
PMC:7544943 / 30370-31312
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T34 | 39-47 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T35 | 172-180 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T36 | 226-234 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T37 | 735-742 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T139 | 226-252 | http://purl.obolibrary.org/obo/GO_0043234 | denotes | proteins and their complex |
T140 | 544-545 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T141 | 576-577 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T142 | 717-718 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T143 | 735-751 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | protein residues |
T144 | 880-886 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
T145 | 908-909 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
721 | 639-643 | Gene | denotes | Mpro | Gene:8673700 |
722 | 552-556 | Gene | denotes | Mpro | Gene:8673700 |
723 | 364-368 | Gene | denotes | Mpro | Gene:8673700 |
724 | 355-359 | Gene | denotes | Mpro | Gene:8673700 |
725 | 61-65 | Gene | denotes | Mpro | Gene:8673700 |
726 | 154-162 | Chemical | denotes | Piperine | MESH:C008922 |
727 | 258-266 | Chemical | denotes | Piperine | MESH:C008922 |
728 | 340-353 | Chemical | denotes | Spro-Piperine | |
729 | 520-533 | Chemical | denotes | Spro-Piperine | |
730 | 831-839 | Chemical | denotes | Piperine | MESH:C008922 |
731 | 898-906 | Chemical | denotes | Piperine | MESH:C008922 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T265 | 0-181 | Sentence | denotes | The conformational fluctuations of the proteins RBD Spro and Mpro were analysed by observing the residual changes that resulted due to the interaction of Piperine with the proteins. |
T266 | 182-289 | Sentence | denotes | The RMSF plots of the Cα atoms of the viral proteins and their complex with Piperine are shown in Figure 6. |
T267 | 290-495 | Sentence | denotes | From the analysis, it is found that RBD Spro, RBD Spro-Piperine, Mpro and Mpro-Piperine have the average RMSF values 0.099 ± 0.060 nm, 0.097 ± 0.051 nm, 0.119 ± 0.077 nm and 0.120 ± 0.077 nm, respectively. |
T268 | 496-695 | Sentence | denotes | It is observed that RBD Spro-Piperine (Figure 6(a)) and Mpro-Piperine (Figure 6(b)) show similar fluctuations as compared to only RBD Spro and Mpro, which implies to the stability of these compounds. |
T269 | 696-798 | Sentence | denotes | In addition to that, a majority of the protein residues are found to be stabilized within RMSF 0.3 nm. |
T270 | 799-910 | Sentence | denotes | The decrease in fluctuations of Piperine bound to RBD Spro also suggests for the active binding of Piperine (A. |
T271 | 911-942 | Sentence | denotes | Kumar, Choudhir, et al., 2020). |