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PMC:7556165 / 76649-77338 JSONTXT

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LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T208 138-151 Chemical denotes macromolecule http://purl.obolibrary.org/obo/CHEBI_33839

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T456 0-123 Sentence denotes From the structural point of view ACE2 is closely related to ACE, and its discovery was a by-product of ACE investigations.
T457 124-238 Sentence denotes However, this macromolecule has soon showed peculiar functional properties and has attracted increasing attention.
T458 239-490 Sentence denotes The expression of ACE2 in the heart, kidney and vascular system pointed to a role in the regulation of blood pressure and cardiovascular homeostasis, possibly as a counterbalance to ACE activation, but this hypothesis now appears to be too simplistic.
T459 491-689 Sentence denotes Additional functions of ACE2 are strongly suggested by its capability to modulate cytokine metabolism and the inflammatory reaction, as well as by its remarkable expression in the respiratory tract.

LitCovid-sample-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T171 269-274 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T172 276-282 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T173 287-302 Body_part denotes vascular system http://purl.obolibrary.org/obo/UBERON_0007798
T174 342-347 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T175 671-688 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
2135 34-38 Gene denotes ACE2 Gene:59272
2136 61-64 Gene denotes ACE Gene:1636
2137 104-107 Gene denotes ACE Gene:1636
2138 257-261 Gene denotes ACE2 Gene:59272
2139 421-424 Gene denotes ACE Gene:1636
2140 515-519 Gene denotes ACE2 Gene:59272
2141 361-387 Disease denotes cardiovascular homeostasis MESH:D002318

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T6565 34-38 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T6566 61-64 Protein denotes ACE https://www.uniprot.org/uniprot/Q9GLN7|https://www.uniprot.org/uniprot/Q9GLN6|https://www.uniprot.org/uniprot/Q9EQM9|https://www.uniprot.org/uniprot/Q8CFN1|https://www.uniprot.org/uniprot/Q7TMC6|https://www.uniprot.org/uniprot/Q7M4L4|https://www.uniprot.org/uniprot/Q6GTS2|https://www.uniprot.org/uniprot/Q59GY8|https://www.uniprot.org/uniprot/Q53YX9|https://www.uniprot.org/uniprot/Q50JE5|https://www.uniprot.org/uniprot/Q10751|https://www.uniprot.org/uniprot/Q0GA41|https://www.uniprot.org/uniprot/P47820|https://www.uniprot.org/uniprot/P22968|https://www.uniprot.org/uniprot/P22967|https://www.uniprot.org/uniprot/P22966|https://www.uniprot.org/uniprot/P12822|https://www.uniprot.org/uniprot/P12821|https://www.uniprot.org/uniprot/P12820|https://www.uniprot.org/uniprot/P09470|https://www.uniprot.org/uniprot/O02852|https://www.uniprot.org/uniprot/E7EU16|https://www.uniprot.org/uniprot/B4DXI3|https://www.uniprot.org/uniprot/B0LPF0|https://www.uniprot.org/uniprot/Q9VJV3
T6591 104-107 Protein denotes ACE https://www.uniprot.org/uniprot/Q9GLN7|https://www.uniprot.org/uniprot/Q9GLN6|https://www.uniprot.org/uniprot/Q9EQM9|https://www.uniprot.org/uniprot/Q8CFN1|https://www.uniprot.org/uniprot/Q7TMC6|https://www.uniprot.org/uniprot/Q7M4L4|https://www.uniprot.org/uniprot/Q6GTS2|https://www.uniprot.org/uniprot/Q59GY8|https://www.uniprot.org/uniprot/Q53YX9|https://www.uniprot.org/uniprot/Q50JE5|https://www.uniprot.org/uniprot/Q10751|https://www.uniprot.org/uniprot/Q0GA41|https://www.uniprot.org/uniprot/P47820|https://www.uniprot.org/uniprot/P22968|https://www.uniprot.org/uniprot/P22967|https://www.uniprot.org/uniprot/P22966|https://www.uniprot.org/uniprot/P12822|https://www.uniprot.org/uniprot/P12821|https://www.uniprot.org/uniprot/P12820|https://www.uniprot.org/uniprot/P09470|https://www.uniprot.org/uniprot/O02852|https://www.uniprot.org/uniprot/E7EU16|https://www.uniprot.org/uniprot/B4DXI3|https://www.uniprot.org/uniprot/B0LPF0|https://www.uniprot.org/uniprot/Q9VJV3
T6616 257-261 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T6617 421-424 Protein denotes ACE https://www.uniprot.org/uniprot/Q9GLN7|https://www.uniprot.org/uniprot/Q9GLN6|https://www.uniprot.org/uniprot/Q9EQM9|https://www.uniprot.org/uniprot/Q8CFN1|https://www.uniprot.org/uniprot/Q7TMC6|https://www.uniprot.org/uniprot/Q7M4L4|https://www.uniprot.org/uniprot/Q6GTS2|https://www.uniprot.org/uniprot/Q59GY8|https://www.uniprot.org/uniprot/Q53YX9|https://www.uniprot.org/uniprot/Q50JE5|https://www.uniprot.org/uniprot/Q10751|https://www.uniprot.org/uniprot/Q0GA41|https://www.uniprot.org/uniprot/P47820|https://www.uniprot.org/uniprot/P22968|https://www.uniprot.org/uniprot/P22967|https://www.uniprot.org/uniprot/P22966|https://www.uniprot.org/uniprot/P12822|https://www.uniprot.org/uniprot/P12821|https://www.uniprot.org/uniprot/P12820|https://www.uniprot.org/uniprot/P09470|https://www.uniprot.org/uniprot/O02852|https://www.uniprot.org/uniprot/E7EU16|https://www.uniprot.org/uniprot/B4DXI3|https://www.uniprot.org/uniprot/B0LPF0|https://www.uniprot.org/uniprot/Q9VJV3
T6642 515-519 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T312 93-100 http://purl.obolibrary.org/obo/IDO_0000607 denotes product
T313 177-187 http://purl.obolibrary.org/obo/BFO_0000034 denotes functional
T314 342-347 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T315 502-511 http://purl.obolibrary.org/obo/BFO_0000034 denotes functions

