PMC:7546716 / 35277-36299 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T642","span":{"begin":0,"end":8},"obj":"Body_part"},{"id":"T643","span":{"begin":27,"end":29},"obj":"Body_part"},{"id":"T644","span":{"begin":37,"end":40},"obj":"Body_part"},{"id":"T645","span":{"begin":42,"end":46},"obj":"Body_part"},{"id":"T646","span":{"begin":42,"end":44},"obj":"Body_part"},{"id":"T647","span":{"begin":53,"end":57},"obj":"Body_part"},{"id":"T648","span":{"begin":53,"end":55},"obj":"Body_part"},{"id":"T649","span":{"begin":68,"end":77},"obj":"Body_part"},{"id":"T650","span":{"begin":79,"end":89},"obj":"Body_part"},{"id":"T651","span":{"begin":125,"end":129},"obj":"Body_part"},{"id":"T652","span":{"begin":156,"end":160},"obj":"Body_part"},{"id":"T653","span":{"begin":271,"end":280},"obj":"Body_part"},{"id":"T654","span":{"begin":305,"end":314},"obj":"Body_part"},{"id":"T655","span":{"begin":340,"end":349},"obj":"Body_part"},{"id":"T656","span":{"begin":368,"end":377},"obj":"Body_part"},{"id":"T657","span":{"begin":393,"end":403},"obj":"Body_part"},{"id":"T658","span":{"begin":412,"end":419},"obj":"Body_part"},{"id":"T659","span":{"begin":438,"end":448},"obj":"Body_part"},{"id":"T660","span":{"begin":494,"end":497},"obj":"Body_part"},{"id":"T661","span":{"begin":498,"end":509},"obj":"Body_part"},{"id":"T662","span":{"begin":510,"end":520},"obj":"Body_part"},{"id":"T663","span":{"begin":577,"end":579},"obj":"Body_part"},{"id":"T664","span":{"begin":580,"end":591},"obj":"Body_part"},{"id":"T665","span":{"begin":621,"end":625},"obj":"Body_part"},{"id":"T666","span":{"begin":689,"end":696},"obj":"Body_part"},{"id":"T667","span":{"begin":703,"end":711},"obj":"Body_part"},{"id":"T668","span":{"begin":743,"end":751},"obj":"Body_part"},{"id":"T669","span":{"begin":810,"end":821},"obj":"Body_part"},{"id":"T670","span":{"begin":963,"end":980},"obj":"Body_part"},{"id":"T671","span":{"begin":976,"end":980},"obj":"Body_part"}],"attributes":[{"id":"A642","pred":"fma_id","subj":"T642","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A643","pred":"fma_id","subj":"T643","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A644","pred":"fma_id","subj":"T644","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A645","pred":"fma_id","subj":"T645","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A646","pred":"fma_id","subj":"T646","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A647","pred":"fma_id","subj":"T647","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A648","pred":"fma_id","subj":"T648","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A649","pred":"fma_id","subj":"T649","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A650","pred":"fma_id","subj":"T650","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A651","pred":"fma_id","subj":"T651","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A652","pred":"fma_id","subj":"T652","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A653","pred":"fma_id","subj":"T653","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A654","pred":"fma_id","subj":"T654","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A655","pred":"fma_id","subj":"T655","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A656","pred":"fma_id","subj":"T656","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A657","pred":"fma_id","subj":"T657","obj":"http://purl.org/sig/ont/fma/fma82738"},{"id":"A658","pred":"fma_id","subj":"T658","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A659","pred":"fma_id","subj":"T659","obj":"http://purl.org/sig/ont/fma/fma63877"},{"id":"A660","pred":"fma_id","subj":"T660","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A661","pred":"fma_id","subj":"T661","obj":"http://purl.org/sig/ont/fma/fma62854"},{"id":"A662","pred":"fma_id","subj":"T662","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A663","pred":"fma_id","subj":"T663","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A664","pred":"fma_id","subj":"T664","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A665","pred":"fma_id","subj":"T665","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A666","pred":"fma_id","subj":"T666","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A667","pred":"fma_id","subj":"T667","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A668","pred":"fma_id","subj":"T668","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A669","pred":"fma_id","subj":"T669","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A670","pred":"fma_id","subj":"T670","obj":"http://purl.org/sig/ont/fma/fma84070"},{"id":"A671","pred":"fma_id","subj":"T671","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Cytokine