163,164,165].
T240 45570-45808 Sentence denotes Hence, autophagy promotes adequate antigen presentation to T cells in numerous infection models, thereby facilitating a robust adaptive immune response and further demonstrating the necessary functional role autophagy plays in infections.
T241 45809-45955 Sentence denotes The lack of functional CFTR in macrophages results in an increased production of inflammatory cytokines, and impaired pathogen clearance capacity.
T242 45956-46161 Sentence denotes The diminished expression of HLA-DQ and HLA-DR (MHC-II molecules) on monocytes derived from ΔF508-CFTR homozygous CF subjects [166], might explain the impaired pathogen clearance ability of CF macrophages.
T243 46162-46303 Sentence denotes In addition, CFTR deficiency has been implicated in diminished Treg effector function and a more pronounced Th2-biased immune response [167].
T244 46304-46462 Sentence denotes The CF defect has also been shown to affect the activation of neutrophils [168], which are the cells responsible for the first line of defense in the airways.
T245 46463-46857 Sentence denotes Although, airway epithelial cells and lung-resident macrophages sense the invading pathogens and secrete a plethora of factors to induce the recruitment and activation of neutrophils, neutrophils from CF subjects have diminished phagocytic potentials by virtue of the reduced cell surface expression of toll-like receptors (TLRs) and disrupted chloride transport to the phagolysosome [169,170].
T246 46858-46931 Sentence denotes Thus the CFTR mutation in CF results in impaired bacterial killing [171].
T247 46932-47079 Sentence denotes Moreover, CF neutrophils also demonstrate an increased capacity to release their primary granule contents such as MPO and neutrophil elastase (NE).
T248 47080-47179 Sentence denotes The uncontrolled release of these enzymes causes lung tissue damage and severe airway inflammation.
T249 47180-47509 Sentence denotes We have shown that P. aeruginosa LPS-induced MPO levels can be reduced by treatment with the histone deacetylase (HDAC) inhibitor, suberoylanilide hydroxamic acid (SAHA), plausibly by restoring the trafficking of ΔF508-CFTR, suggesting that a functional CFTR is required to keep a tab on uncontrolled neutrophil activation [172].
T250 47510-47715 Sentence denotes Mechanistically, an absence or dysfunction of CFTR in neutrophils results in the deactivation of the guanosine triphosphate (GTP)-binding protein Rab27a, which causes impaired granule exocytosis [168,172].
T251 47716-47945 Sentence denotes Several studies now agree that the pharmacological inhibition of CFTR or the mutant ΔF508-CFTR is sufficient to cause deregulated neutrophil activation via the activation of the NFκB pathway, resulting in hyperinflammation [172].
T252 47946-48069 Sentence denotes Therefore, autophagy and CFTR share an intimate relationship in terms of regulating the immune response against infections.
T253 48070-48225 Sentence denotes Moreover, the rescue of mutant CFTR to the PM corrects the autophagy-mediated immune dysfunction, controlling chronic lung disease pathogenesis (Figure 1).
T254 48227-48229 Sentence denotes 6.
T255 48230-48296 Sentence denotes Autophagy-CFTR Dysfunction Induces Acute and Chronic Exacerbations
T256 48297-48422 Sentence denotes As discussed above, many patients with chronic respiratory diseases such as COPD and CF face acute and chronic exacerbations.
T257 48423-48568 Sentence denotes These pulmonary exacerbations are characterized by a worsening lung function, significantly below what is normal for their conditions [4,31,173].
T258 48569-48841 Sentence denotes These exacerbations are caused by environmental exposures or bacterial and viral infections that result in further deterioration of the patient’s condition [4,31,173,174,175], leading to hospitalization for individuals causing increased morbidity and mortality [4,31,173].
T259 48842-48958 Sentence denotes Exacerbations also pose a significant financial burden for patients with chronic respiratory diseases [1,2,176,177].
T260 48959-49168 Sentence denotes Since pulmonary exacerbations are commonly triggered by infections, the autophagy dysfunction seen in these chronic conditions plays a role in the pathogenesis of this state via the mechanisms discussed above.
T261 49169-49329 Sentence denotes A common pathogen that colonizes the lungs of individuals with chronic respiratory diseases and can lead to exacerbations is P. aeruginosa [4,31,44,58,173,178].
T262 49330-49496 Sentence denotes Studies have demonstrated that defects in CFTR impair the ability of cells to clear P. aeruginosa infections via autophagy, especially in patients with CF [22,40,53].
T263 49497-49669 Sentence denotes Furthermore, it has been shown that the induction of autophagy is able to ameliorate autophagy dysfunction and promote the clearance of P. aeruginosa infections [35,45,58].
T264 49670-50003 Sentence denotes As previously mentioned, CS exposure can also cause CFTR dysfunction, where a recent investigation demonstrated that CS exposure decreased CFTR expression while a treatment of CS-exposed macrophages with the autophagy inducer fisetin, which works by modulating autophagosome degradation, significantly recovered CFTR expression [35].
T265 50004-50120 Sentence denotes This same investigation showed that the CS-induced inhibition of CFTR decreased the clearance of P. aeruginosa [35].
