PMC:7556165 / 2041-2392 JSONTXT

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T6","span":{"begin":290,"end":304},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A6","pred":"meddra_id","subj":"T6","obj":"http://purl.bioontology.org/ontology/MEDDRA/10062026"}],"text":"nce accumulates, ACE2 appears a druggable target in the attempt to limit virus entry and replication. Strategies aimed at blocking ACE2 with antibodies, small molecules or peptides, or at neutralizing the virus by competitive binding with exogenously administered ACE2, are currently under investigations. In this review, we will present an overview o"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T5","span":{"begin":172,"end":180},"obj":"Chemical"}],"attributes":[{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"}],"text":"nce accumulates, ACE2 appears a druggable target in the attempt to limit virus entry and replication. Strategies aimed at blocking ACE2 with antibodies, small molecules or peptides, or at neutralizing the virus by competitive binding with exogenously administered ACE2, are currently under investigations. In this review, we will present an overview o"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T17","span":{"begin":102,"end":305},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"nce accumulates, ACE2 appears a druggable target in the attempt to limit virus entry and replication. Strategies aimed at blocking ACE2 with antibodies, small molecules or peptides, or at neutralizing the virus by competitive binding with exogenously administered ACE2, are currently under investigations. In this review, we will present an overview o"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"62","span":{"begin":17,"end":21},"obj":"Gene"},{"id":"63","span":{"begin":131,"end":135},"obj":"Gene"},{"id":"64","span":{"begin":264,"end":268},"obj":"Gene"}],"attributes":[{"id":"A62","pred":"pubann:denotes","subj":"62","obj":"Gene:59272"},{"id":"A63","pred":"pubann:denotes","subj":"63","obj":"Gene:59272"},{"id":"A64","pred":"pubann:denotes","subj":"64","obj":"Gene:59272"}],"text":"nce accumulates, ACE2 appears a druggable target in the attempt to limit virus entry and replication. Strategies aimed at blocking ACE2 with antibodies, small molecules or peptides, or at neutralizing the virus by competitive binding with exogenously administered ACE2, are currently under investigations. In this review, we will present an overview o"}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T138","span":{"begin":17,"end":21},"obj":"Protein"},{"id":"T139","span":{"begin":131,"end":135},"obj":"Protein"},{"id":"T140","span":{"begin":264,"end":268},"obj":"Protein"}],"attributes":[{"id":"A138","pred":"uniprot_id","subj":"T138","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A139","pred":"uniprot_id","subj":"T139","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A140","pred":"uniprot_id","subj":"T140","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"nce accumulates, ACE2 appears a druggable target in the attempt to limit virus entry and replication. Strategies aimed at blocking ACE2 with antibodies, small molecules or peptides, or at neutralizing the virus by competitive binding with exogenously administered ACE2, are currently under investigations. In this review, we will present an overview o"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T8","span":{"begin":73,"end":78},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T9","span":{"begin":89,"end":100},"obj":"http://purl.obolibrary.org/obo/IDO_0000608"},{"id":"T10","span":{"begin":205,"end":210},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"nce accumulates, ACE2 appears a druggable target in the attempt to limit virus entry and replication. Strategies aimed at blocking ACE2 with antibodies, small molecules or peptides, or at neutralizing the virus by competitive binding with exogenously administered ACE2, are currently under investigations. In this review, we will present an overview o"}

{"project":"LitCovid-PubTator","denotations":[{"id":"62","span":{"begin":17,"end":21},"obj":"Gene"},{"id":"63","span":{"begin":131,"end":135},"obj":"Gene"},{"id":"64","span":{"begin":264,"end":268},"obj":"Gene"}],"attributes":[{"id":"A62","pred":"tao:has_database_id","subj":"62","obj":"Gene:59272"},{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"Gene:59272"},{"id":"A64","pred":"tao:has_database_id","subj":"64","obj":"Gene:59272"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"nce accumulates, ACE2 appears a druggable target in the attempt to limit virus entry and replication. Strategies aimed at blocking ACE2 with antibodies, small molecules or peptides, or at neutralizing the virus by competitive binding with exogenously administered ACE2, are currently under investigations. In this review, we will present an overview o"}

{"project":"LitCovid-sentences","denotations":[{"id":"T17","span":{"begin":102,"end":305},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"nce accumulates, ACE2 appears a druggable target in the attempt to limit virus entry and replication. Strategies aimed at blocking ACE2 with antibodies, small molecules or peptides, or at neutralizing the virus by competitive binding with exogenously administered ACE2, are currently under investigations. In this review, we will present an overview o"}