interplay between IL-33, GM-CSF, IL-1α, and IL-1β, and key cytokines, chemokines, and receptors, the composition of lung inflammatory infiltrates, cell phenotypes involved, and possible therapeutic options according to different stages of disease. 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{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T48","span":{"begin":125,"end":129},"obj":"Body_part"}],"attributes":[{"id":"A48","pred":"uberon_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Cytokine interplay between IL-33, GM-CSF, IL-1α, and IL-1β, and key cytokines, chemokines, and receptors, the composition of lung inflammatory infiltrates, cell phenotypes involved, and possible therapeutic options according to different stages of disease. CCR=C-C motif chemokine receptor. CCL=C-C motif chemokine ligand. CXCL=C-X-C motif chemokine. CXCR=C-X-C motif chemokine receptor. FABP=fatty acid-binding protein. FCN=ficolin. FGF=fibroblast growth factors. GATA=GATA-binding factor. GM-CSF=granulocyte-macrophage colony-stimulating factor. i=inhibitor. IFN=interferon. IL=interleukin. ILC2=type 2 innate lymphoid cell. JAK=Janus kinase. NLRP=NACHT, LRR, and PYD domains-containing protein. PDGF=platelet-derived growth factor. PDGF-Ri=platelet-derived growth factor receptor inhibitor. rIL=recombinant interleukin. SPP=secreted phosphoprotein. sST2= soluble ST2. ST2=ST2 receptor. TGF=transforming growth factor. Th=T-helper. TLR=toll-like receptor. Treg=regulatory T cell. VEGF=vascular endothelial growth factor."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T207","span":{"begin":257,"end":264},"obj":"Disease"}],"attributes":[{"id":"A207","pred":"mondo_id","subj":"T207","obj":"http://purl.obolibrary.org/obo/MONDO_0007763"}],"text":"Cytokine interplay between IL-33, GM-CSF, IL-1α, and IL-1β, and key cytokines, chemokines, and receptors, the composition of lung inflammatory infiltrates, cell phenotypes involved, and possible therapeutic options according to different stages of disease. CCR=C-C motif chemokine receptor. CCL=C-C motif chemokine ligand. CXCL=C-X-C motif chemokine. CXCR=C-X-C motif chemokine receptor. FABP=fatty acid-binding protein. FCN=ficolin. FGF=fibroblast growth factors. GATA=GATA-binding factor. GM-CSF=granulocyte-macrophage colony-stimulating factor. i=inhibitor. IFN=interferon. IL=interleukin. ILC2=type 2 innate lymphoid cell. JAK=Janus kinase. NLRP=NACHT, LRR, and PYD domains-containing protein. PDGF=platelet-derived growth factor. PDGF-Ri=platelet-derived growth factor receptor inhibitor. rIL=recombinant interleukin. SPP=secreted phosphoprotein. sST2= soluble ST2. ST2=ST2 receptor. TGF=transforming growth factor. Th=T-helper. TLR=toll-like receptor. Treg=regulatory T cell. VEGF=vascular endothelial growth factor."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T478","span":{"begin":125,"end":129},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T479","span":{"begin":125,"end":129},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T480","span":{"begin":156,"end":160},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T481","span":{"begin":330,"end":333},"obj":"http://purl.obolibrary.org/obo/CLO_0009645"},{"id":"T482","span":{"begin":330,"end":333},"obj":"http://purl.obolibrary.org/obo/CLO_0050824"},{"id":"T483","span":{"begin":358,"end":361},"obj":"http://purl.obolibrary.org/obo/CLO_0009645"},{"id":"T484","span":{"begin":358,"end":361},"obj":"http://purl.obolibrary.org/obo/CLO_0050824"},{"id":"T485","span":{"begin":438,"end":448},"obj":"http://purl.obolibrary.org/obo/CL_0000057"},{"id":"T486","span":{"begin":605,"end":625},"obj":"http://purl.obolibrary.org/obo/CL_0001065"},{"id":"T487","span":{"begin":866,"end":869},"obj":"http://purl.obolibrary.org/obo/CLO_0051025"},{"id":"T488","span":{"begin":871,"end":874},"obj":"http://purl.obolibrary.org/obo/CLO_0051025"},{"id":"T489","span":{"begin":875,"end":878},"obj":"http://purl.obolibrary.org/obo/CLO_0051025"},{"id":"T490","span":{"begin":958,"end":962},"obj":"http://purl.obolibrary.org/obo/CL_0000792"},{"id":"T491","span":{"begin":963,"end":980},"obj":"http://purl.obolibrary.org/obo/CL_0000815"}],"text":"Cytokine