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LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 68-76 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 77-85 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T3 128-152 Disease denotes Coronavirus Disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T4 154-162 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 174-183 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 444-454 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T7 789-797 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 1436-1444 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 1493-1501 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 167-168 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 202-203 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 305-313 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T4 423-424 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T5 572-573 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 623-624 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 907-908 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 1025-1033 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T9 1101-1102 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 1264-1265 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 39-49 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T2 295-304 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T3 922-928 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T4 1054-1064 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T5 1359-1377 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T6 1381-1400 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T7 1381-1390 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T8 1391-1400 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T9 1411-1430 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T11 1420-1430 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T12 1681-1691 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 54-62 Species denotes children Tax:9606
3 68-76 Disease denotes COVID-19 MESH:C000657245
9 192-200 Species denotes children Tax:9606
10 404-412 Species denotes children Tax:9606
11 128-152 Disease denotes Coronavirus Disease 2019 MESH:C000657245
12 154-162 Disease denotes COVID-19 MESH:C000657245
13 174-183 Disease denotes infection MESH:D007239
15 444-463 Disease denotes infectious diseases MESH:D003141
29 801-809 Species denotes children Tax:9606
30 866-874 Species denotes children Tax:9606
31 1188-1196 Species denotes children Tax:9606
32 1309-1317 Species denotes patients Tax:9606
33 1448-1456 Species denotes children Tax:9606
34 922-928 Chemical denotes oxygen MESH:D010100
35 1054-1064 Chemical denotes remdesivir MESH:C000606551
36 1132-1142 Chemical denotes Remdesivir MESH:C000606551
37 1359-1377 Chemical denotes hydroxychloroquine MESH:D006886
38 1381-1400 Chemical denotes lopinavir-ritonavir MESH:C558899
39 789-797 Disease denotes COVID-19 MESH:C000657245
40 1173-1187 Disease denotes critically ill MESH:D016638
41 1436-1444 Disease denotes COVID-19 MESH:C000657245
46 1555-1563 Species denotes patients Tax:9606
47 1569-1577 Species denotes children Tax:9606
48 1681-1691 Chemical denotes remdesivir MESH:C000606551
49 1493-1501 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-87 Sentence denotes Multicenter interim guidance on use of antivirals for children with COVID-19/SARS-CoV-2
T2 89-97 Sentence denotes Abstract
T3 98-106 Sentence denotes Abstract
T4 108-118 Sentence denotes Background
T5 119-256 Sentence denotes Although Coronavirus Disease 2019 (COVID-19) is a mild infection in most children, a small proportion develop severe or critical illness.
T6 257-413 Sentence denotes Data evaluating agents with potential antiviral activity continue to expand, such that updated guidance is needed regarding use of these agents in children.
T7 415-422 Sentence denotes Methods
T8 423-563 Sentence denotes A panel of pediatric infectious diseases physicians and pharmacists from 20 geographically diverse North American institutions was convened.
T9 564-744 Sentence denotes Through a series of teleconferences and web-based surveys, a set of guidance statements was developed and refined based on review of the best available evidence and expert opinion.
T10 746-753 Sentence denotes Results
T11 754-861 Sentence denotes Given the typically mild course of COVID-19 in children, supportive care alone is suggested for most cases.
T12 862-1131 Sentence denotes For children with severe illness, defined as a supplemental oxygen requirement without need for non-invasive or invasive mechanical ventilation or extra-corporeal membrane oxygenation (ECMO), remdesivir is suggested, preferably as part of a clinical trial if available.
T13 1132-1263 Sentence denotes Remdesivir should also be considered for critically ill children requiring invasive or non-invasive mechanical ventilation or ECMO.
T14 1264-1318 Sentence denotes A duration of 5 days is appropriate for most patients.
T15 1319-1457 Sentence denotes The panel recommends against the use of hydroxychloroquine or lopinavir-ritonavir (or other protease inhibitors) for COVID-19 in children.
T16 1459-1470 Sentence denotes Conclusions
T17 1471-1564 Sentence denotes Antiviral therapy for COVID-19 is not necessary for the great majority of pediatric patients.
T18 1565-1692 Sentence denotes For children with severe or critical disease, this guidance offers an approach for decision-making regarding use of remdesivir.