T266 50121-50269 Sentence denotes This impaired clearance was then alleviated by autophagy induction with fisetin, supporting the findings of other previously mentioned studies [35].
T267 50270-50386 Sentence denotes Hence, CFTR-autophagy dysfunction in chronic lung diseases such as CF and COPD leads to P. aeruginosa exacerbations.
T268 50387-50527 Sentence denotes Similarly, Burkholderia cepacia (B. cepacia), an opportunistic infection that afflicts 3–5% of CF patients, can provoke exacerbations [151].
T269 50528-50718 Sentence denotes It has been found that macrophages can kill B. cepacia within autophagolysosomes; however, macrophages with ΔF508-CFTR lacked the bacteria in autophagolysosomes indicating dysfunction [151].
T270 50719-50908 Sentence denotes When these macrophages were treated with the autophagy inducer rapamycin, ΔF508-CFTR macrophages were able to fight the B. cepacia infection and reduce the resulting inflammation [153,179].
T271 50909-51124 Sentence denotes This demonstrates the importance of CFTR-dependent autophagy in not only clearing bacteria that can provoke pulmonary exacerbations, but also decreasing inflammation that can lead to worsened lung functions as well.
T272 51125-51214 Sentence denotes In regard to viral infections, CFTR-autophagy dysfunction limits viral clearance as well.
T273 51215-51368 Sentence denotes In a recent study, it was determined that CFTR-deficient mice infected with RSV had an impaired ability to clear the virus compare to control mice [180].
T274 51369-51552 Sentence denotes Similarly, despite similar cytokine responses, respiratory epithelial cells with ΔF508-CFTR had a higher viral load when infected with rhinovirus in comparison to control cells [181].
T275 51553-51805 Sentence denotes From what we know about CFTR-autophagy’s role in pathogen clearance, it is likely that the observed findings in this study are a result of decreased autophagy in the ΔF508-CFTR cells that leads to decreased rhinovirus clearance and a higher viral load.
T276 51806-51936 Sentence denotes Thus, proper CFTR-dependent autophagy function is necessary for the clearance of both bacterial and viral pathogens in the airway.
T277 51937-52081 Sentence denotes Besides infection, CFTR-autophagy dysfunction can lead to an impaired clearance of cellular debris and products that would normally be degraded.
T278 52082-52233 Sentence denotes One such product is ceramide, which in response to CFTR-autophagy dysfunction can accumulate in aggresome bodies within cells [22,110,182,183,184,185].
T279 52234-52409 Sentence denotes Ceramide accumulation has been observed in both CF patients with CFTR mutations [182,183,186] and COPD patients who have acquired CFTR dysfunction due to CS exposure [22,110].
T280 52410-52534 Sentence denotes In the presence of CS, ceramide has been found to accumulate in p62+ aggresome bodies, indicating autophagy impairment [22].
T281 52535-52797 Sentence denotes As CFTR-autophagy becomes impaired in both CF and COPD, cells have chronically elevated intracellular levels of ROS altering cellular homeostasis, causing exacerbations and accelerating the pathogenesis and progression of these respiratory diseases [22,110,182].
T282 52798-52976 Sentence denotes Moreover, the deleterious effect of ceramide accumulation on CFTR-autophagy has been demonstrated to directly impair defenses against bacteria [52,184,186,187] and viruses [188].
T283 52977-53183 Sentence denotes As such, ceramide accumulation as a result of either inherent or acquired CFTR dysfunction leads to autophagy impairment causing a diminished immune response and bacterial colonization or viral replication.
T284 53184-53408 Sentence denotes Hence, dysfunctional CFTR and autophagy dysfunction go hand in hand with an increased susceptibility of individuals to pathogens that significantly decrease lung function and cause acute and chronic exacerbations (Figure 1).
T285 53410-53412 Sentence denotes 7.
T286 53413-53494 Sentence denotes CFTR- Autophagy Dysfunction and Pathogenesis of Chronic Obstructive Lung Diseases
T287 53495-53890 Sentence denotes The homeostatic autophagy process in the airways is prone to dysregulation by a variety of factors such as exposure to first- or second-hand CS [40], eCV [39], biomass smoke [14,43], waterpipe smoke (WPS) [94], wildfire smoke [189], environmental pollution [61], genetic polymorphisms [53,61,149], aging [190], obesity [191,192], and changes in the expression and/or activity of CFTR [22,35,53].
T288 53891-54166 Sentence denotes Elevated levels of ROS/RNS ensuing from exposure to the above-described risk factors is the primary driver of autophagy impairment (Figure 1), which is considered a central mechanism for the advent of inflammatory-oxidative stress, cellular senescence, and apoptosis [62,94].
T289 54167-54342 Sentence denotes These potentially deleterious changes result in the initiation and progression of COPD-emphysema, as they correlate with the severity of emphysema in COPD subjects [22,33,62].
T290 54343-54533 Sentence denotes We and others have demonstrated the important role of transcription factor-EB (TFEB), the master autophagy regulator, in controlling inflammatory-oxidative and immune signaling [34,143,193].
