PMC:7556165 / 7805-8274 JSONTXT

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    LitCovid-sample-MedDRA

    {"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T41","span":{"begin":79,"end":82},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T42","span":{"begin":169,"end":172},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A41","pred":"meddra_id","subj":"T41","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"id":"A42","pred":"meddra_id","subj":"T42","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-sample-sentences

    {"project":"LitCovid-sample-sentences","denotations":[{"id":"T55","span":{"begin":0,"end":121},"obj":"Sentence"},{"id":"T56","span":{"begin":122,"end":179},"obj":"Sentence"},{"id":"T57","span":{"begin":180,"end":469},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-sample-Pubtator

    {"project":"LitCovid-sample-Pubtator","denotations":[{"id":"260","span":{"begin":0,"end":4},"obj":"Gene"},{"id":"261","span":{"begin":79,"end":82},"obj":"Gene"},{"id":"262","span":{"begin":138,"end":142},"obj":"Gene"},{"id":"263","span":{"begin":169,"end":172},"obj":"Gene"},{"id":"264","span":{"begin":184,"end":188},"obj":"Gene"},{"id":"265","span":{"begin":258,"end":262},"obj":"Gene"},{"id":"266","span":{"begin":363,"end":375},"obj":"Disease"},{"id":"267","span":{"begin":380,"end":402},"obj":"Disease"}],"attributes":[{"id":"A266","pred":"pubann:denotes","subj":"266","obj":"MESH:D006973"},{"id":"A263","pred":"pubann:denotes","subj":"263","obj":"Gene:1636"},{"id":"A261","pred":"pubann:denotes","subj":"261","obj":"Gene:1636"},{"id":"A262","pred":"pubann:denotes","subj":"262","obj":"Gene:59272"},{"id":"A264","pred":"pubann:denotes","subj":"264","obj":"Gene:59272"},{"id":"A260","pred":"pubann:denotes","subj":"260","obj":"Gene:59272"},{"id":"A265","pred":"pubann:denotes","subj":"265","obj":"Gene:59272"},{"id":"A267","pred":"pubann:denotes","subj":"267","obj":"MESH:D002318"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-sample-UniProt

    {"project":"LitCovid-sample-UniProt","denotations":[{"id":"T1247","span":{"begin":0,"end":4},"obj":"Protein"},{"id":"T1248","span":{"begin":79,"end":82},"obj":"Protein"},{"id":"T1273","span":{"begin":138,"end":142},"obj":"Protein"},{"id":"T1274","span":{"begin":169,"end":172},"obj":"Protein"},{"id":"T1299","span":{"begin":184,"end":188},"obj":"Protein"},{"id":"T1300","span":{"begin":258,"end":262},"obj":"Protein"}],"attributes":[{"id":"A1247","pred":"uniprot_id","subj":"T1247","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1248","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q9GLN7"},{"id":"A1249","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q9GLN6"},{"id":"A1250","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q9EQM9"},{"id":"A1251","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q8CFN1"},{"id":"A1252","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q7TMC6"},{"id":"A1253","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q7M4L4"},{"id":"A1254","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q6GTS2"},{"id":"A1255","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q59GY8"},{"id":"A1256","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q53YX9"},{"id":"A1257","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q50JE5"},{"id":"A1258","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q10751"},{"id":"A1259","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q0GA41"},{"id":"A1260","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/P47820"},{"id":"A1261","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/P22968"},{"id":"A1262","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/P22967"},{"id":"A1263","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/P22966"},{"id":"A1264","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/P12822"},{"id":"A1265","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/P12821"},{"id":"A1266","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/P12820"},{"id":"A1267","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/P09470"},{"id":"A1268","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/O02852"},{"id":"A1269","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/E7EU16"},{"id":"A1270","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/B4DXI3"},{"id":"A1271","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/B0LPF0"},{"id":"A1272","pred":"uniprot_id","subj":"T1248","obj":"https://www.uniprot.org/uniprot/Q9VJV3"},{"id":"A1273","pred":"uniprot_id","subj":"T1273","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1274","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q9GLN7"},{"id":"A1275","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q9GLN6"},{"id":"A1276","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q9EQM9"},{"id":"A1277","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q8CFN1"},{"id":"A1278","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q7TMC6"},{"id":"A1279","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q7M4L4"},{"id":"A1280","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q6GTS2"},{"id":"A1281","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q59GY8"},{"id":"A1282","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q53YX9"},{"id":"A1283","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q50JE5"},{"id":"A1284","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q10751"},{"id":"A1285","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q0GA41"},{"id":"A1286","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/P47820"},{"id":"A1287","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/P22968"},{"id":"A1288","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/P22967"},{"id":"A1289","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/P22966"},{"id":"A1290","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/P12822"},{"id":"A1291","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/P12821"},{"id":"A1292","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/P12820"},{"id":"A1293","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/P09470"},{"id":"A1294","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/O02852"},{"id":"A1295","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/E7EU16"},{"id":"A1296","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/B4DXI3"},{"id":"A1297","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/B0LPF0"},{"id":"A1298","pred":"uniprot_id","subj":"T1274","obj":"https://www.uniprot.org/uniprot/Q9VJV3"},{"id":"A1299","pred":"uniprot_id","subj":"T1299","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1300","pred":"uniprot_id","subj":"T1300","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-sample-PD-IDO

