PMC:7558233 / 35677-36542 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7558233","sourcedb":"PMC","sourceid":"7558233","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7558233","text":"Several studies in China have observed disseminated intravascular coagulation (DIC) in most non-survivors [97], [98]. Significantly higher levels of D-dimer and fibrin degradation products, as well as a longer prothrombin time, suggested that coagulopathy might be associated with poor prognosis [99]. The dynamic changes in D-dimer levels correlated positively with the prognosis of COVID-19 [98]. Patients with a sepsis-induced coagulopathy score greater than or equal to 4, or a D-dimer level greater than six times the upper limit of normal, exhibited a lower mortality rate when receiving low molecular weight heparin for 7 d or longer [100]. When given anticoagulant treatment, attention should be paid to avoid the development of diffuse alveolar hemorrhage, which is a life-threatening complication that may occur after the administration of warfarin 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