interplay between IL-33, GM-CSF, IL-1α, and IL-1β, and key cytokines, chemokines, and receptors, the composition of lung inflammatory infiltrates, cell phenotypes involved, and possible therapeutic options according to different stages of disease. CCR=C-C motif chemokine receptor. CCL=C-C motif chemokine ligand. CXCL=C-X-C motif chemokine. CXCR=C-X-C motif chemokine receptor. FABP=fatty acid-binding protein. FCN=ficolin. FGF=fibroblast growth factors. GATA=GATA-binding factor. GM-CSF=granulocyte-macrophage colony-stimulating factor. i=inhibitor. IFN=interferon. IL=interleukin. ILC2=type 2 innate lymphoid cell. JAK=Janus kinase. NLRP=NACHT, LRR, and PYD domains-containing protein. PDGF=platelet-derived growth factor. PDGF-Ri=platelet-derived growth factor receptor inhibitor. rIL=recombinant interleukin. SPP=secreted phosphoprotein. sST2= soluble ST2. ST2=ST2 receptor. TGF=transforming growth factor. Th=T-helper. TLR=toll-like receptor. Treg=regulatory T cell. VEGF=vascular endothelial growth factor."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T513","span":{"begin":27,"end":29},"obj":"Chemical"},{"id":"T515","span":{"begin":34,"end":36},"obj":"Chemical"},{"id":"T516","span":{"begin":42,"end":44},"obj":"Chemical"},{"id":"T518","span":{"begin":53,"end":55},"obj":"Chemical"},{"id":"T520","span":{"begin":291,"end":294},"obj":"Chemical"},{"id":"T521","span":{"begin":315,"end":321},"obj":"Chemical"},{"id":"T522","span":{"begin":393,"end":403},"obj":"Chemical"},{"id":"T523","span":{"begin":399,"end":403},"obj":"Chemical"},{"id":"T524","span":{"begin":412,"end":419},"obj":"Chemical"},{"id":"T525","span":{"begin":491,"end":493},"obj":"Chemical"},{"id":"T526","span":{"begin":550,"end":559},"obj":"Chemical"},{"id":"T527","span":{"begin":565,"end":575},"obj":"Chemical"},{"id":"T528","span":{"begin":577,"end":579},"obj":"Chemical"},{"id":"T530","span":{"begin":689,"end":696},"obj":"Chemical"},{"id":"T531","span":{"begin":783,"end":792},"obj":"Chemical"},{"id":"T532","span":{"begin":921,"end":923},"obj":"Chemical"}],"attributes":[{"id":"A513","pred":"chebi_id","subj":"T513","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A514","pred":"chebi_id","subj":"T513","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A515","pred":"chebi_id","subj":"T515","obj":"http://purl.obolibrary.org/obo/CHEBI_74120"},{"id":"A516","pred":"chebi_id","subj":"T516","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A517","pred":"chebi_id","subj":"T516","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A518","pred":"chebi_id","subj":"T518","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A519","pred":"chebi_id","subj":"T518","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A520","pred":"chebi_id","subj":"T520","obj":"http://purl.obolibrary.org/obo/CHEBI_3478"},{"id":"A521","pred":"chebi_id","subj":"T521","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A522","pred":"chebi_id","subj":"T522","obj":"http://purl.obolibrary.org/obo/CHEBI_35366"},{"id":"A523","pred":"chebi_id","subj":"T523","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A524","pred":"chebi_id","subj":"T524","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A525","pred":"chebi_id","subj":"T525","obj":"http://purl.obolibrary.org/obo/CHEBI_74120"},{"id":"A526","pred":"chebi_id","subj":"T526","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A527","pred":"chebi_id","subj":"T527","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A528","pred":"chebi_id","subj":"T528","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A529","pred":"chebi_id","subj":"T528","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A530","pred":"chebi_id","subj":"T530","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A531","pred":"chebi_id","subj":"T531","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A532","pred":"chebi_id","subj":"T532","obj":"http://purl.obolibrary.org/obo/CHEBI_33385"}],"text":"Cytokine