PMC:7537084 / 5173-7778
Annnotations
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T36","span":{"begin":246,"end":250},"obj":"Disease"},{"id":"T37","span":{"begin":257,"end":266},"obj":"Disease"},{"id":"T38","span":{"begin":314,"end":318},"obj":"Disease"},{"id":"T39","span":{"begin":325,"end":334},"obj":"Disease"},{"id":"T40","span":{"begin":419,"end":427},"obj":"Disease"},{"id":"T41","span":{"begin":476,"end":484},"obj":"Disease"},{"id":"T42","span":{"begin":525,"end":533},"obj":"Disease"},{"id":"T43","span":{"begin":667,"end":671},"obj":"Disease"},{"id":"T44","span":{"begin":717,"end":734},"obj":"Disease"},{"id":"T45","span":{"begin":736,"end":748},"obj":"Disease"},{"id":"T46","span":{"begin":758,"end":774},"obj":"Disease"},{"id":"T47","span":{"begin":776,"end":779},"obj":"Disease"},{"id":"T49","span":{"begin":782,"end":819},"obj":"Disease"},{"id":"T50","span":{"begin":802,"end":819},"obj":"Disease"},{"id":"T51","span":{"begin":821,"end":825},"obj":"Disease"},{"id":"T52","span":{"begin":883,"end":891},"obj":"Disease"},{"id":"T53","span":{"begin":910,"end":918},"obj":"Disease"},{"id":"T54","span":{"begin":943,"end":951},"obj":"Disease"},{"id":"T55","span":{"begin":1079,"end":1087},"obj":"Disease"},{"id":"T56","span":{"begin":1255,"end":1263},"obj":"Disease"},{"id":"T57","span":{"begin":1273,"end":1281},"obj":"Disease"},{"id":"T58","span":{"begin":1728,"end":1736},"obj":"Disease"},{"id":"T59","span":{"begin":1779,"end":1791},"obj":"Disease"},{"id":"T60","span":{"begin":1835,"end":1857},"obj":"Disease"},{"id":"T61","span":{"begin":1899,"end":1903},"obj":"Disease"},{"id":"T62","span":{"begin":2180,"end":2223},"obj":"Disease"},{"id":"T63","span":{"begin":2180,"end":2184},"obj":"Disease"},{"id":"T64","span":{"begin":2206,"end":2223},"obj":"Disease"},{"id":"T65","span":{"begin":2225,"end":2233},"obj":"Disease"},{"id":"T66","span":{"begin":2235,"end":2259},"obj":"Disease"},{"id":"T67","span":{"begin":2380,"end":2388},"obj":"Disease"}],"attributes":[{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A45","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A46","pred":"mondo_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/MONDO_0005385"},{"id":"A47","pred":"mondo_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/MONDO_0005010"},{"id":"A48","pred":"mondo_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/MONDO_0018922"},{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0005002"},{"id":"A50","pred":"mondo_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/MONDO_0005275"},{"id":"A51","pred":"mondo_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/MONDO_0005002"},{"id":"A52","pred":"mondo_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A53","pred":"mondo_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A54","pred":"mondo_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A55","pred":"mondo_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A56","pred":"mondo_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A57","pred":"mondo_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A58","pred":"mondo_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A59","pred":"mondo_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A60","pred":"mondo_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/MONDO_0004995"},{"id":"A61","pred":"mondo_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/MONDO_0005002"},{"id":"A62","pred":"mondo_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/MONDO_0005002"},{"id":"A63","pred":"mondo_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/MONDO_0005002"},{"id":"A64","pred":"mondo_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/MONDO_0005275"},{"id":"A65","pred":"mondo_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A66","pred":"mondo_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A67","pred":"mondo_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"3.1 Demographic and clinical