PMC:7553147 / 35202-35853 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7553147","sourcedb":"PMC","sourceid":"7553147","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7553147","text":"An obvious way to increase the resolution of the moving parts of the spike is to reduce their mobility, as is the case, for instance, in the biochemical stabilization of Hsieh et al. (2020 ▸) and also in the formation of a complex with an antibody against NTD (Chi et al., 2020 ▸). On the other hand, the route towards a more complete analysis of the flexibility of the spike protein necessarily involves the analysis of data sets that are quite substantially larger than those being used in most current SARS-CoV-2 studies, so that all of the main axes of inter-image variability can be explored; this is work that is under development at the moment.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T68","span":{"begin":239,"end":247},"obj":"Body_part"},{"id":"T69","span":{"begin":295,"end":299},"obj":"Body_part"},{"id":"T70","span":{"begin":376,"end":383},"obj":"Body_part"}],"attributes":[{"id":"A68","pred":"fma_id","subj":"T68","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A69","pred":"fma_id","subj":"T69","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A70","pred":"fma_id","subj":"T70","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T11","span":{"begin":295,"end":299},"obj":"Body_part"}],"attributes":[{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"},{"subj":"T11","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T51","span":{"begin":256,"end":259},"obj":"Disease"},{"id":"T53","span":{"begin":505,"end":513},"obj":"Disease"}],"attributes":[{"id":"A51","pred":"mondo_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/MONDO_0008449"},{"id":"A52","pred":"mondo_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/MONDO_0018075"},{"id":"A53","pred":"mondo_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T254","span":{"begin":221,"end":222},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T255","span":{"begin":319,"end":320},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T254","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T255","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T8","span":{"begin":208,"end":217},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"attributes":[{"subj":"T8","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T238","span":{"begin":0,"end":281},"obj":"Sentence"},{"id":"T239","span":{"begin":282,"end":651},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T238","pred":"source","obj":"LitCovid-sentences"},{"subj":"T239","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"210","span":{"begin":69,"end":74},"obj":"Gene"},{"id":"211","span":{"begin":370,"end":375},"obj":"Gene"},{"id":"212","span":{"begin":505,"end":515},"obj":"Species"},{"id":"213","span":{"begin":170,"end":175},"obj":"Disease"}],"attributes":[{"id":"A210","pred":"tao:has_database_id","subj":"210","obj":"Gene:43740568"},{"id":"A211","pred":"tao:has_database_id","subj":"211","obj":"Gene:43740568"},{"id":"A212","pred":"tao:has_database_id","subj":"212","obj":"Tax:2697049"},{"subj":"210","pred":"source","obj":"LitCovid-PubTator"},{"subj":"211","pred":"source","obj":"LitCovid-PubTator"},{"subj":"212","pred":"source","obj":"LitCovid-PubTator"},{"subj":"213","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#9395ec","default":true},{"id":"LitCovid-PD-UBERON","color":"#afec93"},{"id":"LitCovid-PD-MONDO","color":"#ec93c9"},{"id":"LitCovid-PD-CLO","color":"#93e3ec"},{"id":"LitCovid-PD-GO-BP","color":"#ecda93"},{"id":"LitCovid-sentences","color":"#c093ec"},{"id":"LitCovid-PubTator","color":"#93eca6"}]}]}}