PMC:7546139 / 11375-12565 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T39","span":{"begin":152,"end":158},"obj":"Body_part"},{"id":"T40","span":{"begin":334,"end":339},"obj":"Body_part"},{"id":"T41","span":{"begin":733,"end":750},"obj":"Body_part"},{"id":"T42","span":{"begin":1011,"end":1017},"obj":"Body_part"},{"id":"T43","span":{"begin":1073,"end":1077},"obj":"Body_part"}],"attributes":[{"id":"A39","pred":"fma_id","subj":"T39","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A40","pred":"fma_id","subj":"T40","obj":"http://purl.org/sig/ont/fma/fma82737"},{"id":"A41","pred":"fma_id","subj":"T41","obj":"http://purl.org/sig/ont/fma/fma75113"},{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma55630"},{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma9712"}],"text":"Prevention\nPrimary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments. The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education. Clinicians hold a pivotal role in supporting oral health behaviours.\nFor remineralisation, fluoride-based agents are accepted as the primary medicament. Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.\nPreventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol. Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments. A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T23","span":{"begin":152,"end":158},"obj":"Body_part"},{"id":"T24","span":{"begin":1073,"end":1077},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"}],"text":"Prevention\nPrimary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments. The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education. Clinicians hold a pivotal role in supporting oral health behaviours.\nFor remineralisation, fluoride-based agents are accepted as the primary medicament. Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.\nPreventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol. Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments. A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T56","span":{"begin":211,"end":222},"obj":"http://purl.obolibrary.org/obo/OBI_0000968"},{"id":"T57","span":{"begin":411,"end":412},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T58","span":{"begin":646,"end":653},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T59","span":{"begin":841,"end":842},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T60","span":{"begin":1078,"end":1089},"obj":"http://purl.obolibrary.org/obo/OBI_0000968"},{"id":"T61","span":{"begin":1091,"end":1092},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Prevention\nPrimary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments. The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education. Clinicians hold a pivotal role in supporting oral health behaviours.\nFor remineralisation, fluoride-based agents are accepted as the primary medicament. Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.\nPreventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol. Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments. A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T67","span":{"begin":486,"end":494},"obj":"Chemical"},{"id":"T68","span":{"begin":536,"end":546},"obj":"Chemical"},{"id":"T69","span":{"begin":646,"end":653},"obj":"Chemical"},{"id":"T70","span":{"begin":870,"end":874},"obj":"Chemical"},{"id":"T71","span":{"begin":1003,"end":1010},"obj":"Chemical"}],"attributes":[{"id":"A67","pred":"chebi_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/CHEBI_17051"},{"id":"A68","pred":"chebi_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_52217"},{"id":"A69","pred":"chebi_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A70","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A71","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_53681"},{"id":"A72","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_61427"}],"text":"Prevention\nPrimary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments. The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education. Clinicians hold a pivotal role in supporting oral health behaviours.\nFor remineralisation, fluoride-based agents are accepted as the primary medicament. Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.\nPreventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol. Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments. A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T4","span":{"begin":303,"end":314},"obj":"http://purl.obolibrary.org/obo/GO_0007610"},{"id":"T5","span":{"begin":452,"end":462},"obj":"http://purl.obolibrary.org/obo/GO_0007610"}],"text":"Prevention\nPrimary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments. The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education. Clinicians hold a pivotal role in supporting oral health behaviours.\nFor remineralisation, fluoride-based agents are accepted as the primary medicament. Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.\nPreventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol. Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments. A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30"}

{"project":"LitCovid-sentences","denotations":[{"id":"T128","span":{"begin":0,"end":10},"obj":"Sentence"},{"id":"T129","span":{"begin":11,"end":223},"obj":"Sentence"},{"id":"T130","span":{"begin":224,"end":394},"obj":"Sentence"},{"id":"T131","span":{"begin":395,"end":463},"obj":"Sentence"},{"id":"T132","span":{"begin":464,"end":547},"obj":"Sentence"},{"id":"T133","span":{"begin":548,"end":682},"obj":"Sentence"},{"id":"T134","span":{"begin":683,"end":916},"obj":"Sentence"},{"id":"T135","span":{"begin":917,"end":1090},"obj":"Sentence"},{"id":"T136","span":{"begin":1091,"end":1190},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Prevention\nPrimary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments. The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education. Clinicians hold a pivotal role in supporting oral health behaviours.\nFor remineralisation, fluoride-based agents are accepted as the primary medicament. Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.\nPreventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol. Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments. A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T16","span":{"begin":102,"end":108},"obj":"Phenotype"},{"id":"T17","span":{"begin":790,"end":796},"obj":"Phenotype"}],"attributes":[{"id":"A16","pred":"hp_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/HP_0000670"},{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0000670"}],"text":"Prevention\nPrimary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments. The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education. Clinicians hold a pivotal role in supporting oral health behaviours.\nFor remineralisation, fluoride-based agents are accepted as the primary medicament. Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.\nPreventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol. Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments. A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30"}

{"project":"LitCovid-PubTator","denotations":[{"id":"103","span":{"begin":486,"end":494},"obj":"Chemical"},{"id":"105","span":{"begin":755,"end":759},"obj":"Disease"}],"attributes":[{"id":"A103","pred":"tao:has_database_id","subj":"103","obj":"MESH:D005459"},{"id":"A105","pred":"tao:has_database_id","subj":"105","obj":"MESH:C536528"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Prevention\nPrimary preventive approaches (also known as non-invasive strategies for the management of caries) can reduce the risk of progressive dental tissue loss and avoid the need for treatments using rotary instruments. The main preventive approaches have to be through the community and home, with behavioural components such as sugar restriction, plaque removal and oral health education. Clinicians hold a pivotal role in supporting oral health behaviours.\nFor remineralisation, fluoride-based agents are accepted as the primary medicament. Although there is less supporting evidence, other remineralisation agents such as self-assembling peptide P11-428 might be considered.\nPreventive sealants cover plaque-retentive areas, occlusal fissures and pits, which are most vulnerable to caries.29,30 However, resin-based sealants involve a washing step to remove the acid etch thoroughly, generating some aerosol. Nevertheless, this risk can be avoided by using low-viscosity or high-viscosity glass-ionomer cement (LVGICS/HVGIC) and excess material can be removed with hand instruments. A Cochrane review found no difference in the preventive effect of resin, LVGIC or HVGIC sealants.30"}