PMC:7546139 / 7211-8929 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T9","span":{"begin":149,"end":162},"obj":"Body_part"},{"id":"T10","span":{"begin":273,"end":279},"obj":"Body_part"},{"id":"T11","span":{"begin":343,"end":348},"obj":"Body_part"},{"id":"T12","span":{"begin":605,"end":612},"obj":"Body_part"},{"id":"T13","span":{"begin":663,"end":669},"obj":"Body_part"},{"id":"T14","span":{"begin":787,"end":793},"obj":"Body_part"},{"id":"T15","span":{"begin":888,"end":894},"obj":"Body_part"},{"id":"T16","span":{"begin":965,"end":971},"obj":"Body_part"},{"id":"T17","span":{"begin":1127,"end":1134},"obj":"Body_part"},{"id":"T18","span":{"begin":1223,"end":1228},"obj":"Body_part"},{"id":"T19","span":{"begin":1469,"end":1474},"obj":"Body_part"},{"id":"T20","span":{"begin":1488,"end":1501},"obj":"Body_part"},{"id":"T21","span":{"begin":1600,"end":1606},"obj":"Body_part"},{"id":"T22","span":{"begin":1644,"end":1650},"obj":"Body_part"}],"attributes":[{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma75151"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma55629"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma12516"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma55628"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma55629"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma55628"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma12516"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma314001"},{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma75151"},{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma55630"},{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma55630"}],"text":"Table 1 Direct restorative procedures (ie not involving a laboratory stage) for managing coronal and root surface carious lesions for permanent and primary teeth with high, low and non-AGP alternatives\nLesion location High AGP* Low AGP* Non-AGP\nCarious lesions limited to enamel\nSmooth surface N/A Resin infiltration Maximise fluoride during tooth brushing\nTopical fluoride therapy\n(Other remineralisation agents**)\nOcclusal surface N/A Resin fissure sealant ART/HVGIC sealant\nGIC sealant\nApproximal surface N/A Resin infiltration Fluoride\n(Other remineralisation agents**)\nCarious lesion extending into dentine or on root surface\nSmooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration\nNRCC\nSDF\nOcclusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration\nNRCC†\nSDF\nApproximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration\nStainless steel crown (conventional placement)\nZirconia crown Resin infiltration (outer 1/3 dentine) ART restoration†\nHall Technique\nNRCC†\nSDF†\nKey:\n* = use rubber dam with sealant around tooth/dam interface and high-volume aspiration\n** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth\n† = only for primary teeth\nART = atraumatic restorative treatment\nCMCR = chemo-mechanical caries removal\nGIC = glass-ionomer cement\nHVGIC = high-viscosity glass-ionomer cement\nNRCC = non-restorative cavity control\nSDF = silver diamine fluoride"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T5","span":{"begin":273,"end":279},"obj":"Body_part"},{"id":"T6","span":{"begin":605,"end":612},"obj":"Body_part"},{"id":"T7","span":{"begin":663,"end":669},"obj":"Body_part"},{"id":"T8","span":{"begin":787,"end":793},"obj":"Body_part"},{"id":"T9","span":{"begin":888,"end":894},"obj":"Body_part"},{"id":"T10","span":{"begin":965,"end":971},"obj":"Body_part"},{"id":"T11","span":{"begin":1127,"end":1134},"obj":"Body_part"}],"attributes":[{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/UBERON_0001752"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_0001751"},{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0001752"},{"id":"A10","pred":"uberon_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0001751"}],"text":"Table 1 Direct restorative procedures (ie not involving a laboratory stage) for managing coronal and root surface carious lesions for permanent and primary teeth with high, low and non-AGP alternatives\nLesion location High AGP* Low AGP* Non-AGP\nCarious lesions limited to enamel\nSmooth surface N/A Resin infiltration