Id |
Subject |
Object |
Predicate |
Lexical cue |
T87 |
0-4 |
Sentence |
denotes |
2.4. |
T88 |
6-39 |
Sentence |
denotes |
Validation and quality analysis |
T89 |
40-285 |
Sentence |
denotes |
To judge the quality of our structural results, we concentrated here on three of the newest approaches: directional local resolution (Vilas et al., 2020 ▸), Q-score (Pintilie et al., 2020 ▸) and FSC-Q (Ramirez-Aportela, Maluenda et al., 2020 ▸). |
T90 |
286-541 |
Sentence |
denotes |
The first provides a measure of map quality, while the latter two focus on the relationship between the map and the structural model; in other words, how well the model is supported by the map density, without any other complementary piece of information. |
T91 |
542-601 |
Sentence |
denotes |
In terms of map-to-model validation, in Supplementary Figs. |
T92 |
602-766 |
Sentence |
denotes |
S3(a) and S3(b) we present Q-score and FSC-Q metrics, respectively, showing the agreement between the ensemble cryo-EM map and the structural model derived from it. |
T93 |
767-961 |
Sentence |
denotes |
In most areas the agreement is very good, with the exception of the receptor-binding domain (RBD) and substantial parts of the N-terminal domain (NTD), as expected from their higher flexibility. |