PMC:7556165 / 57795-58406 JSONTXT

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T343","span":{"begin":486,"end":496},"obj":"Species"},{"id":"T344","span":{"begin":486,"end":490},"obj":"Species"}],"attributes":[{"id":"A343","pred":"ncbi_taxonomy_id","subj":"T343","obj":"NCBItxid:2697049"},{"id":"A344","pred":"ncbi_taxonomy_id","subj":"T344","obj":"NCBItxid:694009"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T353","span":{"begin":0,"end":225},"obj":"Sentence"},{"id":"T354","span":{"begin":226,"end":413},"obj":"Sentence"},{"id":"T355","span":{"begin":414,"end":611},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T142","span":{"begin":13,"end":17},"obj":"Body_part"}],"attributes":[{"id":"A142","pred":"uberon_id","subj":"T142","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1595","span":{"begin":209,"end":213},"obj":"Gene"},{"id":"1596","span":{"begin":268,"end":272},"obj":"Gene"},{"id":"1597","span":{"begin":275,"end":279},"obj":"Gene"},{"id":"1598","span":{"begin":426,"end":430},"obj":"Gene"},{"id":"1599","span":{"begin":486,"end":496},"obj":"Species"},{"id":"1600","span":{"begin":127,"end":142},"obj":"Disease"},{"id":"1601","span":{"begin":363,"end":375},"obj":"Disease"},{"id":"1602","span":{"begin":377,"end":399},"obj":"Disease"},{"id":"1603","span":{"begin":404,"end":412},"obj":"Disease"}],"attributes":[{"id":"A1595","pred":"pubann:denotes","subj":"1595","obj":"Gene:59272"},{"id":"A1596","pred":"pubann:denotes","subj":"1596","obj":"Gene:59272"},{"id":"A1597","pred":"pubann:denotes","subj":"1597","obj":"Gene:59272"},{"id":"A1598","pred":"pubann:denotes","subj":"1598","obj":"Gene:59272"},{"id":"A1599","pred":"pubann:denotes","subj":"1599","obj":"Tax:2697049"},{"id":"A1600","pred":"pubann:denotes","subj":"1600","obj":"MESH:D001102"},{"id":"A1601","pred":"pubann:denotes","subj":"1601","obj":"MESH:D006973"},{"id":"A1602","pred":"pubann:denotes","subj":"1602","obj":"MESH:D002318"},{"id":"A1603","pred":"pubann:denotes","subj":"1603","obj":"MESH:D003920"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T5762","span":{"begin":209,"end":213},"obj":"Protein"},{"id":"T5763","span":{"begin":268,"end":272},"obj":"Protein"},{"id":"T5764","span":{"begin":275,"end":279},"obj":"Protein"},{"id":"T5765","span":{"begin":426,"end":430},"obj":"Protein"}],"attributes":[{"id":"A5762","pred":"uniprot_id","subj":"T5762","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A5763","pred":"uniprot_id","subj":"T5763","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A5764","pred":"uniprot_id","subj":"T5764","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A5765","pred":"uniprot_id","subj":"T5765","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T219","span":{"begin":133,"end":142},"obj":"http://purl.obolibrary.org/obo/IDO_0000586"},{"id":"T220","span":{"begin":147,"end":154},"obj":"http://purl.obolibrary.org/obo/OGMS_0000031"},{"id":"T221","span":{"begin":392,"end":399},"obj":"http://purl.obolibrary.org/obo/OGMS_0000031"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T399","span":{"begin":13,"end":17},"obj":"Body_part"}],"attributes":[{"id":"A399","pred":"fma_id","subj":"T399","obj":"http://purl.org/sig/ont/fma/fma9712"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T329","span":{"begin":127,"end":142},"obj":"Disease"},{"id":"T330","span":{"begin":363,"end":399},"obj":"Disease"},{"id":"T331","span":{"begin":404,"end":412},"obj":"Disease"},{"id":"T332","span":{"begin":486,"end":496},"obj":"Disease"},{"id":"T333","span":{"begin":486,"end":490},"obj":"Disease"}],"attributes":[{"id":"A329","pred":"mondo_id","subj":"T329","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