characteristics of patients\nA total of 50 patients were included in this study (27 males and 23 females) with a mean age of 66.60 (SD, 12.81; range, 34–83) years old. Twenty‐four patients were confirmed positive for SARS‐CoV‐2 infection by RT‐PCR, while 26 patients were negative for SARS‐CoV‐2 infection. Patients' demographic characteristics were summarized in Table 1. The mean age for COVID‐19 patients was 65.38 (SD, 9.6; range, 47–83). The COVID‐19 patients had older ages compared to non‐COVID‐19 patients with a mean age of 56.3 (SD, 14.0; range, 34–83; p = .011). The main symptoms at admission were fever, shortness of breath, ARDS, cough, and fatigue. Comorbidities including diabetes mellitus, hypertension, cardiac vascular disease (CAD), chronic obstructive pulmonary disease (COPD), and malignancies were significantly more common in the COVID‐19 patients than non‐COVID‐19 patients (p \u003c .05). For COVID‐19 patients, 11 patients died during hospitalization, 11 patients were discharged, and two patients remained in hospital. For non‐COVID‐19 patients, 6 patients died, 19 patients were discharged, and 1 patient was still in the hospital.\nTable 1 The demographic and clinical characteristics of 50 suspected COVID‐19 patients\nCOVID‐19 status\nCharacteristics All patients (n = 50) Negative (n = 26) Positive (n = 24) p Value\nAge, years (mean ± SD, median) 60.66 ± 12.81 (62) 56.31 ± 14.00 (60.5) 65.38 ± 9.60 (66.5) .011*\nSex, n (%)\nMale 27 (54%) 12 (46.15%) 15 (62.5%) .247\nFemale 23 (46%) 14 (53.85) 9 (37.5%)\nRace, n (%)\nWhite 13 (26%) 10 (38.46%) 3 (12.5%) .054\nBlack 35 (70%) 16 (61.54%) 19 (79.17%)\nOther 2 (4%) 0 (0%) 2 (8.33%)\nComorbidities, n (%)\nDiabetes 16 (32%) 5 (19.23%) 11 (45.83%) .044*\nHypertension 32 (64%) 12 (46.15%) 20 (83.33%) .006*\nCardiovascular disease 15 (30%) 12 (46.15%) 3 (12.5%) .009*\nCOPD 15 (30%) 11 (42.31%) 4 (16.67%) .048*\nMalignancy 11 (22%) 9 (34.62%) 2 (8.33%) .025*\nClinical outcome, n (%)\nRemained in hospital 3 (6%) 1 (3.85%) 2 (8.34%)\nDischarged 30 (60%) 19 (73.08%) 11 (45.83%) .121\nDied 17 (34%) 6 (23.07%) 11 (45.83%)\nAbbreviations: COPD, chronic obstructive pulmonary disease; COVID‐19, coronavirus disease 2019.\n* p \u003c .05.\nJohn Wiley \u0026 Sons, Ltd. This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T42","span":{"begin":58,"end":59},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T43","span":{"begin":110,"end":112},"obj":"http://purl.obolibrary.org/obo/CLO_0050509"},{"id":"T44","span":{"begin":113,"end":118},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T45","span":{"begin":113,"end":118},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T46","span":{"begin":126,"end":133},"obj":"http://purl.obolibrary.org/obo/UBERON_0003100"},{"id":"T47","span":{"begin":140,"end":141},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T48","span":{"begin":179,"end":181},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T49","span":{"begin":548,"end":549},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T50","span":{"begin":585,"end":587},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T51","span":{"begin":962,"end":964},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T52","span":{"begin":1003,"end":1005},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T53","span":{"begin":1488,"end":1492},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T54","span":{"begin":1488,"end":1492},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T55","span":{"begin":1494,"end":1496},"obj":"http://purl.obolibrary.org/obo/CLO_0050509"},{"id":"T56","span":{"begin":1534,"end":1540},"obj":"http://purl.obolibrary.org/obo/UBERON_0003100"},{"id":"T57","span":{"begin":1639,"end":1641},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T58","span":{"begin":1760,"end":1762},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T59","span":{"begin":1915,"end":1917},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T60","span":{"begin":1958,"end":1960},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T61","span":{"begin":1962,"end":1964},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T62","span":{"begin":2107,"end":2109},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T63","span":{"begin":2121,"end":2124},"obj":"http://purl.obolibrary.org/obo/CLO_0001053"},{"id":"T64","span":{"begin":2135,"end":2137},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T65","span":{"begin":2153,"end":2155},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"}],"text":"3.1 