interplay between IL-33, GM-CSF, IL-1α, and IL-1β, and key cytokines, chemokines, and receptors, the composition of lung inflammatory infiltrates, cell phenotypes involved, and possible therapeutic options according to different stages of disease. CCR=C-C motif chemokine receptor. CCL=C-C motif chemokine ligand. CXCL=C-X-C motif chemokine. CXCR=C-X-C motif chemokine receptor. FABP=fatty acid-binding protein. FCN=ficolin. FGF=fibroblast growth factors. GATA=GATA-binding factor. GM-CSF=granulocyte-macrophage colony-stimulating factor. i=inhibitor. IFN=interferon. IL=interleukin. ILC2=type 2 innate lymphoid cell. JAK=Janus kinase. NLRP=NACHT, LRR, and PYD domains-containing protein. PDGF=platelet-derived growth factor. PDGF-Ri=platelet-derived growth factor receptor inhibitor. rIL=recombinant interleukin. SPP=secreted phosphoprotein. sST2= soluble ST2. ST2=ST2 receptor. TGF=transforming growth factor. Th=T-helper. TLR=toll-like receptor. Treg=regulatory T cell. VEGF=vascular endothelial growth factor."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T98","span":{"begin":449,"end":455},"obj":"http://purl.obolibrary.org/obo/GO_0040007"},{"id":"T99","span":{"begin":720,"end":726},"obj":"http://purl.obolibrary.org/obo/GO_0040007"},{"id":"T100","span":{"begin":760,"end":766},"obj":"http://purl.obolibrary.org/obo/GO_0040007"},{"id":"T101","span":{"begin":906,"end":912},"obj":"http://purl.obolibrary.org/obo/GO_0040007"},{"id":"T102","span":{"begin":1008,"end":1014},"obj":"http://purl.obolibrary.org/obo/GO_0040007"}],"text":"Cytokine interplay between IL-33, GM-CSF, IL-1α, and IL-1β, and key cytokines, chemokines, and receptors, the composition of lung inflammatory infiltrates, cell phenotypes involved, and possible therapeutic options according to different stages of disease. CCR=C-C motif chemokine receptor. CCL=C-C motif chemokine ligand. CXCL=C-X-C motif chemokine. CXCR=C-X-C motif chemokine receptor. FABP=fatty acid-binding protein. FCN=ficolin. FGF=fibroblast growth factors. GATA=GATA-binding factor. GM-CSF=granulocyte-macrophage colony-stimulating factor. i=inhibitor. IFN=interferon. IL=interleukin. ILC2=type 2 innate lymphoid cell. JAK=Janus kinase. NLRP=NACHT, LRR, and PYD domains-containing protein. PDGF=platelet-derived growth factor. PDGF-Ri=platelet-derived growth factor receptor inhibitor. rIL=recombinant interleukin. SPP=secreted phosphoprotein. sST2= soluble ST2. ST2=ST2 receptor. TGF=transforming growth factor. Th=T-helper. TLR=toll-like receptor. Treg=regulatory T cell. VEGF=vascular endothelial growth factor."}

{"project":"LitCovid-sentences","denotations":[{"id":"T144","span":{"begin":0,"end":256},"obj":"Sentence"},{"id":"T145","span":{"begin":257,"end":290},"obj":"Sentence"},{"id":"T146","span":{"begin":291,"end":322},"obj":"Sentence"},{"id":"T147","span":{"begin":323,"end":350},"obj":"Sentence"},{"id":"T148","span":{"begin":351,"end":387},"obj":"Sentence"},{"id":"T149","span":{"begin":388,"end":420},"obj":"Sentence"},{"id":"T150","span":{"begin":421,"end":433},"obj":"Sentence"},{"id":"T151","span":{"begin":434,"end":464},"obj":"Sentence"},{"id":"T152","span":{"begin":465,"end":490},"obj":"Sentence"},{"id":"T153","span":{"begin":491,"end":560},"obj":"Sentence"},{"id":"T154","span":{"begin":561,"end":576},"obj":"Sentence"},{"id":"T155","span":{"begin":577,"end":592},"obj":"Sentence"},{"id":"T156","span":{"begin":593,"end":626},"obj":"Sentence"},{"id":"T157","span":{"begin":627,"end":644},"obj":"Sentence"},{"id":"T158","span":{"begin":645,"end":697},"obj":"Sentence"},{"id":"T159","span":{"begin":698,"end":734},"obj":"Sentence"},{"id":"T160","span":{"begin":735,"end":822},"obj":"Sentence"},{"id":"T161","span":{"begin":823,"end":870},"obj":"Sentence"},{"id":"T162","span":{"begin":871,"end":888},"obj":"Sentence"},{"id":"T163","span":{"begin":889,"end":920},"obj":"Sentence"},{"id":"T164","span":{"begin":921,"end":933},"obj":"Sentence"},{"id":"T165","span":{"begin":934,"end":957},"obj":"Sentence"},{"id":"T166","span":{"begin":958,"end":981},"obj":"Sentence"},{"id":"T167","span":{"begin":982,"end":1022},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Cytokine