PMC:7556165 / 71847-72120 JSONTXT

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T403","span":{"begin":158,"end":168},"obj":"Species"},{"id":"T404","span":{"begin":158,"end":162},"obj":"Species"},{"id":"T406","span":{"begin":265,"end":269},"obj":"Species"}],"attributes":[{"id":"A403","pred":"ncbi_taxonomy_id","subj":"T403","obj":"NCBItxid:2697049"},{"id":"A404","pred":"ncbi_taxonomy_id","subj":"T404","obj":"NCBItxid:694009"},{"id":"A406","pred":"ncbi_taxonomy_id","subj":"T406","obj":"NCBItxid:694009"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T424","span":{"begin":44,"end":205},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T152","span":{"begin":3,"end":9},"obj":"Body_part"}],"attributes":[{"id":"A152","pred":"uberon_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1961","span":{"begin":96,"end":101},"obj":"Gene"},{"id":"1962","span":{"begin":249,"end":253},"obj":"Gene"},{"id":"1969","span":{"begin":158,"end":168},"obj":"Species"}],"attributes":[{"id":"A1961","pred":"pubann:denotes","subj":"1961","obj":"Gene:59272"},{"id":"A1962","pred":"pubann:denotes","subj":"1962","obj":"Gene:59272"},{"id":"A1969","pred":"pubann:denotes","subj":"1969","obj":"Tax:2697049"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T6234","span":{"begin":169,"end":172},"obj":"Protein"},{"id":"T6243","span":{"begin":249,"end":253},"obj":"Protein"}],"attributes":[{"id":"A6234","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/Q63492"},{"id":"A6235","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/Q63491"},{"id":"A6236","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/Q62815"},{"id":"A6237","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/Q62691"},{"id":"A6238","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/Q01542"},{"id":"A6239","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/P27732"},{"id":"A6240","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/O09024"},{"id":"A6241","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/O09023"},{"id":"A6242","pred":"uniprot_id","subj":"T6234","obj":"https://www.uniprot.org/uniprot/O09022"},{"id":"A6243","pred":"uniprot_id","subj":"T6243","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T293","span":{"begin":189,"end":193},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T461","span":{"begin":3,"end":9},"obj":"Body_part"},{"id":"T462","span":{"begin":189,"end":193},"obj":"Body_part"}],"attributes":[{"id":"A461","pred":"fma_id","subj":"T461","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A462","pred":"fma_id","subj":"T462","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T425","span":{"begin":158,"end":168},"obj":"Disease"},{"id":"T426","span":{"begin":158,"end":162},"obj":"Disease"},{"id":"T428","span":{"begin":265,"end":269},"obj":"Disease"}],"attributes":[{"id":"A425","pred":"mondo_id","subj":"T425","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A426","pred":"mondo_id","subj":"T426","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A428","pred":"mondo_id","subj":"T428","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T140","span":{"begin":3,"end":9},"obj":"http://purl.obolibrary.org/obo/MAT_0000119"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1961","span":{"begin":96,"end":101},"obj":"Gene"},{"id":"1962","span":{"begin":249,"end":253},"obj":"Gene"},{"id":"1969","span":{"begin":158,"end":168},"obj":"Species"}],"attributes":[{"id":"A1961","pred":"tao:has_database_id","subj":"1961","obj":"Gene:59272"},{"id":"A1962","pred":"tao:has_database_id","subj":"1962","obj":"Gene:59272"},{"id":"A1969","pred":"tao:has_database_id","subj":"1969","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}

{"project":"LitCovid-sentences","denotations":[{"id":"T424","span":{"begin":44,"end":205},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"an kidney organoids (Monteil et al., 2020). In this context, Procko (2020) was able to engineer hACE2 sequences to obtain soluble receptors able to sequester SARS-CoV-2 RBD and inhibit its cell attachment. Remarkably, combinatorial mutants enhanced ACE2 binding to SARS-CoV"}