Demographic and clinical characteristics of patients\nA total of 50 patients were included in this study (27 males and 23 females) with a mean age of 66.60 (SD, 12.81; range, 34–83) years old. Twenty‐four patients were confirmed positive for SARS‐CoV‐2 infection by RT‐PCR, while 26 patients were negative for SARS‐CoV‐2 infection. Patients' demographic characteristics were summarized in Table 1. The mean age for COVID‐19 patients was 65.38 (SD, 9.6; range, 47–83). The COVID‐19 patients had older ages compared to non‐COVID‐19 patients with a mean age of 56.3 (SD, 14.0; range, 34–83; p = .011). The main symptoms at admission were fever, shortness of breath, ARDS, cough, and fatigue. Comorbidities including diabetes mellitus, hypertension, cardiac vascular disease (CAD), chronic obstructive pulmonary disease (COPD), and malignancies were significantly more common in the COVID‐19 patients than non‐COVID‐19 patients (p \u003c .05). For COVID‐19 patients, 11 patients died during hospitalization, 11 patients were discharged, and two patients remained in hospital. For non‐COVID‐19 patients, 6 patients died, 19 patients were discharged, and 1 patient was still in the hospital.\nTable 1 The demographic and clinical characteristics of 50 suspected COVID‐19 patients\nCOVID‐19 status\nCharacteristics All patients (n = 50) Negative (n = 26) Positive (n = 24) p Value\nAge, years (mean ± SD, median) 60.66 ± 12.81 (62) 56.31 ± 14.00 (60.5) 65.38 ± 9.60 (66.5) .011*\nSex, n (%)\nMale 27 (54%) 12 (46.15%) 15 (62.5%) .247\nFemale 23 (46%) 14 (53.85) 9 (37.5%)\nRace, n (%)\nWhite 13 (26%) 10 (38.46%) 3 (12.5%) .054\nBlack 35 (70%) 16 (61.54%) 19 (79.17%)\nOther 2 (4%) 0 (0%) 2 (8.33%)\nComorbidities, n (%)\nDiabetes 16 (32%) 5 (19.23%) 11 (45.83%) .044*\nHypertension 32 (64%) 12 (46.15%) 20 (83.33%) .006*\nCardiovascular disease 15 (30%) 12 (46.15%) 3 (12.5%) .009*\nCOPD 15 (30%) 11 (42.31%) 4 (16.67%) .048*\nMalignancy 11 (22%) 9 (34.62%) 2 (8.33%) .025*\nClinical outcome, n (%)\nRemained in hospital 3 (6%) 1 (3.85%) 2 (8.34%)\nDischarged 30 (60%) 19 (73.08%) 11 (45.83%) .121\nDied 17 (34%) 6 (23.07%) 11 (45.83%)\nAbbreviations: COPD, chronic obstructive pulmonary disease; COVID‐19, coronavirus disease 2019.\n* p \u003c .05.\nJohn Wiley \u0026 Sons, Ltd. This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T25","span":{"begin":161,"end":163},"obj":"Chemical"},{"id":"T26","span":{"begin":448,"end":450},"obj":"Chemical"},{"id":"T27","span":{"begin":568,"end":570},"obj":"Chemical"},{"id":"T28","span":{"begin":1395,"end":1397},"obj":"Chemical"}],"attributes":[{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_74807"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_74807"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_74807"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_74807"}],"text":"3.1 Demographic and clinical characteristics of patients\nA total of 50 patients were included in this study (27 males and 23 females) with a mean age of 66.60 (SD, 12.81; range, 34–83) years old. Twenty‐four patients were confirmed positive for SARS‐CoV‐2 infection by RT‐PCR, while 26 patients were negative for SARS‐CoV‐2 infection. Patients' demographic characteristics were summarized in Table 1. The mean age for COVID‐19 patients was 65.38 (SD, 9.6; range, 47–83). The COVID‐19 patients had older ages compared to non‐COVID‐19 