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LitCovid-PD-FMA-UBERON

LitCovid-PD-UBERON

LitCovid-PD-MONDO

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T133","span":{"begin":509,"end":522},"obj":"Disease"},{"id":"T134","span":{"begin":773,"end":793},"obj":"Disease"},{"id":"T135","span":{"begin":887,"end":899},"obj":"Disease"},{"id":"T136","span":{"begin":929,"end":942},"obj":"Disease"},{"id":"T137","span":{"begin":1153,"end":1164},"obj":"Disease"},{"id":"T138","span":{"begin":1358,"end":1370},"obj":"Disease"},{"id":"T139","span":{"begin":1819,"end":1830},"obj":"Disease"},{"id":"T140","span":{"begin":2046,"end":2058},"obj":"Disease"}],"attributes":[{"id":"A133","pred":"mondo_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/MONDO_0002123"},{"id":"A134","pred":"mondo_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/MONDO_0005267"},{"id":"A135","pred":"mondo_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A136","pred":"mondo_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/MONDO_0002123"},{"id":"A137","pred":"mondo_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/MONDO_0004496"},{"id":"A138","pred":"mondo_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/MONDO_0005904"},{"id":"A139","pred":"mondo_id","subj":"T139","obj":"http://purl.obolibrary.org/obo/MONDO_0004496"},{"id":"A140","pred":"mondo_id","subj":"T140","obj":"http://purl.obolibrary.org/obo/MONDO_0005904"}],"text":"Heart Findings\n\nMacroscopic Findings.\nThe hearts in all group 1 and 2 patients showed increased size and weight, hypertrophy, and dilation of the left and right atria and ventricles. The myocardium appeared pale and flabby, and endocardium showed punctuate petechial hemorrhages (Figure 4A1). Some patients in group 1 had pathological changes that were related to the patient’s age. These included myocardial ischemic or inflammatory changes, hypertensive changes of the left ventricular cavity, and valvular calcification of the mitral annulus and aortic valve (Figure 4A2).\nFigure 4. Histological changes in heart. A1, Hearts were increased in size and weight. The myocardium appeared pale and flabby. Endocardium showed punctuate petechial hemorrhages. A2, Age-related disease of the heart was represented by volume changes of the left ventricular cavity and exacerbated by systemic hypertension with valve changes including calcification of the mitral annulus and aortic valve. A3 and A4, Heart tissue shows myocytes hypertrophy, and variable degrees of interstitial and vascular fibrosis with mononuclear cells infiltrating adventitia. B1, Active myocarditis was characterized by mononuclear, predominantly lymphocytic infiltrate, associated with focal myocytes necrosis (B2). B3, Fibrinous, hemorrhagic areas with myofibers disarray were present. B4, Pericarditis with lymphocytic infiltration and increase in fibrous tissue was seen in all patients. Abbreviation: H\u0026E, haematoxylin and eosin. Scale bars: A3 and B4, 21 µm; A4–B2,7 µm; B3, 14 µm.\n\nMicroscopic Findings.\nMicroscopic changes seen were hypertrophy of myocytes and variable degrees of interstitial and vascular fibrosis (Figure 4A3 and 4A4). Mononuclear cells infiltrating adventitia was found predominantly in group 2 patients (Figure 4A4). Active myocarditis (Figure 4B1) characterized by mononuclear, predominantly lymphocytic, infiltrate, and was associated with focal myocytes necrosis (Figure 4B2), fibrinous, and hemorrhagic areas with myofibers disarray (Figure 4B3). Pericarditis (fibrinous or fibrous) was seen mainly in group 2 patients (Figure 4B4)."}

