PMC:7544943 / 18906-19546 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7544943","sourcedb":"PMC","sourceid":"7544943","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7544943","text":"Predicted lipophilicity (Log P) values of the spice molecules obtained from different calculation models are shown in Figure 1. All the molecules subjected to lipophilicity test lie in the range of +1.2 to +4.19 of consensus value that obeys the Lipinski’s limit of log p \u003c 5, which suggests they can be used for further clinical trials (Arnott \u0026 Planey, 2012). The lowest lipophilicity is observed for Vanillin and the highest for Nerolidol, among the screened molecules. From Figure 1, it is found that all the ligand molecules have positive lipophilicity value. Hence, these molecules satisfy the essential criteria to be drug molecules.","tracks":[{"project":"LitCovid-PD-CLO","denotations":[{"id":"T86","span":{"begin":173,"end":177},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"attributes":[{"subj":"T86","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"290","span":{"begin":403,"end":411},"obj":"Chemical"},{"id":"291","span":{"begin":432,"end":441},"obj":"Chemical"}],"attributes":[{"id":"A290","pred":"tao:has_database_id","subj":"290","obj":"MESH:C100058"},{"id":"A291","pred":"tao:has_database_id","subj":"291","obj":"MESH:C037055"},{"subj":"290","pred":"source","obj":"LitCovid-PubTator"},{"subj":"291","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T171","span":{"begin":0,"end":127},"obj":"Sentence"},{"id":"T172","span":{"begin":128,"end":361},"obj":"Sentence"},{"id":"T173","span":{"begin":362,"end":472},"obj":"Sentence"},{"id":"T174","span":{"begin":473,"end":564},"obj":"Sentence"},{"id":"T175","span":{"begin":565,"end":640},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T171","pred":"source","obj":"LitCovid-sentences"},{"subj":"T172","pred":"source","obj":"LitCovid-sentences"},{"subj":"T173","pred":"source","obj":"LitCovid-sentences"},{"subj":"T174","pred":"source","obj":"LitCovid-sentences"},{"subj":"T175","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32938313-22992175-56197389","span":{"begin":355,"end":359},"obj":"22992175"}],"attributes":[{"subj":"32938313-22992175-56197389","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-CLO","color":"#93b7ec","default":true},{"id":"LitCovid-PubTator","color":"#d1ec93"},{"id":"LitCovid-sentences","color":"#ec93eb"},{"id":"2_test","color":"#93ecd3"}]}]}}