patients with a mean age of 56.3 (SD, 14.0; range, 34–83; p = .011). The main symptoms at admission were fever, shortness of breath, ARDS, cough, and fatigue. Comorbidities including diabetes mellitus, hypertension, cardiac vascular disease (CAD), chronic obstructive pulmonary disease (COPD), and malignancies were significantly more common in the COVID‐19 patients than non‐COVID‐19 patients (p \u003c .05). For COVID‐19 patients, 11 patients died during hospitalization, 11 patients were discharged, and two patients remained in hospital. For non‐COVID‐19 patients, 6 patients died, 19 patients were discharged, and 1 patient was still in the hospital.\nTable 1 The demographic and clinical characteristics of 50 suspected COVID‐19 patients\nCOVID‐19 status\nCharacteristics All patients (n = 50) Negative (n = 26) Positive (n = 24) p Value\nAge, years (mean ± SD, median) 60.66 ± 12.81 (62) 56.31 ± 14.00 (60.5) 65.38 ± 9.60 (66.5) .011*\nSex, n (%)\nMale 27 (54%) 12 (46.15%) 15 (62.5%) .247\nFemale 23 (46%) 14 (53.85) 9 (37.5%)\nRace, n (%)\nWhite 13 (26%) 10 (38.46%) 3 (12.5%) .054\nBlack 35 (70%) 16 (61.54%) 19 (79.17%)\nOther 2 (4%) 0 (0%) 2 (8.33%)\nComorbidities, n (%)\nDiabetes 16 (32%) 5 (19.23%) 11 (45.83%) .044*\nHypertension 32 (64%) 12 (46.15%) 20 (83.33%) .006*\nCardiovascular disease 15 (30%) 12 (46.15%) 3 (12.5%) .009*\nCOPD 15 (30%) 11 (42.31%) 4 (16.67%) .048*\nMalignancy 11 (22%) 9 (34.62%) 2 (8.33%) .025*\nClinical outcome, n (%)\nRemained in hospital 3 (6%) 1 (3.85%) 2 (8.34%)\nDischarged 30 (60%) 19 (73.08%) 11 (45.83%) .121\nDied 17 (34%) 6 (23.07%) 11 (45.83%)\nAbbreviations: COPD, chronic obstructive pulmonary disease; COVID‐19, coronavirus disease 2019.\n* p \u003c .05.\nJohn Wiley \u0026 Sons, Ltd. This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency."}
LitCovid-PD-HP
{"project":"LitCovid-PD-HP","denotations":[{"id":"T6","span":{"begin":639,"end":644},"obj":"Phenotype"},{"id":"T7","span":{"begin":646,"end":665},"obj":"Phenotype"},{"id":"T8","span":{"begin":673,"end":678},"obj":"Phenotype"},{"id":"T9","span":{"begin":684,"end":691},"obj":"Phenotype"},{"id":"T10","span":{"begin":717,"end":734},"obj":"Phenotype"},{"id":"T11","span":{"begin":736,"end":748},"obj":"Phenotype"},{"id":"T12","span":{"begin":782,"end":819},"obj":"Phenotype"},{"id":"T13","span":{"begin":821,"end":825},"obj":"Phenotype"},{"id":"T14","span":{"begin":1779,"end":1791},"obj":"Phenotype"},{"id":"T15","span":{"begin":1835,"end":1857},"obj":"Phenotype"},{"id":"T16","span":{"begin":1899,"end":1903},"obj":"Phenotype"},{"id":"T17","span":{"begin":2180,"end":2184},"obj":"Phenotype"},{"id":"T18","span":{"begin":2186,"end":2223},"obj":"Phenotype"}],"attributes":[{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0012735"},{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0012378"},{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0000819"},{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0006510"},{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0006510"},{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0001626"},{"id":"A16","pred":"hp_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/HP_0006510"},{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0006510"},{"id":"A18","pred":"hp_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/HP_0006510"}],"text":"3.1 Demographic and clinical characteristics of patients\nA total of 50 patients were included in this study (27 males and 23 females) with a mean age of 66.60 (SD, 12.81; range, 34–83) years old. Twenty‐four patients were confirmed positive for SARS‐CoV‐2 infection by RT‐PCR, while 26 patients were negative for SARS‐CoV‐2 infection. Patients' demographic characteristics were summarized in Table 1. The mean age for COVID‐19 patients was 65.38 (SD, 9.6; range, 47–83). The COVID‐19 patients had older ages compared to non‐COVID‐19 patients with a mean age of 56.3 (SD, 14.0; range, 34–83; p = .011). The main symptoms at admission were fever, shortness of breath, ARDS, cough, and fatigue. Comorbidities including diabetes mellitus, hypertension, cardiac vascular disease (CAD), chronic obstructive pulmonary disease (COPD), and malignancies were significantly more common in the COVID‐19 patients than non‐COVID‐19 patients (p \u003c .05). For COVID‐19 patients, 11 patients died during hospitalization, 11 patients were discharged, and two patients remained in hospital. For non‐COVID‐19 patients, 6 patients died, 19 patients were discharged, and 1 patient was still in the hospital.