PMC:7546716 / 6467-7107 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T97","span":{"begin":19,"end":24},"obj":"Body_part"},{"id":"T98","span":{"begin":51,"end":55},"obj":"Body_part"},{"id":"T99","span":{"begin":158,"end":160},"obj":"Body_part"},{"id":"T100","span":{"begin":240,"end":242},"obj":"Body_part"},{"id":"T101","span":{"begin":264,"end":269},"obj":"Body_part"},{"id":"T102","span":{"begin":346,"end":348},"obj":"Body_part"},{"id":"T103","span":{"begin":409,"end":414},"obj":"Body_part"},{"id":"T104","span":{"begin":553,"end":558},"obj":"Body_part"},{"id":"T105","span":{"begin":590,"end":594},"obj":"Body_part"}],"attributes":[{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A102","pred":"fma_id","subj":"T102","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A103","pred":"fma_id","subj":"T103","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A104","pred":"fma_id","subj":"T104","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A105","pred":"fma_id","subj":"T105","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T9","span":{"begin":51,"end":55},"obj":"Body_part"}],"attributes":[{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T57","span":{"begin":148,"end":156},"obj":"Disease"},{"id":"T58","span":{"begin":434,"end":442},"obj":"Disease"},{"id":"T59","span":{"begin":631,"end":639},"obj":"Disease"}],"attributes":[{"id":"A57","pred":"mondo_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A58","pred":"mondo_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A59","pred":"mondo_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T81","span":{"begin":17,"end":24},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T82","span":{"begin":51,"end":55},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T83","span":{"begin":51,"end":55},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T84","span":{"begin":85,"end":94},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T85","span":{"begin":130,"end":137},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T86","span":{"begin":249,"end":258},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T87","span":{"begin":262,"end":269},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T88","span":{"begin":330,"end":332},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T89","span":{"begin":407,"end":414},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T90","span":{"begin":551,"end":558},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T91","span":{"begin":588,"end":594},"obj":"http://purl.obolibrary.org/obo/CL_0000084"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T71","span":{"begin":158,"end":160},"obj":"Chemical"},{"id":"T73","span":{"begin":240,"end":242},"obj":"Chemical"},{"id":"T75","span":{"begin":346,"end":348},"obj":"Chemical"},{"id":"T77","span":{"begin":473,"end":481},"obj":"Chemical"}],"attributes":[{"id":"A71","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A72","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A73","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A74","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A75","pred":"chebi_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A76","pred":"chebi_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A77","pred":"chebi_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T15","span":{"begin":482,"end":488},"obj":"http://purl.obolibrary.org/obo/GO_0007613"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}

{"project":"LitCovid-sentences","denotations":[{"id":"T22","span":{"begin":0,"end":640},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}

{"project":"LitCovid-PubTator","denotations":[{"id":"360","span":{"begin":158,"end":162},"obj":"Gene"},{"id":"361","span":{"begin":240,"end":244},"obj":"Gene"},{"id":"362","span":{"begin":337,"end":341},"obj":"Gene"},{"id":"363","span":{"begin":346,"end":351},"obj":"Gene"},{"id":"368","span":{"begin":420,"end":428},"obj":"Species"},{"id":"370","span":{"begin":51,"end":68},"obj":"Disease"},{"id":"371","span":{"begin":148,"end":156},"obj":"Disease"},{"id":"372","span":{"begin":434,"end":442},"obj":"Disease"},{"id":"373","span":{"begin":548,"end":552},"obj":"Disease"},{"id":"374","span":{"begin":631,"end":639},"obj":"Disease"}],"attributes":[{"id":"A360","pred":"tao:has_database_id","subj":"360","obj":"Gene:3565"},{"id":"A361","pred":"tao:has_database_id","subj":"361","obj":"Gene:3578"},{"id":"A362","pred":"tao:has_database_id","subj":"362","obj":"Gene:3458"},{"id":"A363","pred":"tao:has_database_id","subj":"363","obj":"Gene:3605"},{"id":"A368","pred":"tao:has_database_id","subj":"368","obj":"Tax:9606"},{"id":"A370","pred":"tao:has_database_id","subj":"370","obj":"MESH:D008171"},{"id":"A371","pred":"tao:has_database_id","subj":"371","obj":"MESH:C000657245"},{"id":"A372","pred":"tao:has_database_id","subj":"372","obj":"MESH:C000657245"},{"id":"A373","pred":"tao:has_database_id","subj":"373","obj":"MESH:D001260"},{"id":"A374","pred":"tao:has_database_id","subj":"374","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}

{"project":"2_test","denotations":[{"id":"33073244-27543964-66244526","span":{"begin":138,"end":140},"obj":"27543964"},{"id":"33073244-28555812-66244527","span":{"begin":142,"end":144},"obj":"28555812"},{"id":"33073244-32460357-66244528","span":{"begin":229,"end":231},"obj":"32460357"},{"id":"33073244-31986264-66244529","span":{"begin":327,"end":328},"obj":"31986264"},{"id":"33073244-32467616-66244530","span":{"begin":559,"end":561},"obj":"32467616"}],"text":"Both ILC2 and γδ T cells are centrally involved in lung homoeostasis and are rapidly activated in response to pathogens including viruses;19, 21 in COVID-19, IL-4 is upregulated at early stages and in milder forms of the disease,10 whereas IL-9 and activated γδ T cells are observed more frequently in mild-to-moderate disease,9, 22 and IFNγ and IL-17 progressively increase with disease severity.6 Vγ9Vδ2+ T cells from patients with COVID-19 have been found to express an effector memory phenotype three times more frequently than do conventional αβ T cells,23 thus suggesting that this T cell subset is selectively stimulated in COVID-19."}