PMC:7556165 / 58547-58888 JSONTXT

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T357","span":{"begin":0,"end":341},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1612","span":{"begin":103,"end":107},"obj":"Gene"},{"id":"1613","span":{"begin":224,"end":228},"obj":"Gene"},{"id":"1616","span":{"begin":159,"end":168},"obj":"Disease"},{"id":"1617","span":{"begin":267,"end":287},"obj":"Disease"}],"attributes":[{"id":"A1612","pred":"pubann:denotes","subj":"1612","obj":"Gene:59272"},{"id":"A1613","pred":"pubann:denotes","subj":"1613","obj":"Gene:59272"},{"id":"A1616","pred":"pubann:denotes","subj":"1616","obj":"MESH:D007239"},{"id":"A1617","pred":"pubann:denotes","subj":"1617","obj":"MESH:D012128"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T5767","span":{"begin":103,"end":107},"obj":"Protein"},{"id":"T5768","span":{"begin":224,"end":228},"obj":"Protein"}],"attributes":[{"id":"A5767","pred":"uniprot_id","subj":"T5767","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A5768","pred":"uniprot_id","subj":"T5768","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T224","span":{"begin":143,"end":148},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T225","span":{"begin":159,"end":168},"obj":"http://purl.obolibrary.org/obo/IDO_0000586"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T337","span":{"begin":159,"end":168},"obj":"Disease"}],"attributes":[{"id":"A337","pred":"mondo_id","subj":"T337","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}

{"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T59","span":{"begin":267,"end":287},"obj":"Phenotype"}],"attributes":[{"id":"A59","pred":"hp_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/HP_0002098"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T62","span":{"begin":267,"end":287},"obj":"Phenotype"}],"attributes":[{"id":"A62","pred":"hp_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/HP_0002098"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1612","span":{"begin":103,"end":107},"obj":"Gene"},{"id":"1613","span":{"begin":224,"end":228},"obj":"Gene"},{"id":"1616","span":{"begin":159,"end":168},"obj":"Disease"},{"id":"1617","span":{"begin":267,"end":287},"obj":"Disease"}],"attributes":[{"id":"A1612","pred":"tao:has_database_id","subj":"1612","obj":"Gene:59272"},{"id":"A1613","pred":"tao:has_database_id","subj":"1613","obj":"Gene:59272"},{"id":"A1616","pred":"tao:has_database_id","subj":"1616","obj":"MESH:D007239"},{"id":"A1617","pred":"tao:has_database_id","subj":"1617","obj":"MESH:D012128"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T357","span":{"begin":0,"end":341},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"An interesting speculation which could reconcile the two position comes from the hypothesis that while ACE2 is for sure the entry door for the virus, once the infection has evolved, there is the subsequent downregulation of ACE2, responsible for the precipitating of respiratory distress, as showed also in animal models (Kuba et al., 2005)."}