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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T46","span":{"begin":256,"end":265},"obj":"Body_part"},{"id":"T47","span":{"begin":505,"end":518},"obj":"Body_part"},{"id":"T48","span":{"begin":566,"end":574},"obj":"Body_part"},{"id":"T49","span":{"begin":615,"end":623},"obj":"Body_part"},{"id":"T50","span":{"begin":689,"end":694},"obj":"Body_part"},{"id":"T51","span":{"begin":899,"end":913},"obj":"Body_part"},{"id":"T52","span":{"begin":908,"end":913},"obj":"Body_part"},{"id":"T53","span":{"begin":956,"end":961},"obj":"Body_part"},{"id":"T54","span":{"begin":2267,"end":2274},"obj":"Body_part"},{"id":"T55","span":{"begin":2351,"end":2357},"obj":"Body_part"},{"id":"T56","span":{"begin":2413,"end":2417},"obj":"Body_part"},{"id":"T57","span":{"begin":2769,"end":2786},"obj":"Body_part"},{"id":"T58","span":{"begin":2860,"end":2865},"obj":"Body_part"},{"id":"T59","span":{"begin":2896,"end":2905},"obj":"Body_part"},{"id":"T60","span":{"begin":2932,"end":2937},"obj":"Body_part"}],"attributes":[{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma75150"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma75151"},{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma76576"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma76576"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma12516"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma55631"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma12516"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma314001"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma55628"},{"id":"A55","pred":"fma_id","subj":"T55","obj":"http://purl.org/sig/ont/fma/fma55629"},{"id":"A56","pred":"fma_id","subj":"T56","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A57","pred":"fma_id","subj":"T57","obj":"http://purl.org/sig/ont/fma/fma75151"},{"id":"A58","pred":"fma_id","subj":"T58","obj":"http://purl.org/sig/ont/fma/fma12516"},{"id":"A59","pred":"fma_id","subj":"T59","obj":"http://purl.org/sig/ont/fma/fma75150"},{"id":"A60","pred":"fma_id","subj":"T60","obj":"http://purl.org/sig/ont/fma/fma314001"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T25","span":{"begin":256,"end":265},"obj":"Body_part"},{"id":"T26","span":{"begin":2267,"end":2274},"obj":"Body_part"},{"id":"T27","span":{"begin":2351,"end":2357},"obj":"Body_part"},{"id":"T28","span":{"begin":2413,"end":2417},"obj":"Body_part"},{"id":"T29","span":{"begin":2769,"end":2786},"obj":"Body_part"},{"id":"T30","span":{"begin":2777,"end":2786},"obj":"Body_part"},{"id":"T31","span":{"begin":2896,"end":2905},"obj":"Body_part"}],"attributes":[{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0003672"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0001751"},{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0001752"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0007116"},{"id":"A30","pred":"uberon_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/UBERON_0003672"},{"id":"A31","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0003672"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T29","span":{"begin":2840,"end":2849},"obj":"Disease"},{"id":"T30","span":{"begin":3056,"end":3065},"obj":"Disease"}],"attributes":[{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T63","span":{"begin":16,"end":22},"obj":"http://purl.obolibrary.org/obo/UBERON_0002553"},{"id":"T64","span":{"begin":91,"end":92},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T65","span":{"begin":566,"end":574},"obj":"http://purl.obolibrary.org/obo/UBERON_0002553"},{"id":"T66","span":{"begin":615,"end":623},"obj":"http://purl.obolibrary.org/obo/UBERON_0002553"},{"id":"T67","span":{"begin":624,"end":627},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T68","span":{"begin":633,"end":639},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T69","span":{"begin":820,"end":821},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T70","span":{"begin":979,"end":981},"obj":"http://purl.obolibrary.org/obo/CLO_0004265"},{"id":"T71","span":{"begin":982,"end":984},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T72","span":{"begin":990,"end":993},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T73","span":{"begin":994,"end":995},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T74","span":{"begin":1393,"end":1395},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T75","span":{"begin":1569,"end":1572},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T76","span":{"begin":1751,"end":1752},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T77","span":{"begin":1946,"end":1949},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T78","span":{"begin":2026,"end":2027},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T79","span":{"begin":2136,"end":2137},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T80","span":{"begin":2226,"end