\nTable 1 The demographic and clinical characteristics of 50 suspected COVID‐19 patients\nCOVID‐19 status\nCharacteristics All patients (n = 50) Negative (n = 26) Positive (n = 24) p Value\nAge, years (mean ± SD, median) 60.66 ± 12.81 (62) 56.31 ± 14.00 (60.5) 65.38 ± 9.60 (66.5) .011*\nSex, n (%)\nMale 27 (54%) 12 (46.15%) 15 (62.5%) .247\nFemale 23 (46%) 14 (53.85) 9 (37.5%)\nRace, n (%)\nWhite 13 (26%) 10 (38.46%) 3 (12.5%) .054\nBlack 35 (70%) 16 (61.54%) 19 (79.17%)\nOther 2 (4%) 0 (0%) 2 (8.33%)\nComorbidities, n (%)\nDiabetes 16 (32%) 5 (19.23%) 11 (45.83%) .044*\nHypertension 32 (64%) 12 (46.15%) 20 (83.33%) .006*\nCardiovascular disease 15 (30%) 12 (46.15%) 3 (12.5%) .009*\nCOPD 15 (30%) 11 (42.31%) 4 (16.67%) .048*\nMalignancy 11 (22%) 9 (34.62%) 2 (8.33%) .025*\nClinical outcome, n (%)\nRemained in hospital 3 (6%) 1 (3.85%) 2 (8.34%)\nDischarged 30 (60%) 19 (73.08%) 11 (45.83%) .121\nDied 17 (34%) 6 (23.07%) 11 (45.83%)\nAbbreviations: COPD, chronic obstructive pulmonary disease; COVID‐19, coronavirus disease 2019.\n* p \u003c .05.\nJohn Wiley \u0026 Sons, Ltd. This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T49","span":{"begin":0,"end":57},"obj":"Sentence"},{"id":"T50","span":{"begin":58,"end":196},"obj":"Sentence"},{"id":"T51","span":{"begin":197,"end":335},"obj":"Sentence"},{"id":"T52","span":{"begin":336,"end":401},"obj":"Sentence"},{"id":"T53","span":{"begin":402,"end":471},"obj":"Sentence"},{"id":"T54","span":{"begin":472,"end":602},"obj":"Sentence"},{"id":"T55","span":{"begin":603,"end":692},"obj":"Sentence"},{"id":"T56","span":{"begin":693,"end":938},"obj":"Sentence"},{"id":"T57","span":{"begin":939,"end":1070},"obj":"Sentence"},{"id":"T58","span":{"begin":1071,"end":1184},"obj":"Sentence"},{"id":"T59","span":{"begin":1185,"end":1272},"obj":"Sentence"},{"id":"T60","span":{"begin":1273,"end":1288},"obj":"Sentence"},{"id":"T61","span":{"begin":1289,"end":1375},"obj":"Sentence"},{"id":"T62","span":{"begin":1376,"end":1476},"obj":"Sentence"},{"id":"T63","span":{"begin":1477,"end":1487},"obj":"Sentence"},{"id":"T64","span":{"begin":1488,"end":1533},"obj":"Sentence"},{"id":"T65","span":{"begin":1534,"end":1573},"obj":"Sentence"},{"id":"T66","span":{"begin":1574,"end":1585},"obj":"Sentence"},{"id":"T67","span":{"begin":1586,"end":1631},"obj":"Sentence"},{"id":"T68","span":{"begin":1632,"end":1673},"obj":"Sentence"},{"id":"T69","span":{"begin":1674,"end":1706},"obj":"Sentence"},{"id":"T70","span":{"begin":1707,"end":1727},"obj":"Sentence"},{"id":"T71","span":{"begin":1728,"end":1778},"obj":"Sentence"},{"id":"T72","span":{"begin":1779,"end":1834},"obj":"Sentence"},{"id":"T73","span":{"begin":1835,"end":1898},"obj":"Sentence"},{"id":"T74","span":{"begin":1899,"end":1945},"obj":"Sentence"},{"id":"T75","span":{"begin":1946,"end":1996},"obj":"Sentence"},{"id":"T76","span":{"begin":1997,"end":2020},"obj":"Sentence"},{"id":"T77","span":{"begin":2021,"end":2071},"obj":"Sentence"},{"id":"T78","span":{"begin":2072,"end":2124},"obj":"Sentence"},{"id":"T79","span":{"begin":2125,"end":2164},"obj":"Sentence"},{"id":"T80","span":{"begin":2165,"end":2260},"obj":"Sentence"},{"id":"T81","span":{"begin":2261,"end":2273},"obj":"Sentence"},{"id":"T82","span":{"begin":2274,"end":2297},"obj":"Sentence"},{"id":"T83","span":{"begin":2298,"end":2422},"obj":"Sentence"},{"id":"T84","span":{"begin":2423,"end":2605},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"3.1 