PMC:7556165 / 30825-31073 JSONTXT

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T71","span":{"begin":144,"end":147},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T72","span":{"begin":152,"end":166},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A71","pred":"meddra_id","subj":"T71","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"id":"A72","pred":"meddra_id","subj":"T72","obj":"http://purl.bioontology.org/ontology/MEDDRA/10002491"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T116","span":{"begin":152,"end":166},"obj":"Chemical"}],"attributes":[{"id":"A116","pred":"chebi_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/CHEBI_2719"},{"id":"A117","pred":"chebi_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/CHEBI_48432"},{"id":"A118","pred":"chebi_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/CHEBI_58506"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T125","span":{"begin":51,"end":54},"obj":"Body_part"},{"id":"T126","span":{"begin":97,"end":101},"obj":"Body_part"},{"id":"T127","span":{"begin":192,"end":196},"obj":"Body_part"}],"attributes":[{"id":"A125","pred":"uberon_id","subj":"T125","obj":"http://purl.obolibrary.org/obo/UBERON_0001460"},{"id":"A126","pred":"uberon_id","subj":"T126","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A127","pred":"uberon_id","subj":"T127","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"832","span":{"begin":46,"end":50},"obj":"Gene"},{"id":"833","span":{"begin":144,"end":147},"obj":"Gene"},{"id":"834","span":{"begin":152,"end":166},"obj":"Gene"},{"id":"836","span":{"begin":97,"end":109},"obj":"Disease"},{"id":"837","span":{"begin":186,"end":203},"obj":"Disease"},{"id":"838","span":{"begin":211,"end":229},"obj":"Disease"}],"attributes":[{"id":"A832","pred":"pubann:denotes","subj":"832","obj":"Gene:59272"},{"id":"A833","pred":"pubann:denotes","subj":"833","obj":"Gene:1636"},{"id":"A834","pred":"pubann:denotes","subj":"834","obj":"Gene:183"},{"id":"A836","pred":"pubann:denotes","subj":"836","obj":"MESH:D008171"},{"id":"A837","pred":"pubann:denotes","subj":"837","obj":"MESH:D055371"},{"id":"A838","pred":"pubann:denotes","subj":"838","obj":"MESH:D011658"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T2469","span":{"begin":46,"end":50},"obj":"Protein"},{"id":"T2470","span":{"begin":144,"end":147},"obj":"Protein"},{"id":"T2495","span":{"begin":152,"end":166},"obj":"Protein"}],"attributes":[{"id":"A2469","pred":"uniprot_id","subj":"T2469","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A2470","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q9GLN7"},{"id":"A2471","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q9GLN6"},{"id":"A2472","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q9EQM9"},{"id":"A2473","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q8CFN1"},{"id":"A2474","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q7TMC6"},{"id":"A2475","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q7M4L4"},{"id":"A2476","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q6GTS2"},{"id":"A2477","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q59GY8"},{"id":"A2478","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q53YX9"},{"id":"A2479","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q50JE5"},{"id":"A2480","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q10751"},{"id":"A2481","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q0GA41"},{"id":"A2482","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/P47820"},{"id":"A2483","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/P22968"},{"id":"A2484","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/P22967"},{"id":"A2485","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/P22966"},{"id":"A2486","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/P12822"},{"id":"A2487","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/P12821"},{"id":"A2488","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/P12820"},{"id":"A2489","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/P09470"},{"id":"A2490","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/O02852"},{"id":"A2491","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/E7EU16"},{"id":"A2492","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/B4DXI3"},{"id":"A2493","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/B0LPF0"},{"id":"A2494","pred":"uniprot_id","subj":"T2470","obj":"https://www.uniprot.org/uniprot/Q9VJV3"},{"id":"A2495","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/Q9TSZ0"},{"id":"A2496","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/Q9GLP7"},{"id":"A2497","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/Q9GLP6"},{"id":"A2498","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/Q9GLN8"},{"id":"A2499","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