interplay between IL-33, GM-CSF, IL-1α, and IL-1β, and key cytokines, chemokines, and receptors, the composition of lung inflammatory infiltrates, cell phenotypes involved, and possible therapeutic options according to different stages of disease. CCR=C-C motif chemokine receptor. CCL=C-C motif chemokine ligand. CXCL=C-X-C motif chemokine. CXCR=C-X-C motif chemokine receptor. FABP=fatty acid-binding protein. FCN=ficolin. FGF=fibroblast growth factors. GATA=GATA-binding factor. GM-CSF=granulocyte-macrophage colony-stimulating factor. i=inhibitor. IFN=interferon. IL=interleukin. ILC2=type 2 innate lymphoid cell. JAK=Janus kinase. NLRP=NACHT, LRR, and PYD domains-containing protein. PDGF=platelet-derived growth factor. PDGF-Ri=platelet-derived growth factor receptor inhibitor. rIL=recombinant interleukin. SPP=secreted phosphoprotein. sST2= soluble ST2. ST2=ST2 receptor. TGF=transforming growth factor. Th=T-helper. TLR=toll-like receptor. Treg=regulatory T cell. VEGF=vascular endothelial growth factor."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1461","span":{"begin":27,"end":32},"obj":"Gene"},{"id":"1462","span":{"begin":34,"end":40},"obj":"Gene"},{"id":"1463","span":{"begin":42,"end":47},"obj":"Gene"},{"id":"1464","span":{"begin":53,"end":58},"obj":"Gene"},{"id":"1465","span":{"begin":465,"end":489},"obj":"Gene"},{"id":"1466","span":{"begin":627,"end":630},"obj":"Gene"},{"id":"1467","span":{"begin":866,"end":869},"obj":"Gene"},{"id":"1468","span":{"begin":982,"end":986},"obj":"Gene"},{"id":"1469","span":{"begin":987,"end":1021},"obj":"Gene"},{"id":"1470","span":{"begin":650,"end":655},"obj":"Gene"},{"id":"1471","span":{"begin":657,"end":660},"obj":"Gene"},{"id":"1472","span":{"begin":328,"end":333},"obj":"Chemical"},{"id":"1473","span":{"begin":393,"end":403},"obj":"Chemical"}],"attributes":[{"id":"A1461","pred":"tao:has_database_id","subj":"1461","obj":"Gene:90865"},{"id":"A1462","pred":"tao:has_database_id","subj":"1462","obj":"Gene:1437"},{"id":"A1463","pred":"tao:has_database_id","subj":"1463","obj":"Gene:3552"},{"id":"A1464","pred":"tao:has_database_id","subj":"1464","obj":"Gene:3552"},{"id":"A1465","pred":"tao:has_database_id","subj":"1465","obj":"Gene:55278"},{"id":"A1466","pred":"tao:has_database_id","subj":"1466","obj":"Gene:3717"},{"id":"A1467","pred":"tao:has_database_id","subj":"1467","obj":"Gene:6761"},{"id":"A1468","pred":"tao:has_database_id","subj":"1468","obj":"Gene:7422"},{"id":"A1469","pred":"tao:has_database_id","subj":"1469","obj":"Gene:7422"},{"id":"A1470","pred":"tao:has_database_id","subj":"1470","obj":"Gene:114548"},{"id":"A1471","pred":"tao:has_database_id","subj":"1471","obj":"Gene:114548"},{"id":"A1473","pred":"tao:has_database_id","subj":"1473","obj":"MESH:D005227"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Cytokine interplay between IL-33, GM-CSF, IL-1α, and IL-1β, and key cytokines, chemokines, and receptors, the composition of lung inflammatory infiltrates, cell phenotypes involved, and possible therapeutic options according to different stages of disease. CCR=C-C motif chemokine receptor. CCL=C-C motif chemokine ligand. CXCL=C-X-C motif chemokine. CXCR=C-X-C motif chemokine receptor. FABP=fatty acid-binding protein. FCN=ficolin. FGF=fibroblast growth factors. GATA=GATA-binding factor. GM-CSF=granulocyte-macrophage colony-stimulating factor. i=inhibitor. IFN=interferon. IL=interleukin. ILC2=type 2 innate lymphoid cell. JAK=Janus kinase. NLRP=NACHT, LRR, and PYD domains-containing protein. PDGF=platelet-derived growth factor. PDGF-Ri=platelet-derived growth factor receptor inhibitor. rIL=recombinant interleukin. SPP=secreted phosphoprotein. sST2= soluble ST2. ST2=ST2 receptor. TGF=transforming growth factor. Th=T-helper. TLR=toll-like receptor. Treg=regulatory T cell. VEGF=vascular endothelial growth factor."}