Maximise fluoride during tooth brushing\nTopical fluoride therapy\n(Other remineralisation agents**)\nOcclusal surface N/A Resin fissure sealant ART/HVGIC sealant\nGIC sealant\nApproximal surface N/A Resin infiltration Fluoride\n(Other remineralisation agents**)\nCarious lesion extending into dentine or on root surface\nSmooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration\nNRCC\nSDF\nOcclusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration\nNRCC†\nSDF\nApproximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration\nStainless steel crown (conventional placement)\nZirconia crown Resin infiltration (outer 1/3 dentine) ART restoration†\nHall Technique\nNRCC†\nSDF†\nKey:\n* = use rubber dam with sealant around tooth/dam interface and high-volume aspiration\n** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth\n† = only for primary teeth\nART = atraumatic restorative treatment\nCMCR = chemo-mechanical caries removal\nGIC = glass-ionomer cement\nHVGIC = high-viscosity glass-ionomer cement\nNRCC = non-restorative cavity control\nSDF = silver diamine fluoride"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T38","span":{"begin":57,"end":58},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T39","span":{"begin":297,"end":298},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T40","span":{"begin":436,"end":437},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T41","span":{"begin":511,"end":512},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T42","span":{"begin":735,"end":736},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T43","span":{"begin":1355,"end":1363},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T44","span":{"begin":1674,"end":1680},"obj":"http://purl.obolibrary.org/obo/UBERON_0002553"}],"text":"Table 1 Direct restorative procedures (ie not involving a laboratory stage) for managing coronal and root surface carious lesions for permanent and primary teeth with high, low and non-AGP alternatives\nLesion location High AGP* Low AGP* Non-AGP\nCarious lesions limited to enamel\nSmooth surface N/A Resin infiltration Maximise fluoride during tooth brushing\nTopical fluoride therapy\n(Other remineralisation agents**)\nOcclusal surface N/A Resin fissure sealant ART/HVGIC sealant\nGIC sealant\nApproximal surface N/A Resin infiltration Fluoride\n(Other remineralisation agents**)\nCarious lesion extending into dentine or on root surface\nSmooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration\nNRCC\nSDF\nOcclusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration\nNRCC†\nSDF\nApproximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration\nStainless steel crown (conventional placement)\nZirconia crown Resin infiltration (outer 1/3 dentine) ART restoration†\nHall Technique\nNRCC†\nSDF†\nKey:\n* = use rubber dam with sealant around tooth/dam interface and high-volume aspiration\n** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth\n† = only for primary teeth\nART = atraumatic restorative treatment\nCMCR = chemo-mechanical caries removal\nGIC = glass-ionomer cement\nHVGIC = high-viscosity glass-ionomer cement\nNRCC = non-restorative cavity control\nSDF = silver diamine fluoride"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T16","span":{"begin":186,"end":189},"obj":"Chemical"},{"id":"T17","span":{"begin":224,"end":227},"obj":"Chemical"},{"id":"T18","span":{"begin":233,"end":236},"obj":"Chemical"},{"id":"T19","span":{"begin":242,"end":245},"obj":"Chemical"},{"id":"T20","span":{"begin":327,"end":335},"obj":"Chemical"},{"id":"T21","span":{"begin":366,"end":374},"obj":"Chemical"},{"id":"T22","span":{"begin":532,"end":540},"obj":"Chemical"},{"id":"T24","span":{"begin":1051,"end":1056},"obj":"Chemical"},{"id":"T25","span":{"begin":1091,"end":1096},"obj":"Chemical"},{"id":"T26","span":{"begin":1275,"end":1278},"obj":"Chemical"},{"id":"T27","span":{"begin":1279,"end":1282},"obj":"Chemical"},{"id":"T29","span":{"begin":1345,"end":1353},"obj":"Chemical"},{"id":"T30","span":{"begin":1592,"end":1599},"obj":"Chemical"},{"id":"T32","span":{"begin":1636,"end":1643},"obj":"Chemical"},{"id":"T34","span":{"begin":1695,"end":1701},"obj":"Chemical"},{"id