":2227},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T81","span":{"begin":2228,"end":2234},"obj":"http://purl.obolibrary.org/obo/UBERON_0002553"},{"id":"T82","span":{"begin":2292,"end":2293},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T83","span":{"begin":2358,"end":2361},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T84","span":{"begin":2400,"end":2411},"obj":"http://purl.obolibrary.org/obo/OBI_0000968"},{"id":"T85","span":{"begin":2418,"end":2429},"obj":"http://purl.obolibrary.org/obo/OBI_0000968"},{"id":"T86","span":{"begin":2511,"end":2512},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T87","span":{"begin":2554,"end":2562},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T88","span":{"begin":2687,"end":2693},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T89","span":{"begin":2741,"end":2749},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T73","span":{"begin":1017,"end":1021},"obj":"Chemical"},{"id":"T74","span":{"begin":1401,"end":1404},"obj":"Chemical"},{"id":"T75","span":{"begin":2516,"end":2519},"obj":"Chemical"}],"attributes":[{"id":"A73","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_22695"},{"id":"A74","pred":"chebi_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/CHEBI_73349"},{"id":"A75","pred":"chebi_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/CHEBI_28741"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}

    LitCovid-PD-GO-BP

    {"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T6","span":{"begin":1376,"end":1385},"obj":"http://purl.obolibrary.org/obo/GO_0007610"},{"id":"T7","span":{"begin":1595,"end":1605},"obj":"http://purl.obolibrary.org/obo/GO_0007610"},{"id":"T8","span":{"begin":1774,"end":1783},"obj":"http://purl.obolibrary.org/obo/GO_0007610"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T141","span":{"begin":0,"end":51},"obj":"Sentence"},{"id":"T142","span":{"begin":53,"end":82},"obj":"Sentence"},{"id":"T143","span":{"begin":83,"end":182},"obj":"Sentence"},{"id":"T144","span":{"begin":183,"end":333},"obj":"Sentence"},{"id":"T145","span":{"begin":335,"end":374},"obj":"Sentence"},{"id":"T146","span":{"begin":375,"end":501},"obj":"Sentence"},{"id":"T147","span":{"begin":502,"end":1210},"obj":"Sentence"},{"id":"T148","span":{"begin":1211,"end":1395},"obj":"Sentence"},{"id":"T149","span":{"begin":1397,"end":1408},"obj":"Sentence"},{"id":"T150","span":{"begin":1409,"end":1556},"obj":"Sentence"},{"id":"T151","span":{"begin":1557,"end":1664},"obj":"Sentence"},{"id":"T152","span":{"begin":1665,"end":1814},"obj":"Sentence"},{"id":"T153","span":{"begin":1815,"end":2075},"obj":"Sentence"},{"id":"T154","span":{"begin":2076,"end":2216},"obj":"Sentence"},{"id":"T155","span":{"begin":2217,"end":2323},"obj":"Sentence"},{"id":"T156","span":{"begin":2324,"end":2376},"obj":"Sentence"},{"id":"T157","span":{"begin":2377,"end":2480},"obj":"Sentence"},{"id":"T158","span":{"begin":2481,"end":2761},"obj":"Sentence"},{"id":"T159","span":{"begin":2762,"end":2877},"obj":"Sentence"},{"id":"T160","span":{"begin":2878,"end":3123},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T20","span":{"begin":246,"end":265},"obj":"Phenotype"},{"id":"T21","span":{"begin":2828,"end":2832},"obj":"Phenotype"},{"id":"T22","span":{"begin":2886,"end":2905},"obj":"Phenotype"},{"id":"T23","span":{"begin":3044,"end":3048},"obj":"Phenotype"}],"attributes":[{"id":"A20","pred":"hp_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/HP_0008498"},{"id":"A21","pred":"hp_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/HP_0012531"},{"id":"A22","pred":"hp_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/HP_0008498"},{"id":"A23","pred":"hp_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/HP_0012531"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"111","span":{"begin":35,"end":51},"obj":"Disease"},{"id":"115","span":{"begin":154,"end":169},"obj":"Disease"},{"id":"116","span":{"begin":202,"end":226},"obj":"Disease"},{"id":"117","span":{"begin":272,"end":287},"obj":"Disease"},{"id":"119","span":{"begin":494,"end":500},"obj":"Disease"},{"id":"121","span":{"begin":1317,"end":1324},"obj":"Species"},{"id":"123","span":{"begin":1401,"end":1404},"obj":"Chemical"},{"id":"129","span":{"begin":1467,"end":1474},"obj":"Species"},{"id":"130","span":{"begin":1561,"end":1568},"obj":"Species"},{"id":"131","span":{"begin":1722,"end":1729},"obj":"Species"},{"id":"132","span":{"begin":1753,"end":1758},"obj":"Species"},{"id":"133","span":{"begin":1989,"end":1996},"obj":"Species"},{"id":"138","span":{"begin":2516,"end":2519},"obj":"Gene"},{"id":"139","span":{"begin":2500,"end":2503},"obj":"Chemical"},{"id":"140","span":{"begin":2669,"end":2683},"obj":"Disease"},{"id":"141","span":{"begin":2726,"end":2740},"obj":"Disease"},{"id":"147","span":{"begin":2828,"end":2832},"obj":"Disease"},{"id":"148","span":{"begin":2840,"end":2849},"obj":"Disease"