T291 54534-54831 Sentence denotes In a relatively recent study, we showed that CS-induced accumulation or trapping of TFEB proteins into perinuclear aggresome bodies prevents it from entering the nucleus and performing its function as an autophagy regulating transcription factor, thereby culminating in autophagy dysfunction [34].
T292 54832-55037 Sentence denotes These findings were confirmed in human lung tissue sections from smoker and nonsmoker COPD subjects, where the perinuclear accumulation of TFEB into aggresome bodies increases with emphysema severity [34].
T293 55038-55264 Sentence denotes Moreover, smokers showed a more prominent increase in TFEB-aggresome localization as compared to nonsmokers, emphasizing that CS exposure leads to defective autophagy via functional trapping of TFEB into aggresome bodies [34].
T294 55265-55542 Sentence denotes It is evident from innumerable studies that a complete loss or decrease in the levels of functional WT-CFTR from the PM due to genetic mutations leads to several deleterious changes in the airways that ultimately results in obstructive lung disease pathogenesis in CF subjects.
T295 55543-55917 Sentence denotes Specifically, a decrease in/loss of WT-CFTR is causally related to increased ROS-mediated inflammatory-oxidative stress, mucus hypersecretion, elevated ceramide levels, and hampered mucociliary clearance resulting in an increased incident of recurrent and chronic pulmonary infections, all of which result in chronic obstructive pathologies in CF airways [15,51,53,110,194].
T296 55918-56167 Sentence denotes It is now well documented that CS exposure [22,40,63,107,108], eCV [39,195], or certain infectious agents [196,197,198] also induce a decrease in the activity or expression of CFTR in the airways and was aptly described as acquired CFTR dysfunction.
T297 56168-56316 Sentence denotes As expected, CS-induced ROS and the resulting oxidative stress was found to be the main cause of acquired CFTR dysfunction in COPD [62,107,108,109].
T298 56317-56634 Sentence denotes Moreover, the mechanistic confirmation of the role of acquired CFTR dysfunction in COPD pathogenesis comes from studies which showed that the pharmacological rescue of mutant CFTR to the PM was able to correct CS-induced inflammatory-oxidative stress, autophagy impairment, and COPD-emphysema pathogenesis [14,42,62].
T299 56635-56928 Sentence denotes Another important mechanism which plays a crucial pathogenic role in both CF and COPD-emphysema is ceramide accumulation (Figure 1), and numerous studies have highlighted that a loss or decrease in CFTR and/or CS exposure leads to an increase in ceramide levels [22,52,93,110,182,183,186,188].
T300 56929-57174 Sentence denotes Our earlier studies described a direct correlation between a lack of lipid-raft CFTR expression and CS-induced apoptosis along with defective autophagy and the progression of COPD-emphysema via ceramide or lactosylceramide accumulation [93,110].
T301 57175-57520 Sentence denotes Lately, we also demonstrated that autophagy augmentation alleviates CS-induced CFTR dysfunction, ceramide accumulation (lipophagy impairment), and resulting COPD-emphysema pathogenesis [22], thus demonstrating that autophagy and CFTR share an interconnected biology crucial for the initiation and progression of chronic lung diseases (Figure 1).
T302 57521-57690 Sentence denotes We further went on to demonstrate that CS-induced autophagy dysfunction and the dysfunction of its component lipophagy lead to intracellular ceramide accumulation [110].
T303 57691-57797 Sentence denotes Meanwhile, acquired CFTR dysfunctions caused ASM activation-dependent membrane ceramide accumulation [22].
T304 57798-58050 Sentence denotes The pathogenic role of ceramide has also been implicated in CF lung disease, wherein it mediates the inflammation, apoptosis, and increased susceptibility to P. aeruginosa infection [183,186,199], and is elevated in the airways of CF mice and patients.
T305 58051-58206 Sentence denotes Mechanistically, it was proven that the ROS-dependent activation of acid sphingomyelinase (ASM) resulted in increased membrane ceramide accumulation [200].
T306 58207-58382 Sentence denotes Thus, several ASM inhibitors have been tested and were shown to reduce ceramide accumulation along with resulting infection and inflammation in the lungs of CF mice [186,200].
T307 58383-58684 Sentence denotes Therefore, there is strong evidence that CFTR-autophagy dysfunction is a prime factor that promotes multiple host destructive phenomena, including inflammatory-oxidative stress and recurrent infection-related exacerbations, which eventually contribute to chronic obstructive lung disease pathogenesis.
T308 58686-58688 Sentence denotes 8.
T309 58689-58804 Sentence denotes Autophagy Augmentation Strategies to Mitigate the Pathogenesis and Progression of Chronic Obstructive Lung Diseases
T310 58805-59059 Sentence denotes As discussed above, autophagy-CFTR dysfunction plays a vital role in regulating the pathogenesis of chronic obstructive lung diseases, including facilitating recurrent infections leading to severe disease exacerbations and an increased risk of mortality.
T311 59060-59272 Sentence denotes Therefore, it is apparent that pharmacological interventions targeted to correct the autophagy-CFTR dysfunction provides a lucrative therapeutic strategy to control chronic obstructive lung diseases pathogenesis.