":"T36","span":{"begin":1702,"end":1709},"obj":"Chemical"},{"id":"T38","span":{"begin":1710,"end":1718},"obj":"Chemical"}],"attributes":[{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_73349"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_73349"},{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_73349"},{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_73349"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_17051"},{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_17051"},{"id":"A22","pred":"chebi_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_17051"},{"id":"A23","pred":"chebi_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_29228"},{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_37409"},{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_37409"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_34603"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_13534"},{"id":"A28","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_18359"},{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_17051"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_53681"},{"id":"A31","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_61427"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_53681"},{"id":"A33","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_61427"},{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_30512"},{"id":"A35","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_9141"},{"id":"A36","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_15571"},{"id":"A37","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_23666"},{"id":"A38","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_17051"}],"text":"Table 1 Direct restorative procedures (ie not involving a laboratory stage) for managing coronal and root surface carious lesions for permanent and primary teeth with high, low and non-AGP alternatives\nLesion location High AGP* Low AGP* Non-AGP\nCarious lesions limited to enamel\nSmooth surface N/A Resin infiltration Maximise fluoride during tooth brushing\nTopical fluoride therapy\n(Other remineralisation agents**)\nOcclusal surface N/A Resin fissure sealant ART/HVGIC sealant\nGIC sealant\nApproximal surface N/A Resin infiltration Fluoride\n(Other remineralisation agents**)\nCarious lesion extending into dentine or on root surface\nSmooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration\nNRCC\nSDF\nOcclusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration\nNRCC†\nSDF\nApproximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration\nStainless steel crown (conventional placement)\nZirconia crown Resin infiltration (outer 1/3 dentine) ART restoration†\nHall Technique\nNRCC†\nSDF†\nKey:\n* = use rubber dam with sealant around tooth/dam interface and high-volume aspiration\n** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth\n† = only for primary teeth\nART = atraumatic restorative treatment\nCMCR = chemo-mechanical caries removal\nGIC = glass-ionomer cement\nHVGIC = high-viscosity glass-ionomer cement\nNRCC = non-restorative cavity control\nSDF = silver diamine fluoride"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T3","span":{"begin":895,"end":904},"obj":"http://purl.obolibrary.org/obo/GO_0009056"}],"text":"Table 1 Direct restorative procedures (ie not involving a laboratory stage) for managing coronal and root surface carious lesions for permanent and primary teeth with high, low and non-AGP alternatives\nLesion location High AGP* Low AGP* Non-AGP\nCarious lesions limited to enamel\nSmooth surface N/A Resin infiltration Maximise fluoride during tooth brushing\nTopical fluoride therapy\n(Other remineralisation agents**)\nOcclusal surface N/A Resin fissure sealant ART/HVGIC sealant\nGIC sealant\nApproximal surface N/A Resin infiltration Fluoride\n(Other remineralisation agents**)\nCarious lesion extending into dentine or on root surface\nSmooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration\nNRCC\nSDF\nOcclusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration\nNRCC†\nSDF\nApproximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration\nStainless steel crown (conventional placement)\nZirconia crown Resin infiltration (outer 1/3 dentine) ART restoration†\nHall Technique\nNRCC†\nSDF†\nKey:\n* = use rubber dam with sealant around tooth/dam interface and high-volume aspiration\n** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth\n† = only for primary teeth\nART = atraumatic restorative treatment\nCMCR = chemo-mechanical caries removal\nGIC = glass-ionomer cement\nHVGIC = high-viscosity glass-ionomer cement\nNRCC = non-restorative cavity control\nSDF = silver diamine fluoride"}