Demographic and clinical characteristics of patients\nA total of 50 patients were included in this study (27 males and 23 females) with a mean age of 66.60 (SD, 12.81; range, 34–83) years old. Twenty‐four patients were confirmed positive for SARS‐CoV‐2 infection by RT‐PCR, while 26 patients were negative for SARS‐CoV‐2 infection. Patients' demographic characteristics were summarized in Table 1. The mean age for COVID‐19 patients was 65.38 (SD, 9.6; range, 47–83). The COVID‐19 patients had older ages compared to non‐COVID‐19 patients with a mean age of 56.3 (SD, 14.0; range, 34–83; p = .011). The main symptoms at admission were fever, shortness of breath, ARDS, cough, and fatigue. Comorbidities including diabetes mellitus, hypertension, cardiac vascular disease (CAD), chronic obstructive pulmonary disease (COPD), and malignancies were significantly more common in the COVID‐19 patients than non‐COVID‐19 patients (p \u003c .05). For COVID‐19 patients, 11 patients died during hospitalization, 11 patients were discharged, and two patients remained in hospital. For non‐COVID‐19 patients, 6 patients died, 19 patients were discharged, and 1 patient was still in the hospital.\nTable 1 The demographic and clinical characteristics of 50 suspected COVID‐19 patients\nCOVID‐19 status\nCharacteristics All patients (n = 50) Negative (n = 26) Positive (n = 24) p Value\nAge, years (mean ± SD, median) 60.66 ± 12.81 (62) 56.31 ± 14.00 (60.5) 65.38 ± 9.60 (66.5) .011*\nSex, n (%)\nMale 27 (54%) 12 (46.15%) 15 (62.5%) .247\nFemale 23 (46%) 14 (53.85) 9 (37.5%)\nRace, n (%)\nWhite 13 (26%) 10 (38.46%) 3 (12.5%) .054\nBlack 35 (70%) 16 (61.54%) 19 (79.17%)\nOther 2 (4%) 0 (0%) 2 (8.33%)\nComorbidities, n (%)\nDiabetes 16 (32%) 5 (19.23%) 11 (45.83%) .044*\nHypertension 32 (64%) 12 (46.15%) 20 (83.33%) .006*\nCardiovascular disease 15 (30%) 12 (46.15%) 3 (12.5%) .009*\nCOPD 15 (30%) 11 (42.31%) 4 (16.67%) .048*\nMalignancy 11 (22%) 9 (34.62%) 2 (8.33%) .025*\nClinical outcome, n (%)\nRemained in hospital 3 (6%) 1 (3.85%) 2 (8.34%)\nDischarged 30 (60%) 19 (73.08%) 11 (45.83%) .121\nDied 17 (34%) 6 (23.07%) 11 (45.83%)\nAbbreviations: COPD, chronic obstructive pulmonary disease; COVID‐19, coronavirus disease 2019.\n* p \u003c .05.\nJohn Wiley \u0026 Sons, Ltd. This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"216","span":{"begin":72,"end":80},"obj":"Species"},{"id":"217","span":{"begin":209,"end":217},"obj":"Species"},{"id":"218","span":{"begin":287,"end":295},"obj":"Species"},{"id":"219","span":{"begin":336,"end":344},"obj":"Species"},{"id":"220","span":{"begin":428,"end":436},"obj":"Species"},{"id":"221","span":{"begin":485,"end":493},"obj":"Species"},{"id":"222","span":{"begin":534,"end":542},"obj":"Species"},{"id":"223","span":{"begin":892,"end":900},"obj":"Species"},{"id":"224","span":{"begin":919,"end":927},"obj":"Species"},{"id":"225","span":{"begin":952,"end":960},"obj":"Species"},{"id":"226","span":{"begin":965,"end":973},"obj":"Species"},{"id":"227","span":{"begin":1006,"end":1014},"obj":"Species"},{"id":"228","span":{"begin":1040,"end":1048},"obj":"Species"},{"id":"229","span":{"begin":1088,"end":1096},"obj":"Species"},{"id":"230","span":{"begin":1100,"end":1108},"obj":"Species"},{"id":"231","span":{"begin":1118,"end":1126},"obj":"Species"},{"id":"232","span":{"begin":1150,"end":1157},"obj":"Species"},{"id":"233","span":{"begin":246,"end":266},"obj":"Disease"},{"id":"234","span":{"begin":314,"end":334},"obj":"Disease"},{"id":"235","span":{"begin":419,"end":427},"obj":"Disease"},{"id":"236","span":{"begin":476,"end":484},"obj":"Disease"},{"id":"237","span":{"begin":525,"end":533},"obj":"Disease"},{"id":"238","span":{"begin":639,"end":644},"obj":"Disease"},{"id":"239","span":{"begin":646,"end":665},"obj":"Disease"},{"id":"240","span":{"begin":667,"end":671},"obj":"Disease"},{"id":"241","span":{"begin":673,"end":678},