T312 59273-59602 Sentence denotes Indeed, using in vitro and pre-clinical murine models, we and others have shown that autophagy augmentation mitigates several pathogenic features of chronic lung diseases, such as inflammatory-oxidative stress, apoptosis, cellular senescence, lung tissue damage, and bacterial or viral infections [22,35,42,45,58,62,149,151,153].
T313 59603-59868 Sentence denotes The utility of pharmacological or natural compounds that can alleviate autophagy-CFTR dysfunction has been comprehensively investigated in both CS-induced in vitro and pre-clinical murine models of CS exposure, with or without P. aeruginosa co-infection [34,35,42].
T314 59869-60291 Sentence denotes We have extensively tested the pre-clinical therapeutic efficacy of cysteamine, a naturally occurring FDA-approved aminothiol compound, which is a known proteostasis and autophagy regulator that induces autophagosome formation, in controlling various pathogenic features of CS- and aging-induced inflammatory-oxidative stress, apoptosis, cellular senescence, pathogen clearance, lung injury, and COPD-emphysema [22,33,94].
T315 60292-60606 Sentence denotes Even though cysteamine offers several beneficial attributes such as its antioxidant, bactericidal, mucolytic, and, the most promising, CFTR-rescuing potential that corrects the CS-induced acquired CFTR dysfunction, there are some limitations such as the optimization of beneficial dose and airway delivery methods.
T316 60607-60764 Sentence denotes We and others have devised strategies such as nano/dendrimer-based formulations which can be efficiently delivered through intranasal inhalation [42,45,149].
T317 60765-61015 Sentence denotes The more specific targeting of pulmonary tissues using nano/dendrimer-based drugs improves the therapeutic potential while mitigating some system-wide side effects that may be associated with systemic and nontargeted delivery methods [42,45,149,201].
T318 61016-61307 Sentence denotes We believe that cysteamine or its nano/dendrimer formulations have a significant potential of controlling COPD-emphysema pathogenic features, including recurrent exacerbations, based on its known pre-clinical efficacy and ongoing clinical evaluations in controlling obstructive lung disease.
T319 61308-61534 Sentence denotes Our relatively recent study using GSNO, an endogenously occurring nitric oxide donor, highlights the biological significance of CS-induced CFTR dysfunction-related autophagy impairment in mediating COPD-emphysema pathogenesis.
T320 61535-61731 Sentence denotes We showed that an augmentation of GSNO decreases cigarette smoke extract (CSE)-induced ROS activation and autophagy-flux impairment by rescuing the aggresome-bound perinuclear CFTR to the PM [62].
T321 61732-62116 Sentence denotes Furthermore, using a preclinical COPD-emphysema murine model, we demonstrated that chronic CS (Ch-CS) induced an increase in inflammatory cytokines in BALF, aggresome formation, CFTR-aggresome localization, oxidative/nitrosative stress, and apoptosis, and the emphysematous changes (alveolar airspace enlargement) were significantly improved by augmenting the airway GSNO levels [62].
T322 62117-62285 Sentence denotes Thus, this study provides proof-of-concept evidence that GSNO augmentation could be further tested as a potential strategy to correct CS-induced CFTR-autophagy defects.
T323 62286-62549 Sentence denotes Apart from cysteamine and GSNO, we also tested the potential of other FDA-approved autophagy-inducing drugs, such as gemfibrozil (GEM), which induces lysosome formation, and fisetin, in controlling CS-induced autophagy dysfunction and hampered pathogen clearance.
T324 62550-62742 Sentence denotes Our study showed that CS/CSE-induced TFEB/autophagy impairment, inflammatory-oxidative stress, apoptosis, and senescence can be mitigated by treatment with GEM/fisetin via TFEB induction [34].
T325 62743-62956 Sentence denotes In a subsequent investigation, we demonstrated that CSE-induced autophagy dysfunction in macrophages is a critical mechanism of phagocytosis defects and the resulting diminished clearance of P. aeruginosa [33,35].
T326 62957-63224 Sentence denotes The autophagy-inducing antioxidant fisetin was able to restore the CS-induced phagocytosis defect and facilitate P. aeruginosa clearance [35], suggesting the potential of autophagy-inducing strategies in controlling exacerbations prevalent in COPD-emphysema subjects.
T327 63225-63411 Sentence denotes The therapeutic potential of autophagy augmenting drugs has been extensively investigated in controlling chronic CF lung disease and associated pulmonary infection-related exacerbations.
T328 63412-63661 Sentence denotes There have been extensive studies on the use of rapamycin in controlling CF-related lung infections, but its clinical use is hampered due to its potent immunosuppressive property and certain reports of significant lung toxicity [5,6,44,151,153,202].
T329 63662-63846 Sentence denotes Lately, the efficacy of the thymic peptide, Thymosin α-1 (Tα1), was demonstrated in correcting the basic defect in CF, which is the restoration of misfolded ΔF508-CFTR to the PM [203].
T330 63847-63995 Sentence denotes Tα1 possesses anti-inflammatory properties and is also known to induce autophagy [204], which could be its mechanism of action to rescue ΔF508-CFTR.
T331 63996-64165 Sentence denotes Nonetheless, future pre-clinical and clinical studies will be essential before it could be any therapeutic benefit in CF-related autophagy dysfunction and exacerbations.