{"project":"LitCovid-sentences","denotations":[{"id":"T44","span":{"begin":0,"end":202},"obj":"Sentence"},{"id":"T45","span":{"begin":203,"end":245},"obj":"Sentence"},{"id":"T46","span":{"begin":246,"end":279},"obj":"Sentence"},{"id":"T47","span":{"begin":280,"end":357},"obj":"Sentence"},{"id":"T48","span":{"begin":358,"end":382},"obj":"Sentence"},{"id":"T49","span":{"begin":383,"end":416},"obj":"Sentence"},{"id":"T50","span":{"begin":417,"end":477},"obj":"Sentence"},{"id":"T51","span":{"begin":478,"end":489},"obj":"Sentence"},{"id":"T52","span":{"begin":490,"end":540},"obj":"Sentence"},{"id":"T53","span":{"begin":541,"end":574},"obj":"Sentence"},{"id":"T54","span":{"begin":575,"end":631},"obj":"Sentence"},{"id":"T55","span":{"begin":632,"end":752},"obj":"Sentence"},{"id":"T56","span":{"begin":753,"end":757},"obj":"Sentence"},{"id":"T57","span":{"begin":758,"end":761},"obj":"Sentence"},{"id":"T58","span":{"begin":762,"end":921},"obj":"Sentence"},{"id":"T59","span":{"begin":922,"end":927},"obj":"Sentence"},{"id":"T60","span":{"begin":928,"end":931},"obj":"Sentence"},{"id":"T61","span":{"begin":932,"end":1034},"obj":"Sentence"},{"id":"T62","span":{"begin":1035,"end":1081},"obj":"Sentence"},{"id":"T63","span":{"begin":1082,"end":1152},"obj":"Sentence"},{"id":"T64","span":{"begin":1153,"end":1167},"obj":"Sentence"},{"id":"T65","span":{"begin":1168,"end":1173},"obj":"Sentence"},{"id":"T66","span":{"begin":1174,"end":1178},"obj":"Sentence"},{"id":"T67","span":{"begin":1179,"end":1183},"obj":"Sentence"},{"id":"T68","span":{"begin":1184,"end":1269},"obj":"Sentence"},{"id":"T69","span":{"begin":1270,"end":1354},"obj":"Sentence"},{"id":"T70","span":{"begin":1355,"end":1432},"obj":"Sentence"},{"id":"T71","span":{"begin":1433,"end":1474},"obj":"Sentence"},{"id":"T72","span":{"begin":1475,"end":1501},"obj":"Sentence"},{"id":"T73","span":{"begin":1502,"end":1540},"obj":"Sentence"},{"id":"T74","span":{"begin":1541,"end":1579},"obj":"Sentence"},{"id":"T75","span":{"begin":1580,"end":1606},"obj":"Sentence"},{"id":"T76","span":{"begin":1607,"end":1650},"obj":"Sentence"},{"id":"T77","span":{"begin":1651,"end":1688},"obj":"Sentence"},{"id":"T78","span":{"begin":1689,"end":1718},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Table 1 Direct restorative procedures (ie not involving a laboratory stage) for managing coronal and root surface carious lesions for permanent and primary teeth with high, low and non-AGP alternatives\nLesion location High AGP* Low AGP* Non-AGP\nCarious lesions limited to enamel\nSmooth surface N/A Resin infiltration Maximise fluoride during tooth brushing\nTopical fluoride therapy\n(Other remineralisation agents**)\nOcclusal surface N/A Resin fissure sealant ART/HVGIC sealant\nGIC sealant\nApproximal surface N/A Resin infiltration Fluoride\n(Other remineralisation agents**)\nCarious lesion extending into dentine or on root surface\nSmooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration\nNRCC\nSDF\nOcclusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration\nNRCC†\nSDF\nApproximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration\nStainless steel crown (conventional placement)\nZirconia crown Resin infiltration (outer 1/3 dentine) ART restoration†\nHall Technique\nNRCC†\nSDF†\nKey:\n* = use rubber dam with sealant around tooth/dam interface and high-volume aspiration\n** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth\n† = only for primary teeth\nART = atraumatic restorative treatment\nCMCR = chemo-mechanical caries removal\nGIC = glass-ionomer cement\nHVGIC = high-viscosity glass-ionomer cement\nNRCC = non-restorative cavity control\nSDF = silver diamine