LitCovid-PD-CLO

LitCovid-PubTator

LitCovid-PD-HP

{"project":"LitCovid-PD-HP","denotations":[{"id":"T57","span":{"begin":878,"end":899},"obj":"Phenotype"},{"id":"T58","span":{"begin":1153,"end":1164},"obj":"Phenotype"},{"id":"T59","span":{"begin":1321,"end":1339},"obj":"Phenotype"},{"id":"T60","span":{"begin":1358,"end":1370},"obj":"Phenotype"},{"id":"T61","span":{"begin":1819,"end":1830},"obj":"Phenotype"},{"id":"T62","span":{"begin":2013,"end":2031},"obj":"Phenotype"},{"id":"T63","span":{"begin":2046,"end":2058},"obj":"Phenotype"}],"attributes":[{"id":"A57","pred":"hp_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A58","pred":"hp_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/HP_0012819"},{"id":"A59","pred":"hp_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/HP_0031318"},{"id":"A60","pred":"hp_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/HP_0001701"},{"id":"A61","pred":"hp_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/HP_0012819"},{"id":"A62","pred":"hp_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/HP_0031318"},{"id":"A63","pred":"hp_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/HP_0001701"}],"text":"Heart Findings\n\nMacroscopic Findings.\nThe hearts in all group 1 and 2 patients showed increased size and weight, hypertrophy, and dilation of the left and right atria and ventricles. The myocardium appeared pale and flabby, and endocardium showed punctuate petechial hemorrhages (Figure 4A1). Some patients in group 1 had pathological changes that were related to the patient’s age. These included myocardial ischemic or inflammatory changes, hypertensive changes of the left ventricular cavity, and valvular calcification of the mitral annulus and aortic valve (Figure 4A2).\nFigure 4. Histological changes in heart. A1, Hearts were increased in size and weight. The myocardium appeared pale and flabby. Endocardium showed punctuate petechial hemorrhages. A2, Age-related disease of the heart was represented by volume changes of the left ventricular cavity and exacerbated by systemic hypertension with valve changes including calcification of the mitral annulus and aortic valve. A3 and A4, Heart tissue shows myocytes hypertrophy, and variable degrees of interstitial and vascular fibrosis with mononuclear cells infiltrating adventitia. B1, Active myocarditis was characterized by mononuclear, predominantly lymphocytic infiltrate, associated with focal myocytes necrosis (B2). B3, Fibrinous, hemorrhagic areas with myofibers disarray were present. B4, Pericarditis with lymphocytic infiltration and increase in fibrous tissue was seen in all patients. Abbreviation: H\u0026E, haematoxylin and eosin. Scale bars: A3 and B4, 21 µm; A4–B2,7 µm; B3, 14 µm.\n\nMicroscopic Findings.\nMicroscopic changes seen were hypertrophy of myocytes and variable degrees of interstitial and vascular fibrosis (Figure 4A3 and 4A4). Mononuclear cells infiltrating adventitia was found predominantly in group 2 patients (Figure 4A4). Active myocarditis (Figure 4B1) characterized by mononuclear, predominantly lymphocytic, infiltrate, and was associated with focal myocytes necrosis (Figure 4B2), fibrinous, and hemorrhagic areas with myofibers disarray (Figure 4B3). Pericarditis (fibrinous or fibrous) was seen mainly in group 2 patients (Figure 4B4)."}

LitCovid-PD-GO-BP

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T13","span":{"begin":1268,"end":1276},"obj":"http://purl.obolibrary.org/obo/GO_0070265"},{"id":"T14","span":{"begin":1268,"end":1276},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T15","span":{"begin":1268,"end":1276},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T16","span":{"begin":1268,"end":1276},"obj":"http://purl.obolibrary.org/obo/GO_0001906"},{"id":"T17","span":{"begin":1952,"end":1960},"obj":"http://purl.obolibrary.org/obo/GO_0070265"},{"id":"T18","span":{"begin":1952,"end":1960},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T19","span":{"begin":1952,"end":1960},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T20","span":{"begin":1952,"end":1960},"obj":"http://purl.obolibrary.org/obo/GO_0001906"}],"text":"Heart Findings\n\nMacroscopic Findings.\nThe hearts in all group 1 and 2 patients showed increased size and weight, hypertrophy, and dilation of the left and right atria and ventricles. The myocardium appeared pale and flabby, and endocardium showed punctuate petechial hemorrhages (Figure 4A1). Some patients in group 1 had pathological changes that were related to the patient’s age. These included myocardial ischemic or inflammatory changes, hypertensive changes of the left ventricular cavity, and valvular calcification of the mitral annulus and aortic valve (Figure 4A2).\nFigure 4. Histological changes in heart. A1, Hearts were increased in size and weight. The myocardium appeared pale and flabby. Endocardium showed punctuate petechial hemorrhages. A2, Age-related disease of the heart was represented by volume changes of the left ventricular cavity and exacerbated by systemic hypertension with valve changes including calcification of the mitral annulus and aortic valve. A3 and A4, Heart tissue shows myocytes hypertrophy, and variable degrees of interstitial and vascular fibrosis with mononuclear cells infiltrating adventitia. B1, Active myocarditis was characterized by mononuclear, predominantly lymphocytic infiltrate, associated with focal myocytes necrosis (B2). B3, Fibrinous, hemorrhagic areas with myofibers disarray were present. B4, Pericarditis with lymphocytic infiltration and increase in fibrous tissue was seen in all patients. Abbreviation: H\u0026E, haematoxylin and eosin. Scale bars: A3 and B4, 21 µm; A4–B2,7 µm; B3, 14 µm.\n\nMicroscopic Findings.\nMicroscopic changes seen were hypertrophy of myocytes and variable degrees of interstitial and vascular fibrosis (Figure 4A3 and 4A4). Mononuclear cells infiltrating adventitia was found predominantly in group 2 patients (Figure 4A4). Active myocarditis (Figure 4B1) characterized by mononuclear, predominantly lymphocytic, infiltrate, and was associated with focal myocytes necrosis (Figure 4B2), fibrinous, and hemorrhagic areas with myofibers disarray (Figure 4B3). Pericarditis (fibrinous or fibrous) was seen mainly in group 2 patients (Figure 4B4)."}