T332 64166-64395 Sentence denotes The utility of cysteamine, a potent antioxidant drug with autophagy-inducing potential, has been widely tested in CF in vitro, in vivo models, and is currently being investigated in phase 2 human clinical trials [58,205,206,207].
T333 64396-64566 Sentence denotes However, a previously completed study of 10 patients with the ΔF508-CFTR mutation demonstrated a significant improvement in CFTR function with cysteamine treatment [208].
T334 64567-64838 Sentence denotes Similarly, our recent studies validated cysteamine’s extensive repertoire of protective mechanisms in CF, and demonstrated for the first time that cysteamine was able to control CS-induced lipophagy impairment and the resulting ceramide accumulation in murine lungs [22].
T335 64839-65036 Sentence denotes This finding might have implications in controlling both COPD and CF-related infections and exacerbations, knowing the deleterious role of ceramide in promoting pulmonary infections in COPD and CF.
T336 65037-65264 Sentence denotes In addition, autophagy dysfunction has been now widely accepted as a pathogenic mechanism in IPF, and thus strategies to augment autophagy are justified as relevant potential interventions in controlling IPF pathogenesis [209].
T337 65265-65435 Sentence denotes Indeed, some recent studies have shown that autophagy mitigates IPF pathogenesis by regulating the fibroblast apoptosis and senescence of alveolar epithelial cells [209].
T338 65436-65629 Sentence denotes Moreover, a recent report describes the utility of IL-37 in reducing the bleomycin-induced inflammation and collagen deposition in murine lungs by increasing Beclin-1-dependent autophagy [158].
T339 65630-65877 Sentence denotes Therefore, autophagy augmentation strategies likely have a strong potential to control chronic obstructive lung disease pathogenesis, including suppressing the severe pulmonary exacerbations which frequently result in patient mortality (Figure 2).
T340 65879-65881 Sentence denotes 9.
T341 65882-65893 Sentence denotes Perspective
T342 65894-65977 Sentence denotes The burden of exacerbations on the health care system is substantial [1,3,177,210].
T343 65978-66194 Sentence denotes For patients with COPD in the United States, the average annual health care costs associated with their condition was estimated to be USD 9981; meanwhile, the average cost to society was USD 30,826 per patient [211].
T344 66195-66368 Sentence denotes Similarly, CF exacerbations were demonstrated to cost Medicaid on average between USD 44,589 and USD 116,169 annually with the costs increasing with the age of patients [2].
T345 66369-66468 Sentence denotes Another study found that the average cost per episode of all CF exacerbations was USD 12,784 [176].
T346 66469-66681 Sentence denotes As such, investigating new methods to prevent recurrent exacerbations is necessary to lower the burden on the health care system while improving the quality of life for patients with chronic pulmonary conditions.
T347 66682-66853 Sentence denotes The potential of autophagy augmenting therapeutics to correct CFTR-autophagy dysfunction and resulting exacerbations provides a possible solution to this issue (Figure 2).
T348 66854-67022 Sentence denotes As a proof of concept, numerous recent studies have demonstrated the potential of targeting CFTR-autophagy dysfunction as a method for reducing recurrent exacerbations.
T349 67023-67180 Sentence denotes One drug that has shown promise in alleviating autophagy impairment to provide possible therapeutic benefits in the treatment of exacerbations is cysteamine.
T350 67181-67382 Sentence denotes Cysteamine is an FDA approved drug for the treatment of cystinosis; however, it also possesses antioxidant, anti-inflammatory, autophagy-inducing, mucolytic, and anti-bacterial properties [58,205,207].
T351 67383-67577 Sentence denotes Recently, Ferrari et al. demonstrated that cysteamine could re-establish P. aeruginosa clearance in macrophages with the ΔF508-CFTR deletion by salvaging ΔF508-CFTR function in macrophages [58].
T352 67578-67760 Sentence denotes This restoration of function allowed macrophages to both increase the internalization and clearance of P. aeruginosa via a Beclin-1-mediated initiation of the autophagy pathway [58].
T353 67761-67896 Sentence denotes This reveals a possible therapy to restore both CFTR and autophagy function in CF patients that could limit P. aeruginosa colonization.
T354 67897-68142 Sentence denotes An improved clearance of P. aeruginosa in CF patients is especially important due to the prevalence of P. aeruginosa infections in exacerbations, and a drug that improves the immune response in this way offers a method to decrease exacerbations.
T355 68143-68213 Sentence denotes Studies exploring cysteamine-dendrimers have revealed similar results.
T356 68214-68421 Sentence denotes Two of our recent studies demonstrated that cysteamine-based dendrimers were able to not only decrease ΔF508-CFTR aggregation, but also rescue the protein to increase the plasma membrane expression [45,149].
T357 68422-68598 Sentence denotes Moreover, these investigations showed that this recue of CFTR by the cysteamine-dendrimers alleviated the autophagy impairment associated with the ΔF508-CFTR mutation [45,149].
T358 68599-68743 Sentence denotes This alleviation of CFTR-autophagy impairment was further shown to increase the clearance and killing of P. aeruginosa in both studies [45,149].