"obj":"Disease"},{"id":"242","span":{"begin":684,"end":691},"obj":"Disease"},{"id":"243","span":{"begin":717,"end":734},"obj":"Disease"},{"id":"244","span":{"begin":736,"end":748},"obj":"Disease"},{"id":"245","span":{"begin":750,"end":774},"obj":"Disease"},{"id":"246","span":{"begin":776,"end":779},"obj":"Disease"},{"id":"247","span":{"begin":782,"end":819},"obj":"Disease"},{"id":"248","span":{"begin":821,"end":825},"obj":"Disease"},{"id":"249","span":{"begin":832,"end":844},"obj":"Disease"},{"id":"250","span":{"begin":883,"end":891},"obj":"Disease"},{"id":"251","span":{"begin":910,"end":918},"obj":"Disease"},{"id":"252","span":{"begin":943,"end":951},"obj":"Disease"},{"id":"253","span":{"begin":974,"end":978},"obj":"Disease"},{"id":"254","span":{"begin":1079,"end":1087},"obj":"Disease"},{"id":"255","span":{"begin":1109,"end":1113},"obj":"Disease"},{"id":"263","span":{"begin":1310,"end":1318},"obj":"Species"},{"id":"264","span":{"begin":1273,"end":1281},"obj":"Disease"},{"id":"265","span":{"begin":1728,"end":1736},"obj":"Disease"},{"id":"266","span":{"begin":1779,"end":1791},"obj":"Disease"},{"id":"267","span":{"begin":1835,"end":1857},"obj":"Disease"},{"id":"268","span":{"begin":1899,"end":1903},"obj":"Disease"},{"id":"269","span":{"begin":2125,"end":2129},"obj":"Disease"},{"id":"271","span":{"begin":1255,"end":1263},"obj":"Disease"},{"id":"275","span":{"begin":2180,"end":2184},"obj":"Disease"},{"id":"276","span":{"begin":2186,"end":2223},"obj":"Disease"},{"id":"277","span":{"begin":2235,"end":2259},"obj":"Disease"},{"id":"279","span":{"begin":2380,"end":2388},"obj":"Disease"}],"attributes":[{"id":"A216","pred":"tao:has_database_id","subj":"216","obj":"Tax:9606"},{"id":"A217","pred":"tao:has_database_id","subj":"217","obj":"Tax:9606"},{"id":"A218","pred":"tao:has_database_id","subj":"218","obj":"Tax:9606"},{"id":"A219","pred":"tao:has_database_id","subj":"219","obj":"Tax:9606"},{"id":"A220","pred":"tao:has_database_id","subj":"220","obj":"Tax:9606"},{"id":"A221","pred":"tao:has_database_id","subj":"221","obj":"Tax:9606"},{"id":"A222","pred":"tao:has_database_id","subj":"222","obj":"Tax:9606"},{"id":"A223","pred":"tao:has_database_id","subj":"223","obj":"Tax:9606"},{"id":"A224","pred":"tao:has_database_id","subj":"224","obj":"Tax:9606"},{"id":"A225","pred":"tao:has_database_id","subj":"225","obj":"Tax:9606"},{"id":"A226","pred":"tao:has_database_id","subj":"226","obj":"Tax:9606"},{"id":"A227","pred":"tao:has_database_id","subj":"227","obj":"Tax:9606"},{"id":"A228","pred":"tao:has_database_id","subj":"228","obj":"Tax:9606"},{"id":"A229","pred":"tao:has_database_id","subj":"229","obj":"Tax:9606"},{"id":"A230","pred":"tao:has_database_id","subj":"230","obj":"Tax:9606"},{"id":"A231","pred":"tao:has_database_id","subj":"231","obj":"Tax:9606"},{"id":"A232","pred":"tao:has_database_id","subj":"232","obj":"Tax:9606"},{"id":"A233","pred":"tao:has_database_id","subj":"233","obj":"MESH:C000657245"},{"id":"A234","pred":"tao:has_database_id","subj":"234","obj":"MESH:C000657245"},{"id":"A235","pred":"tao:has_database_id","subj":"235","obj":"MESH:C000657245"},{"id":"A236","pred":"tao:has_database_id","subj":"236","obj":"MESH:C000657245"},{"id":"A237","pred":"tao:has_database_id","subj":"237","obj":"MESH:C000657245"},{"id":"A238","pred":"tao:has_database_id","subj":"238","obj":"MESH:D005334"},{"id":"A239","pred":"tao:has_database_id","subj":"239","obj":"MESH:D004417"},{"id":"A240","pred":"tao:has_database_id","subj":"240","obj":"MESH:D012128"},{"id":"A241","pred":"tao:has_database_id","subj":"241","obj":"MESH:D003371"},{"id":"A242","pred":"tao:has_database_id","subj":"242","obj":"MESH:D005221"},{"id":"A243","pred":"tao:has_database_id","subj":"243","obj":"MESH:D003920"},{"id":"A244","pred":"tao:has_database_id","subj":"244","obj":"MESH:D006973"},{"id":"A245","pred":"tao:has_database_id","subj":"245","obj":"MESH:D006331"},{"id":"A247","pred":"tao:has_database_id","subj":"247","obj":"MESH