A330","pred":"mondo_id","subj":"T330","obj":"http://purl.obolibrary.org/obo/MONDO_0001302"},{"id":"A331","pred":"mondo_id","subj":"T331","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A332","pred":"mondo_id","subj":"T332","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A333","pred":"mondo_id","subj":"T333","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T130","span":{"begin":13,"end":17},"obj":"http://purl.obolibrary.org/obo/MAT_0000091"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T105","span":{"begin":127,"end":142},"obj":"http://purl.obolibrary.org/obo/GO_0016032"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T57","span":{"begin":363,"end":375},"obj":"Phenotype"},{"id":"T58","span":{"begin":377,"end":399},"obj":"Phenotype"}],"attributes":[{"id":"A57","pred":"hp_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A58","pred":"hp_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/HP_0001626"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T107","span":{"begin":127,"end":142},"obj":"http://purl.obolibrary.org/obo/GO_0016032"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T60","span":{"begin":363,"end":375},"obj":"Phenotype"},{"id":"T61","span":{"begin":377,"end":399},"obj":"Phenotype"}],"attributes":[{"id":"A60","pred":"hp_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A61","pred":"hp_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/HP_0001626"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1595","span":{"begin":209,"end":213},"obj":"Gene"},{"id":"1596","span":{"begin":268,"end":272},"obj":"Gene"},{"id":"1597","span":{"begin":275,"end":279},"obj":"Gene"},{"id":"1598","span":{"begin":426,"end":430},"obj":"Gene"},{"id":"1599","span":{"begin":486,"end":496},"obj":"Species"},{"id":"1600","span":{"begin":127,"end":142},"obj":"Disease"},{"id":"1601","span":{"begin":363,"end":375},"obj":"Disease"},{"id":"1602","span":{"begin":377,"end":399},"obj":"Disease"},{"id":"1603","span":{"begin":404,"end":412},"obj":"Disease"}],"attributes":[{"id":"A1595","pred":"tao:has_database_id","subj":"1595","obj":"Gene:59272"},{"id":"A1596","pred":"tao:has_database_id","subj":"1596","obj":"Gene:59272"},{"id":"A1597","pred":"tao:has_database_id","subj":"1597","obj":"Gene:59272"},{"id":"A1598","pred":"tao:has_database_id","subj":"1598","obj":"Gene:59272"},{"id":"A1599","pred":"tao:has_database_id","subj":"1599","obj":"Tax:2697049"},{"id":"A1600","pred":"tao:has_database_id","subj":"1600","obj":"MESH:D001102"},{"id":"A1601","pred":"tao:has_database_id","subj":"1601","obj":"MESH:D006973"},{"id":"A1602","pred":"tao:has_database_id","subj":"1602","obj":"MESH:D002318"},{"id":"A1603","pred":"tao:has_database_id","subj":"1603","obj":"MESH:D003920"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}

{"project":"LitCovid-sentences","denotations":[{"id":"T353","span":{"begin":0,"end":225},"obj":"Sentence"},{"id":"T354","span":{"begin":226,"end":413},"obj":"Sentence"},{"id":"T355","span":{"begin":414,"end":611},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"On the other hand, a different viewpoint is based on the intriguing observation that several conditions increasing the risk of viral infection and disease severity are all characterized by a certain degree of ACE2 deficiency. As discussed above (section “Structure of ACE2”) ACE2 deficiency has been suggested to play a significant role in the pathophysiology of hypertension, cardiovascular disease and diabetes. The role of ACE2 expression in the panel of comorbidities correlated to SARS-CoV-2 is a matter of intense still unsolved debate, as brilliantly revised by Shyh et al. (2020) in a very recent paper."}