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PMC:7544943 / 30370-31312 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T34 39-47 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T35 172-180 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T36 226-234 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T37 735-742 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T139 226-252 http://purl.obolibrary.org/obo/GO_0043234 denotes proteins and their complex
T140 544-545 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T141 576-577 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T142 717-718 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T143 735-751 http://purl.obolibrary.org/obo/CHEBI_33708 denotes protein residues
T144 880-886 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T145 908-909 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
721 639-643 Gene denotes Mpro Gene:8673700
722 552-556 Gene denotes Mpro Gene:8673700
723 364-368 Gene denotes Mpro Gene:8673700
724 355-359 Gene denotes Mpro Gene:8673700
725 61-65 Gene denotes Mpro Gene:8673700
726 154-162 Chemical denotes Piperine MESH:C008922
727 258-266 Chemical denotes Piperine MESH:C008922
728 340-353 Chemical denotes Spro-Piperine
729 520-533 Chemical denotes Spro-Piperine
730 831-839 Chemical denotes Piperine MESH:C008922
731 898-906 Chemical denotes Piperine MESH:C008922

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T265 0-181 Sentence denotes The conformational fluctuations of the proteins RBD Spro and Mpro were analysed by observing the residual changes that resulted due to the interaction of Piperine with the proteins.
T266 182-289 Sentence denotes The RMSF plots of the Cα atoms of the viral proteins and their complex with Piperine are shown in Figure 6.
T267 290-495 Sentence denotes From the analysis, it is found that RBD Spro, RBD Spro-Piperine, Mpro and Mpro-Piperine have the average RMSF values 0.099 ± 0.060 nm, 0.097 ± 0.051 nm, 0.119 ± 0.077 nm and 0.120 ± 0.077 nm, respectively.
T268 496-695 Sentence denotes It is observed that RBD Spro-Piperine (Figure 6(a)) and Mpro-Piperine (Figure 6(b)) show similar fluctuations as compared to only RBD Spro and Mpro, which implies to the stability of these compounds.
T269 696-798 Sentence denotes In addition to that, a majority of the protein residues are found to be stabilized within RMSF 0.3 nm.
T270 799-910 Sentence denotes The decrease in fluctuations of Piperine bound to RBD Spro also suggests for the active binding of Piperine (A.
T271 911-942 Sentence denotes Kumar, Choudhir, et al., 2020).