T359 68744-68871 Sentence denotes Hence, cysteamine-based dendrimers provide a therapeutic option in the treatment of both acute and chronic exacerbations in CF.
T360 68872-69074 Sentence denotes Cysteamine’s dendrimer-based formulation also proved beneficial for clearing P. aeruginosa, and thus has potential for treating other infections in CF and non-CF patients who are prone to exacerbations.
T361 69075-69313 Sentence denotes The added advantage of this intervention strategy is that exacerbations in respiratory diseases including those with CFTR dysfunction may be treated and prevented without antibiotics, where multidrug-resistant (MDR) infections are common.
T362 69314-69477 Sentence denotes Further studies into the therapeutic potential of other autophagy inducers for exacerbations in chronic respiratory diseases have shown promise as well (Figure 2).
T363 69478-69653 Sentence denotes These studies have demonstrated that rapamycin can induce autophagy and aid in the killing of different types of bacteria that are known to cause exacerbations [6,44,153,202].
T364 69654-69843 Sentence denotes Similarly, fisetin, which is an over the counter antioxidant used for brain health, induces autophagy [34,43] to improve bacterial clearance by ameliorating CFTR-autophagy dysfunction [35].
T365 69844-69965 Sentence denotes Thus, the use of various autophagy inducers shows promise in restoring the CFTR-autophagy pathway to treat exacerbations.
T366 69966-70182 Sentence denotes However, future studies and clinical trials need to be conducted to evaluate and standardize the safety and efficacy of these treatments to provide benefit in human subjects as a part of ongoing clinical development.
T367 70183-70392 Sentence denotes Another reason to explore treatments that restore the CFTR-autophagy function to treat exacerbations is that the current first-line treatment for exacerbations usually includes antibiotics [4,173,210,212,213].
T368 70393-70546 Sentence denotes In situations where patients experience severe exacerbations, they are often hospitalized and given powerful intravenous (IV) antibiotics [4,31,173,176].
T369 70547-70640 Sentence denotes This is part of what plays into the exorbitant costs associated with recurrent exacerbations.
T370 70641-70789 Sentence denotes When looking specifically at exacerbations requiring hospitalization and IV-antibiotics, the cost is USD 36,319 per exacerbation for patients [176].
T371 70790-71041 Sentence denotes This frequent use of antibiotics in both the out-patient and in-patient treatment of exacerbations causes bacteria to develop MDR, which poses a significant issue for patients as the treatment of future infections becomes more difficult [151,214,215].
T372 71042-71129 Sentence denotes In fact, many pathogens that cause exacerbations have been found to have MDR [214,215].
T373 71130-71288 Sentence denotes As more bacteria demonstrate MDR, more powerful antibiotics are needed to fight off infections, but these powerful antibiotics can have negative side effects.
T374 71289-71436 Sentence denotes As such, researchers have begun investigating the potential of targeting the autophagy pathway to fight off the MDR bacteria causing exacerbations.
T375 71437-71590 Sentence denotes One recent study explored the potential of cysteamine to improve the clearance and killing of different MDR bacteria by macrophages in CF patients [206].
T376 71591-71778 Sentence denotes The researchers demonstrated that there was a significantly increased clearance of B. cenocepacia, B. multivorans, and P. aeruginosa by alveolar macrophages treated with cysteamine [206].
T377 71779-71985 Sentence denotes Further exploration revealed a decrease in the markers of autophagy impairment in these cysteamine-treated macrophages, along with an increase in expression of CFTR on the membrane of the macrophages [206].
T378 71986-72164 Sentence denotes Thus, it can be concluded that cysteamine has the ability to promote host clearance of MDR pathogens in pulmonary exacerbations via the alleviation of CFTR-autophagy dysfunction.
T379 72165-72300 Sentence denotes A similar finding was found in a study that explored a novel autophagy inducer that works by initiating autophagosome formation, AR-13.
T380 72301-72529 Sentence denotes The investigators in this study demonstrated that AR-13 on its own was able to significantly reduce the infectious burden of methicillin-resistant Staphylococcus aureus and P. aeruginosa in both CF and non-CF immune cells [152].
T381 72530-72700 Sentence denotes Meanwhile, in the case of B. cenocepacia, AR-13 in combination with antibiotics was able to significantly improve the bacterial clearance from infected macrophages [152].
T382 72701-72805 Sentence denotes This improved bacterial clearance was attributed to the alleviation of CFTR-autophagy dysfunction [152].
T383 72806-72942 Sentence denotes Hence, therapeutics that aim to restore CFTR-autophagy function demonstrate promise in fighting MDR infections that cause exacerbations.
T384 72943-73190 Sentence denotes If clinical trials of these drugs were to show promise, they may decrease the length of hospitalization and recurrence of exacerbations to decrease both the costs and decreased quality of life faced by individuals with chronic respiratory disease.
T385 73191-73317 Sentence denotes Moreover, the fact that these drugs have been demonstrated to work by inducing autophagy is critical in fighting MDR bacteria.
T386 73318-73499 Sentence denotes Since the mechanism involves the host immune response and there would be less of a need for antibiotics, there is the possibility of decreased incidence of MDR bacteria development.
