PMC:7556165 / 66090-66406 JSONTXT

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    LitCovid-sample-CHEBI

    {"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T180","span":{"begin":110,"end":117},"obj":"Chemical"},{"id":"T181","span":{"begin":118,"end":127},"obj":"Chemical"},{"id":"T182","span":{"begin":128,"end":135},"obj":"Chemical"},{"id":"T184","span":{"begin":172,"end":183},"obj":"Chemical"}],"attributes":[{"id":"A180","pred":"chebi_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/CHEBI_8116"},{"id":"A181","pred":"chebi_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/CHEBI_30807"},{"id":"A182","pred":"chebi_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/CHEBI_30089"},{"id":"A183","pred":"chebi_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/CHEBI_47622"},{"id":"A184","pred":"chebi_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/CHEBI_15841"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sample-PD-NCBITaxon

    {"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T369","span":{"begin":21,"end":26},"obj":"Species"},{"id":"T370","span":{"begin":70,"end":75},"obj":"Species"}],"attributes":[{"id":"A369","pred":"ncbi_taxonomy_id","subj":"T369","obj":"NCBItxid:9606"},{"id":"A370","pred":"ncbi_taxonomy_id","subj":"T370","obj":"NCBItxid:9606"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sample-sentences

    {"project":"LitCovid-sample-sentences","denotations":[{"id":"T392","span":{"begin":0,"end":316},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sample-PD-UBERON

    {"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T146","span":{"begin":37,"end":43},"obj":"Body_part"}],"attributes":[{"id":"A146","pred":"uberon_id","subj":"T146","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sample-Pubtator

    {"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1809","span":{"begin":76,"end":80},"obj":"Gene"},{"id":"1810","span":{"begin":311,"end":315},"obj":"Gene"},{"id":"1812","span":{"begin":21,"end":26},"obj":"Species"},{"id":"1813","span":{"begin":70,"end":75},"obj":"Species"},{"id":"1815","span":{"begin":110,"end":135},"obj":"Chemical"},{"id":"1817","span":{"begin":27,"end":43},"obj":"Disease"},{"id":"1818","span":{"begin":51,"end":57},"obj":"CellLine"},{"id":"1819","span":{"begin":82,"end":90},"obj":"CellLine"}],"attributes":[{"id":"A1810","pred":"pubann:denotes","subj":"1810","obj":"Gene:59272"},{"id":"A1819","pred":"pubann:denotes","subj":"1819","obj":"CVCL:L310"},{"id":"A1813","pred":"pubann:denotes","subj":"1813","obj":"Tax:9606"},{"id":"A1812","pred":"pubann:denotes","subj":"1812","obj":"Tax:9606"},{"id":"A1818","pred":"pubann:denotes","subj":"1818","obj":"CVCL:0045"},{"id":"A1815","pred":"pubann:denotes","subj":"1815","obj":"MESH:D013755"},{"id":"A1817","pred":"pubann:denotes","subj":"1817","obj":"MESH:D007674"},{"id":"A1809","pred":"pubann:denotes","subj":"1809","obj":"Gene:59272"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sample-UniProt

    {"project":"LitCovid-sample-UniProt","denotations":[{"id":"T6085","span":{"begin":27,"end":36},"obj":"Protein"},{"id":"T6086","span":{"begin":76,"end":80},"obj":"Protein"},{"id":"T6087","span":{"begin":82,"end":85},"obj":"Protein"},{"id":"T6090","span":{"begin":86,"end":90},"obj":"Protein"},{"id":"T6091","span":{"begin":311,"end":315},"obj":"Protein"}],"attributes":[{"id":"A6085","pred":"uniprot_id","subj":"T6085","obj":"https://www.uniprot.org/uniprot/P02301"},{"id":"A6086","pred":"uniprot_id","subj":"T6086","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A6087","pred":"uniprot_id","subj":"T6087","obj":"https://www.uniprot.org/uniprot/Q9H2V4"},{"id":"A6088","pred":"uniprot_id","subj":"T6087","obj":"https://www.uniprot.org/uniprot/Q9H2V3"},{"id":"A6089","pred":"uniprot_id","subj":"T6087","obj":"https://www.uniprot.org/uniprot/P29320"},{"id":"A6090","pred":"uniprot_id","subj":"T6090","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A6091","pred":"uniprot_id","subj":"T6091","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sample-PD-IDO

    {"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T263","span":{"begin":44,"end":49},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T264","span":{"begin":156,"end":166},"obj":"http://purl.obolibrary.org/obo/IDO_0000607"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sample-PD-FMA

    {"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T440","span":{"begin":37,"end":43},"obj":"Body_part"},{"id":"T441","span":{"begin":44,"end":49},"obj":"Body_part"}],"attributes":[{"id":"A440","pred":"fma_id","subj":"T440","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A441","pred":"fma_id","subj":"T441","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sample-PD-MAT

    {"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T133","span":{"begin":37,"end":43},"obj":"http://purl.obolibrary.org/obo/MAT_0000119"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"1809","span":{"begin":76,"end":80},"obj":"Gene"},{"id":"1810","span":{"begin":311,"end":315},"obj":"Gene"},{"id":"1812","span":{"begin":21,"end":26},"obj":"Species"},{"id":"1813","span":{"begin":70,"end":75},"obj":"Species"},{"id":"1815","span":{"begin":110,"end":135},"obj":"Chemical"},{"id":"1817","span":{"begin":27,"end":43},"obj":"Disease"},{"id":"1818","span":{"begin":51,"end":57},"obj":"CellLine"},{"id":"1819","span":{"begin":82,"end":90},"obj":"CellLine"}],"attributes":[{"id":"A1809","pred":"tao:has_database_id","subj":"1809","obj":"Gene:59272"},{"id":"A1810","pred":"tao:has_database_id","subj":"1810","obj":"Gene:59272"},{"id":"A1812","pred":"tao:has_database_id","subj":"1812","obj":"Tax:9606"},{"id":"A1813","pred":"tao:has_database_id","subj":"1813","obj":"Tax:9606"},{"id":"A1815","pred":"tao:has_database_id","subj":"1815","obj":"MESH:D013755"},{"id":"A1817","pred":"tao:has_database_id","subj":"1817","obj":"MESH:D007674"},{"id":"A1818","pred":"tao:has_database_id","subj":"1818","obj":"CVCL:0045"},{"id":"A1819","pred":"tao:has_database_id","subj":"1819","obj":"CVCL:L310"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T392","span":{"begin":0,"end":316},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In their experiment, human embryonic kidney cells (HEK293) expressing human ACE2 (HEK-ACE2) were treated with phorbol myristate acetate stimulation and the production of a polypeptide of 105 kDa was demonstrated by western blot analysis, suggesting the occurrence of a proteolytic shedding in the ectodomain of ACE2."}