PMC:7546716 / 868-2160
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T16 | 2-6 | Body_part | denotes | axis | http://purl.org/sig/ont/fma/fma12520 |
T17 | 52-63 | Body_part | denotes | granulocyte | http://purl.org/sig/ont/fma/fma62854 |
T18 | 64-74 | Body_part | denotes | macrophage | http://purl.org/sig/ont/fma/fma63261 |
T19 | 114-119 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T20 | 250-252 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
T21 | 299-313 | Body_part | denotes | myofibroblasts | http://purl.org/sig/ont/fma/fma0326458 |
T22 | 464-466 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
T23 | 508-513 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T24 | 522-526 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T25 | 539-547 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T26 | 848-852 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T27 | 1141-1151 | Body_part | denotes | macrophage | http://purl.org/sig/ont/fma/fma63261 |
T28 | 1241-1250 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T3 | 848-852 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T8 | 197-207 | Disease | denotes | thromboses | http://purl.obolibrary.org/obo/MONDO_0000831 |
T9 | 240-248 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T10 | 268-286 | Disease | denotes | pulmonary fibrosis | http://purl.obolibrary.org/obo/MONDO_0002771 |
T11 | 636-644 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T12 | 656-703 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T13 | 656-689 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T14 | 705-713 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T15 | 848-860 | Disease | denotes | lung disease | http://purl.obolibrary.org/obo/MONDO_0005275 |
T16 | 877-885 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T17 | 924-932 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T18 | 952-964 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T19 | 983-1018 | Disease | denotes | acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
T20 | 989-1018 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
T21 | 1024-1036 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
T22 | 1075-1120 | Disease | denotes | secondary haemophagocytic lymphohistiocytosis | http://purl.obolibrary.org/obo/MONDO_0015542 |
T23 | 1141-1171 | Disease | denotes | macrophage activation syndrome | http://purl.obolibrary.org/obo/MONDO_0015545 |
T24 | 1173-1176 | Disease | denotes | MAS | http://purl.obolibrary.org/obo/MONDO_0015545 |
T25 | 1269-1272 | Disease | denotes | MAS | http://purl.obolibrary.org/obo/MONDO_0015545 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10 | 112-119 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T11 | 318-328 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T12 | 480-483 | http://purl.obolibrary.org/obo/CLO_0051025 | denotes | ST2 |
T13 | 506-513 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T14 | 522-526 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T15 | 848-852 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T16 | 848-852 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T17 | 1124-1129 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T18 | 1152-1162 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T19 | 1200-1207 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focused |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T9 | 128-137 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
T10 | 138-148 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
T11 | 250-252 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T13 | 464-466 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T15 | 804-813 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T2 | 268-286 | Phenotype | denotes | pulmonary fibrosis | http://purl.obolibrary.org/obo/HP_0002206 |
T3 | 848-860 | Phenotype | denotes | lung disease | http://purl.obolibrary.org/obo/HP_0002088 |
T4 | 989-1009 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
T5 | 1024-1036 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 318-351 | http://purl.obolibrary.org/obo/GO_0001837 | denotes | epithelial–mesenchymal transition |
T2 | 952-964 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T3 | 1141-1162 | http://purl.obolibrary.org/obo/GO_0042116 | denotes | macrophage activation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8 | 209-352 | Sentence | denotes | In patients who survive severe COVID-19, IL-33 might drive pulmonary fibrosis by inducing myofibroblasts and epithelial–mesenchymal transition. |
T9 | 353-556 | Sentence | denotes | We discuss the therapeutic implications of these hypothetical pathways, including use of therapies that target IL-33 (eg, anti-ST2), T helper 17-like γδ T cells, immune cell homing, and cytokine balance. |
T10 | 558-570 | Sentence | denotes | Introduction |
T11 | 571-746 | Sentence | denotes | Intensive efforts are underway to unravel the immunopathology of COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and to control the pandemic. |
T12 | 747-1178 | Sentence | denotes | Given the public health emergency, scarcity of effective antiviral therapies, and rapid evolution of lung disease associated with COVID-19, patients who are critically ill with COVID-19 and have exuberant inflammation, life-threatening acute respiratory distress syndrome, and coagulopathy, are basically treated as if they had secondary haemophagocytic lymphohistiocytosis or virus-associated macrophage activation syndrome (MAS). |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
28 | 52-100 | Gene | denotes | granulocyte–macrophage colony-stimulating factor | Gene:1437 |
29 | 250-255 | Gene | denotes | IL-33 | Gene:90865 |
30 | 464-469 | Gene | denotes | IL-33 | Gene:90865 |
31 | 480-483 | Gene | denotes | ST2 | Gene:6761 |
32 | 471-473 | Gene | denotes | eg | Gene:50512 |
34 | 212-220 | Species | denotes | patients | Tax:9606 |
40 | 240-248 | Disease | denotes | COVID-19 | MESH:C000657245 |
41 | 268-286 | Disease | denotes | pulmonary fibrosis | MESH:D011658 |
70 | 656-703 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
71 | 705-715 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
72 | 887-895 | Species | denotes | patients | Tax:9606 |
73 | 636-644 | Disease | denotes | COVID-19 | MESH:C000657245 |
74 | 848-860 | Disease | denotes | lung disease | MESH:D008171 |
75 | 877-885 | Disease | denotes | COVID-19 | MESH:C000657245 |
76 | 904-918 | Disease | denotes | critically ill | MESH:D016638 |
77 | 924-932 | Disease | denotes | COVID-19 | MESH:C000657245 |
78 | 952-964 | Disease | denotes | inflammation | MESH:D007249 |
79 | 983-1018 | Disease | denotes | acute respiratory distress syndrome | MESH:D012128 |
80 | 1024-1036 | Disease | denotes | coagulopathy | MESH:D001778 |
81 | 1075-1120 | Disease | denotes | secondary haemophagocytic lymphohistiocytosis | MESH:D060085 |
82 | 1141-1171 | Disease | denotes | macrophage activation syndrome | MESH:D055501 |