PMC:7546716 / 31382-32090
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T587 | 222-226 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
| T588 | 222-224 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T589 | 232-236 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
| T590 | 232-234 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T591 | 255-257 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T592 | 298-301 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T593 | 402-404 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T594 | 542-544 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T595 | 551-553 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T596 | 620-622 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T187 | 184-192 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T188 | 435-443 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T429 | 591-593 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T456 | 222-224 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T458 | 232-234 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T460 | 255-257 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T462 | 295-297 | Chemical | denotes | GM | http://purl.obolibrary.org/obo/CHEBI_74120 |
| T463 | 402-404 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T465 | 542-544 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T467 | 551-553 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T469 | 620-622 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T471 | 650-661 | Chemical | denotes | tocilizumab | http://purl.obolibrary.org/obo/CHEBI_64360 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T88 | 255-261 | http://purl.obolibrary.org/obo/GO_0005152 | denotes | IL-1RA |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T134 | 0-708 | Sentence | denotes | Although more conclusive results are awaited from randomised controlled trials, encouraging preliminary results have been reported for the successful management of severe and critical COVID-19 by therapeutic modulation of IL-1α and IL-1β with recombinant IL-1RA (anakinra)84, 85 and by blocking GM-CSF using monoclonal antibodies (mavrilimumab, lenzilumab).86, 87 Although some studies have shown that IL-6 peaks at advanced stages of COVID-19 and is associated with disease severity,2, 10, 15 other studies have reported conflicting data on IL-6 and IL-6 receptor expression in patients,9, 11 and the results with anti-IL-6 receptor antibodies (eg, tocilizumab, sarilumab) have been controversial.88, 89, 90 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1335 | 222-227 | Gene | denotes | IL-1α | Gene:3552 |
| 1336 | 232-237 | Gene | denotes | IL-1β | Gene:3552 |
| 1337 | 255-261 | Gene | denotes | IL-1RA | Gene:3557 |
| 1338 | 295-301 | Gene | denotes | GM-CSF | Gene:1437 |
| 1339 | 402-406 | Gene | denotes | IL-6 | Gene:3569 |
| 1340 | 542-546 | Gene | denotes | IL-6 | Gene:3569 |
| 1341 | 579-587 | Species | denotes | patients | Tax:9606 |
| 1342 | 650-661 | Chemical | denotes | tocilizumab | MESH:C502936 |
| 1343 | 663-672 | Chemical | denotes | sarilumab | MESH:C000592401 |
| 1344 | 184-192 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1345 | 435-443 | Disease | denotes | COVID-19 | MESH:C000657245 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 33073244-32501454-66244638 | 272-274 | 32501454 | denotes | 84 |
| 33073244-32411313-66244639 | 276-278 | 32411313 | denotes | 85 |
| 33073244-32835256-66244640 | 357-359 | 32835256 | denotes | 86 |
| 33073244-32460357-66244641 | 487-489 | 32460357 | denotes | 10 |
| 33073244-32398875-66244642 | 491-493 | 32398875 | denotes | 15 |
| 33073244-31986264-66244643 | 588-589 | 31986264 | denotes | 9 |
| 33073244-32228226-66244644 | 591-593 | 32228226 | denotes | 11 |
| 33073244-32405160-66244645 | 698-700 | 32405160 | denotes | 88 |