PMC:7546716 / 40604-40981 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T800","span":{"begin":0,"end":8},"obj":"Body_part"},{"id":"T801","span":{"begin":85,"end":92},"obj":"Body_part"},{"id":"T802","span":{"begin":105,"end":119},"obj":"Body_part"},{"id":"T803","span":{"begin":105,"end":109},"obj":"Body_part"},{"id":"T804","span":{"begin":143,"end":148},"obj":"Body_part"},{"id":"T805","span":{"begin":224,"end":226},"obj":"Body_part"}],"attributes":[{"id":"A800","pred":"fma_id","subj":"T800","obj":"http://purl.org/sig/ont/fma/fma82839"},{"id":"A801","pred":"fma_id","subj":"T801","obj":"http://purl.org/sig/ont/fma/fma67110"},{"id":"A802","pred":"fma_id","subj":"T802","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A803","pred":"fma_id","subj":"T803","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A804","pred":"fma_id","subj":"T804","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A805","pred":"fma_id","subj":"T805","obj":"http://purl.org/sig/ont/fma/fma86578"}],"text":"Heparins (and small molecule toll-like receptor 2 inhibitors) Virus interaction with heparan sulphate on cell membranes Virus-susceptible host cells Possibly block coronavirus-induced, toll-like receptor 2-mediated, TNF and IL-6 production; might inhibit virus entry; and have antithrombotic effects Effective dose and best route of administration are unclear; risk of bleeding"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T555","span":{"begin":62,"end":67},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T556","span":{"begin":105,"end":109},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T557","span":{"begin":110,"end":119},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T558","span":{"begin":120,"end":125},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T559","span":{"begin":143,"end":148},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T560","span":{"begin":255,"end":260},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Heparins (and small molecule toll-like receptor 2 inhibitors) Virus interaction with heparan sulphate on cell membranes Virus-susceptible host cells Possibly block coronavirus-induced, toll-like receptor 2-mediated, TNF and IL-6 production; might inhibit virus entry; and have antithrombotic effects Effective dose and best route of administration are unclear; risk of bleeding"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T620","span":{"begin":20,"end":28},"obj":"Chemical"},{"id":"T621","span":{"begin":50,"end":60},"obj":"Chemical"},{"id":"T622","span":{"begin":85,"end":92},"obj":"Chemical"},{"id":"T623","span":{"begin":93,"end":101},"obj":"Chemical"},{"id":"T624","span":{"begin":224,"end":226},"obj":"Chemical"}],"attributes":[{"id":"A620","pred":"chebi_id","subj":"T620","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A621","pred":"chebi_id","subj":"T621","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A622","pred":"chebi_id","subj":"T622","obj":"http://purl.obolibrary.org/obo/CHEBI_24500"},{"id":"A623","pred":"chebi_id","subj":"T623","obj":"http://purl.obolibrary.org/obo/CHEBI_16189"},{"id":"A624","pred":"chebi_id","subj":"T624","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A625","pred":"chebi_id","subj":"T624","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"}],"text":"Heparins (and small molecule toll-like receptor 2 inhibitors) Virus interaction with heparan sulphate on cell membranes Virus-susceptible host cells Possibly block coronavirus-induced, toll-like receptor 2-mediated, TNF and IL-6 production; might inhibit virus entry; and have antithrombotic effects Effective dose and best route of administration are unclear; risk of bleeding"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T110","span":{"begin":224,"end":239},"obj":"http://purl.obolibrary.org/obo/GO_0032635"}],"text":"Heparins (and small molecule toll-like receptor 2 inhibitors) Virus interaction with heparan sulphate on cell membranes Virus-susceptible host cells Possibly block coronavirus-induced, toll-like receptor 2-mediated, TNF and IL-6 production; might inhibit virus entry; and have antithrombotic effects Effective dose and best route of administration are unclear; risk of bleeding"}

{"project":"LitCovid-sentences","denotations":[{"id":"T178","span":{"begin":0,"end":377},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Heparins (and small molecule toll-like receptor 2 inhibitors) Virus interaction with heparan sulphate on cell membranes Virus-susceptible host cells Possibly block coronavirus-induced, toll-like receptor 2-mediated, TNF and IL-6 production; might inhibit virus entry; and have antithrombotic effects Effective dose and best route of administration are unclear; risk of bleeding"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1683","span":{"begin":29,"end":49},"obj":"Gene"},{"id":"1684","span":{"begin":185,"end":205},"obj":"Gene"},{"id":"1685","span":{"begin":216,"end":219},"obj":"Gene"},{"id":"1686","span":{"begin":224,"end":228},"obj":"Gene"},{"id":"1750","span":{"begin":164,"end":175},"obj":"Species"},{"id":"1780","span":{"begin":369,"end":377},"obj":"Disease"}],"attributes":[{"id":"A1683","pred":"tao:has_database_id","subj":"1683","obj":"Gene:7097"},{"id":"A1684","pred":"tao:has_database_id","subj":"1684","obj":"Gene:7097"},{"id":"A1685","pred":"tao:has_database_id","subj":"1685","obj":"Gene:7124"},{"id":"A1686","pred":"tao:has_database_id","subj":"1686","obj":"Gene:3569"},{"id":"A1750","pred":"tao:has_database_id","subj":"1750","obj":"Tax:11118"},{"id":"A1780","pred":"tao:has_database_id","subj":"1780","obj":"MESH:D006470"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Heparins (and small molecule toll-like receptor 2 inhibitors) Virus interaction with heparan sulphate on cell membranes Virus-susceptible host cells Possibly block coronavirus-induced, toll-like receptor 2-mediated, TNF and IL-6 production; might inhibit virus entry; and have antithrombotic effects Effective dose and best route of administration are unclear; risk of bleeding"}