PMC:7546716 / 14475-15346
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T247 | 11-22 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
| T248 | 101-116 | Body_part | denotes | dendritic cells | http://purl.org/sig/ont/fma/fma273565 |
| T249 | 111-116 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T250 | 149-159 | Body_part | denotes | lymphocyte | http://purl.org/sig/ont/fma/fma62863 |
| T251 | 175-177 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T252 | 184-188 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T253 | 184-186 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T254 | 212-216 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T255 | 264-268 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T256 | 264-266 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T257 | 273-275 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T258 | 281-286 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T259 | 345-349 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T260 | 345-347 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T261 | 354-356 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T262 | 418-420 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T263 | 439-444 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T264 | 460-462 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T265 | 550-552 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T266 | 590-595 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T267 | 610-613 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T268 | 711-716 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T269 | 738-742 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T270 | 738-740 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
| T271 | 793-798 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T272 | 864-866 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T16 | 281-286 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T92 | 316-324 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T93 | 658-666 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T198 | 80-87 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signals |
| T199 | 101-116 | http://purl.obolibrary.org/obo/CL_0000451 | denotes | dendritic cells |
| T200 | 184-188 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T201 | 210-216 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T-cell |
| T202 | 264-268 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T203 | 345-349 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T204 | 437-444 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T205 | 478-484 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
| T206 | 500-509 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activator |
| T207 | 588-595 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T208 | 632-634 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T209 | 701-704 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T210 | 709-716 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T211 | 738-742 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T212 | 752-756 | http://purl.obolibrary.org/obo/PR_000001380 | denotes | CD25 |
| T213 | 793-798 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T214 | 839-848 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T180 | 54-62 | Chemical | denotes | antigens | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T181 | 175-177 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T183 | 184-186 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T185 | 264-266 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T187 | 273-275 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T189 | 345-347 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T191 | 354-356 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T193 | 418-420 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T195 | 460-462 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T197 | 550-552 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T199 | 607-609 | Chemical | denotes | GM | http://purl.obolibrary.org/obo/CHEBI_74120 |
| T200 | 738-740 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T202 | 765-767 | Chemical | denotes | PD | http://purl.obolibrary.org/obo/CHEBI_74756 |
| T203 | 864-866 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T36 | 160-166 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
| T37 | 513-526 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T68 | 0-240 | Sentence | denotes | Failure of lymphocytes to adequately respond to viral antigens and proapoptotic signals might induce dendritic cells to produce large amounts of the lymphocyte growth factors IL-7 and IL-2, thereby stimulating T-cell survival and expansion. |
| T69 | 241-871 | Sentence | denotes | High concentrations of IL-2 and IL-7 in serum are characteristic of severe COVID-19 cases.6, 9 However, IL-2 and IL-7 might amplify ILC2 survival and differentiation induced by IL-33,33 expand γδ T cells, which produce IL-17 through the signal transducer and activator of transcription (STAT)3,34 and enhance IL-33-induced pathologic expansion of T cells expressing GM-CSF through STAT5.35, 36 Patients infected with SARS-CoV-2 show an increase in circulating CD4+ γδ T cells that overexpress the IL-2 receptor CD25 but not PD-1, suggesting that these cells are not exhausted, but are specifically activated in response to IL-2.22 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 601 | 175-179 | Gene | denotes | IL-7 | Gene:3574 |
| 602 | 184-188 | Gene | denotes | IL-2 | Gene:3558 |
| 603 | 264-268 | Gene | denotes | IL-2 | Gene:3558 |
| 604 | 273-277 | Gene | denotes | IL-7 | Gene:3574 |
| 605 | 345-349 | Gene | denotes | IL-2 | Gene:3558 |
| 606 | 354-358 | Gene | denotes | IL-7 | Gene:3574 |
| 607 | 418-423 | Gene | denotes | IL-33 | Gene:90865 |
| 608 | 460-465 | Gene | denotes | IL-17 | Gene:3605 |
| 609 | 478-534 | Gene | denotes | signal transducer and activator of transcription (STAT)3 | Gene:6774 |
| 610 | 550-555 | Gene | denotes | IL-33 | Gene:90865 |
| 611 | 607-613 | Gene | denotes | GM-CSF | Gene:1437 |
| 612 | 622-627 | Gene | denotes | STAT5 | Gene:6776 |
| 613 | 701-704 | Gene | denotes | CD4 | Gene:920 |
| 614 | 738-742 | Gene | denotes | IL-2 | Gene:3558 |
| 615 | 864-868 | Gene | denotes | IL-2 | Gene:101055066 |
| 616 | 635-643 | Species | denotes | Patients | Tax:9606 |
| 617 | 658-668 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 618 | 316-324 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 619 | 644-652 | Disease | denotes | infected | MESH:D007239 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 33073244-31986264-66244553 | 334-335 | 31986264 | denotes | 9 |
| 33073244-22425247-66244554 | 424-426 | 22425247 | denotes | 33 |
| 33073244-23047700-66244555 | 535-537 | 23047700 | denotes | 34 |
| 33073244-25412660-66244556 | 628-630 | 25412660 | denotes | 35 |
| 33073244-30949175-66244557 | 632-634 | 30949175 | denotes | 36 |