PMC:7553377 / 18600-20122 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7553377","sourcedb":"PMC","sourceid":"7553377","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7553377","text":"There were statistically significant differences between the two groups of patients in terms of WBC, neutrophil, lymphocyte, monocyte, and platelet counts that were obtained at hospital admission (p \u003c 0.05). ROC analysis was used to determine cut-off values of the laboratory parameters obtained at the time of the first chest CT to predict the changes in the lung CT scores. Patients with a WBC count \u003c 6 × 103/µL, neutrophil count \u003c 3.3 × 103/µL, lymphocyte count \u003c 1.7 × 103/µL, monocyte count \u003c 0.55 × 103/µL, and platelet count \u003c 230 × 103/µL, which were obtained correspondingly at the time of the first chest CT, were predicted to have elevated lung CT scores in the consecutive scan (Table 3).\nTable 3 Predictors at hospital admission for the progression of lung CT score\nParameter Cut-off valuea AUC 95% confidence interval Sensitivity (%) Specificity (%) PPV (%) NPV (%) Std. Error p\nLower Upper\nWBC count 6 0.850 0.651 1 85 85.7 94.4 66.7 0.102 0.007\nNeutrophil count 3.3 0.757 0.531 0.983 75 71.4 88.2 50 0.115 0.046\nLymphocyte count 1.7 0.843 0.654 1 90 71.4 90.5 83.3 0.096 0.008\nMonocyte count 0.55 0.757 0.510 1 70 57.1 82.4 40 0.126 0.046\nPlatelet count 230 0.929 0.813 1 95 85.7 95 85.7 0.059 0.001\naCut-off value is given as (× 103/µL). AUC area under curve, lymphocyte count (1–3.38 × 103/µL), monocyte count (0–0.8 × 103/µL), neutrophil count (2.02–7.46 × 103/µL), NPV negative predictive value, platelet count (150–450 × 103/µL), PPV positive predictive value, WBC white blood cells (4.5–11 × 103/µL)","divisions":[{"label":"label","span":{"begin":702,"end":709}},{"label":"caption","span":{"begin":710,"end":779}},{"label":"p","span":{"begin":710,"end":779}},{"label":"table","span":{"begin":780,"end":1216}},{"label":"tr","span":{"begin":780,"end":893}},{"label":"th","span":{"begin":780,"end":789}},{"label":"th","span":{"begin":790,"end":804}},{"label":"th","span":{"begin":805,"end":808}},{"label":"th","span":{"begin":809,"end":832}},{"label":"th","span":{"begin":833,"end":848}},{"label":"th","span":{"begin":849,"end":864}},{"label":"th","span":{"begin":865,"end":872}},{"label":"th","span":{"begin":873,"end":880}},{"label":"th","span":{"begin":881,"end":891}},{"label":"th","span":{"begin":892,"end":893}},{"label":"tr","span":{"begin":894,"end":905}},{"label":"th","span":{"begin":894,"end":899}},{"label":"th","span":{"begin":900,"end":905}},{"label":"tr","span":{"begin":906,"end":961}},{"label":"td","span":{"begin":906,"end":915}},{"label":"td","span":{"begin":916,"end":917}},{"label":"td","span":{"begin":918,"end":923}},{"label":"td","span":{"begin":924,"end":929}},{"label":"td","span":{"begin":930,"end":931}},{"label":"td","span":{"begin":932,"end":934}},{"label":"td","span":{"begin":935,"end":939}},{"label":"td","span":{"begin":940,"end":944}},{"label":"td","span":{"begin":945,"end":949}},{"label":"td","span":{"begin":950,"end":955}},{"label":"td","span":{"begin":956,"end":961}},{"label":"tr","span":{"begin":962,"end":1028}},{"label":"td","span":{"begin":962,"end":978}},{"label":"td","span":{"begin":979,"end":982}},{"label":"td","span":{"begin":983,"end":988}},{"label":"td","span":{"begin":989,"end":994}},{"label":"td","span":{"begin":995,"end":1000}},{"label":"td","span":{"begin":1001,"end":1003}},{"label":"td","span":{"begin":1004,"end":1008}},{"label":"td","span":{"begin":1009,"end":1013}},{"label":"td","span":{"begin":1014,"end":1016}},{"label":"td","span":{"begin":1017,"end":1022}},{"label":"td","span":{"begin":1023,"end":1028}},{"label":"tr","span":{"begin":1029,"end":1093}},{"label":"td","span":{"begin":1029,"end":1045}},{"label":"td","span":{"begin":1046,"end":1049}},{"label":"td","span":{"begin":1050,"end":1055}},{"label":"td","span":{"begin":1056,"end":1061}},{"label":"td","span":{"begin":1062,"end":1063}},{"label":"td","span":{"begin":1064,"end":1066}},{"label":"td","span":{"begin":1067,"end":1071}},{"label":"td","span":{"begin":1072,"end":1076}},{"label":"td","span":{"begin":1077,"end":1081}},{"label":"td","span":{"begin":1082,"end":1087}},{"label":"td","span":{"begin":1088,"end":1093}},{"label":"tr","span":{"begin":1094,"end":1155}},{"label":"td","span":{"begin":1094,"end":1108}},{"label":"td","span":{"begin":1109,"end":1113}},{"label":"td","span":{"begin":1114,"end":1119}},{"label":"td","span":{"begin":1120,"end":1125}},{"label":"td","span":{"begin":1126,"end":1127}},{"label":"td","span":{"begin":1128,"end":1130}},{"label":"td","span":{"begin":1131,"end":1135}},{"label":"td","span":{"begin":1136,"end":1140}},{"label":"td","span":{"begin":1141,"end":1143}},{"label":"td","span":{"begin":1144,"end":1149}},{"label":"td","span":{"begin":1150,"end":1155}},{"label":"tr","span":{"begin":1156,"end":1216}},{"label":"td","span":{"begin":1156,"end":1170}},{"label":"td","span":{"begin":1171,"end":1174}},{"label":"td","span":{"begin":1175,"end":1180}},{"label":"td","span":{"begin":1181,"end":1186}},{"label":"td","span":{"begin":1187,"end":1188}},{"label":"td","span":{"begin":1189,"end":1191}},{"label":"td","span":{"begin":1192,"end":1196}},{"label":"td","span":{"begin":1197,"end":1199}},{"label":"td","span":{"begin":1200,"end":1204}},{"label":"td","span":{"begin":1205,"end":1210}},{"label":"td","span":{"begin":1211,"end":1216}}],"tracks":[]}