T387 73500-73575 Sentence denotes However, bacteria are not the only pathogens responsible for exacerbations.
T388 73576-73682 Sentence denotes Viruses are also a common cause of exacerbations in patients with chronic respiratory diseases [4,31,173].
T389 73683-73775 Sentence denotes However, the treatment of viruses is significantly different than the treatment of bacteria.
T390 73776-73864 Sentence denotes For most bacteria, there is an antibiotic that can be prescribed to fight the infection.
T391 73865-74002 Sentence denotes On the other hand, most viruses tend to be treated with supportive care due to the lack of antiviral therapies for many types of viruses.
T392 74003-74246 Sentence denotes As such, being able to clear viruses via autophagy/Tvirophagy may provide a unique therapeutic benefit in both reducing the severity of viral infections and decreasing the duration of viral infections, resulting in a decrease in exacerbations.
T393 74247-74376 Sentence denotes The focus on targeting autophagy to treat exacerbations in lieu of antiviral medications is limited but is gaining more interest.
T394 74377-74498 Sentence denotes One recent study has demonstrated the promise of budesonide, a corticosteroid, in the treatment of rhinovirus infections.
T395 74499-74629 Sentence denotes Rhinovirus causes the common cold and is a common viral cause of exacerbations in CF [32,175], asthma [32,216], and COPD [32,217].
T396 74630-74754 Sentence denotes In this study, researchers found that intranasal budesonide decreased the viral load of rhinovirus in patients’ lungs [218].
T397 74755-74978 Sentence denotes The investigators determined the antiviral effect of budesonide was due to autophagy induction as autophagy inhibition with chloroquine and bafilomycin A1 both significantly reduced the antiviral effect of budesonide [218].
T398 74979-75155 Sentence denotes Similarly, a study performed with dexamethasone, another corticosteroid, demonstrated that it is an effective treatment of rhinovirus through autophagy induction as well [219].
T399 75156-75272 Sentence denotes Thus, there is promise in treating and preventing exacerbations caused by rhinovirus using autophagy-inducing drugs.
T400 75273-75562 Sentence denotes In theory, targeting the induction of autophagy should provide a therapeutic mechanism for the treatment of other viruses that cause exacerbations in patients with chronic respiratory disease due to the role of autophagy in the immune response in many viruses, yet more research is needed.
T401 75563-75734 Sentence denotes In addition to showing promise in targeting viruses that cause exacerbations, the induction of autophagy may also aid in fighting novel viruses that can lead to pandemics.
T402 75735-75877 Sentence denotes For example, the novel coronavirus SARS-CoV2-mediated human respiratory infection, leading to COVID-19, was first reported in late 2019 [137].
T403 75878-75972 Sentence denotes By March 2020, the World Health Organization had declared a pandemic in response to the virus.
T404 75973-76232 Sentence denotes SARS-CoV-2 has caused numerous deaths, due to lack of a potent effective treatment, where antivirals such as remdesevir, favipiravir, etc., although minimally effective in reducing the hospitalization time of severe lung disease subjects, are in short supply.
T405 76233-76552 Sentence denotes Moreover due to the novel nature of the virus, susceptible population groups and aerosol-based rapid transmission, we see variations in the control of transmission and mortality between different countries, where mitigation measures are dependent on socio-economic, health care disparities and political will [137,220].
T406 76553-76812 Sentence denotes As such, there is a need to rapidly deliver on potent treatments in addition to vaccines, and autophagy augmentation with drugs that are FDA-approved for other conditions (Figure 2), provide significant potential for clinical validation and rapid translation.
T407 76813-77142 Sentence denotes In fact, a recent pre-print study that we mentioned above has investigated the use of spermidine (an autophagy inducer), MK-2206 (an AKT inhibitor), and niclosamide (a Beclin-1 stabilizer) in the treatment of COVID-19, and has been found to demonstrate some therapeutic benefits as an antiviral treatment against the virus [138].
T408 77143-77217 Sentence denotes Thus, autophagy induction may provide a beneficial treatment of the virus.
T409 77218-77305 Sentence denotes However, further investigation into these drugs and other autophagy inducers is needed.
T410 77306-77460 Sentence denotes Still, the mechanism of autophagy induction may prove crucial as a treatment of COVID-19 over classical antivirals and provide a tool to end the pandemic.
T411 77461-77659 Sentence denotes This mechanism may also prevent a future epidemic or pandemic by offering possible treatments to novel viruses without vaccines and antivirals that take significant development time for each strain.
T412 77660-77763 Sentence denotes Therefore, targeting and inducing the autophagy pathway is an area of tremendous clinical significance.
T413 77764-78026 Sentence denotes Autophagy-inducing drugs may be necessary for overcoming the CFTR-autophagy impairment found in many chronic respiratory diseases to prevent exacerbations and improve the morbidity and mortality for patients while cutting health care costs for these individuals.
T414 78027-78179 Sentence denotes Moreover, autophagy-inducing drugs offer the ability to fight pathogens without causing MDR bacteria and the need to develop strain specific antivirals.
T415 78180-78472 Sentence denotes As a result, an autophagy induction intervention strategy to handle MDR bacterial infections or novel viral infections provides significant benefits in terms of controlling exacerbations, whereas autophagy induction with drugs currently approved for other conditions allows rapid translation.