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T500 269-274 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T501 276-282 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T502 342-347 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T503 573-581 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T504 671-688 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130

LitCovid-sample-PD-MAT

Id Subject Object Predicate Lexical cue
T160 269-274 http://purl.obolibrary.org/obo/MAT_0000036 denotes heart
T161 276-282 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney
T162 342-347 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T163 342-347 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood

LitCovid-sample-PD-GO-BP-0

Id Subject Object Predicate Lexical cue
T184 328-356 http://purl.obolibrary.org/obo/GO_0008217 denotes regulation of blood pressure
T185 328-338 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T186 376-387 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T187 573-592 http://purl.obolibrary.org/obo/GO_0042107 denotes cytokine metabolism
T188 582-592 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism

LitCovid-sample-GO-BP

Id Subject Object Predicate Lexical cue
T190 328-356 http://purl.obolibrary.org/obo/GO_0008217 denotes regulation of blood pressure
T191 328-338 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T192 376-387 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T193 582-592 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2135 34-38 Gene denotes ACE2 Gene:59272
2136 61-64 Gene denotes ACE Gene:1636
2137 104-107 Gene denotes ACE Gene:1636
2138 257-261 Gene denotes ACE2 Gene:59272
2139 421-424 Gene denotes ACE Gene:1636
2140 515-519 Gene denotes ACE2 Gene:59272
2141 361-387 Disease denotes cardiovascular homeostasis MESH:D002318

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T456 0-123 Sentence denotes From the structural point of view ACE2 is closely related to ACE, and its discovery was a by-product of ACE investigations.
T457 124-238 Sentence denotes However, this macromolecule has soon showed peculiar functional properties and has attracted increasing attention.
T458 239-490 Sentence denotes The expression of ACE2 in the heart, kidney and vascular system pointed to a role in the regulation of blood pressure and cardiovascular homeostasis, possibly as a counterbalance to ACE activation, but this hypothesis now appears to be too simplistic.
T459 491-689 Sentence denotes Additional functions of ACE2 are strongly suggested by its capability to modulate cytokine metabolism and the inflammatory reaction, as well as by its remarkable expression in the respiratory tract.