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PMC:7556165 / 30712-31153 JSONTXT

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LitCovid-sample-MedDRA

Id Subject Object Predicate Lexical cue meddra_id
T71 257-260 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes ACE http://purl.bioontology.org/ontology/MEDDRA/10050289
T72 265-279 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes angiotensin II http://purl.bioontology.org/ontology/MEDDRA/10002491

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T116 265-279 Chemical denotes angiotensin II http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T191 0-134 Sentence denotes ACE2 is highly expressed in type I and II alveolar epithelial cells and in pulmonary small vessels (either endothelial cells or VSMC).
T192 135-441 Sentence denotes The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hypertension, and acute respiratory distress syndrome (ARDS) (Imai et al., 2005, 2010).

LitCovid-sample-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T124 91-98 Body_part denotes vessels http://purl.obolibrary.org/obo/UBERON_0000055
T125 164-167 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T126 210-214 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T127 305-309 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
831 0-4 Gene denotes ACE2 Gene:59272
832 159-163 Gene denotes ACE2 Gene:59272
833 257-260 Gene denotes ACE Gene:1636
834 265-279 Gene denotes angiotensin II Gene:183
835 75-90 Disease denotes pulmonary small MESH:D008171
836 210-222 Disease denotes lung disease MESH:D008171
837 299-316 Disease denotes acute lung injury MESH:D055371
838 324-342 Disease denotes pulmonary fibrosis MESH:D011658
839 344-366 Disease denotes pulmonary hypertension MESH:D006976
840 372-407 Disease denotes acute respiratory distress syndrome MESH:D012128
841 409-413 Disease denotes ARDS MESH:D012128

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T2468 0-4 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T2469 159-163 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T2470 257-260 Protein denotes ACE https://www.uniprot.org/uniprot/Q9GLN7|https://www.uniprot.org/uniprot/Q9GLN6|https://www.uniprot.org/uniprot/Q9EQM9|https://www.uniprot.org/uniprot/Q8CFN1|https://www.uniprot.org/uniprot/Q7TMC6|https://www.uniprot.org/uniprot/Q7M4L4|https://www.uniprot.org/uniprot/Q6GTS2|https://www.uniprot.org/uniprot/Q59GY8|https://www.uniprot.org/uniprot/Q53YX9|https://www.uniprot.org/uniprot/Q50JE5|https://www.uniprot.org/uniprot/Q10751|https://www.uniprot.org/uniprot/Q0GA41|https://www.uniprot.org/uniprot/P47820|https://www.uniprot.org/uniprot/P22968|https://www.uniprot.org/uniprot/P22967|https://www.uniprot.org/uniprot/P22966|https://www.uniprot.org/uniprot/P12822|https://www.uniprot.org/uniprot/P12821|https://www.uniprot.org/uniprot/P12820|https://www.uniprot.org/uniprot/P09470|https://www.uniprot.org/uniprot/O02852|https://www.uniprot.org/uniprot/E7EU16|https://www.uniprot.org/uniprot/B4DXI3|https://www.uniprot.org/uniprot/B0LPF0|https://www.uniprot.org/uniprot/Q9VJV3
T2495 265-279 Protein denotes angiotensin II https://www.uniprot.org/uniprot/Q9TSZ0|https://www.uniprot.org/uniprot/Q9GLP7|https://www.uniprot.org/uniprot/Q9GLP6|https://www.uniprot.org/uniprot/Q9GLN8|https://www.uniprot.org/uniprot/Q96F91|https://www.uniprot.org/uniprot/Q16359|https://www.uniprot.org/uniprot/Q16358|https://www.uniprot.org/uniprot/P67886|https://www.uniprot.org/uniprot/P67885|https://www.uniprot.org/uniprot/P20757|https://www.uniprot.org/uniprot/P11859|https://www.uniprot.org/uniprot/P01019|https://www.uniprot.org/uniprot/P01018|https://www.uniprot.org/uniprot/P01017|https://www.uniprot.org/uniprot/P01016|https://www.uniprot.org/uniprot/P01015|https://www.uniprot.org/uniprot/A0A3Q1LGY9

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T83 62-67 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T84 119-124 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T85 215-222 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T273 42-67 Body_part denotes alveolar epithelial cells http://purl.org/sig/ont/fma/fma62499
T274 62-67 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T275 107-124 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T276 119-124 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T277 164-167 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T278 210-214 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T279 305-309 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T68 210-222 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T69 299-316 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T71 318-321 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T72 324-342 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T73 344-366 Disease denotes pulmonary hypertension http://purl.obolibrary.org/obo/MONDO_0005149
T74 372-407 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T75 409-413 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502

LitCovid-sample-PD-MAT

Id Subject Object Predicate Lexical cue
T115 91-98 http://purl.obolibrary.org/obo/MAT_0000393 denotes vessels
T116 210-214 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T117 305-309 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

LitCovid-sample-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T24 210-222 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T25 324-342 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T26 354-366 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T27 378-398 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T24 210-222 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T25 299-316 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T26 318-321 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T27 324-342 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T28 354-366 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T29 378-398 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
831 0-4 Gene denotes ACE2 Gene:59272
832 159-163 Gene denotes ACE2 Gene:59272
833 257-260 Gene denotes ACE Gene:1636
834 265-279 Gene denotes angiotensin II Gene:183
835 75-90 Disease denotes pulmonary small MESH:D008171
836 210-222 Disease denotes lung disease MESH:D008171
837 299-316 Disease denotes acute lung injury MESH:D055371
838 324-342 Disease denotes pulmonary fibrosis MESH:D011658
839 344-366 Disease denotes pulmonary hypertension MESH:D006976
840 372-407 Disease denotes acute respiratory distress syndrome MESH:D012128
841 409-413 Disease denotes ARDS MESH:D012128

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T191 0-134 Sentence denotes ACE2 is highly expressed in type I and II alveolar epithelial cells and in pulmonary small vessels (either endothelial cells or VSMC).
T192 135-441 Sentence denotes The hypothesis that the ACE2 arm of the RAAS system could be of benefit in lung disease derives from the observation that ACE and angiotensin II are upregulated in acute lung injury (ALI), pulmonary fibrosis, pulmonary hypertension, and acute respiratory distress syndrome (ARDS) (Imai et al., 2005, 2010).