PMC:7561592 / 5736-6421 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7561592","sourcedb":"PMC","sourceid":"7561592","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7561592","text":"Recently, the FDA issued a draft guidance addressing the recommended approaches for determination of the suitability of the vehicles intended for co-administration of paediatric medicines (21). Guidance is given on vehicle selection, description of standardised in vitro methods for evaluating vehicle compatibility and suggestions on product labelling for communication of acceptability of vehicles (21). It is necessary to conduct these investigations in order to fully understand the impact of this practice on drug formulation behaviour and better guide healthcare practitioners, patients and carers regarding medicine co-administration with vehicles, in the paediatric population.","tracks":[]}