/Q96F91"},{"id":"A2500","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/Q16359"},{"id":"A2501","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/Q16358"},{"id":"A2502","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P67886"},{"id":"A2503","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P67885"},{"id":"A2504","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P20757"},{"id":"A2505","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P11859"},{"id":"A2506","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P01019"},{"id":"A2507","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P01018"},{"id":"A2508","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P01017"},{"id":"A2509","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P01016"},{"id":"A2510","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/P01015"},{"id":"A2511","pred":"uniprot_id","subj":"T2495","obj":"https://www.uniprot.org/uniprot/A0A3Q1LGY9"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T84","span":{"begin":6,"end":11},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T85","span":{"begin":102,"end":109},"obj":"http://purl.obolibrary.org/obo/OGMS_0000031"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T276","span":{"begin":6,"end":11},"obj":"Body_part"},{"id":"T277","span":{"begin":51,"end":54},"obj":"Body_part"},{"id":"T278","span":{"begin":97,"end":101},"obj":"Body_part"},{"id":"T279","span":{"begin":192,"end":196},"obj":"Body_part"}],"attributes":[{"id":"A276","pred":"fma_id","subj":"T276","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A277","pred":"fma_id","subj":"T277","obj":"http://purl.org/sig/ont/fma/fma24890"},{"id":"A278","pred":"fma_id","subj":"T278","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A279","pred":"fma_id","subj":"T279","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T68","span":{"begin":97,"end":109},"obj":"Disease"},{"id":"T69","span":{"begin":186,"end":203},"obj":"Disease"},{"id":"T71","span":{"begin":205,"end":208},"obj":"Disease"},{"id":"T72","span":{"begin":211,"end":229},"obj":"Disease"}],"attributes":[{"id":"A68","pred":"mondo_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/MONDO_0005275"},{"id":"A69","pred":"mondo_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A70","pred":"mondo_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/MONDO_0015796"},{"id":"A71","pred":"mondo_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A72","pred":"mondo_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/MONDO_0002771"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T116","span":{"begin":97,"end":101},"obj":"http://purl.obolibrary.org/obo/MAT_0000135"},{"id":"T117","span":{"begin":192,"end":196},"obj":"http://purl.obolibrary.org/obo/MAT_0000135"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T24","span":{"begin":97,"end":109},"obj":"Phenotype"},{"id":"T25","span":{"begin":211,"end":229},"obj":"Phenotype"}],"attributes":[{"id":"A24","pred":"hp_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/HP_0002088"},{"id":"A25","pred":"hp_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/HP_0002206"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T24","span":{"begin":97,"end":109},"obj":"Phenotype"},{"id":"T25","span":{"begin":186,"end":203},"obj":"Phenotype"},{"id":"T26","span":{"begin":205,"end":208},"obj":"Phenotype"},{"id":"T27","span":{"begin":211,"end":229},"obj":"Phenotype"}],"attributes":[{"id":"A24","pred":"hp_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/HP_0002088"},{"id":"A25","pred":"hp_id","subj":"T25","obj":"http://www.orpha.net/ORDO/Orphanet_178320"},{"id":"A26","pred":"hp_id","subj":"T26","obj":"http://www.orpha.net/ORDO/Orphanet_178320"},{"id":"A27","pred":"hp_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/HP_0002206"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}

{"project":"LitCovid-PubTator","denotations":[{"id":"832","span":{"begin":46,"end":50},"obj":"Gene"},{"id":"833","span":{"begin":144,"end":147},"obj":"Gene"},{"id":"834","span":{"begin":152,"end":166},"obj":"Gene"},{"id":"836","span":{"begin":97,"end":109},"obj":"Disease"},{"id":"837","span":{"begin":186,"end":203},"obj":"Disease"},{"id":"838","span":{"begin":211,"end":229},"obj":"Disease"}],"attributes":[{"id":"A832","pred":"tao:has_database_id","subj":"832","obj":"Gene:59272"},{"id":"A833","pred":"tao:has_database_id","subj":"833","obj":"Gene:1636"},{"id":"A834","pred":"tao:has_database_id","subj":"834","obj":"Gene:183"},{"id":"A836","pred":"tao:has_database_id","subj":"836","obj":"MESH:D008171"},{"id":"A837","pred":"tao:has_database_id","subj":"837","obj":"MESH:D055371"},{"id":"A838","pred":"tao:has_database_id","subj":"838","obj":"MESH:D011658"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"elial cells or VSMC). The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hyperte"}