PMC:7554011 / 12391-13064 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7554011","sourcedb":"PMC","sourceid":"7554011","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7554011","text":"The effect of different administration scenarios on drug dissolution was investigated by varying the mode of the introduction of the formulation in the simulated gastric fluid in the dissolution vessel: direct administration of the formulation or administration of the formulation after mixing with drinks (formula and milk) or soft food (applesauce). These vehicles were selected based on their impact on the dissolution of montelukast (12) and/or to mimic the in vivo studies performed in infants (12,16,17,19). The composition and physicochemical properties of these vehicles, including pH, buffer capacity and viscosity, have been recently published and discussed (13).","tracks":[{"project":"2_test","denotations":[{"id":"33051713-16707408-26794","span":{"begin":503,"end":505},"obj":"16707408"},{"id":"33051713-18296556-26795","span":{"begin":506,"end":508},"obj":"18296556"},{"id":"33051713-15102869-26796","span":{"begin":509,"end":511},"obj":"15102869"}],"attributes":[{"subj":"33051713-16707408-26794","pred":"source","obj":"2_test"},{"subj":"33051713-18296556-26795","pred":"source","obj":"2_test"},{"subj":"33051713-15102869-26796","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#a9ec93","default":true}]}]}}