PMC:7544943 / 32521-33299
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T44 | 81-88 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T45 | 164-171 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T157 | 231-232 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T158 | 326-327 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 763 | 18-26 | Chemical | denotes | hydrogen | MESH:D006859 |
| 776 | 196-200 | Gene | denotes | Mpro | Gene:8673700 |
| 777 | 546-550 | Gene | denotes | Mpro | Gene:8673700 |
| 778 | 415-419 | Gene | denotes | Mpro | Gene:8673700 |
| 779 | 47-55 | Chemical | denotes | hydrogen | MESH:D006859 |
| 780 | 217-225 | Chemical | denotes | Piperine | MESH:C008922 |
| 781 | 256-264 | Chemical | denotes | hydrogen | MESH:D006859 |
| 782 | 354-362 | Chemical | denotes | hydrogen | MESH:D006859 |
| 783 | 397-410 | Chemical | denotes | Spro-Piperine | |
| 784 | 458-466 | Chemical | denotes | hydrogen | MESH:D006859 |
| 785 | 524-527 | Chemical | denotes | RBD | |
| 786 | 528-541 | Chemical | denotes | Spro-Piperine | |
| 787 | 681-689 | Chemical | denotes | hydrogen | MESH:D006859 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T282 | 0-6 | Sentence | denotes | 3.6.4. |
| T283 | 8-32 | Sentence | denotes | Number of hydrogen bonds |
| T284 | 33-172 | Sentence | denotes | The number of hydrogen bonds formed between the protein–ligand complex is the measure of the binding strength of the ligand to the protein. |
| T285 | 173-316 | Sentence | denotes | The RBD Spro (red) and Mpro (blue) bound to Piperine have a constant number of 1–2 hydrogen bonds throughout the simulation time (Figure 7(c)). |
| T286 | 317-443 | Sentence | denotes | There is a maximum number of 3 and 4 hydrogen bonds observed in the case of RBD Spro-Piperine and Mpro-Piperine, respectively. |
| T287 | 444-659 | Sentence | denotes | The number of hydrogen bonds fluctuates throughout the simulation time for both RBD Spro-Piperine and Mpro-Piperine, which suggests for conformational changes in the binding site of the ligand during the simulation. |
| T288 | 660-778 | Sentence | denotes | The observation from hydrogen bond analysis indicates that the complexes are stable for the performed simulation time. |