PMC:7546130 / 9616-10715
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T61 | 26-29 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T62 | 48-51 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T63 | 121-129 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T64 | 156-159 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T65 | 277-298 | Body_part | denotes | capillary endothelium | http://purl.org/sig/ont/fma/fma62114 |
| T66 | 306-311 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
| T67 | 312-317 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T68 | 434-437 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T69 | 445-448 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T70 | 606-609 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T71 | 669-674 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T72 | 675-680 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
| T73 | 867-872 | Body_part | denotes | organ | http://purl.org/sig/ont/fma/fma67498 |
| T74 | 991-994 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T46 | 277-286 | Body_part | denotes | capillary | http://purl.obolibrary.org/obo/UBERON_0001982 |
| T47 | 287-298 | Body_part | denotes | endothelium | http://purl.obolibrary.org/obo/UBERON_0001986 |
| T48 | 306-311 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T49 | 312-317 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T50 | 669-688 | Body_part | denotes | blood brain barrier | http://purl.obolibrary.org/obo/UBERON_0000120 |
| T51 | 669-674 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T52 | 675-680 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T53 | 867-872 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T49 | 15-23 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T50 | 364-372 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T51 | 826-838 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T52 | 858-880 | Disease | denotes | multiple organ failure | http://purl.obolibrary.org/obo/MONDO_0043726 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T77 | 79-80 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T78 | 102-107 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T79 | 197-200 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T80 | 229-234 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T81 | 287-298 | http://purl.obolibrary.org/obo/UBERON_0001986 | denotes | endothelium |
| T82 | 306-311 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
| T83 | 306-311 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
| T84 | 312-317 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T85 | 312-317 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T86 | 518-520 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T87 | 526-527 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T88 | 669-674 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T89 | 669-674 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T90 | 675-680 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
| T91 | 675-680 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
| T92 | 791-792 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T93 | 843-844 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T94 | 867-872 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organ |
| T95 | 961-962 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T96 | 978-983 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T97 | 1080-1081 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T98 | 1095-1097 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T31 | 121-129 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T10 | 826-838 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T11 | 937-946 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | breakdown |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T79 | 0-78 | Sentence | denotes | The meaning of SARS-CoV-2 RNA positivity in the CSF of our patient is unclear. |
| T80 | 79-177 | Sentence | denotes | A direct effect of the virus, with normal proteins and no pleocytosis in the CSF, is questionable. |
| T81 | 178-522 | Sentence | denotes | Viral neurotropism has been largely theorized, and virus particles have been observed to cross the capillary endothelium of the brain blood barrier (BBB) [10], but direct implication of SARS-CoV-2 in neurological manifestations is controversial, and viral RNA in the CSF of patients with neurological complications is only rarely detected [11]. |
| T82 | 523-710 | Sentence | denotes | In a recent study including 31 patients with neurological manifestations, none had CSF viral positivity, but many had signs of disturbance of the blood brain barrier (BBB) integrity [12]. |
| T83 | 711-881 | Sentence | denotes | Our patient showed signs of mild damage of the BBB as well, which might also be a possible consequence of systemic inflammation, in a patient with multiple organ failure. |
| T84 | 882-1039 | Sentence | denotes | Therefore, an indirect mechanism of neurovascular unit breakdown, resulting in a passage of the virus in the CSF through the damaged BBB, cannot be excluded. |
| T85 | 1040-1099 | Sentence | denotes | Contamination or artifact could also be a possibility [11]. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 226 | 15-25 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 227 | 59-66 | Species | denotes | patient | Tax:9606 |
| 228 | 364-374 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 229 | 452-460 | Species | denotes | patients | Tax:9606 |
| 230 | 554-562 | Species | denotes | patients | Tax:9606 |
| 231 | 715-722 | Species | denotes | patient | Tax:9606 |
| 232 | 845-852 | Species | denotes | patient | Tax:9606 |
| 233 | 178-196 | Disease | denotes | Viral neurotropism | |
| 234 | 466-492 | Disease | denotes | neurological complications | MESH:D002493 |
| 235 | 650-680 | Disease | denotes | disturbance of the blood brain | MESH:D007022 |
| 236 | 826-838 | Disease | denotes | inflammation | MESH:D007249 |
| 237 | 858-880 | Disease | denotes | multiple organ failure | MESH:D009102 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 33034804-32314810-75886974 | 333-335 | 32314810 | denotes | 10 |
| 33034804-32882182-75886975 | 518-520 | 32882182 | denotes | 11 |
| 33034804-32882182-75886976 | 1095-1097 | 32882182 | denotes | 11 |