T416 78473-78651 Sentence denotes Moreover, the proposed autophagy augmenting therapeutic strategy also provides a possible treatment in situations where it is not possible to develop an antiviral for a pathogen.
T417 78652-78759 Sentence denotes Furthermore, autophagy induction also can offer an effective way to treat current recurring MDR infections.
T418 78760-79039 Sentence denotes Hence, future clinical studies need to expand their scope beyond the horizon of antibiotics and antivirals for the treatment of many respiratory diseases and begin investigating the therapeutic benefits that autophagy augmenting drugs may have in a myriad of clinical situations.
T419 79040-79263 Sentence denotes In doing so, we can achieve a significant reduction in the overwhelming health care costs and resources needed for respiratory exacerbations while improving the quality of life with a reduction in the mortality of patients.
T420 79265-79280 Sentence denotes Acknowledgments
T421 79281-79490 Sentence denotes NV was supported by the NIH (CTSA RRO25005 and RHL096931), Flight Attendant Medical Research Institute’s (FAMRI), Young Clinical Scientist Award (YCSA_082131) and CFF (CFF, R025-CR07 and VIJ07IO) grants to NV.
T422 79491-79642 Sentence denotes We thank Manish Bodas former postdoc in Vij’s lab for support with sections related to our laboratories prior work, related literature, and schematics.
T423 79644-79651 Sentence denotes Funding
T424 79652-79830 Sentence denotes The funders or institution had no role in design, decision to publish or preparation of the manuscript as its authors independent perspective based on prior and ongoing research.
T425 79832-79853 Sentence denotes Conflicts of Interest
T426 79854-79986 Sentence denotes NV is the lead inventor on patent targeting proteostasis mechanisms for rescuing CFTR protein-processing defect and CF lung disease.
T427 79987-80110 Sentence denotes NV is also the lead inventor of nano-based selective drug delivery and therapeutic targeting for obstructive lung diseases.
T428 80111-80304 Sentence denotes NV is a founder of PRECISION THERANOSTICS INC and VIJ BIOTECH that focuses on the bench-side translation of novel respiratory therapeutics and declares that he has no other competing interests.
T429 80306-80419 Sentence denotes Figure 1 Schematic representation showing mechanisms of respiratory exacerbations and lung disease pathogenesis.
T430 80420-80628 Sentence denotes The inflammatory/pathogenic receptors and cystic fibrosis transmembrane conductance regulator (CFTR) localized in lipid-raft membranes modulate immune response on viral or bacterial infection of airway cells.
T431 80629-80957 Sentence denotes In subjects with decreased expression of CFTR (chronic obstructive pulmonary disease (COPD)), misfolded-CFTR (ΔF508 CFTR, cystic fibrosis (CF)), or elderly subjects, increase in reactive oxygen species (ROS) activity within the cells inhibits the progression of endocytosed viruses and phagocytosed bacteria into phagolysosomes.
T432 80958-81163 Sentence denotes Furthermore, the ROS resulting from misfolded/ΔF508 CFTR or age-related changes causes ceramide accumulation within the plasma membrane, and increases TG2 expression, which causes crosslinking of Beclin-1.
T433 81164-81348 Sentence denotes This Beclin-1 crosslinking results in perinuclear aggresome body formation that further impairs autophagolysosomes formation to degrade autophagic cargo and clear infectious pathogens.
T434 81349-81474 Sentence denotes As a result of this impaired degradation or clearance, the immune response is further impaired leading to more ROS formation.
T435 81475-81570 Sentence denotes This ultimately develops into chronic lung disease with recurrent exacerbations and infections.
T436 81571-81731 Sentence denotes In case of viral infections such as SARS-CoV-2, the virus binds to the ACE2 receptor TMPRSS2 complex, to fuse with the host cell and gain entry for replication.
T437 81732-81957 Sentence denotes Autophagosome-lysosomal processing is a standard mechanism for clearance of viruses and other pathogen via xenophagy, which when impaired results in exacerbation, chronic inflammation, and pathogenesis of severe lung disease.
T438 81958-82136 Sentence denotes Figure 2 Autophagy-inducing compounds and their potential in treating inflammatory-oxidative stress responses, respiratory exacerbations and coronavirus disease-2019 (COVID-19).
T439 82137-82278 Sentence denotes The autophagy induction and other properties of various therapeutic compounds for treating pulmonary pathologies and exacerbations are shown.
T440 82279-82542 Sentence denotes The ability of these compounds to induce autophagy to rescue dysfunctional CFTR or clearance of misfolded proteins from aggresome bodies is a critical therapeutic property to consider when evaluating possible treatments for age-related and respiratory conditions.
T441 82543-82946 Sentence denotes In addition, anti-inflammatory, antioxidant, anti-biofilm, bactericidal, immune boosting, and mucolytic properties are further aspects of these compounds that have significant therapeutic potential in controlling chronic immune responses and exacerbations that trigger fatal lung conditions such as COPD, CF, acute respiratory distress syndrome (ARDS), idiopathic pulmonary fibrosis (IPF), and COVID-19.