PMC:7556165 / 16407-16687 JSONTXT

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T59","span":{"begin":174,"end":177},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A59","pred":"meddra_id","subj":"T59","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T28","span":{"begin":242,"end":247},"obj":"Body_part"}],"attributes":[{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"491","span":{"begin":169,"end":173},"obj":"Gene"},{"id":"489","span":{"begin":82,"end":86},"obj":"Gene"},{"id":"490","span":{"begin":115,"end":120},"obj":"Gene"},{"id":"492","span":{"begin":174,"end":177},"obj":"Gene"},{"id":"493","span":{"begin":215,"end":234},"obj":"Disease"}],"attributes":[{"id":"A489","pred":"pubann:denotes","subj":"489","obj":"Gene:6597"},{"id":"A490","pred":"pubann:denotes","subj":"490","obj":"Gene:2305"},{"id":"A491","pred":"pubann:denotes","subj":"491","obj":"Gene:59272"},{"id":"A492","pred":"pubann:denotes","subj":"492","obj":"Gene:1636"},{"id":"A493","pred":"pubann:denotes","subj":"493","obj":"MESH:D006332"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T1767","span":{"begin":169,"end":173},"obj":"Protein"},{"id":"T1768","span":{"begin":174,"end":177},"obj":"Protein"}],"attributes":[{"id":"A1767","pred":"uniprot_id","subj":"T1767","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1768","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q9GLN7"},{"id":"A1769","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q9GLN6"},{"id":"A1770","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q9EQM9"},{"id":"A1771","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q8CFN1"},{"id":"A1772","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q7TMC6"},{"id":"A1773","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q7M4L4"},{"id":"A1774","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q6GTS2"},{"id":"A1775","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q59GY8"},{"id":"A1776","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q53YX9"},{"id":"A1777","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q50JE5"},{"id":"A1778","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q10751"},{"id":"A1779","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q0GA41"},{"id":"A1780","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/P47820"},{"id":"A1781","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/P22968"},{"id":"A1782","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/P22967"},{"id":"A1783","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/P22966"},{"id":"A1784","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/P12822"},{"id":"A1785","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/P12821"},{"id":"A1786","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/P12820"},{"id":"A1787","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/P09470"},{"id":"A1788","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/O02852"},{"id":"A1789","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/E7EU16"},{"id":"A1790","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/B4DXI3"},{"id":"A1791","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/B0LPF0"},{"id":"A1792","pred":"uniprot_id","subj":"T1768","obj":"https://www.uniprot.org/uniprot/Q9VJV3"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T38","span":{"begin":65,"end":70},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T86","span":{"begin":53,"end":70},"obj":"Body_part"},{"id":"T87","span":{"begin":65,"end":70},"obj":"Body_part"},{"id":"T88","span":{"begin":87,"end":96},"obj":"Body_part"},{"id":"T89","span":{"begin":242,"end":247},"obj":"Body_part"}],"attributes":[{"id":"A86","pred":"fma_id","subj":"T86","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A87","pred":"fma_id","subj":"T87","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A88","pred":"fma_id","subj":"T88","obj":"http://purl.org/sig/ont/fma/fma67526"},{"id":"A89","pred":"fma_id","subj":"T89","obj":"http://purl.org/sig/ont/fma/fma7088"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T26","span":{"begin":242,"end":247},"obj":"http://purl.obolibrary.org/obo/MAT_0000036"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T43","span":{"begin":87,"end":106},"obj":"http://purl.obolibrary.org/obo/GO_0006338"},{"id":"T44","span":{"begin":121,"end":134},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T45","span":{"begin":257,"end":267},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T44","span":{"begin":87,"end":106},"obj":"http://purl.obolibrary.org/obo/GO_0006338"},{"id":"T45","span":{"begin":121,"end":141},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T46","span":{"begin":121,"end":134},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T47","span":{"begin":257,"end":267},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}

{"project":"LitCovid-PubTator","denotations":[{"id":"489","span":{"begin":82,"end":86},"obj":"Gene"},{"id":"490","span":{"begin":115,"end":120},"obj":"Gene"},{"id":"491","span":{"begin":169,"end":173},"obj":"Gene"},{"id":"492","span":{"begin":174,"end":177},"obj":"Gene"},{"id":"493","span":{"begin":215,"end":234},"obj":"Disease"}],"attributes":[{"id":"A489","pred":"tao:has_database_id","subj":"489","obj":"Gene:6597"},{"id":"A490","pred":"tao:has_database_id","subj":"490","obj":"Gene:2305"},{"id":"A491","pred":"tao:has_database_id","subj":"491","obj":"Gene:59272"},{"id":"A492","pred":"tao:has_database_id","subj":"492","obj":"Gene:1636"},{"id":"A493","pred":"tao:has_database_id","subj":"493","obj":"MESH:D006332"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"d that a subtle regulatory mechanism acts in cardiac endothelial cells, where the Brg1 chromatin remodeler and the FoxM1 transcription factor cooperate to determine the ACE2/ACE expression ratio, particularly under cardiac hypertrophy of the heart.\nFurther regulation occurs at th"}