:D029424"},{"id":"A248","pred":"tao:has_database_id","subj":"248","obj":"MESH:D029424"},{"id":"A249","pred":"tao:has_database_id","subj":"249","obj":"MESH:D009369"},{"id":"A250","pred":"tao:has_database_id","subj":"250","obj":"MESH:C000657245"},{"id":"A251","pred":"tao:has_database_id","subj":"251","obj":"MESH:C000657245"},{"id":"A252","pred":"tao:has_database_id","subj":"252","obj":"MESH:C000657245"},{"id":"A253","pred":"tao:has_database_id","subj":"253","obj":"MESH:D003643"},{"id":"A254","pred":"tao:has_database_id","subj":"254","obj":"MESH:C000657245"},{"id":"A255","pred":"tao:has_database_id","subj":"255","obj":"MESH:D003643"},{"id":"A263","pred":"tao:has_database_id","subj":"263","obj":"Tax:9606"},{"id":"A264","pred":"tao:has_database_id","subj":"264","obj":"MESH:C000657245"},{"id":"A265","pred":"tao:has_database_id","subj":"265","obj":"MESH:D003920"},{"id":"A266","pred":"tao:has_database_id","subj":"266","obj":"MESH:D006973"},{"id":"A267","pred":"tao:has_database_id","subj":"267","obj":"MESH:D002318"},{"id":"A268","pred":"tao:has_database_id","subj":"268","obj":"MESH:D029424"},{"id":"A269","pred":"tao:has_database_id","subj":"269","obj":"MESH:D003643"},{"id":"A271","pred":"tao:has_database_id","subj":"271","obj":"MESH:C000657245"},{"id":"A275","pred":"tao:has_database_id","subj":"275","obj":"MESH:D029424"},{"id":"A276","pred":"tao:has_database_id","subj":"276","obj":"MESH:D029424"},{"id":"A277","pred":"tao:has_database_id","subj":"277","obj":"MESH:C000657245"},{"id":"A279","pred":"tao:has_database_id","subj":"279","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"3.1 Demographic and clinical characteristics of patients\nA total of 50 patients were included in this study (27 males and 23 females) with a mean age of 66.60 (SD, 12.81; range, 34–83) years old. Twenty‐four patients were confirmed positive for SARS‐CoV‐2 infection by RT‐PCR, while 26 patients were negative for SARS‐CoV‐2 infection. Patients' demographic characteristics were summarized in Table 1. The mean age for COVID‐19 patients was 65.38 (SD, 9.6; range, 47–83). The COVID‐19 patients had older ages compared to non‐COVID‐19 patients with a mean age of 56.3 (SD, 14.0; range, 34–83; p = .011). The main symptoms at admission were fever, shortness of breath, ARDS, cough, and fatigue. Comorbidities including diabetes mellitus, hypertension, cardiac vascular disease (CAD), chronic obstructive pulmonary disease (COPD), and malignancies were significantly more common in the COVID‐19 patients than non‐COVID‐19 patients (p \u003c .05). For COVID‐19 patients, 11 patients died during hospitalization, 11 patients were discharged, and two patients remained in hospital. For non‐COVID‐19 patients, 6 patients died, 19 patients were discharged, and 1 patient was still in the hospital.\nTable 1 The demographic and clinical characteristics of 50 suspected COVID‐19 patients\nCOVID‐19 status\nCharacteristics All patients (n = 50) Negative (n = 26) Positive (n = 24) p Value\nAge, years (mean ± SD, median) 60.66 ± 12.81 (62) 56.31 ± 14.00 (60.5) 65.38 ± 9.60 (66.5) .011*\nSex, n (%)\nMale 27 (54%) 12 (46.15%) 15 (62.5%) .247\nFemale 23 (46%) 14 (53.85) 9 (37.5%)\nRace, n (%)\nWhite 13 (26%) 10 (38.46%) 3 (12.5%) .054\nBlack 35 (70%) 16 (61.54%) 19 (79.17%)\nOther 2 (4%) 0 (0%) 2 (8.33%)\nComorbidities, n (%)\nDiabetes 16 (32%) 5 (19.23%) 11 (45.83%) .044*\nHypertension 32 (64%) 12 (46.15%) 20 (83.33%) .006*\nCardiovascular disease 15 (30%) 12 (46.15%) 3 (12.5%) .009*\nCOPD 15 (30%) 11 (42.31%) 4 (16.67%) .048*\nMalignancy 11 (22%) 9 (34.62%) 2 (8.33%) .025*\nClinical outcome, n (%)\nRemained in hospital 3 (6%) 1 (3.85%) 2 (8.34%)\nDischarged 30 (60%) 19 (73.08%) 11 (45.83%) .121\nDied 17 (34%) 6 (23.07%) 11 (45.83%)\nAbbreviations: COPD, chronic obstructive pulmonary disease; COVID‐19, coronavirus disease 2019.\n* p \u003c .05.\nJohn Wiley \u0026 Sons, Ltd. This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency."}