    {"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T23","span":{"begin":345,"end":359},"obj":"http://purl.obolibrary.org/obo/IDO_0000467"},{"id":"T24","span":{"begin":395,"end":402},"obj":"http://purl.obolibrary.org/obo/OGMS_0000031"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-sample-PD-FMA

    {"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T29","span":{"begin":16,"end":20},"obj":"Body_part"},{"id":"T30","span":{"begin":45,"end":55},"obj":"Body_part"},{"id":"T31","span":{"begin":83,"end":87},"obj":"Body_part"},{"id":"T32","span":{"begin":107,"end":117},"obj":"Body_part"},{"id":"T33","span":{"begin":189,"end":193},"obj":"Body_part"}],"attributes":[{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma67093"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma67093"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma74402"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-sample-PD-MONDO

    {"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T42","span":{"begin":363,"end":402},"obj":"Disease"}],"attributes":[{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0001302"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-sample-PD-HP

    {"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T12","span":{"begin":363,"end":375},"obj":"Phenotype"},{"id":"T13","span":{"begin":380,"end":402},"obj":"Phenotype"}],"attributes":[{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0001626"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0000822"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T12","span":{"begin":363,"end":375},"obj":"Phenotype"},{"id":"T13","span":{"begin":380,"end":402},"obj":"Phenotype"}],"attributes":[{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0001626"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"260","span":{"begin":0,"end":4},"obj":"Gene"},{"id":"261","span":{"begin":79,"end":82},"obj":"Gene"},{"id":"262","span":{"begin":138,"end":142},"obj":"Gene"},{"id":"263","span":{"begin":169,"end":172},"obj":"Gene"},{"id":"264","span":{"begin":184,"end":188},"obj":"Gene"},{"id":"265","span":{"begin":258,"end":262},"obj":"Gene"},{"id":"266","span":{"begin":363,"end":375},"obj":"Disease"},{"id":"267","span":{"begin":380,"end":402},"obj":"Disease"}],"attributes":[{"id":"A260","pred":"tao:has_database_id","subj":"260","obj":"Gene:59272"},{"id":"A261","pred":"tao:has_database_id","subj":"261","obj":"Gene:1636"},{"id":"A262","pred":"tao:has_database_id","subj":"262","obj":"Gene:59272"},{"id":"A263","pred":"tao:has_database_id","subj":"263","obj":"Gene:1636"},{"id":"A264","pred":"tao:has_database_id","subj":"264","obj":"Gene:59272"},{"id":"A265","pred":"tao:has_database_id","subj":"265","obj":"Gene:59272"},{"id":"A266","pred":"tao:has_database_id","subj":"266","obj":"MESH:D006973"},{"id":"A267","pred":"tao:has_database_id","subj":"267","obj":"MESH:D002318"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T55","span":{"begin":0,"end":121},"obj":"Sentence"},{"id":"T56","span":{"begin":122,"end":179},"obj":"Sentence"},{"id":"T57","span":{"begin":180,"end":469},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ACE2 is a 40 kb gene and it is positioned on chromosome Xp22, differently from ACE gene that is located on chromosome 17. The 18 exons of ACE2 are remarkably similar to ACE exons. The ACE2 gene depicts a large polymorphism and several novel polymorphisms of ACE2, with specific geographical distribution, have been described and associated with susceptibility to hypertension and cardiovascular disease (Burrell et al., 2013; Patel et al., 2014; Pinheiro et al., 2019)."}