fluoride"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T9","span":{"begin":1259,"end":1269},"obj":"Phenotype"},{"id":"T10","span":{"begin":1565,"end":1571},"obj":"Phenotype"}],"attributes":[{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0002835"},{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0000670"}],"text":"Table 1 Direct restorative procedures (ie not involving a laboratory stage) for managing coronal and root surface carious lesions for permanent and primary teeth with high, low and non-AGP alternatives\nLesion location High AGP* Low AGP* Non-AGP\nCarious lesions limited to enamel\nSmooth surface N/A Resin infiltration Maximise fluoride during tooth brushing\nTopical fluoride therapy\n(Other remineralisation agents**)\nOcclusal surface N/A Resin fissure sealant ART/HVGIC sealant\nGIC sealant\nApproximal surface N/A Resin infiltration Fluoride\n(Other remineralisation agents**)\nCarious lesion extending into dentine or on root surface\nSmooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration\nNRCC\nSDF\nOcclusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration\nNRCC†\nSDF\nApproximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration\nStainless steel crown (conventional placement)\nZirconia crown Resin infiltration (outer 1/3 dentine) ART restoration†\nHall Technique\nNRCC†\nSDF†\nKey:\n* = use rubber dam with sealant around tooth/dam interface and high-volume aspiration\n** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth\n† = only for primary teeth\nART = atraumatic restorative treatment\nCMCR = chemo-mechanical caries removal\nGIC = glass-ionomer cement\nHVGIC = high-viscosity glass-ionomer cement\nNRCC = non-restorative cavity control\nSDF = silver diamine fluoride"}

{"project":"LitCovid-PubTator","denotations":[{"id":"48","span":{"begin":1695,"end":1709},"obj":"Chemical"},{"id":"49","span":{"begin":246,"end":261},"obj":"Disease"},{"id":"50","span":{"begin":343,"end":365},"obj":"Disease"},{"id":"51","span":{"begin":1565,"end":1583},"obj":"Disease"},{"id":"53","span":{"begin":115,"end":130},"obj":"Disease"}],"attributes":[{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"MESH:D003731"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"MESH:D014076"},{"id":"A51","pred":"tao:has_database_id","subj":"51","obj":"MESH:D003731"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"MESH:D003731"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Table 1 Direct restorative procedures (ie not involving a laboratory stage) for managing coronal and root surface carious lesions for permanent and primary teeth with high, low and non-AGP alternatives\nLesion location High AGP* Low AGP* Non-AGP\nCarious lesions limited to enamel\nSmooth surface N/A Resin infiltration Maximise fluoride during tooth brushing\nTopical fluoride therapy\n(Other remineralisation agents**)\nOcclusal surface N/A Resin fissure sealant ART/HVGIC sealant\nGIC sealant\nApproximal surface N/A Resin infiltration Fluoride\n(Other remineralisation agents**)\nCarious lesion extending into dentine or on root surface\nSmooth or root surface Carious tissue removal (high-speed air rotor) and composite resin restoration N/A ART restoration\nNRCC\nSDF\nOcclusal surface Carious tissue removal (high-speed air rotor) and composite resin restoration Resin fissure sealant (minimal enamel breakdown) ART restoration\nNRCC†\nSDF\nApproximal/multi-surface Carious tissue removal (high-speed air rotor) and composite resin restoration\nStainless steel crown (conventional placement)\nZirconia crown Resin infiltration (outer 1/3 dentine) ART restoration†\nHall Technique\nNRCC†\nSDF†\nKey:\n* = use rubber dam with sealant around tooth/dam interface and high-volume aspiration\n** = CPP-ACP could be used as an additional measure but should not replace fluoride. Peptides may be considered, though there is limited evidence to support them. SDF is not recommended for anterior teeth\n† = only for primary teeth\nART = atraumatic restorative treatment\nCMCR = chemo-mechanical caries removal\nGIC = glass-ionomer cement\nHVGIC = high-viscosity glass-ionomer cement\nNRCC = non-restorative cavity control\nSDF = silver diamine fluoride"}