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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7546130","sourcedb":"PMC","sourceid":"7546130","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7546130","text":"olving microvessels. The underlying mechanisms, which include direct and indirect penetration of the virus to the central nervous system and systemic cardiorespiratory complications, are yet to be elucidated, and a direct correlation with SARS-CoV-2 infection remains uncertain.\n\nIntroduction\nNeurological manifestations have been observed in a relevant proportion of patients with COVID-19 [1] with different magnetic resonance imaging (MRI) patterns [2]. We report the case of a patient with severe neurological complications and brain MRI evidence of multiple supratentorial areas of restricted diffusion at diffusion-weighted imaging (DWI), consistent with acute 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