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T195","span":{"begin":0,"end":14},"obj":"Sentence"},{"id":"T196","span":{"begin":16,"end":37},"obj":"Sentence"},{"id":"T197","span":{"begin":38,"end":182},"obj":"Sentence"},{"id":"T198","span":{"begin":183,"end":292},"obj":"Sentence"},{"id":"T199","span":{"begin":293,"end":382},"obj":"Sentence"},{"id":"T200","span":{"begin":383,"end":575},"obj":"Sentence"},{"id":"T201","span":{"begin":576,"end":585},"obj":"Sentence"},{"id":"T202","span":{"begin":587,"end":617},"obj":"Sentence"},{"id":"T203","span":{"begin":618,"end":663},"obj":"Sentence"},{"id":"T204","span":{"begin":664,"end":704},"obj":"Sentence"},{"id":"T205","span":{"begin":705,"end":756},"obj":"Sentence"},{"id":"T206","span":{"begin":757,"end":982},"obj":"Sentence"},{"id":"T207","span":{"begin":983,"end":1141},"obj":"Sentence"},{"id":"T208","span":{"begin":1142,"end":1282},"obj":"Sentence"},{"id":"T209","span":{"begin":1283,"end":1353},"obj":"Sentence"},{"id":"T210","span":{"begin":1354,"end":1457},"obj":"Sentence"},{"id":"T211","span":{"begin":1458,"end":1500},"obj":"Sentence"},{"id":"T212","span":{"begin":1501,"end":1553},"obj":"Sentence"},{"id":"T213","span":{"begin":1555,"end":1576},"obj":"Sentence"},{"id":"T214","span":{"begin":1577,"end":1711},"obj":"Sentence"},{"id":"T215","span":{"begin":1712,"end":1811},"obj":"Sentence"},{"id":"T216","span":{"begin":1812,"end":2045},"obj":"Sentence"},{"id":"T217","span":{"begin":2046,"end":2131},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Heart Findings\n\nMacroscopic Findings.\nThe hearts in all group 1 and 2 patients showed increased size and weight, hypertrophy, and dilation of the left and right atria and ventricles. The myocardium appeared pale and flabby, and endocardium showed punctuate petechial hemorrhages (Figure 4A1). Some patients in group 1 had pathological changes that were related to the patient’s age. These included myocardial ischemic or inflammatory changes, hypertensive changes of the left ventricular cavity, and valvular calcification of the mitral annulus and aortic valve (Figure 4A2).\nFigure 4. Histological changes in heart. A1, Hearts were increased in size and weight. The myocardium appeared pale and flabby. Endocardium showed punctuate petechial hemorrhages. A2, Age-related disease of the heart was represented by volume changes of the left ventricular cavity and exacerbated by systemic hypertension with valve changes including calcification of the mitral annulus and aortic valve. A3 and A4, Heart tissue shows myocytes hypertrophy, and variable degrees of interstitial and vascular fibrosis with mononuclear cells infiltrating adventitia. B1, Active myocarditis was characterized by mononuclear, predominantly lymphocytic infiltrate, associated with focal myocytes necrosis (B2). B3, Fibrinous, hemorrhagic areas with myofibers disarray were present. B4, Pericarditis with lymphocytic infiltration and increase in fibrous tissue was seen in all patients. Abbreviation: H\u0026E, haematoxylin and eosin. Scale bars: A3 and B4, 21 µm; A4–B2,7 µm; B3, 14 µm.\n\nMicroscopic Findings.\nMicroscopic changes seen were hypertrophy of myocytes and variable degrees of interstitial and vascular fibrosis (Figure 4A3 and 4A4). Mononuclear cells infiltrating adventitia was found predominantly in group 2 patients (Figure 4A4). Active myocarditis (Figure 4B1) characterized by mononuclear, predominantly lymphocytic, infiltrate, and was associated with focal myocytes necrosis (Figure 4B2), fibrinous, and hemorrhagic areas with myofibers disarray (Figure 4B3). Pericarditis (fibrinous or fibrous) was seen mainly in group 2 patients (Figure 4B4)."}

PMC:7543426 / 15833-17964 JSONTXT

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PMC:7543426 / 15833-17964 JSON TXT