},{"id":"149","span":{"begin":2944,"end":2959},"obj":"Disease"},{"id":"150","span":{"begin":3044,"end":3048},"obj":"Disease"},{"id":"151","span":{"begin":3056,"end":3065},"obj":"Disease"}],"attributes":[{"id":"A111","pred":"tao:has_database_id","subj":"111","obj":"MESH:D003805"},{"id":"A115","pred":"tao:has_database_id","subj":"115","obj":"MESH:D003731"},{"id":"A116","pred":"tao:has_database_id","subj":"116","obj":"MESH:D003731"},{"id":"A117","pred":"tao:has_database_id","subj":"117","obj":"MESH:D003731"},{"id":"A119","pred":"tao:has_database_id","subj":"119","obj":"MESH:D006323"},{"id":"A121","pred":"tao:has_database_id","subj":"121","obj":"Tax:9606"},{"id":"A129","pred":"tao:has_database_id","subj":"129","obj":"Tax:9606"},{"id":"A130","pred":"tao:has_database_id","subj":"130","obj":"Tax:9606"},{"id":"A131","pred":"tao:has_database_id","subj":"131","obj":"Tax:9606"},{"id":"A132","pred":"tao:has_database_id","subj":"132","obj":"Tax:9606"},{"id":"A133","pred":"tao:has_database_id","subj":"133","obj":"Tax:9606"},{"id":"A138","pred":"tao:has_database_id","subj":"138","obj":"Gene:3576"},{"id":"A139","pred":"tao:has_database_id","subj":"139","obj":"MESH:C024633"},{"id":"A140","pred":"tao:has_database_id","subj":"140","obj":"MESH:D003731"},{"id":"A141","pred":"tao:has_database_id","subj":"141","obj":"MESH:D003731"},{"id":"A147","pred":"tao:has_database_id","subj":"147","obj":"MESH:D010146"},{"id":"A148","pred":"tao:has_database_id","subj":"148","obj":"MESH:D007239"},{"id":"A149","pred":"tao:has_database_id","subj":"149","obj":"MESH:D003731"},{"id":"A150","pred":"tao:has_database_id","subj":"150","obj":"MESH:D010146"},{"id":"A151","pred":"tao:has_database_id","subj":"151","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Non-restorative cavity control for dentinal lesions\n\nWhat it is and when to use it\nNRCC is a method of using 'cleaning' to prevent biofilm maturation and carious lesions progression. It can be used for dentinal carious lesions in the primary and permanent dentition, root carious lesions and cavitated coronal smooth surface lesions.\n\nHow it works and clinical effectiveness\nBy making the carious surface accessible and having plaque frequently and thoroughly removed, the carious process will arrest.\nIn primary teeth, the effectiveness of NRCC in medium and large cavities together with ART restorations in small cavities has been tested in comparison to amalgam and ART restorations.33 Tooth survival after 3.5 years was 89% and not significantly different from either amalgam (91%) or ART restorations (90%), and in a randomised control trial of occluso-proximal cavitated lesions, survival (of pulp and tooth) was 92% at 2.5 years compared to 98% for teeth treated with the HT.34 NRCC has a less robust evidence base than the other treatment options discussed in this paper, with most of the reports of success being related to particular situations and carried out by dentists who support this technique. The choice to use NRCC is less dependent on the shape or type of lesion than it is on the attitude of the patient towards prevention and the skill of the dentist in behaviour change.35\n\nNon-AGP use\nNRCC consists of three concurrent stages:Working with the patient to make plaque control more successful (improving oral hygiene procedure/habits). The patient has to be ready to change behaviours that led to development of the disease in the first place. Success depends on the clinician's ability to change the patient's (or in the case of a child, the parent's) behaviour towards taking responsibility. So, 'prevention' becomes very much more than simply providing instruction of what to do (knowledge) and how to do it (skills), but has to involve an aspect of refocusing the patient to feeling empowered to make a difference to their own oral health (attitude). Daily removal or disruption of the biofilm by brushing with a fluoridated toothpaste will slow down the carious process and can even halt it\nCreating a cavity shape where the carious biofilm/dentine is accessible to a toothbrush (lesion exposure). In some cases, overhanging enamel has to be removed. To avoid use of rotary instruments, hand instruments can be used to gain access to the lesion (see ART)\nTreatment with 38% SDF and/or a 5% NaF varnish therapy to reduce carious activity and promote remineralisation.33 These additional measures can support success of the NRCC approach if the carious lesion is active or there is increased risk that carious lesion activity will recur.\nIn the primary dentition, the goal is to avoid the lesion causing pain and/or infection until the tooth exfoliates. For the permanent dentition, with grossly broken down teeth, root carious lesions or coronal smooth surface lesions, the main goal is to avoid the lesions leading to pain and/or infection while also avoiding or delaying the need for restoration."}