PMC:7546716 / 43891-44068 JSONTXT

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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T895","span":{"begin":61,"end":65},"obj":"Body_part"},{"id":"T896","span":{"begin":61,"end":63},"obj":"Body_part"},{"id":"T897","span":{"begin":71,"end":73},"obj":"Body_part"},{"id":"T898","span":{"begin":164,"end":169},"obj":"Body_part"}],"attributes":[{"id":"A895","pred":"fma_id","subj":"T895","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A896","pred":"fma_id","subj":"T896","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A897","pred":"fma_id","subj":"T897","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A898","pred":"fma_id","subj":"T898","obj":"http://purl.org/sig/ont/fma/fma7088"}],"text":"Shown to inhibit caspase-1, thereby preventing activation of IL-1β and IL-18; effective in murine models of pulmonary inflammation; and have a potential benefit in heart failure"}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T52","span":{"begin":164,"end":169},"obj":"Body_part"}],"attributes":[{"id":"A52","pred":"uberon_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"}],"text":"Shown to inhibit caspase-1, thereby preventing activation of IL-1β and IL-18; effective in murine models of pulmonary inflammation; and have a potential benefit in heart failure"}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T254","span":{"begin":118,"end":130},"obj":"Disease"},{"id":"T255","span":{"begin":164,"end":177},"obj":"Disease"}],"attributes":[{"id":"A254","pred":"mondo_id","subj":"T254","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A255","pred":"mondo_id","subj":"T255","obj":"http://purl.obolibrary.org/obo/MONDO_0005252"}],"text":"Shown to inhibit caspase-1, thereby preventing activation of IL-1β and IL-18; effective in murine models of pulmonary inflammation; and have a potential benefit in heart failure"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T604","span":{"begin":47,"end":57},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T605","span":{"begin":74,"end":76},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T606","span":{"begin":141,"end":142},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T607","span":{"begin":164,"end":169},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T608","span":{"begin":164,"end":169},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T609","span":{"begin":164,"end":169},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T610","span":{"begin":164,"end":169},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"}],"text":"Shown to inhibit caspase-1, thereby preventing activation of IL-1β and IL-18; effective in murine models of pulmonary inflammation; and have a potential benefit in heart failure"}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T685","span":{"begin":61,"end":63},"obj":"Chemical"},{"id":"T687","span":{"begin":71,"end":73},"obj":"Chemical"}],"attributes":[{"id":"A685","pred":"chebi_id","subj":"T685","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A686","pred":"chebi_id","subj":"T685","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A687","pred":"chebi_id","subj":"T687","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A688","pred":"chebi_id","subj":"T687","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"}],"text":"Shown to inhibit caspase-1, thereby preventing activation of IL-1β and IL-18; effective in murine models of pulmonary inflammation; and have a potential benefit in heart failure"}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T82","span":{"begin":164,"end":177},"obj":"Phenotype"}],"attributes":[{"id":"A82","pred":"hp_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/HP_0001635"}],"text":"Shown to inhibit caspase-1, thereby preventing activation of IL-1β and IL-18; effective in murine models of pulmonary inflammation; and have a potential benefit in heart failure"}

    LitCovid-PD-GO-BP

    {"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T119","span":{"begin":118,"end":130},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Shown to inhibit caspase-1, thereby preventing activation of IL-1β and IL-18; effective in murine models of pulmonary inflammation; and have a potential benefit in heart failure"}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"1725","span":{"begin":17,"end":26},"obj":"Gene"},{"id":"1726","span":{"begin":61,"end":66},"obj":"Gene"},{"id":"1751","span":{"begin":91,"end":97},"obj":"Species"},{"id":"1801","span":{"begin":108,"end":130},"obj":"Disease"},{"id":"1802","span":{"begin":164,"end":177},"obj":"Disease"}],"attributes":[{"id":"A1725","pred":"tao:has_database_id","subj":"1725","obj":"Gene:834"},{"id":"A1726","pred":"tao:has_database_id","subj":"1726","obj":"Gene:3552"},{"id":"A1751","pred":"tao:has_database_id","subj":"1751","obj":"Tax:10090"},{"id":"A1801","pred":"tao:has_database_id","subj":"1801","obj":"MESH:D011014"},{"id":"A1802","pred":"tao:has_database_id","subj":"1802","obj":"MESH:D006333"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Shown to inhibit caspase-1, thereby preventing activation of IL-1β and IL-18; effective in murine models of pulmonary inflammation; and have a potential benefit in heart failure"}