PMC:7556165 / 14396-14611 JSONTXT

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T43","span":{"begin":189,"end":194},"obj":"Species"}],"attributes":[{"id":"A43","pred":"ncbi_taxonomy_id","subj":"T43","obj":"NCBItxid:9606"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"restored basal ACE2 levels. Chromatin immunoprecipitation sequencing (ChIP-seq) showed that EZH2 depletion induced H3K27me3 decrease, with concomitant H3K27ac increase, at ACE2 promoter in human ESCs (Li Y. et al., "}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"431","span":{"begin":15,"end":19},"obj":"Gene"},{"id":"432","span":{"begin":92,"end":96},"obj":"Gene"},{"id":"433","span":{"begin":172,"end":176},"obj":"Gene"},{"id":"437","span":{"begin":189,"end":194},"obj":"Species"}],"attributes":[{"id":"A431","pred":"pubann:denotes","subj":"431","obj":"Gene:59272"},{"id":"A432","pred":"pubann:denotes","subj":"432","obj":"Gene:2146"},{"id":"A433","pred":"pubann:denotes","subj":"433","obj":"Gene:59272"},{"id":"A437","pred":"pubann:denotes","subj":"437","obj":"Tax:9606"}],"text":"restored basal ACE2 levels. Chromatin immunoprecipitation sequencing (ChIP-seq) showed that EZH2 depletion induced H3K27me3 decrease, with concomitant H3K27ac increase, at ACE2 promoter in human ESCs (Li Y. et al., "}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T1701","span":{"begin":15,"end":19},"obj":"Protein"},{"id":"T1702","span":{"begin":172,"end":176},"obj":"Protein"}],"attributes":[{"id":"A1701","pred":"uniprot_id","subj":"T1701","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A1702","pred":"uniprot_id","subj":"T1702","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"restored basal ACE2 levels. Chromatin immunoprecipitation sequencing (ChIP-seq) showed that EZH2 depletion induced H3K27me3 decrease, with concomitant H3K27ac increase, at ACE2 promoter in human ESCs (Li Y. et al., "}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T72","span":{"begin":28,"end":37},"obj":"Body_part"}],"attributes":[{"id":"A72","pred":"fma_id","subj":"T72","obj":"http://purl.org/sig/ont/fma/fma67526"}],"text":"restored basal ACE2 levels. Chromatin immunoprecipitation sequencing (ChIP-seq) showed that EZH2 depletion induced H3K27me3 decrease, with concomitant H3K27ac increase, at ACE2 promoter in human ESCs (Li Y. et al., "}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T49","span":{"begin":195,"end":199},"obj":"Disease"}],"attributes":[{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0009989"}],"text":"restored basal ACE2 levels. Chromatin immunoprecipitation sequencing (ChIP-seq) showed that EZH2 depletion induced H3K27me3 decrease, with concomitant H3K27ac increase, at ACE2 promoter in human ESCs (Li Y. et al., "}

{"project":"LitCovid-PubTator","denotations":[{"id":"431","span":{"begin":15,"end":19},"obj":"Gene"},{"id":"432","span":{"begin":92,"end":96},"obj":"Gene"},{"id":"433","span":{"begin":172,"end":176},"obj":"Gene"},{"id":"437","span":{"begin":189,"end":194},"obj":"Species"}],"attributes":[{"id":"A431","pred":"tao:has_database_id","subj":"431","obj":"Gene:59272"},{"id":"A432","pred":"tao:has_database_id","subj":"432","obj":"Gene:2146"},{"id":"A433","pred":"tao:has_database_id","subj":"433","obj":"Gene:59272"},{"id":"A437","pred":"tao:has_database_id","subj":"437","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"restored basal ACE2 levels. Chromatin immunoprecipitation sequencing (ChIP-seq) showed that EZH2 depletion induced H3K27me3 decrease, with concomitant H3K27ac increase, at ACE2 promoter in human ESCs (Li Y. et al., "}