PMC:7544943 / 29312-30324
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T30 | 168-176 | Body_part | denotes | backbone | http://purl.org/sig/ont/fma/fma13478 |
| T31 | 196-204 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T32 | 580-588 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T33 | 609-617 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T132 | 63-65 | http://purl.obolibrary.org/obo/CLO_0007622 | denotes | MD |
| T133 | 196-222 | http://purl.obolibrary.org/obo/GO_0043234 | denotes | proteins and their complex |
| T134 | 762-763 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T135 | 839-843 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T136 | 866-870 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T137 | 921-922 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T138 | 971-972 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 699 | 404-408 | Gene | denotes | Mpro | Gene:8673700 |
| 700 | 413-417 | Gene | denotes | Mpro | Gene:8673700 |
| 701 | 228-236 | Chemical | denotes | Piperine | MESH:C008922 |
| 702 | 389-402 | Chemical | denotes | Spro-Piperine | |
| 703 | 565-573 | Chemical | denotes | Piperine | MESH:C008922 |
| 707 | 974-978 | Gene | denotes | Mpro | Gene:8673700 |
| 708 | 991-995 | Gene | denotes | Mpro | Gene:8673700 |
| 709 | 949-962 | Chemical | denotes | Spro-Piperine |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T253 | 0-6 | Sentence | denotes | 3.6.1. |
| T254 | 8-41 | Sentence | denotes | Root mean square deviation (RMSD) |
| T255 | 42-143 | Sentence | denotes | The RMSD values from MD simulation provide information about structural and conformational stability. |
| T256 | 144-237 | Sentence | denotes | Figure 5 represents the backbone RMSD data of viral proteins and their complex with Piperine. |
| T257 | 238-347 | Sentence | denotes | From the plot, it is observed that both the simulations have less fluctuation throughout the simulation time. |
| T258 | 348-533 | Sentence | denotes | The average RMSD values of RBD Spro, RBD Spro-Piperine, Mpro and Mpro-Piperine are calculated as 0.143 ± 0.025 nm, 0.130 ± 0.018 nm, 0.212 ± 0.041 nm and 0.203 ± 0.028 nm, respectively. |
| T259 | 534-686 | Sentence | denotes | The average RMSD values of the Piperine bound proteins as compared to only proteins are found to be less representing to their conformational stability. |
| T260 | 687-872 | Sentence | denotes | Both the simulations are attained equilibrium within 0.3 nm, which is also a measure of the systems’ stability during the simulation (Al-Shabib et al., 2018, 2020; Millan et al., 2018). |
| T261 | 873-882 | Sentence | denotes | Figure 5. |
| T262 | 884-1012 | Sentence | denotes | Root mean square deviation plots of (a) RBD Spro (black) and RBD Spro-Piperine (red); (b) Mpro (black) and Mpro-Piperine (blue). |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32938313-32194324-56197396 | 845-849 | 32194324 | denotes | 2020 |